Exam 8: Understanding Carcinoma and Other Neoplasms in the Gastrointestinal Tract: Part B

An elderly male had rectal bleeding. A flat velvety mass was observed in the cecum. The provisional diagnosis was villous adenoma. A partial colectomy was performed. Invasion through the muscularis mucosae, but not into the muscularis propria, was observed on paraffin sections. Therefore, the final diagnosis was:

Regarding G-CSF - the best description of its mechanism of action and role in chemotherapy is

Most common site of metastasis in breast cancer is

Treatment of early stage favorable Hodgkin"s lymphoma …

A 76-year-old male was admitted for symptoms including constipation, change in stool character and weight loss. Colonoscopy revealed multiple polyps in the rectosigmoid area. An adenomatous polyp was removed. Another colonic tumor was seen in the same patient which was flat with irregular "shaggy rug" surface. A biopsy showed frond-like glandular architecture. Atypical epithelial cells in clusters were seen beneath the muscularis mucosae. The most likely diagnosis is:

Mutations in which gene are least likely to be associated with breast cancer if inherited in the germ-line?

Young male with germ cell cancer. He is on bleomycin. etoposide and cisplatinum. What side effect would make you stop the treatment?

Most likely route of ovarian cancer spread:

Which of the following is less likely to be associated with Gallbladder cancer?

14 year old girl with Hodgkin's disease is treated with radiotherapy (mantle field). Which is the most likely secondary carcinoma that could develop

Which of the following chemotherapy drug is likely to be toxic to gonads?

High dose chemotherapy given prior to stem cell transplant may be associated with gonadal failure. Risk is least with the use of

Metastatic renal cell carcinoma, symptomatic:

Incidence of Gallbladder cancer is highest in

Which of the following is least to occur as Gallbladder primary?

Male with bone pain from metastatic prostate cancer will be started on LHRH antagonist. He refuses orchidectomy. His illness will show:

Which one of the following cancers is usually associated with a moderate to high uptake of 18F-fluorodeoxyglucose (18 FFDG)?

On immunohistochemistry, classical Hodgkin"s lymphoma Reed sternberg cells are likely to be

An older woman with breast cancer with bony metastases who was on aminoglutamethonine. Picture of rash which covered right breast and covered left breast a little, small nodules, some dead skin and a few scaly bits. Most likely cause of rash?

A 44-year-old woman presented with post-coital bleeding. Investigation revealed a 2-cm grade 1, stage IB1 squamous cell carcinoma of the cervix. There was no evidence of lymphovascular space invasion. She had completed her family.What is the most appropriate treatment?