Deck 9: Leukopoiesis and Leukopoietic Function

Question 1

Monocytes recognize foreign antigens and present them to which of the following cells?

A)B cells
B)T cells
C)Neutrophils
D)NK cells

Answer 1

B

Question 2

The "marginating pool" of neutrophils is located:

A)In the kidneys
B)In the tissue
C)Next to marrow sinuses
D)On the blood vessel walls

Answer 2

D

Question 3

The spleen harbors approximately ___ of the white blood cell population

A)one-fourth
B)one-half
C)one-third
D)three-fourths

Answer 3

A

Question 4

At present, most lymphocyte subpopulations are recognized by their CD markers. CD refers to:

A)Codon designation
B)Cluster designation
C)Cytoplasmic designation
D)Cytokine designation

Question 5

The plasma cell is responsible for:

A)Humoral immunity
B)Cell-mediated immunity
C)Tumor suppression
D)Delayed hypersensitivity

Question 6

An adult has a total white blood cell count of 4.0 $\times$ 10⁹/L.The differential count is as follows: Segmented neutrophils 25%
Lymphocytes 65%
Bands 5%
Monocytes 5%
If the normal values for absolute lymphocyte count are 1.2 to 3.4 $\times$ 10⁹/L, which of the following is true?

A)The absolute number of lymphocytes is low.
B)There is an absolute lymphocytosis.
C)There is a relative lymphocytosis.
D)There is an absolute and a relative lymphocytosis.

Question 7

The CBC results for a 3-month-old child are as follows: WBC 9.5 $\times$ 10⁹/L Differential
RBC 3.4 $\times$ 10¹²/L Segmented neutrophils 25%
Hgb 6.7 g/dL Lymphocytes 75%
Hct 25%
The absolute lymphocyte count in this patient would be:

A)1.2 $\times$ 10⁹/L
B)2.4 $\times$ 10^9/L
C)7.1 $\times$ 10⁹/L
D)7.5 $\times$ 10⁹/L

Question 8

Lymphocyte concentrations in peripheral blood are greatest during what age interval?

A)Immediately after birth
B)Older adult (40 to 70 years)
C)Young adult (16 to 40 years)
D)Young child (1 to 4 years)

Question 9

There are ___ maturation stages in the neutrophil.

A)five
B)four
C)three
D)six

Question 10

The amount of time a granulocyte spends in the circulation before migrating into the tissues is normally:

A)8 hours
B)48 hours
C)5 days
D)20 days

Question 11

All of the following are features of the lymphatic system except:

A)Stimulation of the kidney by EPO
B)Blood filtration
C)Antibody generation
D)Lymphopoiesis

Question 12

Mature neutrophils have large, evenly sized, bright orange granules in their cytoplasm.

Question 13

The absolute WBC count refers to the percentage of a particular cell counted from the 100 WBC differential.

Question 14

Which of the following CD markers are more appropriately associated with the myelocyte?

A)CD4, CD8
B)CD33, CD13, CD14
C)CD45, CD33, CD13
D)CD19, CD22

Question 15

The myeloid stem cell produces cell lines that end in the production of granulocytes, monocytes, platelets, and red blood cells.

Question 16

The primary function of lymphocytes is immunologic.

Question 17

The initial appearance of specific granulation in the granulocytic series is predominantly seen in the:

A)Promyelocyte
B)Metamyelocyte
C)Myelocyte
D)Eosinophil

Question 18

One of the primary glands responsible for lymphocyte origination in the infant is the:

A)Thymus
B)Adrenal
C)Thyroid
D)Pituitary

Question 19

The N:C ratio in a myeloblast is:

A)2:1
B)4:1
C)3:1
D)5:1

Question 20

Lymphocyte production differs from myeloid cell production in that there are two major sites of cellular production.

Question 21

It is possible for a patient to have a relatively high lymphocyte count, but with a low white blood cell count, the absolute lymphocyte count may be normal.

Question 22

NK cells are unique in that they contribute to immunity without the needed aid of T or B cells.