Deck 6: Medications From Powders and Crystals: Oral and Intramuscular

Question 1

Ordered: Cipro 400 mg IV for a urinary tract infection. Infuse in 90 minutes.
Available: Cipro (ciprofloxacin) 400 mg in 40 mL of sterile 1% solution
Directions: Further dilute in 200 mL of D₅W.
a. How many drops per minute will you set the IV device to infuse using a gravity tubing at 20 drops per mL?
b. How many mL per hour will you set the electronic infusion device?

Answer 1

a. Use the drop rate formula: drop/time *volume = drops per min $\frac{20}{9} \times \frac{240 \mathrm{~mL}}{1}=\frac{400}{9}=53.3=53 \text { drops per minute }$
b. 160 mL
Know Want to know
240 mL : 90 min :: x mL : 60 min
3x = 8 *60 = 480
3x = 480
x = 160 mL per hour
Proof: 80 * 60 = 480
3* 160 = 480

Question 2

Ordered: Tagamet 200 mg IV every 12 hours for a duodenal ulcer
Available: Tagamet multidose vial with 300 mg per 2 mL
Directions: Dilute each dose with 50 mL of D₅W to infuse in 30 minutes.
a. How many mL of Tagamet will you need?
b. How many mL per hour will you set the electronic infusion device to infuse?

Answer 2

a. 1.33 mL
Know Want to know
150 1
300 mg : 2 mL :: 200 mg : x mL
150x = 1 * 200 = 200
150x = 200
x = 1.33 mL
Proof: 2 * 200 = 400
300 *1.33 = 399
b. 100 mL
Know Want to know
5 3
50 mL : 30 min :: x mL : 60 min
3x = 5 * 60 = 300
3x = 300
x = 100 mL per hour
Proof: 5 * 60 = 300
3 * 100 = 300

Question 3

Ordered: Principen 200 mg po q6h
Available: Principen (ampicillin) for oral suspension
Directions: Add 72 mL of water. Shake well to make 100 mL. Each 5 mL yields 125 mg of ampicillin.
How many milliliters will you give?

Answer 3

8 mL
Have Want to Have
5 mL : 125 mg :: x mL : 200 mg
125 x = 5 *200 = 1000 x = 8 mL
Proof: 5 *200 = 1000
125 * 8 = 1000

Question 4

Ordered: Oxacillin 250 mg IV every 8 hours for 4 doses for a respiratory tract infection. Infuse in 150 mL of D₅W in 50 minutes.
Available: Oxacillin sodium 1 gram
Directions: Add 5.7 mL Sterile Water for Injection. Each 1.5 mL contains 250 mg of oxacillin.
a. How many mL per hour will you set the gravity infusion set with 15 drops per minute?
b. How many mL per hour will you set the electronic infusion device to infuse?

Question 5

Ordered: 40 mEq potassium chloride in 200 mL of D₅W to infuse in 90 minutes for potassium depletion
Available: 20 mL single-dose vial for IV use. Each mL contains 2 mEq of potassium chloride.
a. How many mL of medication will you need to inject into 200 mL of D₅W for infusion?
b. How many mL per hour will you set the electronic infusion device to infuse?

Question 6

Ordered: Doxycycline (Vibramycin) 100 mg IV every 12 hours for gonorrhea
Available: Vibramycin vial with powder to make 100 mg of medication
Directions: Add 8 mL of diluent to make 100 mg of Vibramycin. Further dilute in 150 mL of D₅W to infuse in 50 minutes.
How many mL per hour will you set the IV infusion device to infuse?

Question 7

Ordered: Ranitidine (Zantac) 50 mg IV every 8 hours for gastric ulcers
Available: Zantac injection (ranitidine hydrochloride) 50 mg in 50 mL 0.45% sodium chloride
Directions: Infuse in 20 minutes
How many mL per hour will you set the IV infusion device to infuse?

Question 8

Ordered: Maxipime 500 mg IV every 8 hours for otitis media
Available: Maxipime 1 g
Directions: Add 8.7 mL of diluents to yield 10mL of drug solution. Further dilute dose in 100 mL of D₅W to infuse in 40 minutes.
How many mL per hour will you set the IV infusion device to infuse?

Question 9

Ordered: Piperacillin sodium 2 gram IV every 8 hours for a pelvic infection
Available: Piperacillin 4 gram vial in powdered form
Directions: Add 7.8 mL of diluents to yield 10 mL of drug solution. Dilute the dose in 200 mL of D₅W to infuse in 90 minutes.
How many mL per hour will you set the infusion device to infuse?

Question 10

Ordered: 500,000 units Pfizerpen IM q6h
Available: Pfizerpen 1 million units for reconstitution
Directions for mixing: Add 18.2 mL diluent to yield 250,000 units per mL or add 3 mL diluent to yield 1,000,000 units per mL.
How many milliliters will you give if you use 18.2 mL of diluent?