Deck 12: Drugs Used to Treat Endocrine Gland Disorders

Question 1

If the dose of liotrix is too low,which of the following can occur?

A)Diarrhea
B)Constipation
C)Irritability
D)Hypoglycemia

Answer 1

Constipation

Question 2

What is the onset of action of propylthiouracil (PTU)?

A)10 to 12 hours
B)12 to 24 hours
C)24 to 36 hours
D)36 to 48 hours

Answer 2

24 to 36 hours

Question 3

Levothyroxine sodium is secreted in which of the following?

A)Feces
B)Urine
C)Saliva
D)Sweat

Answer 3

Feces

Question 4

A dose of levothyroxine should be held if the heart rate is which of the following?

A)Above 60 bpm
B)Above 75 bpm
C)Above 80 bpm
D)Above 100 bpm

Question 5

Which of the following is the typical starting dose of levothyroxine sodium?

A)15 mcg
B)30 mcg
C)45 mcg
D)50 mcg

Question 6

The half-life of liothyronine is:

A)1 to 2 days.
B)2 to 3 days.
C)3 to 4 days.
D)4 to 5 days.

Question 7

What is the typical starting does of PTU?

A)50 mg
B)100 mg
C)200 mg
D)300 mg

Question 8

The maximum response of liothyronine (T3)and levothyroxine (T4)combination is seen in:

A)2 to 3 hours.
B)2 to 3 days.
C)2 to 3 weeks.
D)2 to 3 months.

Question 9

Levothyroxine sodium is contraindicated in which of the following scenarios?

A)Patient with new-onset diabetes mellitus
B)Patient with recent hip replacement
C)Patient with a recent myocardial infarction
D)Patient who is obese

Question 10

Which of the following can impair the absorption of liothyronine?

A)Insulin
B)Vitamin K
C)Tricyclic antidepressants
D)Cholestyramine

Question 11

Which of the following is a contraindication for the use of PTU?

A)Pregnancy
B)Recent myocardial infarction
C)Migraine headaches
D)Asthma

Question 12

Which of the following reversible side effects is seen in children when starting liothyronine (T3)and levothyroxine (T4)combination therapy?

A)Weight gain
B)Acne
C)Hair loss
D)Eczema

Question 13

What is the onset of action of methimazole (Tapazole)?

A)One day
B)One week
C)One month
D)Six months

Question 14

Which of the following can increase the absorption of liothyronine?

A)Fasting
B)Malabsorption syndrome
C)Orange juice
D)Milk

Question 15

What is the half-life of PTU?

A)0.5 to 1 hour
B)1.5 to 5 hours
C)4 to 8 hours
D)5 to 10 hours

Question 16

Adequacy of thyroxin therapy can be assessed by Thyroid stimulating hormone (TSH)measurement how long after the dose is started?

A)2 to 3 weeks
B)4 to 6 weeks
C)6 to 8 weeks
D)8 to 10 weeks

Question 17

Which of the following can decrease the absorption of levothyroxine?

A)Milk
B)Carrots
C)Oranges
D)Apples

Question 18

50% to 80% of Synthroid is absorbed by the:

A)Liver.
B)Gastrointestinal (GI)tract.
C)Kidneys.
D)Mucous membranes.

Question 19

Which of the following is a hematologic adverse effect of PTU?

A)Anemia
B)Thrombocytopenia
C)Agranulocytosis
D)Leukocytosis

Question 20

Which of the following is one of the clinical uses of levothyroxine sodium?

A)Decreases basal metabolism
B)Decreases protein synthesis
C)Enhances gluconeogenesis
D)Enhances gastric motility

Question 21

Which of the following is an early sign of an overdose of calcitrol?

A)Metallic taste sensations
B)Photophobia
C)Rhinorrhea
D)Pruritus

Question 22

Vasopressin is used to treat which of the following?

A)Diabetes mellitus
B)Hypothyroidism
C)Diabetes insipidus
D)Factor V Leiden

Question 23

Lypressin is administered:

A)Orally.
B)Transdermally.
C)Intravenously.
D)Intranasally.

Question 24

Which of the following is a short-acting steroid?

A)Betamethasone
B)Cortisone
C)Prednisone
D)Triamcinolone

Question 25

Administering cinacalcet (Sensipar)can increase the levels of which antidepressant if administered together?

A)citalopram
B)fluoxetine
C)amitriptyline
D)bupropion

Question 26

Which of the following should you monitor in patients taking methimazole (Tapazole)?

A)PT/PTT
B)Complete blood cell count
C)Urinalysis
D)Potassium

Question 27

Somatrem (Protropin)is excreted via:

A)Urine.
B)Kidneys.
C)Biliary tract.
D)Saliva.

Question 28

Methimazole (Tapazole)is primarily excreted via:

A)Feces.
B)Biliary tract.
C)GI tract.
D)Urine.

Question 29

Patients taking methimazole (Tapazole)should avoid which of the following?

A)Milk
B)Oranges
C)Seafood
D)Steak

Question 30

What is the mechanism of action of oxytocin?

A)Reduces uterine contractions
B)Stimulates uterine contractions
C)Reduces peristalsis
D)Stimulates peristalsis

Question 31

Which of the following describes the mechanism of action of calcitrol?

A)Decreases calcium and phosphate absorption from the small intestine
B)Decreases secretion of calcium from bone to blood
C)Promotes renal tubule phosphate secretion
D)Acts on bone cells to promote skeletal growth

Question 32

Calcitrol is primarily excreted via:

A)Urine.
B)Kidney.
C)Feces.
D)Large intestines.

Question 33

Prolonged infusion of oxytocin can cause which of the following?

A)Headache
B)Diplopia
C)Fatigue
D)Seizures

Question 34

Which of the following drugs interfere with parathyroid hormone (PTH)secretion?

A)cinacalcet
B)estrogen
C)bisphosphonates
D)selective estrogen-receptor modulators

Question 35

What is one side effect of somatrem (Protropin)?

A)Hepatitis
B)Otitis media
C)Hypotension
D)Fatigue

Question 36

Growth hormone does which of the following?

A)Affects the cartilaginous growth areas of long bones
B)Decreases the number and size of skeletal muscle cells
C)Negatively effects the size of organs
D)Decreases red cell mass through erythropoietin stimulation

Question 37

What is the mechanism of action of desmopressin?

A)Increases reabsorption of water by increasing the permeability of collecting ducts in the kidney,thus decreasing urinary output
B)Decreases reabsorption of water by decreasing the permeability of collecting ducts in the kidney,thus decreasing urinary output
C)Increases reabsorption of water by increasing the permeability of collecting ducts in the kidney,thus increasing urinary output
D)Increases reabsorption of water by decreasing the permeability of collecting ducts in the kidney,thus decreasing urinary output

Question 38

After using octreotide (Sansostatin)for one year,which of the following can a patient develop?

A)Osteonecrosis of the jaw
B)Cholelithiasis
C)Gingivitis
D)Splenomegaly

Question 39

Dosing adjustments of cinacalcet (Sensipar)are based on which of the following levels?

A)Hemoglobin
B)Magnesium
C)Calcium
D)Vitamin D

Question 40

Which of the following is a contraindication to using fludrocortisone (Florinef)?

A)Asthma
B)Obesity
C)Fungal infection
D)Contact dermatitis