Deck 23: Patterns of Gene Inheritance
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Deck 23: Patterns of Gene Inheritance
1
In humans, brown eyes (B) are a simple dominant trait over blue eyes (b). What is the genotype of a brown-eyed woman who has a blue-eyed child?
A) bb
B) Bb
C) BB
D) BBB
E) BbBb
A) bb
B) Bb
C) BB
D) BBB
E) BbBb
B
2
A woman who can roll her tongue is married to a man who cannot. Two of their four children can roll their tongues and two cannot. If T = tongue rolling and t = cannot roll tongue, then what is the genotype of the parents?
A) woman Tt; man Tt
B) woman TT; man tt
C) woman Tt; man TT
D) woman Tt; man tt
E) woman tt; man tt
A) woman Tt; man Tt
B) woman TT; man tt
C) woman Tt; man TT
D) woman Tt; man tt
E) woman tt; man tt
D
3
A pheasant breeder starts with two birds in the P generation, one of which is AA and the other is aa. If he takes two of the birds from the F1 generation and breeds them together, what genotypes can he expect in his F2 offspring?
A) AA and Aa
B) Aa and aa
C) AA, Aa, and aa
D) AA only
E) Aa only
A) AA and Aa
B) Aa and aa
C) AA, Aa, and aa
D) AA only
E) Aa only
C
4
In a testcross, an organism with a dominant phenotype, but unknown genotype, is crossed with an organism that is
A) homozygous dominant.
B) heterozygous.
C) homozygous recessive.
D) heterozygous dominant.
E) monohybrid dominant.
A) homozygous dominant.
B) heterozygous.
C) homozygous recessive.
D) heterozygous dominant.
E) monohybrid dominant.
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5
What genotypic ratio would result from a cross between two individuals who are both heterozygous for a trait?
A) 100% homozygous dominant
B) 100% homozygous recessive
C) 50% homozygous dominant, 50% homozygous recessive
D) 25% homozygous dominant, 50% heterozygous, 25% homozygous recessive
E) 50% homozygous dominant, 50% heterozygous
A) 100% homozygous dominant
B) 100% homozygous recessive
C) 50% homozygous dominant, 50% homozygous recessive
D) 25% homozygous dominant, 50% heterozygous, 25% homozygous recessive
E) 50% homozygous dominant, 50% heterozygous
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6
In which kind of monohybrid cross would you expect to find a phenotypic ratio of 3:1 among the offspring?
A) heterozygous × heterozygous
B) homozygous recessive × homozygous recessive
C) homozygous dominant × homozygous dominant
D) homozygous recessive × homozygous dominant
E) homozygous dominant × heterozygous
A) heterozygous × heterozygous
B) homozygous recessive × homozygous recessive
C) homozygous dominant × homozygous dominant
D) homozygous recessive × homozygous dominant
E) homozygous dominant × heterozygous
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7
In peas, the yellow seed color is dominant (YY or Yy) over the green seed color (yy). You have been given a plant that only produces yellow seeds and need to determine if the plant is YY or Yy. Which of the following crosses would be most effective for determining the genotype of your plant?
A) your plant × a plant that produces only green seeds
B) your plant × another plant with known genotype YY
C) your plant × another plant with known genotype Yy
D) No cross is necessary. You should just plant your yellow seed and see what color flowers it produces.
E) There is no way to determine the genotype of your plant.
A) your plant × a plant that produces only green seeds
B) your plant × another plant with known genotype YY
C) your plant × another plant with known genotype Yy
D) No cross is necessary. You should just plant your yellow seed and see what color flowers it produces.
E) There is no way to determine the genotype of your plant.
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8
The genetic makeup of an individual is also known as their
A) phenotype.
B) loci.
C) genotype.
D) factors.
A) phenotype.
B) loci.
C) genotype.
D) factors.
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9
When crossing organisms with differing genotypes, you can expect your actual results to match the predicted results 100% of the time.
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10
Which of the following is true according to Mendel's law of segregation?
A) Each individual contains two alleles for each trait.
B) Fertilization restores the presence of two alleles.
C) Alleles separate from each other during gamete formation.
D) Each gamete contains one copy of each allele.
E) All of the answer choices are true about Mendel's law of segregation.
A) Each individual contains two alleles for each trait.
B) Fertilization restores the presence of two alleles.
C) Alleles separate from each other during gamete formation.
D) Each gamete contains one copy of each allele.
E) All of the answer choices are true about Mendel's law of segregation.
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11
Due to a recessively inherited trait, some plants fail to produce chlorophyll and therefore are white rather than green. If we locate a pea plant that is heterozygous for this trait, self-pollinate it, harvest the seeds, and then plant the seeds, what are the likely phenotypes of the resulting offspring?
A) 100% green
B) 100% white
C) approximately 1/2 green and 1/2 white
D) approximately 1/4 white and 3/4 green
E) approximately 1/4 green and 3/4 white
A) 100% green
B) 100% white
C) approximately 1/2 green and 1/2 white
D) approximately 1/4 white and 3/4 green
E) approximately 1/4 green and 3/4 white
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12
The ability to roll the edges of the tongue upward in a U-shape is inherited as a dominant allele at a single gene locus. Which of the following genotypes would produce an individual that can roll their tongue?
A) TT only
B) Tt only
C) tt only
D) TT or Tt
E) Tt or tt
A) TT only
B) Tt only
C) tt only
D) TT or Tt
E) Tt or tt
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13
For Mendel's law of segregation to occur, the alleles must be
A) at different loci on the same chromosome.
B) at the same loci on the same chromosome.
C) on a nonhomologous pair of chromosomes.
D) on a homologous pair of chromosome at the same loci.
E) on different loci on different chromosomes.
A) at different loci on the same chromosome.
B) at the same loci on the same chromosome.
C) on a nonhomologous pair of chromosomes.
D) on a homologous pair of chromosome at the same loci.
E) on different loci on different chromosomes.
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14
Tay-Sachs is a recessive genetic disease in humans. If one parent is homozygous normal and the other is a carrier (heterozygous), what are the chances that their child will have this disease?
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
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15
If T = tall and t = short in plants, the genotype of a short plant would be
A) either TT or Tt.
B) either Tt or tt.
C) only TT.
D) only tt.
E) TT, Tt, or tt.
A) either TT or Tt.
B) either Tt or tt.
C) only TT.
D) only tt.
E) TT, Tt, or tt.
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16
In humans, widow's peak (W) is dominant over straight hairline (w). If a heterozygous male marries a female with a straight hairline, what percent of their children can be expected to have widow's peak?
A) 0%
B) 25%
C) 50%
D) 100%
E) The answer cannot be determined by the information given.
A) 0%
B) 25%
C) 50%
D) 100%
E) The answer cannot be determined by the information given.
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17
The alternate forms of a gene for the same trait are known as
A) alleles.
B) phenotypes.
C) genotypes.
D) codominants.
E) incomplete dominants.
A) alleles.
B) phenotypes.
C) genotypes.
D) codominants.
E) incomplete dominants.
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18
Mendel carried out most of his research with
A) livestock.
B) pea plants.
C) guinea pigs.
D) fruit flies.
E) bacteria.
A) livestock.
B) pea plants.
C) guinea pigs.
D) fruit flies.
E) bacteria.
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19
Mendel's law of segregation implies that the two members of an allele pair
A) are distributed to separate gametes.
B) are distributed to the same gamete.
C) are assorted dependently.
D) are segregated pairwise.
E) must always code for the identical trait or feature.
A) are distributed to separate gametes.
B) are distributed to the same gamete.
C) are assorted dependently.
D) are segregated pairwise.
E) must always code for the identical trait or feature.
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20
An individual's physical characteristics, or microscopic and metabolic characteristics, are known as their
A) phenotype.
B) genotype.
C) alleles.
D) traits.
E) pedigree.
A) phenotype.
B) genotype.
C) alleles.
D) traits.
E) pedigree.
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21
In humans, assume straight hairline is recessive to widow's peak. A woman with a straight hairline is married to a man with a widow's peak whose mother had a straight hairline. What are the chances of the couple having a child with a straight hairline?
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
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22
In guinea pigs, B = black, b = brown, S = short hair, s = long hair. A guinea pig heterozygous for both traits is mated with a brown, short-haired guinea pig whose mother had long hair. What phenotypic ratio is expected in the offspring?
A) 9 black long hair, 3 black short hair, 3 brown long hair, 1 brown short hair.
B) 9 black short hair, 6 black long hair, 3 brown long hair, 1 black short hair.
C) 6 black short hair, 1 black long hair, 6 brown short hair, 2 brown long hair.
D) 6 brown short hair, 6 black long hair, 2 brown long hair, 2 black short hair.
E) 1 black short hair, 1 black long hair, 1 brown short hair, 1 brown long hair.
A) 9 black long hair, 3 black short hair, 3 brown long hair, 1 brown short hair.
B) 9 black short hair, 6 black long hair, 3 brown long hair, 1 black short hair.
C) 6 black short hair, 1 black long hair, 6 brown short hair, 2 brown long hair.
D) 6 brown short hair, 6 black long hair, 2 brown long hair, 2 black short hair.
E) 1 black short hair, 1 black long hair, 1 brown short hair, 1 brown long hair.
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23
If the probability in any pregnancy of having a boy is 50%, then what is the probability of having 3 boys in a row?
A) 3/4
B) 1/4
C) 1/8
D) 1/2
E) 3/16
A) 3/4
B) 1/4
C) 1/8
D) 1/2
E) 3/16
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24
A blue-eyed, left-handed woman marries a brown-eyed, right-handed man who is heterozygous for both of his traits. If blue eyes and left-handedness are recessive, how many different phenotypes are possible in their children?
A) one
B) two
C) three
D) four
E) five
A) one
B) two
C) three
D) four
E) five
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25
Two parents heterozygous for cystic fibrosis have a child with the disease. The parents are expecting a second child. What is the probability that the second child will also have cystic fibrosis?
A) 100% probability
B) 75% probability
C) 50% probability
D) 25% probability
E) 0% probability
A) 100% probability
B) 75% probability
C) 50% probability
D) 25% probability
E) 0% probability
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26
When pairs of factors separate independently of other pairs of factors, this is known as
A) the law of segregation.
B) the law of independent assortment.
C) the law of dominance.
D) multiple alleles.
E) codominance.
A) the law of segregation.
B) the law of independent assortment.
C) the law of dominance.
D) multiple alleles.
E) codominance.
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27
Albinism is inherited as a recessive trait. An albino woman is married to a man with normal coloring and their first child is an albino. What was the genotype of the man?
A) homozygous dominant
B) heterozygous
C) homozygous recessive
D) incompletely dominant
E) sex-linked recessive
A) homozygous dominant
B) heterozygous
C) homozygous recessive
D) incompletely dominant
E) sex-linked recessive
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28
Both parents are heterozygous for Tay-Sachs disease (an autosomal recessive disorder). Three children in a row were born with Tay-Sachs disease. What is the chance that a fourth child will have Tay-Sachs disease?
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
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29
If the genotype of an organism is YySsTt, then yST would represent
A) the genotype of the offspring.
B) a possible phenotype of the offspring.
C) a gamete of the parent.
D) a possible zygote.
E) the P generation.
A) the genotype of the offspring.
B) a possible phenotype of the offspring.
C) a gamete of the parent.
D) a possible zygote.
E) the P generation.
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30
Which of the following crosses will yield only homozygous recessive offspring?
A) RRYY × RRYY
B) RRYY × rryy
C) RrYy × rryy
D) rryy × rryy
E) RrYy × RrYy
A) RRYY × RRYY
B) RRYY × rryy
C) RrYy × rryy
D) rryy × rryy
E) RrYy × RrYy
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31
Two parents with widow's peak and short fingers have a child with a continuous hairline and long fingers. What are the genotypes of the two parents? (W = widow's peak; S = short fingers)
A) WWSS × wwss
B) wwss × WWSS
C) WWss × WWss
D) WwSs × WwSs
E) WwSs × wwss
A) WWSS × wwss
B) wwss × WWSS
C) WWss × WWss
D) WwSs × WwSs
E) WwSs × wwss
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32
A cross that involves two traits is called a
A) monohybrid cross.
B) dihybrid cross.
C) Punnett square.
D) testcross.
E) trihybrid cross.
A) monohybrid cross.
B) dihybrid cross.
C) Punnett square.
D) testcross.
E) trihybrid cross.
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33
In guinea pigs, B = black, b = brown, S = short hair, s = long hair. A black, short-haired animal who is homozygous for both traits, reproduces with a brown, long-haired animal. What is the expected phenotypic ratio of the offspring?
A) 1 black short hair, 1 black long hair, 1 brown short hair, 1 brown long hair
B) 3 black short hair, 1 brown long hair, 3 black long hair, 1 brown short hair
C) 9 black short hair, 3 black long hair, 3 brown long hair, 1 brown short hair
D) 100% black short hair
E) 1 black short hair, 1 brown short hair
A) 1 black short hair, 1 black long hair, 1 brown short hair, 1 brown long hair
B) 3 black short hair, 1 brown long hair, 3 black long hair, 1 brown short hair
C) 9 black short hair, 3 black long hair, 3 brown long hair, 1 brown short hair
D) 100% black short hair
E) 1 black short hair, 1 brown short hair
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34
An individual with a dominant phenotype is crossed with an individual with a recessive phenotype. Five out of nine offspring show the dominant phenotype. What is the genotype of the dominant parent?
A) homozygous dominant
B) heterozygous
C) homozygous recessive
D) either homozyous dominant or heterozygous
E) There is not enough information to determine the genotype of the dominant parent.
A) homozygous dominant
B) heterozygous
C) homozygous recessive
D) either homozyous dominant or heterozygous
E) There is not enough information to determine the genotype of the dominant parent.
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35
Unattached earlobes (EE or Ee) are dominant over attached earlobes (ee). A couple has unattached earlobes. Both notice that one of their parents on both sides have attached earlobes (ee). Therefore, they correctly assume that they are carriers for attached earlobes (Ee). If the couple proceeds to have four children, then
A) they can be certain that three will be heterozygous and one homozygous recessive.
B) if the first three are heterozygous, the fourth must be homozygous recessive.
C) the children must repeat the grandparents' genotype (Ee).
D) all children must have unattached earlobes since both parents possess the dominant gene for it.
E) two heterozygous, one homozygous dominant, and one homozygous recessive is a likely outcome, but all genotype ratios are possible.
A) they can be certain that three will be heterozygous and one homozygous recessive.
B) if the first three are heterozygous, the fourth must be homozygous recessive.
C) the children must repeat the grandparents' genotype (Ee).
D) all children must have unattached earlobes since both parents possess the dominant gene for it.
E) two heterozygous, one homozygous dominant, and one homozygous recessive is a likely outcome, but all genotype ratios are possible.
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36
In cattle, consider that the lack of horns is dominant to the presence of horns. A bull without horns is crossed with a horned cow. All eight offspring lack horns. The bull is most likely
A) homozygous dominant.
B) homozygous recessive.
C) heterozygous.
D) sex-lined recessive.
E) heterozygous recessive.
A) homozygous dominant.
B) homozygous recessive.
C) heterozygous.
D) sex-lined recessive.
E) heterozygous recessive.
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37
Which of the following crosses will yield four phenotypes in a ratio of 9:3:3:1?
A) RRYY × RRYY
B) RRYY × rryy
C) RrYy × RrYy
D) RrYy × rryy
E) rryy × rryy
A) RRYY × RRYY
B) RRYY × rryy
C) RrYy × RrYy
D) RrYy × rryy
E) rryy × rryy
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38
Which of the following crosses will yield four phenotypes in the 1:1:1:1 ratio?
A) RRYY × RRYY
B) RRYY × rryy
C) RrYy × RrYy
D) RrYy × rryy
E) rryy × rryy
A) RRYY × RRYY
B) RRYY × rryy
C) RrYy × RrYy
D) RrYy × rryy
E) rryy × rryy
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39
In 1940, two researchers named Weiner and Landsteiner discovered that about 85% of the human population sampled possessed a blood cell protein called the Rh factor. The presence of Rh factor was labeled Rh positive (Rh+) and was found to be dominant over the absence of the blood factor (Rh-). Rh factor is inherited in a typical Mendelian pattern. Based on this information, one could predict that two Rh+ parents could never have an Rh- child.
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40
Which of the following would be considered a heterozygous dihybrid genotype?
A) Ww
B) sS
C) WWSs
D) WWss
E) WwSs
A) Ww
B) sS
C) WWSs
D) WWss
E) WwSs
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41
In humans, aniridia, a type of blindness, is due to a dominant allele A. Migraine headaches are due to another dominant allele M. If a man who suffers from both conditions (AaMm) marries a woman who suffers from both (AaMm), what are the chances of an offspring expressing both traits?
A) 9/16
B) 3/16
C) 1/2
D) 1/16
E) 4/16
A) 9/16
B) 3/16
C) 1/2
D) 1/16
E) 4/16
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42
Consider skin color is regulated by three genes: A, B, and C. All recessive alleles would be 0 or white on the color scale. All dominant alleles would be 6 or black on the color scale. What color is a person with AAbbCc genotype?
A) 6 or black
B) 5 or dark
C) 3 or medium brown
D) 2 or light
E) 0 or white
A) 6 or black
B) 5 or dark
C) 3 or medium brown
D) 2 or light
E) 0 or white
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43
In which kind of cross could you expect to find ratios of 1:1:1:1 among the offspring?
A) monohybrid cross
B) dihybrid cross
C) one-trait testcross
D) two-trait testcross
E) No cross will yield offspring in 1:1:1:1 ratios.
A) monohybrid cross
B) dihybrid cross
C) one-trait testcross
D) two-trait testcross
E) No cross will yield offspring in 1:1:1:1 ratios.
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44
If one parent has type B blood and the other has type AB, what type might the child have?
A) A or O only
B) B or O only
C) A or B only
D) A, B, AB only
E) A, B, O, or AB
A) A or O only
B) B or O only
C) A or B only
D) A, B, AB only
E) A, B, O, or AB
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45
Hydrangeas are flowering plants with large, showy blooms. When the plant is grown in alkaline soil, the flowers are pink. When the plant is grown in acidic soil, the flowers turn blue. This change is phenotype is an example of
A) codominance.
B) incomplete dominance.
C) environmental influence.
D) polygenic inheritance.
E) epistatic interaction.
A) codominance.
B) incomplete dominance.
C) environmental influence.
D) polygenic inheritance.
E) epistatic interaction.
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46
You have two true-breeding rose bushes, one with red flowers and one with white flowers. A cross between these two roses yields a rose bush with two-color flowers. Each flower is both red and white. This is an example of
A) codominance.
B) incomplete dominance.
C) environmental effects.
D) polygenic inheritance.
E) epistatic interaction.
A) codominance.
B) incomplete dominance.
C) environmental effects.
D) polygenic inheritance.
E) epistatic interaction.
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47
When two or more sets of alleles affect the same trait, it is termed
A) a single-trait cross.
B) a double-trait cross.
C) codominant.
D) incomplete dominance.
E) polygenic inheritance.
A) a single-trait cross.
B) a double-trait cross.
C) codominant.
D) incomplete dominance.
E) polygenic inheritance.
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48
In four o'clock flowers, R = red, r = white, and Rr = pink. If two hybrids are crossed, what are the chances that an offspring will have pink flowers?
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
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49
The inheritance of blood types in humans can be explained by
A) simple Mendelian genetics (one gene pair).
B) linked genes.
C) simple dominance.
D) multiple alleles.
E) polygenic inheritance.
A) simple Mendelian genetics (one gene pair).
B) linked genes.
C) simple dominance.
D) multiple alleles.
E) polygenic inheritance.
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50
In the determination of eye color, the HERC2 gene overrides the instructions of the OCA2 gene. If individuals are homozygous for a recessive allele of HERC2, they will have blue eyes regardless of the genotype associated with OCA2. This is an example of
A) epistatic interactions.
B) a two-trait cross.
C) incomplete dominance.
D) codominance.
E) homologous chromosomes.
A) epistatic interactions.
B) a two-trait cross.
C) incomplete dominance.
D) codominance.
E) homologous chromosomes.
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51
A man with blood type O would not be able to father a child with
A) blood type A.
B) blood type B.
C) blood type AB.
D) blood type O.
E) any blood type.
A) blood type A.
B) blood type B.
C) blood type AB.
D) blood type O.
E) any blood type.
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52
Given that curly hair (WW) and straight hair (ww) exhibit incomplete dominance, what are the chances that two individuals with wavy hair will have a curly-haired child?
A) none
B) 25%
C) 50%
D) 75%
E) 100%
A) none
B) 25%
C) 50%
D) 75%
E) 100%
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53
In horses, black coat (B) is dominant over brown coat (b), and being a trotter (T) is dominant over being a pacer (t). A black horse who is a pacer is crossed with a brown horse who is a trotter. The offspring is a brown pacer. What is the genotype of the brown trotter parent?
A) BBTT
B) BbTt
C) Bbtt
D) bbTt
E) bbtt
A) BBTT
B) BbTt
C) Bbtt
D) bbTt
E) bbtt
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54
You have two true-breeding rose bushes, one with red flowers and one with white flowers. A cross between these two roses yields a bush with pink flowers. The pink flower color is an example of
A) codominance.
B) incomplete dominance.
C) environmental effects.
D) polygenic inheritance.
E) epistatic interaction.
A) codominance.
B) incomplete dominance.
C) environmental effects.
D) polygenic inheritance.
E) epistatic interaction.
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55
Which of the following produces an intermediate phenotype?
A) codominance
B) sex-linked inheritance
C) polygenic inheritance
D) simple Mendelian inheritance
E) incomplete dominance
A) codominance
B) sex-linked inheritance
C) polygenic inheritance
D) simple Mendelian inheritance
E) incomplete dominance
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56
Traits that are controlled by several sets or pairs of alleles, such as skin color and height in humans, are the result of what form of inheritance?
A) polygenic
B) incomplete dominance
C) multiple allele systems
D) simple Mendelian inheritance
E) codominance
A) polygenic
B) incomplete dominance
C) multiple allele systems
D) simple Mendelian inheritance
E) codominance
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57
Mr. X has been accused by Miss Z of fathering her child. The child's blood type is AB and Miss Z's blood type is A. Which blood type(s) would eliminate Mr. X as a possible father of the child?
A) only A
B) only B
C) AB
D) only O
E) either A or O
A) only A
B) only B
C) AB
D) only O
E) either A or O
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58
A cross is made between two parents with genotypes AaBB and aabb. If there are 32 offspring, how many of them would be expected to exhibit both dominant characteristics?
A) 32
B) 24
C) 16
D) 8
E) 0
A) 32
B) 24
C) 16
D) 8
E) 0
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59
The leaves of a maple tree vary in size depending on the location of the leaves on the tree. Those growing at the outer region of the tree tend to be smaller than those growing closer to the trunk of the tree. This allows leaves that are growing in the shade to have a larger surface area. This is an example of
A) response to environmental factors.
B) epistatic interactions.
C) codominance.
D) Mendelian inheritance.
E) incomplete dominance.
A) response to environmental factors.
B) epistatic interactions.
C) codominance.
D) Mendelian inheritance.
E) incomplete dominance.
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60
Huntington disease is an autosomal dominant disorder that leads to progressive degeneration of brain cells. There is no effective treatment for the disorder and individuals usually die in their 40s or 50s, 10 to 15 years after the onset of symptoms. Which of these statements about Huntington disease is true?
A) As an autosomal dominant disease, Huntington disease is expressed only if both parents carry the trait.
B) Huntington disease usually skips a generation.
C) Researchers have located the gene for Huntington disease on chromosome 9.
D) Huntington disease usually appears during the teenage years.
E) Huntington disease is caused by a mutated copy of the gene for a protein called huntingtin.
A) As an autosomal dominant disease, Huntington disease is expressed only if both parents carry the trait.
B) Huntington disease usually skips a generation.
C) Researchers have located the gene for Huntington disease on chromosome 9.
D) Huntington disease usually appears during the teenage years.
E) Huntington disease is caused by a mutated copy of the gene for a protein called huntingtin.
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61
What genetic disorder is associated with the lack of an enzyme necessary for the normal metabolism of the amino acid phenylalanine?
A) phenylketonuria (PKU)
B) Marfan syndrome
C) Huntington disease
D) sickle cell disease
E) cystic fibrosis (CF)
A) phenylketonuria (PKU)
B) Marfan syndrome
C) Huntington disease
D) sickle cell disease
E) cystic fibrosis (CF)
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62
Which of the following is an autosomal dominant disorder?
A) Marfan syndrome
B) Tay-Sachs
C) sickle cell disease
D) cystic fibrosis (CF)
E) phenylketonuria (PKU)
A) Marfan syndrome
B) Tay-Sachs
C) sickle cell disease
D) cystic fibrosis (CF)
E) phenylketonuria (PKU)
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63
In humans, an individual who has wavy hair is a heterozygote with one curly hair allele and one straight hair allele. Indicate the phenotypic and genotypic ratios expected for the offspring from a straight-haired man and a wavy-haired woman.
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64
In the following pedigree, what does the colored circle indicate? 
A) an affected father
B) an affected mother
C) an affected daughter
D) an affected son
E) an affected cousin

A) an affected father
B) an affected mother
C) an affected daughter
D) an affected son
E) an affected cousin
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65
Which allele combination represents a recessive monohybrid trait?
A) aa
B) Aa
C) AA
D) ab
E) Ab
A) aa
B) Aa
C) AA
D) ab
E) Ab
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66
In the human population, short fingers are dominant over long fingers. Indicate the genotypic and phenotypic ratios if a heterozygous short-fingered female reproduces with a long-fingered male.
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67
How many alleles are required to express a monohybrid trait?
A) 2
B) 1
C) 3
D) 5
E) 4
A) 2
B) 1
C) 3
D) 5
E) 4
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68
What pattern of inheritance is shown in the following pedigree? What is the probability that the affected son in generation III will pass the trait on to his children? 
A) autosomal recessive; 25%
B) autosomal recessive; 50%
C) autosomal dominant; 25%
D) autosomal dominant; 50%
E) autosomal dominant; 100%

A) autosomal recessive; 25%
B) autosomal recessive; 50%
C) autosomal dominant; 25%
D) autosomal dominant; 50%
E) autosomal dominant; 100%
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69
Which genetic disorder is associated with a defect in the elastic connective tissue protein called fibrillin?
A) Marfan syndrome
B) Huntington disease
C) sickle cell disease
D) phenylketonuria (PKU)
E) cystic fibrosis (CF)
A) Marfan syndrome
B) Huntington disease
C) sickle cell disease
D) phenylketonuria (PKU)
E) cystic fibrosis (CF)
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70
Which genetic disorder is associated with an irregular shape of the red blood cells?
A) sickle cell disease
B) Marfan syndrome
C) Huntington disease
D) phenylketonuria (PKU)
E) cystic fibrosis (CF)
A) sickle cell disease
B) Marfan syndrome
C) Huntington disease
D) phenylketonuria (PKU)
E) cystic fibrosis (CF)
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71
When investigators try to determine what percentage of various human traits is due to nature (inheritance) and what percentage is due to nurture (the environment), scientists often examine
A) siblings that share only one parent and were separated at birth.
B) non-identical siblings that were separated at birth.
C) identical human twins that were separated at birth.
D) adopted siblings that have been separated due to divorce.
E) unrelated children who have been adopted by the same family and grew up together.
A) siblings that share only one parent and were separated at birth.
B) non-identical siblings that were separated at birth.
C) identical human twins that were separated at birth.
D) adopted siblings that have been separated due to divorce.
E) unrelated children who have been adopted by the same family and grew up together.
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72
Indicate the genotypic and phenotypic ratios that you could expect if an individual who is heterozygous for Huntington disease has children with a normal individual.
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73
In the following pedigree, the inherited condition is due to an autosomal dominant allele.


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