Deck 16: Drugs Used in the Treatment of Skin Disorders

Question 1

In general,lesions that are weeping,oozing,vesicular,or crusting should be treated with:

A)Lotions,tinctures,and wet dressings.
B)Creams and ointments.
C)Aerosols and gels.
D)Colloids and emollients.

Answer 1

Lotions,tinctures,and wet dressings.

Question 2

Low-potency topical corticosteroids should be used in which condition?

A)Psoriasis
B)Lichen planus
C)Eczema
D)Allergic contact dermatitis

Answer 2

Psoriasis

Question 3

What additional agent can be used in conjunction with topical anesthetics to prolong their effect?

A)epinephrine
B)norepinephrine
C)morphine
D)dilaudid

Answer 3

epinephrine

Question 4

What is the mechanism of action for tazarotene,which is used in treatment of psoriasis?

A)Causes metabolite binding to retinoic acid receptors and normalize epidermal differentiation
B)Inhibits the transcription of genes to decrease inflammation
C)Binds to vitamin D receptors and promotes the differentiation of keratinocytes
D)Inhibits transcription of cytokines,including interleukin-2

Question 5

What is an advantage of using second-generation antihistamines versus first-generation antihistamines to treat conditions such as urticaria?

A)They cause very little drowsiness.
B)They can be given orally.
C)They can be used in children younger than age 2.
D)They do not need to be administered daily.

Question 6

A burn with blistering and pain is classified as a:

A)First-degree burn.
B)Second-degree burn.
C)Third-degree burn.
D)Fourth-degree burn.

Question 7

Which agent is used to initially clean an open wound but can delay wound healing?

A)chlorhexidine
B)normal saline solution
C)hydrogen peroxide
D)betadine

Question 8

Oral antifungals are known to have which adverse effect?

A)Diarrhea
B)Hepatotoxicity
C)Renal insufficiency
D)Cataracts

Question 9

Which agent used to treat seborrhea should be applied at bedtime and allowed to remain overnight?

A)sulfacetamide lotion
B)ketoconazole
C)selenium sulfide
D)pyrithione zinc

Question 10

How often should sunscreen be applied?

A)5 minutes before sun exposure and then reapplied 30 minutes to 2 hours after exposure to the sun
B)15 minutes before sun exposure and then reapplied 30 minutes to 2 hours after exposure to the sun
C)5 minutes before sun exposure with no need to reapply if sun protection factor (SPF)is higher than 50
D)15 minutes before sun exposure with no need to reapply if SPF is higher than 50

Question 11

A solution of active ingredients with alcohol as the solvent is known as:

A)Lotion.
B)Tincture.
C)Gel.
D)Paste.

Question 12

What is the most common adverse effect of topical corticosteroid absorption use?

A)Cutaneous atrophy
B)Hyperpigmentation
C)Night blindness
D)Excess hair growth

Question 13

Which fungal infection needs to be treated with oral antifungal therapy instead of initial topical therapy?

A)Tinea unguium
B)Tinea pedis
C)Tinea cruris
D)Tinea capitis

Question 14

When should antiviral medications be started for a patient with herpes zoster?

A)Within 72 hours of the onset of lesions
B)Within 72 hours after the lesions have dried and crusted
C)Within 96 hours of the onset of lesions
D)Within 96 hours after the lesions have dried and crusted

Question 15

What can be done to increase the absorption of moisturizing agents into the skin?

A)Occluding the skin with plastic wrap
B)Washing the skin with alcohol prior to applying the agent
C)Soaking the dressing prior to applying the agent
D)Cooling the skin with ice packs

Question 16

A stage III or IV pressure ulcer can be treated with which agent?

A)Silver sulfadiazine film
B)Wet-to-dry dressing
C)Dry-to-wet dressing
D)Absorptive dressing

Question 17

Which statement regarding oral agents used to treat psoriasis is true?

A)They all should be used in caution with patients who have hepatic dysfunction.
B)They are all contraindicated in patients with a history of malignancy.
C)They all require periodic laboratory monitoring to ensure their safety.
D)Pregnancy should be avoided for at least 3 years with the use of these agents.

Question 18

Which medication used to treat acne has a pregnancy category C rating by the U.S.Food and Drug Administration (FDA)?

A)Tretinoin
B)Benzoyl peroxide
C)Minocycline
D)Salicylic acid

Question 19

Which drug is considered a low-potency corticosteroid?

A)clobetasol propionate 0.05% (Temovate)
B)amcinonide ointment 0.1% (Cyclocort)
C)desonide lotion 0.05% (DesOwen)
D)hydrocortisone cream,ointment and lotion 1% and 2.5% (Hytone)

Question 20

Which statement regarding ultraviolet (UV)A radiation exposure is not true?

A)UVA radiation exposure causes wrinkling.
B)UVA radiation exposure can lead to skin cancer.
C)UVA radiation exposure can penetrate skin less deeply than UVB radiation.
D)UVA radiation is only minimally reduced by some sunscreens.

Question 21

Possible side effects of topical agents such as keratolytics (e.g. ,benzoyl peroxide)used to treat acne include all of the following except:

A)Irritation.
B)Peeling.
C)Dryness.
D)Discoloration of teeth.

Question 22

Which option is not a layer of the epidermis?

A)Stratum corneum
B)Stratum lucidum
C)Stratum granulosum
D)Stratum follicularis

Question 23

Which agent is used "off-label" to treat psoriasis?

A)hydroxyurea
B)methotrexate
C)acitretin
D)cyclosporin A

Question 24

When used in conjunction with epinephrine,what is the maximum dosage of lidocaine that can be used by clinicians to prevent toxicity?

A)4.5 mg/kg
B)7 mg/kg
C)9 mg/kg
D)14 mg/kg

Question 25

A pressure ulcer that exhibits extension through the dermis is classified as:

A)Stage I.
B)Stage II.
C)Stage III.
D)Stage IV.

Question 26

Probenecid,a drug used to treat gout,should be used with caution in patients being treated with what other medication?

A)famciclovir
B)erythromycin
C)benzoyl peroxide
D)mupirocin

Question 27

Fluorinated corticosteroids used in treating eczema should not be used on which part of the body?

A)Hands
B)Face
C)Back
D)Toes

Question 28

The American Academy of Dermatology characterizes mild acne as:

A)Redness of the central area of the face that may or may not include comedones.
B)Few to several papules and pustules,but no nodules.
C)Several papules and pustules and a few nodules.
D)Extensive papules and pustules,along with many nodules.