Deck 20: Systemic and Local Drug Delivery Systems: Systemic Antibiotics, Local Drug Devices, and Enzyme Suppression Therapy

Question 1

Which of the following decides the choice of delivery system for antimicrobials/antibiotics?

A)Target site
B)Degree of absorption
C)Severity of side effects
D)Amount of drug administered

Answer 1

Target site

Question 2

Which of the following antibiotics is especially indicated for refractory periodontitis?

A)Clindamycin
B)Erythromycin
C)Metronidazole
D)Amoxicillin
E)Tetracycline

Answer 2

Clindamycin

Question 3

Which of the following antibiotics is most effective against strict anaerobes such as Porphyromonas gingivalis?

A)Metronidazole
B)Tetracycline
C)Doxycycline
D)Clindamycin

Answer 3

Metronidazole

Question 4

All of the following statements are true about doxycycline 20 mg except one. Which one is the exception?

A)It is an antibiotic.
B)It has no antibacterial action.
C)It inhibits collagenase production and release from host cells.
D)It is effectively used for nine months.
E)It is used in periodontics and dermatology.

Question 5

Which of the following drugs is highly concentrated in the gingival crevicular fluid (GCF)?

A)Tetracycline
B)Amoxicillin
C)Clindamycin
D)Erythromycin
E)Penicillin VK

Question 6

Which of the following drugs is found in Arestin?

A)Doxycycline hyclate
B)Minocycline HCl
C)Tetracycline HCl
D)Azithromycin HCl
E)Clindamycin HCl

Question 7

Which of the following ingredients is contained in Atridox?

A)Chlorhexidine
B)Doxycycline
C)Minocycline
D)Amoxicillin

Question 8

Which of the following antibiotics is contraindicated during pregnancy and in children up to age 8?

A)Erythromycin sterate
B)Clindamycin HCl
C)Cephalosporin
D)Amoxicillin
E)Tetracycline HCl

Question 9

Which of the following antibiotics is indicated in generalized chronic periodontitis?

A)Quinolone
B)Azithromycin
C)Amoxicillin
D)None

Question 10

The development of pseudomembranous colitis is associated with the growth of

A)Prevotella intermedia.
B)Porphyromonas gingivalis.
C)Clostridium difficle.
D)Treponema denticola.

Question 11

To which of the following delivery systems do Arestin and Atridox belong?

A)Topical
B)Local
C)Systemic
D)Rinse

Question 12

Which of the following antibiotics should not be taken with alcohol?

A)Penicillin
B)Erythromycin
C)Metronidazole
D)Azithromycin
E)Clindamycin

Question 13

For which of the following conditions are systemic antibiotics indicated?

A)Gingivitis
B)Generalized chronic periodontitis
C)Localized chronic periodontitis
D)Localized aggressive periodontitis

Question 14

In which of the following situations is doxycycline 20 mg indicated?

A)Chronic gingivitis
B)Necrotizing ulcerative periodontitis
C)Localized aggressive periodontitis
D)Generalized aggressive periodontitis
E)Generalized chronic periodontitis

Question 15

Which of the following antibiotics concentrates in phagocytes such as PMNs within the inflamed connective tissue?

A)Minocycline
B)Doxycycline
C)Amoxicillin
D)Azithromycin
E)Metronidazole

Question 16

Which of the following combination antibiotics is typically used in patients with localized aggressive periodontitis?

A)Amoxicillin + tetracycline
B)Metronidazole + amoxicillin
C)Tetracycline + doxycycline
D)Erythromycin + azithromycin
E)Clindamycin + erythromycin

Question 17

Which of the following antibiotics is classified as a second-generation macrolide?

A)Penicillin
B)Erythromycin
C)Metronidazole
D)Azithromycin
E)Clindamycin

Question 18

Which of the following antibiotics forms a complex with calcium during enamel formation?

A)Erythromycin
B)Amoxicillin
C)Ampicillin
D)Metronidazole
E)Doxycycline

Question 19

In which of the following structures is Atridox placed?

A)Periodontal pocket
B)Maxillary sinus
C)Alveolar bone
D)Connective tissue

Question 20

Which of the following ingredients is contained in PerioChip?

A)Chlorhexidine
B)Doxycycline
C)Minocycline
D)Amoxicillin

Question 21

Doxycycline has both antibacterial and ________ properties.

Question 22

Discuss the indications for systemic antibiotic usage in periodontics.

Question 23

Doxycycline 20 mg is dispensed as a ________.

Question 24

Doxycycline 20 mg inhibits enzymes produced and secreted by ________ in the host body.

Question 25

Arestin is a powder form of ________.

Question 26

Why is periodontal debridement (scaling and root planing)necessary before any form of antimicrobial or antibiotic is administered?

Question 27

Atridox is a gel form of ________ hyclate.