Deck 24: The Urinary System

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Question
Which portion of the renal tubule has a brush border created by the presence of many microvilli?

A)distal tubule
B)descending limb of the nephron loop (loop of Henle)
C)proximal tubule
D)ascending limb of the nephron loop (loop of Henle)
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Question
What increases the permeability of the glomerulus by making the capillaries "leaky"?

A)microvilli
B)desmosomes
C)fenestrations
D)tight junctions
Question
The portion of the renal tubule through which filtrate initially flows is known as the:

A)collecting duct.
B)nephron loop (loop of Henle).
C)distal tubule.
D)proximal tubule.
Question
Identify the structure marked as "3."

A)distal tubule
B)renal corpuscle
C)proximal tubule
D)collecting duct
Question
What are the two main divisions of the nephron?

A)renal cortex and renal medulla
B)renal pyramids and renal columns
C)renal corpuscle and renal tubule
D)glomerulus and peritubular capillaries
Question
What external covering protects the kidney from physical shock?

A)renal pelvis
B)renal capsule
C)renal fascia
D)adipose capsule
Question
The functional units of the kidneys are:

A)renal sinuses.
B)nephrons.
C)renal pyramids.
D)glomeruli.
Question
Which of the following is NOT a major function of the kidneys?

A)regulation of blood volume and blood pressure
B)hematopoiesis
C)regulation of acid-base balance
D)removal of metabolic wastes
Question
Urine drains from a major calyx into:

A)the renal pelvis.
B)the renal tubule.
C)a papilla.
D)a minor calyx.
Question
A glomerulus is:

A)the source of erythropoietin.
B)attached to the collecting duct.
C)a set of capillaries within the renal corpuscle.
D)a hairpin loop segment of the renal tubule.
Question
Where does blood in the arcuate artery travel next on its journey toward the glomerulus?

A)interlobar artery
B)segmental artery
C)renal artery
D)interlobular (cortical radiate)artery
Question
Place these vessels in the correct order as blood flows into and through the kidney. 1.afferent arteriole
2)arcuate artery
3)efferent arteriole
4)glomerulus
5)interlobar artery
6)interlobular (cortical radiate)artery
7)renal artery
8)segmental artery

A)7,8,6,2,5,1,5,3
B)7,5,8,6,2,4,3,1
C)7,8,5,2,6,1,4,3
D)7,8,2,5,6,3,4,1
Question
Erythropoietin is produced by the kidneys to:

A)regulate red blood cell production by the bone marrow.
B)regulate blood solute concentration.
C)conserve or eliminate hydrogen and bicarbonate ions.
D)regulate removal of metabolic wastes.
Question
Which of the following is the capillary bed fed by the afferent arteriole and drained by the efferent arteriole?

A)peritubular capillaries
B)macula densa cells
C)vasa recta
D)glomerulus
Question
In which kidney region are the renal pyramids located?

A)renal sinus
B)renal cortex
C)renal medulla
D)renal pelvis
Question
Urine is transported from kidney to the urinary bladder by the:

A)aorta.
B)urethra.
C)ureter.
D)inferior vena cava.
Question
The right kidney sits to the left kidney due to the position of the liver.

A)posterior
B)inferior
C)superior
D)medial
Question
The indentation on the medial surface of the kidney is the:

A)pyramid.
B)calyx.
C)hilum.
D)pelvis.
Question
Which vessel is present in the arterial pathway but missing from the venous pathway?

A)interlobar
B)arcuate
C)interlobular (cortical radiate)
D)segmental
Question
What are the three main regions of the kidney?

A)renal pelvis,renal sinus,renal fascia
B)renal sinus,renal medulla,renal cortex
C)renal pelvis,renal medulla,renal cortex
D)renal sinus,renal pelvis,renal cortex
Question
Glomerular colloid osmotic pressure (GCOP)is created by:

A)proteins such as albumin in the blood.
B)fluids in the blood plasma.
C)systemic blood pressure.
D)filtrate in the capsular space.
Question
The myogenic mechanism acts to restore the glomerular filtration rate (GFR)by changing:

A)blood pH.
B)tubular secretion of metabolic wastes.
C)vessel diameter.
D)blood pressure.
Question
What is the normal value for the glomerular filtration rate (GFR)in mL/min?

A)275
B)125
C)75
D)500
Question
What should NOT be found in filtrate?

A)plasma proteins
B)acids and bases
C)metabolic wastes
D)water and electrolytes
Question
Items reclaimed during tubular reabsorption are returned to the:

A)minor calyx.
B)renal pelvis.
C)collecting system.
D)blood.
Question
The glomerular filtration rate is defined as:

A)the amount of filtrate formed by both kidneys in one minute.
B)the amount of filtrate that is reabsorbed during a 24-hour period.
C)the rate at which the kidneys remove a substance from the blood.
D)the percent of blood plasma that passes through the filtration membrane.
Question
What do the macula densa cells regulate in their role as part of the tubuloglomerular feedback loop?

A)changes in renal clearance
B)changes in glomerular hydrostatic pressure (GHP)
C)changes in blood pH
D)changes in the glomerular colloid osmotic pressure (GCOP)
Question
Podocytes in fenestrated glomerular capillaries prevent the filtration of large molecules such as:

A)albumin.
B)nitrogenous wastes.
C)amino acids.
D)glucose.
Question
Which of the following is NOT a true statement about the cortical nephrons?

A)Cortical nephrons are wrapped by the vasa recta.
B)Cortical nephrons have a short nephron loop (loop of Henle).
C)The renal corpuscle of a cortical nephron sits in the outer renal cortex.
D)Cortical nephrons are the most numerous type of nephron in the kidneys.
Question
The process of filtration occurs in the:

A)collecting duct.
B)distal tubule.
C)proximal tubule.
D)renal corpuscle.
Question
What is net filtration pressure (NFP)in the glomerular capillaries,in mm Hg?

A)10
B)25
C)0
D)- 5
Question
Determine the correct order of the structure of the filtration membrane from deep to superficial.

A)basal lamina,podocytes,fenestrated glomerular capillary endothelial cells
B)fenestrated glomerular capillary endothelial cells,podocytes,basal lamina
C)podocytes,basal lamina,fenestrated glomerular capillary endothelial cells
D)fenestrated glomerular capillary endothelial cells,basal lamina,podocytes
Question
Jasmine has high blood pressure and an increased glomerular filtration rate (GFR).How does the tubuloglomerular feedback mechanism restore normal pressure in her glomerulus?

A)The juxtaglomerular (JG)cells increase production of renin.
B)The juxtaglomerular (JG)cells decrease production of renin.
C)The efferent arteriole constricts.
D)The afferent arteriole vasodilates.
Question
How does the vessel diameter of the afferent arteriole change in order to decrease glomerular hydrostatic pressure (GHP)and restore the glomerular filtration rate (GFR)to normal?

A)The afferent arteriole will vasodilate.
B)The afferent arteriole has no effect on GHP and GFR.
C)The afferent arteriole will vasoconstrict,then vasodilate.
D)The afferent arteriole will vasoconstrict.
Question
What effect does high blood pressure have on the glomerular filtration rate (GFR)in the absence of regulatory mechanisms?

A)GFR will decrease.
B)GFR will not change.
C)GFR will decrease,then increase.
D)GFR will increase.
Question
Filtrate traveling through the renal tubule travels from the thick ascending limb to the:

A)thin ascending limb of the nephron loop (loop of Henle).
B)thick descending limb of the nephron loop (loop of Henle).
C)distal tubule.
D)proximal tubule.
Question
Which statement best describes the function of tubular reabsorption?

A)Tubular reabsorption removes toxins from the blood that was not filtered.
B)Tubular reabsorption moves items from the peritubular capillary blood into the filtrate.
C)Tubular reabsorption moves blood plasma through the filtration membrane of the glomerular capillaries.
D)Tubular reabsorption reclaims items from filtrate and returns them to the blood.
Question
The main force that promotes filtration in a nephron is:

A)glomerular colloid osmotic pressure (GCOP).
B)capsular hydrostatic pressure (CHP).
C)glomerular hydrostatic pressure (GHP).
D)colloid osmotic pressure (COP).
Question
The cells of the macula densa and the juxtaglomerular (JG)cells form the:

A)nephron loop (loop of Henle).
B)filtration membrane.
C)renal corpuscle.
D)juxtaglomerular apparatus (JGA).
Question
Simple squamous epithelium is located in the:

A)descending limb of the nephron loop (loop of Henle).
B)proximal tubule.
C)ascending limb of the nephron loop (loop of Henle).
D)distal tubule.
Question
Which of these is a hormone that lowers blood volume and blood pressure?

A)angiotensin-II (A-II)
B)renin
C)aldosterone
D)atrial natriuretic peptide (ANP)
Question
Reabsorption of filtered glucose from the filtrate into the cells of the proximal tubule is by:

A)secondary active transport.
B)diffusion.
C)facilitated diffusion.
D)antiport.
Question
Which statement is TRUE regarding antidiuretic hormone (ADH)?

A)ADH promotes water loss and increases urine output.
B)ADH increases the permeability of the late distal tubule and cortical collecting ducts to water.
C)ADH causes the kidneys to produce very dilute urine.
D)ADH is secreted in response to low potassium ions in the blood.
Question
Sympathetic stimulation of the kidney can do all of the following,EXCEPT:

A)constrict both the afferent and efferent arterioles.
B)lower blood volume and blood pressure.
C)increase renin secretion.
D)increase blood concentration of angiotensin-II (A-II).
Question
Where are creatinine,ammonium ions,small amounts of urea,and drugs such as penicillin typically secreted?

A)ascending limb of the nephron loop (loop of Henle)
B)distal tubule
C)proximal tubule
D)collecting duct
Question
Which of the following will trigger the renin-angiotensin-aldosterone system (RAAS)into action?

A)low blood pressure
B)parasympathetic nervous system stimulation
C)high levels of sodium ions in the filtrate
D)an increase in systemic blood pressure
Question
A drug that inhibits angiotensin-converting enzyme (ACE)may lead to:

A)increased blood volume.
B)decreased blood pressure.
C)increased secretion of aldosterone.
D)increased sodium reabsorption.
Question
Which of the following enhances obligatory water reabsorption?

A)presence of aldosterone in the distal tubule
B)ATP
C)presence of high levels of glucose in the filtrate
D)aquaporins
Question
What is coupled with glucose reabsorption using a symporter in the early part of the proximal tubule?

A)sodium ions
B)amino acids
C)bicarbonate ions
D)hydrogen ions
Question
Dilute urine is more likely to be produced when:

A)antidiuretic hormone (ADH)release is decreased.
B)sodium and chloride ions are reabsorbed from the descending limb of the nephron loop (loop of Henle).
C)the distal tubule is permeable to water.
D)the collecting system is permeable to water.
Question
What does the countercurrent mechanism accomplish in the nephron loop?

A)secretion of water and electrolytes into the filtrate
B)production of very dilute urine
C)constriction of the arterioles to increase blood pressure
D)creation of a steep concentration gradient for continued water reabsorption
Question
Which of the following is NOT true about tubular reabsorption?

A)Tubular reabsorption may involve hormonal control.
B)Tubular reabsorption occurs via paracellular or transcellular routes.
C)Tubular reabsorption moves items from the filtrate into the blood.
D)Tubular reabsorption is entirely a passive process.
Question
What chemical is necessary for the transformation of angiotensin-I (A-I)into active angiotensin-II (A-II)?

A)angiotensinogen
B)angiotensin-converting enzyme (ACE)
C)renin
D)atrial natriuretic peptide (ANP)
Question
The reabsorption of bicarbonate ions in the proximal tubule helps regulate:

A)blood volume.
B)blood pH.
C)blood pressure.
D)blood solute concentration of sodium ions.
Question
Which hormones promote facultative water reabsorption?

A)antidiuretic hormone (ADH)and atrial natriuretic peptide (ANP)
B)atrial natriuretic peptide (ANP)and parathyroid hormone
C)aldosterone and atrial natriuretic peptide (ANP)
D)aldosterone and antidiuretic hormone (ADH)
Question
How much urine,in liters,is typically produced in a 24-hour period?

A)1)8
B)0)5
C)4)3
D)0)9
Question
Which of the following is an effect of angiotensin-II (A-II)?

A)A-II decreases blood volume.
B)A-II promotes thirst.
C)A-II dilates efferent arterioles.
D)A-II decreases systemic blood pressure.
Question
In the ascending limb of the nephron loop (loop of Henle),the:

A)thin segment is not permeable to sodium ions,chloride ions,or water.
B)movement of water and solutes is passive.
C)thick segment is permeable to water but impermeable to sodium and chloride ions.
D)thick segment is impermeable to water but permeable to sodium and chloride ions.
Question
How does atrial natriuretic peptide (ANP)contribute to a decrease in blood volume and systemic blood pressure?

A)ANP dilates the afferent arteriole and constricts the efferent arteriole.
B)ANP constricts the afferent arteriole and dilates the efferent arteriole.
C)ANP dilates both the afferent and efferent arterioles.
D)ANP constricts both the afferent and efferent arterioles.
Question
Each of the following is typical of urine EXCEPT:

A)translucency.
B)a pH of 3.0.
C)mild odor.
D)yellow color.
Question
The proximal tubule is lined with simple cuboidal epithelium and microvilli.
Question
Substances used to measure renal clearance should be:

A)filtered and reabsorbed,but not secreted.
B)secreted but neither filtered nor reabsorbed.
C)filtered,reabsorbed,and secreted.
D)completely filtered but neither reabsorbed nor secreted.
Question
What initiates the micturition reflex?

A)The external urethral sphincter relaxes.
B)The internal urethral sphincter relaxes.
C)Parasympathetic efferent fibers stimulate the contraction of the detrusor muscle.
D)Stretch receptors in the wall of the urinary bladder signal the sacral region of the spinal cord.
Question
What is renal clearance used to estimate?

A)countercurrent exchange
B)glomerular filtration rate (GFR)
C)net filtration pressure (NFP)
D)glomerular hydrostatic pressure (GHP)
Question
Urine dripping from a renal pyramid passes first into the major calyx then into the minor calyx.
Question
Glomerular hydrostatic pressure (GHP)is largely determined by systemic blood pressure.
Question
The yellow color of urine comes from the presence of:

A)sodium ions.
B)glucose.
C)ammonia.
D)urochrome.
Question
What process propels urine from the kidney to the urinary bladder in the ureters?

A)osmosis
B)secondary active transport
C)peristalsis
D)segmentation
Question
The majority of sodium ions are reclaimed through sodium ion leak channels in the proximal tubule.
Question
Creatinine,urea,uric acid,and ammonium ions are too large to pass through the filtration membrane.
Question
The function of the renin-angiotensin-aldosterone system (RAAS)is to decrease systemic blood pressure.
Question
Renal clearance is defined as:

A)the amount of filtrate that is reabsorbed during one day.
B)the percent of blood plasma that passes through the filtration membrane.
C)the amount of filtrate formed by both kidneys in one minute.
D)the rate at which the kidneys remove a substance from the blood.
Question
The trigone of the urinary bladder is created by:

A)the internal and external urethral sphincters.
B)the internal and external urethral orifices.
C)the openings to the two ureteral orifices and the internal urethral orifice.
D)the prostatic,membranous,and spongy urethra.
Question
Compared to the male urethra,the female urethra:

A)consists of the prostatic,membranous,and spongy regions.
B)is shorter.
C)has no external urethral sphincter.
D)transports both urine and semen.
Question
Hydrogen ion secretion leads to bicarbonate ions reabsorption in order to maintain proper blood pH balance.
Question
Filtrate and whole blood contain identical constituents.
Question
Since the thin descending limb of the nephron loop is permeable to water,and not very permeable to solutes,the concentration of the filtrate will increase as it reaches the bottom of the loop.
Question
Vasoconstriction of the afferent arteriole increases glomerular hydrostatic pressure (GHP)and the glomerular filtration rate (GFR).
Question
The glomerulus is fed and drained by arterioles.
Question
Voluntary neural control is necessary for:

A)contraction of the internal urethral sphincter.
B)relaxation of the internal urethral sphincter.
C)contraction of the detrusor muscle.
D)relaxation of the external urethral sphincter.
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Deck 24: The Urinary System
1
Which portion of the renal tubule has a brush border created by the presence of many microvilli?

A)distal tubule
B)descending limb of the nephron loop (loop of Henle)
C)proximal tubule
D)ascending limb of the nephron loop (loop of Henle)
C
2
What increases the permeability of the glomerulus by making the capillaries "leaky"?

A)microvilli
B)desmosomes
C)fenestrations
D)tight junctions
C
3
The portion of the renal tubule through which filtrate initially flows is known as the:

A)collecting duct.
B)nephron loop (loop of Henle).
C)distal tubule.
D)proximal tubule.
D
4
Identify the structure marked as "3."

A)distal tubule
B)renal corpuscle
C)proximal tubule
D)collecting duct
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5
What are the two main divisions of the nephron?

A)renal cortex and renal medulla
B)renal pyramids and renal columns
C)renal corpuscle and renal tubule
D)glomerulus and peritubular capillaries
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6
What external covering protects the kidney from physical shock?

A)renal pelvis
B)renal capsule
C)renal fascia
D)adipose capsule
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7
The functional units of the kidneys are:

A)renal sinuses.
B)nephrons.
C)renal pyramids.
D)glomeruli.
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8
Which of the following is NOT a major function of the kidneys?

A)regulation of blood volume and blood pressure
B)hematopoiesis
C)regulation of acid-base balance
D)removal of metabolic wastes
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9
Urine drains from a major calyx into:

A)the renal pelvis.
B)the renal tubule.
C)a papilla.
D)a minor calyx.
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10
A glomerulus is:

A)the source of erythropoietin.
B)attached to the collecting duct.
C)a set of capillaries within the renal corpuscle.
D)a hairpin loop segment of the renal tubule.
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11
Where does blood in the arcuate artery travel next on its journey toward the glomerulus?

A)interlobar artery
B)segmental artery
C)renal artery
D)interlobular (cortical radiate)artery
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12
Place these vessels in the correct order as blood flows into and through the kidney. 1.afferent arteriole
2)arcuate artery
3)efferent arteriole
4)glomerulus
5)interlobar artery
6)interlobular (cortical radiate)artery
7)renal artery
8)segmental artery

A)7,8,6,2,5,1,5,3
B)7,5,8,6,2,4,3,1
C)7,8,5,2,6,1,4,3
D)7,8,2,5,6,3,4,1
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13
Erythropoietin is produced by the kidneys to:

A)regulate red blood cell production by the bone marrow.
B)regulate blood solute concentration.
C)conserve or eliminate hydrogen and bicarbonate ions.
D)regulate removal of metabolic wastes.
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14
Which of the following is the capillary bed fed by the afferent arteriole and drained by the efferent arteriole?

A)peritubular capillaries
B)macula densa cells
C)vasa recta
D)glomerulus
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15
In which kidney region are the renal pyramids located?

A)renal sinus
B)renal cortex
C)renal medulla
D)renal pelvis
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16
Urine is transported from kidney to the urinary bladder by the:

A)aorta.
B)urethra.
C)ureter.
D)inferior vena cava.
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17
The right kidney sits to the left kidney due to the position of the liver.

A)posterior
B)inferior
C)superior
D)medial
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18
The indentation on the medial surface of the kidney is the:

A)pyramid.
B)calyx.
C)hilum.
D)pelvis.
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19
Which vessel is present in the arterial pathway but missing from the venous pathway?

A)interlobar
B)arcuate
C)interlobular (cortical radiate)
D)segmental
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20
What are the three main regions of the kidney?

A)renal pelvis,renal sinus,renal fascia
B)renal sinus,renal medulla,renal cortex
C)renal pelvis,renal medulla,renal cortex
D)renal sinus,renal pelvis,renal cortex
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21
Glomerular colloid osmotic pressure (GCOP)is created by:

A)proteins such as albumin in the blood.
B)fluids in the blood plasma.
C)systemic blood pressure.
D)filtrate in the capsular space.
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22
The myogenic mechanism acts to restore the glomerular filtration rate (GFR)by changing:

A)blood pH.
B)tubular secretion of metabolic wastes.
C)vessel diameter.
D)blood pressure.
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23
What is the normal value for the glomerular filtration rate (GFR)in mL/min?

A)275
B)125
C)75
D)500
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24
What should NOT be found in filtrate?

A)plasma proteins
B)acids and bases
C)metabolic wastes
D)water and electrolytes
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25
Items reclaimed during tubular reabsorption are returned to the:

A)minor calyx.
B)renal pelvis.
C)collecting system.
D)blood.
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26
The glomerular filtration rate is defined as:

A)the amount of filtrate formed by both kidneys in one minute.
B)the amount of filtrate that is reabsorbed during a 24-hour period.
C)the rate at which the kidneys remove a substance from the blood.
D)the percent of blood plasma that passes through the filtration membrane.
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27
What do the macula densa cells regulate in their role as part of the tubuloglomerular feedback loop?

A)changes in renal clearance
B)changes in glomerular hydrostatic pressure (GHP)
C)changes in blood pH
D)changes in the glomerular colloid osmotic pressure (GCOP)
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28
Podocytes in fenestrated glomerular capillaries prevent the filtration of large molecules such as:

A)albumin.
B)nitrogenous wastes.
C)amino acids.
D)glucose.
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29
Which of the following is NOT a true statement about the cortical nephrons?

A)Cortical nephrons are wrapped by the vasa recta.
B)Cortical nephrons have a short nephron loop (loop of Henle).
C)The renal corpuscle of a cortical nephron sits in the outer renal cortex.
D)Cortical nephrons are the most numerous type of nephron in the kidneys.
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30
The process of filtration occurs in the:

A)collecting duct.
B)distal tubule.
C)proximal tubule.
D)renal corpuscle.
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31
What is net filtration pressure (NFP)in the glomerular capillaries,in mm Hg?

A)10
B)25
C)0
D)- 5
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32
Determine the correct order of the structure of the filtration membrane from deep to superficial.

A)basal lamina,podocytes,fenestrated glomerular capillary endothelial cells
B)fenestrated glomerular capillary endothelial cells,podocytes,basal lamina
C)podocytes,basal lamina,fenestrated glomerular capillary endothelial cells
D)fenestrated glomerular capillary endothelial cells,basal lamina,podocytes
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33
Jasmine has high blood pressure and an increased glomerular filtration rate (GFR).How does the tubuloglomerular feedback mechanism restore normal pressure in her glomerulus?

A)The juxtaglomerular (JG)cells increase production of renin.
B)The juxtaglomerular (JG)cells decrease production of renin.
C)The efferent arteriole constricts.
D)The afferent arteriole vasodilates.
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34
How does the vessel diameter of the afferent arteriole change in order to decrease glomerular hydrostatic pressure (GHP)and restore the glomerular filtration rate (GFR)to normal?

A)The afferent arteriole will vasodilate.
B)The afferent arteriole has no effect on GHP and GFR.
C)The afferent arteriole will vasoconstrict,then vasodilate.
D)The afferent arteriole will vasoconstrict.
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35
What effect does high blood pressure have on the glomerular filtration rate (GFR)in the absence of regulatory mechanisms?

A)GFR will decrease.
B)GFR will not change.
C)GFR will decrease,then increase.
D)GFR will increase.
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36
Filtrate traveling through the renal tubule travels from the thick ascending limb to the:

A)thin ascending limb of the nephron loop (loop of Henle).
B)thick descending limb of the nephron loop (loop of Henle).
C)distal tubule.
D)proximal tubule.
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37
Which statement best describes the function of tubular reabsorption?

A)Tubular reabsorption removes toxins from the blood that was not filtered.
B)Tubular reabsorption moves items from the peritubular capillary blood into the filtrate.
C)Tubular reabsorption moves blood plasma through the filtration membrane of the glomerular capillaries.
D)Tubular reabsorption reclaims items from filtrate and returns them to the blood.
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38
The main force that promotes filtration in a nephron is:

A)glomerular colloid osmotic pressure (GCOP).
B)capsular hydrostatic pressure (CHP).
C)glomerular hydrostatic pressure (GHP).
D)colloid osmotic pressure (COP).
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39
The cells of the macula densa and the juxtaglomerular (JG)cells form the:

A)nephron loop (loop of Henle).
B)filtration membrane.
C)renal corpuscle.
D)juxtaglomerular apparatus (JGA).
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40
Simple squamous epithelium is located in the:

A)descending limb of the nephron loop (loop of Henle).
B)proximal tubule.
C)ascending limb of the nephron loop (loop of Henle).
D)distal tubule.
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41
Which of these is a hormone that lowers blood volume and blood pressure?

A)angiotensin-II (A-II)
B)renin
C)aldosterone
D)atrial natriuretic peptide (ANP)
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42
Reabsorption of filtered glucose from the filtrate into the cells of the proximal tubule is by:

A)secondary active transport.
B)diffusion.
C)facilitated diffusion.
D)antiport.
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43
Which statement is TRUE regarding antidiuretic hormone (ADH)?

A)ADH promotes water loss and increases urine output.
B)ADH increases the permeability of the late distal tubule and cortical collecting ducts to water.
C)ADH causes the kidneys to produce very dilute urine.
D)ADH is secreted in response to low potassium ions in the blood.
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44
Sympathetic stimulation of the kidney can do all of the following,EXCEPT:

A)constrict both the afferent and efferent arterioles.
B)lower blood volume and blood pressure.
C)increase renin secretion.
D)increase blood concentration of angiotensin-II (A-II).
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45
Where are creatinine,ammonium ions,small amounts of urea,and drugs such as penicillin typically secreted?

A)ascending limb of the nephron loop (loop of Henle)
B)distal tubule
C)proximal tubule
D)collecting duct
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46
Which of the following will trigger the renin-angiotensin-aldosterone system (RAAS)into action?

A)low blood pressure
B)parasympathetic nervous system stimulation
C)high levels of sodium ions in the filtrate
D)an increase in systemic blood pressure
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47
A drug that inhibits angiotensin-converting enzyme (ACE)may lead to:

A)increased blood volume.
B)decreased blood pressure.
C)increased secretion of aldosterone.
D)increased sodium reabsorption.
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48
Which of the following enhances obligatory water reabsorption?

A)presence of aldosterone in the distal tubule
B)ATP
C)presence of high levels of glucose in the filtrate
D)aquaporins
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49
What is coupled with glucose reabsorption using a symporter in the early part of the proximal tubule?

A)sodium ions
B)amino acids
C)bicarbonate ions
D)hydrogen ions
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50
Dilute urine is more likely to be produced when:

A)antidiuretic hormone (ADH)release is decreased.
B)sodium and chloride ions are reabsorbed from the descending limb of the nephron loop (loop of Henle).
C)the distal tubule is permeable to water.
D)the collecting system is permeable to water.
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51
What does the countercurrent mechanism accomplish in the nephron loop?

A)secretion of water and electrolytes into the filtrate
B)production of very dilute urine
C)constriction of the arterioles to increase blood pressure
D)creation of a steep concentration gradient for continued water reabsorption
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52
Which of the following is NOT true about tubular reabsorption?

A)Tubular reabsorption may involve hormonal control.
B)Tubular reabsorption occurs via paracellular or transcellular routes.
C)Tubular reabsorption moves items from the filtrate into the blood.
D)Tubular reabsorption is entirely a passive process.
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53
What chemical is necessary for the transformation of angiotensin-I (A-I)into active angiotensin-II (A-II)?

A)angiotensinogen
B)angiotensin-converting enzyme (ACE)
C)renin
D)atrial natriuretic peptide (ANP)
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54
The reabsorption of bicarbonate ions in the proximal tubule helps regulate:

A)blood volume.
B)blood pH.
C)blood pressure.
D)blood solute concentration of sodium ions.
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55
Which hormones promote facultative water reabsorption?

A)antidiuretic hormone (ADH)and atrial natriuretic peptide (ANP)
B)atrial natriuretic peptide (ANP)and parathyroid hormone
C)aldosterone and atrial natriuretic peptide (ANP)
D)aldosterone and antidiuretic hormone (ADH)
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56
How much urine,in liters,is typically produced in a 24-hour period?

A)1)8
B)0)5
C)4)3
D)0)9
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57
Which of the following is an effect of angiotensin-II (A-II)?

A)A-II decreases blood volume.
B)A-II promotes thirst.
C)A-II dilates efferent arterioles.
D)A-II decreases systemic blood pressure.
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58
In the ascending limb of the nephron loop (loop of Henle),the:

A)thin segment is not permeable to sodium ions,chloride ions,or water.
B)movement of water and solutes is passive.
C)thick segment is permeable to water but impermeable to sodium and chloride ions.
D)thick segment is impermeable to water but permeable to sodium and chloride ions.
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59
How does atrial natriuretic peptide (ANP)contribute to a decrease in blood volume and systemic blood pressure?

A)ANP dilates the afferent arteriole and constricts the efferent arteriole.
B)ANP constricts the afferent arteriole and dilates the efferent arteriole.
C)ANP dilates both the afferent and efferent arterioles.
D)ANP constricts both the afferent and efferent arterioles.
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60
Each of the following is typical of urine EXCEPT:

A)translucency.
B)a pH of 3.0.
C)mild odor.
D)yellow color.
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61
The proximal tubule is lined with simple cuboidal epithelium and microvilli.
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62
Substances used to measure renal clearance should be:

A)filtered and reabsorbed,but not secreted.
B)secreted but neither filtered nor reabsorbed.
C)filtered,reabsorbed,and secreted.
D)completely filtered but neither reabsorbed nor secreted.
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63
What initiates the micturition reflex?

A)The external urethral sphincter relaxes.
B)The internal urethral sphincter relaxes.
C)Parasympathetic efferent fibers stimulate the contraction of the detrusor muscle.
D)Stretch receptors in the wall of the urinary bladder signal the sacral region of the spinal cord.
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64
What is renal clearance used to estimate?

A)countercurrent exchange
B)glomerular filtration rate (GFR)
C)net filtration pressure (NFP)
D)glomerular hydrostatic pressure (GHP)
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65
Urine dripping from a renal pyramid passes first into the major calyx then into the minor calyx.
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66
Glomerular hydrostatic pressure (GHP)is largely determined by systemic blood pressure.
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67
The yellow color of urine comes from the presence of:

A)sodium ions.
B)glucose.
C)ammonia.
D)urochrome.
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68
What process propels urine from the kidney to the urinary bladder in the ureters?

A)osmosis
B)secondary active transport
C)peristalsis
D)segmentation
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69
The majority of sodium ions are reclaimed through sodium ion leak channels in the proximal tubule.
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70
Creatinine,urea,uric acid,and ammonium ions are too large to pass through the filtration membrane.
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71
The function of the renin-angiotensin-aldosterone system (RAAS)is to decrease systemic blood pressure.
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72
Renal clearance is defined as:

A)the amount of filtrate that is reabsorbed during one day.
B)the percent of blood plasma that passes through the filtration membrane.
C)the amount of filtrate formed by both kidneys in one minute.
D)the rate at which the kidneys remove a substance from the blood.
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73
The trigone of the urinary bladder is created by:

A)the internal and external urethral sphincters.
B)the internal and external urethral orifices.
C)the openings to the two ureteral orifices and the internal urethral orifice.
D)the prostatic,membranous,and spongy urethra.
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74
Compared to the male urethra,the female urethra:

A)consists of the prostatic,membranous,and spongy regions.
B)is shorter.
C)has no external urethral sphincter.
D)transports both urine and semen.
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75
Hydrogen ion secretion leads to bicarbonate ions reabsorption in order to maintain proper blood pH balance.
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76
Filtrate and whole blood contain identical constituents.
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77
Since the thin descending limb of the nephron loop is permeable to water,and not very permeable to solutes,the concentration of the filtrate will increase as it reaches the bottom of the loop.
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78
Vasoconstriction of the afferent arteriole increases glomerular hydrostatic pressure (GHP)and the glomerular filtration rate (GFR).
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79
The glomerulus is fed and drained by arterioles.
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80
Voluntary neural control is necessary for:

A)contraction of the internal urethral sphincter.
B)relaxation of the internal urethral sphincter.
C)contraction of the detrusor muscle.
D)relaxation of the external urethral sphincter.
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