Deck 22: Fluid, Electrolyte, and Acid-Base Balance
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Deck 22: Fluid, Electrolyte, and Acid-Base Balance
1
The most abundant cation in extracellular fluid is
A)calcium
B)sodium
C)potassium
D)magnesium
E)hydrogen
A)calcium
B)sodium
C)potassium
D)magnesium
E)hydrogen
B
2
Water is lost from the body through the
A)kidneys
B)gastrointestinal tract
C)lungs
D)skin
E)all of the choices are correct
A)kidneys
B)gastrointestinal tract
C)lungs
D)skin
E)all of the choices are correct
E
3
The type of body fluid found inside cells is called
A)plasma
B)extracellular fluid
C)interstitial fluid
D)intracellular fluid
E)water
A)plasma
B)extracellular fluid
C)interstitial fluid
D)intracellular fluid
E)water
D
4
In lean adults, body fluid makes up about ____% of total body mass.
A)30-40
B)45-50
C)55-60
D)65-70
E)85-90
A)30-40
B)45-50
C)55-60
D)65-70
E)85-90
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5
In response to increased blood volume, ANP is secreted by cells in the
A)kidneys
B)adrenal glands
C)pituitary gland
D)hypothalamus
E)heart
A)kidneys
B)adrenal glands
C)pituitary gland
D)hypothalamus
E)heart
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6
All of the following hormones are involved in regulation of fluid balance in the body EXCEPT
A)ADH
B)ANP
C)CCK
D)angiotensin II
E)aldosterone
A)ADH
B)ANP
C)CCK
D)angiotensin II
E)aldosterone
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7
All of the following are signs and symptoms of hyponatremia EXCEPT
A)intense thirst
B)muscular weakness
C)dizziness
D)hypotension
E)tachycardia
A)intense thirst
B)muscular weakness
C)dizziness
D)hypotension
E)tachycardia
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8
Peritoneal fluid, pleural fluid, pericardial fluid, lymph, aqueous humor, endolymph, and perilymph are all considered to be
A)intracellular fluids
B)extracellular fluids
C)interstitial fluids
D)both extracellular fluid and interstitial fluid
E)none of the choices is correct
A)intracellular fluids
B)extracellular fluids
C)interstitial fluids
D)both extracellular fluid and interstitial fluid
E)none of the choices is correct
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9
Under normal conditions, daily water loss from the body is approximately
A)200 ml/day
B)2500 ml/day
C)400 ml/day
D)1500 ml/day
E)4300 ml/day
A)200 ml/day
B)2500 ml/day
C)400 ml/day
D)1500 ml/day
E)4300 ml/day
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10
The thirst center is located in the
A)medulla oblongata
B)hypothalamus
C)posterior pituitary gland
D)kidney
E)GI tract
A)medulla oblongata
B)hypothalamus
C)posterior pituitary gland
D)kidney
E)GI tract
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11
The dehydration sensors in the body stimulate the thirst center in response to
A)decreased flow of saliva.
B)increased osmotic pressure of blood plasma.
C)decreased blood volume.
D)increased osmotic pressure of blood plasma and decreased blood volume.
E)decreased flow of saliva, increased osmotic pressure of blood plasma, and decreased blood volume.
A)decreased flow of saliva.
B)increased osmotic pressure of blood plasma.
C)decreased blood volume.
D)increased osmotic pressure of blood plasma and decreased blood volume.
E)decreased flow of saliva, increased osmotic pressure of blood plasma, and decreased blood volume.
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12
Which of the following hormones stimulates increased urinary excretion of Na+?
A)norepinephrine
B)aldosterone
C)antidiuretic hormone
D)atrial natriuretic peptide
E)angiotensin II
A)norepinephrine
B)aldosterone
C)antidiuretic hormone
D)atrial natriuretic peptide
E)angiotensin II
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13
Release of ADH from the posterior pituitary gland is stimulated by
A)low osmotic pressure of interstitial fluid.
B)alcohol consumption.
C)increased blood volume.
D)increased osmotic pressure of plasma.
E)all of the choices are correct.
A)low osmotic pressure of interstitial fluid.
B)alcohol consumption.
C)increased blood volume.
D)increased osmotic pressure of plasma.
E)all of the choices are correct.
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14
Synovial fluid is an extracellular fluid found in
A)the inner ear
B)the middle ear
C)joints
D)serous membranes
E)both the inner ear and the middle ear
A)the inner ear
B)the middle ear
C)joints
D)serous membranes
E)both the inner ear and the middle ear
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15
The osmotic pressure of a solution is determined by
A)the number of particles dissolved in that solution.
B)the size of particles dissolved in that solution.
C)the weight of particles dissolved in that solution.
D)all of the choices are correct.
E)none of the choices is correct.
A)the number of particles dissolved in that solution.
B)the size of particles dissolved in that solution.
C)the weight of particles dissolved in that solution.
D)all of the choices are correct.
E)none of the choices is correct.
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16
A lower than normal level of potassium in the blood is referred to as
A)hyperkalemia
B)hypokalemia
C)hyponatremia
D)hypernatremia
E)hypochloremia
A)hyperkalemia
B)hypokalemia
C)hyponatremia
D)hypernatremia
E)hypochloremia
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17
The major difference in the composition of the plasma versus the interstitial fluid is
A)osmolarity.
B)concentration of carbohydrates.
C)concentration of solutes.
D)concentration of protein anions.
E)concentration of sodium ions.
A)osmolarity.
B)concentration of carbohydrates.
C)concentration of solutes.
D)concentration of protein anions.
E)concentration of sodium ions.
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18
Blood plasma is a component of
A)intracellular fluid
B)extracellular fluid
C)interstitial fluid
D)both extracellular fluid and intracellular fluid
E)none of the choices is correct
A)intracellular fluid
B)extracellular fluid
C)interstitial fluid
D)both extracellular fluid and intracellular fluid
E)none of the choices is correct
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19
Most solutes in body fluids are
A)electrolytes
B)proteins
C)sugars
D)amino acids
E)lipids
A)electrolytes
B)proteins
C)sugars
D)amino acids
E)lipids
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20
Which of the following extracellular fluids is found in the inner ear?
A)aqueous humor
B)endolymph
C)peritoneal fluid
D)synovial fluid
E)cerebrospinal fluid
A)aqueous humor
B)endolymph
C)peritoneal fluid
D)synovial fluid
E)cerebrospinal fluid
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21
All of the following are functions of ions in body fluids EXCEPT
A)control movement of water between fluid compartments.
B)help maintain acid-base balance.
C)used as neurotransmitters in the central nervous system.
D)carry electrical current across membranes.
E)serve as cofactors for enzymes.
A)control movement of water between fluid compartments.
B)help maintain acid-base balance.
C)used as neurotransmitters in the central nervous system.
D)carry electrical current across membranes.
E)serve as cofactors for enzymes.
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22
The most abundant buffer system in blood plasma and intracellular fluid is the
A)ammonium buffer system.
B)bicarbonate buffer system.
C)phosphate buffer system.
D)hemoglobin buffer system.
E)protein buffer system.
A)ammonium buffer system.
B)bicarbonate buffer system.
C)phosphate buffer system.
D)hemoglobin buffer system.
E)protein buffer system.
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23
The slowest mechanism for removing excess acids from the body fluids is
A)the protein buffer system.
B)the phosphate buffer system.
C)removal of carbon dioxide by the respiratory system.
D)urinary excretion.
E)the carbonic acid - bicarbonate buffer system.
A)the protein buffer system.
B)the phosphate buffer system.
C)removal of carbon dioxide by the respiratory system.
D)urinary excretion.
E)the carbonic acid - bicarbonate buffer system.
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24
Which of the following compartments contains most of the body's fluid?
A)blood
B)spaces between the cells in tissues
C)inside cells
D)joint cavities
E)lymphatic system
A)blood
B)spaces between the cells in tissues
C)inside cells
D)joint cavities
E)lymphatic system
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25
The acid-base balance depends on the concentration of
A)calcium ions
B)hydrogen ions
C)potassium ions
D)sodium ions
E)magnesium ions
A)calcium ions
B)hydrogen ions
C)potassium ions
D)sodium ions
E)magnesium ions
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26
All of the following are characteristics of buffer systems EXCEPT
A)buffers act quickly to bind excess H+.
B)buffers are found in all body fluids.
C)buffers are composed of combinations of a weak acid and weak base.
D)buffers are not present in excreted fluids like urine.
E)buffers do not eliminate excess H+ from the body.
A)buffers act quickly to bind excess H+.
B)buffers are found in all body fluids.
C)buffers are composed of combinations of a weak acid and weak base.
D)buffers are not present in excreted fluids like urine.
E)buffers do not eliminate excess H+ from the body.
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27
An increase in the carbon dioxide concentration of a body fluid results in
A)lower pH.
B)more acidic conditions.
C)higher pH.
D)lower pH and more acidic conditions.
E)more acidic conditions and higher pH.
A)lower pH.
B)more acidic conditions.
C)higher pH.
D)lower pH and more acidic conditions.
E)more acidic conditions and higher pH.
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28
Which of the following does NOT contribute to the impaired ability of older adults to maintain fluid, electrolyte and pH balance?
A)increased exhalation of carbon dioxide
B)decreased blood flow to the kidneys
C)decreased muscle mass
D)decreased glomerular filtration rate
E)increased adipose tissue
A)increased exhalation of carbon dioxide
B)decreased blood flow to the kidneys
C)decreased muscle mass
D)decreased glomerular filtration rate
E)increased adipose tissue
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29
Which of the following anions diffuses easily between extracellular and intracellular fluid compartments?
A)proteins
B)chloride
C)sulfate
D)phosphate
E)none of these anions move freely between ECF and ICF
A)proteins
B)chloride
C)sulfate
D)phosphate
E)none of these anions move freely between ECF and ICF
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30
The kidney helps to regulate pH of body fluids by
A)reabsorbing filtered bicarbonate.
B)secreting hydrogen ions into the urine.
C)reabsorbing sodium ions.
D)both reabsorbing filtered bicarbonate and reabsorbing sodium ions.
E)both reabsorbing filtered bicarbonate and secreting hydrogen ions.
A)reabsorbing filtered bicarbonate.
B)secreting hydrogen ions into the urine.
C)reabsorbing sodium ions.
D)both reabsorbing filtered bicarbonate and reabsorbing sodium ions.
E)both reabsorbing filtered bicarbonate and secreting hydrogen ions.
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31
The signs and symptoms of hypercalcemia include
A)lethargy
B)bone pain
C)muscle cramps
D)numbness and tingling of fingers
E)lethargy and bone pain
A)lethargy
B)bone pain
C)muscle cramps
D)numbness and tingling of fingers
E)lethargy and bone pain
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32
Which of the following is NOT considered to be an extracellular fluid of the body?
A)synovial fluid
B)cerebrospinal fluid
C)blood plasma and lymph
D)interstitial fluid
E)sarcoplasm of muscle cells
A)synovial fluid
B)cerebrospinal fluid
C)blood plasma and lymph
D)interstitial fluid
E)sarcoplasm of muscle cells
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33
Increased depth and rate of respiration
A)removes carbon dioxide from the blood.
B)reduces the hydrogen ion concentration in blood.
C)increases the pH of blood.
D)causes all of these events.
E)causes none of these events.
A)removes carbon dioxide from the blood.
B)reduces the hydrogen ion concentration in blood.
C)increases the pH of blood.
D)causes all of these events.
E)causes none of these events.
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34
Chemical substances in body fluids that prevent rapid changes in pH are called
A)cofactors
B)enzymes
C)coenzymes
D)buffers
E)free radicals
A)cofactors
B)enzymes
C)coenzymes
D)buffers
E)free radicals
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35
The major physiological effect of acidosis is
A)excitation of the central nervous system.
B)depression of the central nervous system.
C)excitation of cardiovascular center.
D)overexcitabilty of peripheral nerves.
E)inhibition of autonomic effectors.
A)excitation of the central nervous system.
B)depression of the central nervous system.
C)excitation of cardiovascular center.
D)overexcitabilty of peripheral nerves.
E)inhibition of autonomic effectors.
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36
The two ways that the body gains water are
A)through the skin and drinking.
B)ingestion and metabolism.
C)urine output and sweating.
D)defecation and ingestion.
E)ingestion and osmosis.
A)through the skin and drinking.
B)ingestion and metabolism.
C)urine output and sweating.
D)defecation and ingestion.
E)ingestion and osmosis.
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37
Which of the following is the major extracellular anion?
A)phosphate
B)calcium
C)magnesium
D)chloride
E)potassium
A)phosphate
B)calcium
C)magnesium
D)chloride
E)potassium
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38
Assuming that one liter of body fluid weighs one kilogram, how many liters of water would you find in a normal 70 kg adult male?
A)42 liters
B)45 liters
C)60 liters
D)28 liters
E)14 liters
A)42 liters
B)45 liters
C)60 liters
D)28 liters
E)14 liters
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39
Which of the following body fluid compartments is the largest?
A)extracellular fluid
B)intracellular fluid
C)interstitial fluid
D)plasma
E)lymph
A)extracellular fluid
B)intracellular fluid
C)interstitial fluid
D)plasma
E)lymph
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40
The pH of extracellular fluid, such as blood plasma, of a healthy person is
A)highly acidic
B)slightly acidic
C)neutral
D)slightly basic
E)highly basic
A)highly acidic
B)slightly acidic
C)neutral
D)slightly basic
E)highly basic
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41
Body fluids lost by excessive sweating during physical activity are most efficiently replaced by drinking pure water.
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42
Both electrolytes and water can be lost through the processes of perspiration, defecation, and urination.
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43
Using hypoventilation or hyperventilation to help balance pH is called respiratory compensation.
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44
Glucose is one of the major electrolytes in plasma.
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45
Due to a decrease in the number and efficiency of sweat glands, water loss from the skin declines with age.
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46
Phosphate is mainly an intracellular anion.
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47
Because acidosis results in increased excitation of the neurons of the central nervous system, it can cause convulsions and muscle spasms.
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48
A decrease in the sodium concentration of plasma causes the release of ADH from the posterior pituitary gland.
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49
Calcium is involved in blood clotting.
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50
Which of the following is a weak base that can be used to buffer the intracellular accumulation of acid that occurs during metabolism?
A)carbonic acid
B)monohydrogen phosphate
C)carbon dioxide
D)hydroxide ions
E)carbonic anhydrase
A)carbonic acid
B)monohydrogen phosphate
C)carbon dioxide
D)hydroxide ions
E)carbonic anhydrase
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51
Sodium is a strong acid that can be neutralized by bicarbonate.
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52
Dehydration decreases the production of saliva.
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53
The ionic composition of extracellular and intracellular fluids differs considerably.
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54
More acids than bases are produced by normal cellular metabolism.
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55
During activities that lead to excessive sweating, it is wise to begin drinking fluids even before the sensation of thirst appears.
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56
Changes in the breathing rate can be used to help maintain blood pH.
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57
Aldosterone is the main hormone that regulates calcium concentrations in the blood.
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58
Taking diuretics usually has no effect on fluid or electrolyte balance.
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59
Excessive fluid accumulation in the blood results in hypotension.
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60
Osmotic pressure of body fluids plays an important role in maintaining both water and electrolyte balance.
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61
Acidosis and alkalosis have opposite effects on the central nervous system; the former depresses it while the latter excites it.
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62
All of the following have been shown to lead to low bone density in later life EXCEPT
A)low calcium intake in diet.
B)high sodium intake in diet.
C)high protein intake in diet.
D)high intake of grains in diet.
E)high intake of fruits in diet.
A)low calcium intake in diet.
B)high sodium intake in diet.
C)high protein intake in diet.
D)high intake of grains in diet.
E)high intake of fruits in diet.
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63
Vitamin D is a fat-soluble vitamin that is converted to calcitriol, which promotes the intestinal absorption of
A)sodium
B)potassium
C)phosphate
D)bicarbonate
E)calcium
A)sodium
B)potassium
C)phosphate
D)bicarbonate
E)calcium
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64
Using the percentages and fractions given in the diagram, what would the volume of interstitial fluid be in an average male with a body weight of 100 kilograms? 
A)60 liters
B)40 liters
C)20 liters
D)16 liters
E)4 liters

A)60 liters
B)40 liters
C)20 liters
D)16 liters
E)4 liters
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65
Which of the following answer selections best describes the series of steps (labeled C, D and E in the diagram)that occur between decreased blood volume and stimulation of the thirst centers? 
A)C = ↓ blood pressure; D = ↑angiotensin II formation; E = ↑ renin release by kidneys
B)C = ↓ blood pressure; D = ↑ renin release by kidneys; E = ↑ angiotensin II formation
C)C = ↑ renin release by kidneys; D = ↑angiotensin II formation; E = ↓ blood pressure
D)C = ↑ blood pressure; D = ↑ renin release by kidneys; E = ↑ angiotensin II formation
E)C = ↑ blood pressure; D = ↑ angiotensin II formation; E = ↑ renin release by kidneys

A)C = ↓ blood pressure; D = ↑angiotensin II formation; E = ↑ renin release by kidneys
B)C = ↓ blood pressure; D = ↑ renin release by kidneys; E = ↑ angiotensin II formation
C)C = ↑ renin release by kidneys; D = ↑angiotensin II formation; E = ↓ blood pressure
D)C = ↑ blood pressure; D = ↑ renin release by kidneys; E = ↑ angiotensin II formation
E)C = ↑ blood pressure; D = ↑ angiotensin II formation; E = ↑ renin release by kidneys
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66
Dehydration causes a loss of only interstitial fluid.
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67
Which labeled section of the bar graphs represents the blood plasma? 
A)F
B)B
C)C
D)D
E)E

A)F
B)B
C)C
D)D
E)E
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68
Explain water intoxication.
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69
Which of the following sections of the bar graphs shown in the diagram would increase the most in an obese individual? 
A)A
B)B
C)C
D)D
E)E

A)A
B)B
C)C
D)D
E)E
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70
The thirst mechanism is an unreliable indicator of fluid needs, especially in children and older adults.
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71
What type of receptors (labeled B in the diagram)are used to sense increased blood osmotic pressure? 
A)baroreceptors
B)nociceptors
C)proprioceptors
D)mechanoreceptors
E)osmoreceptors

A)baroreceptors
B)nociceptors
C)proprioceptors
D)mechanoreceptors
E)osmoreceptors
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72
Explain how dehydration is detected and how this detection leads to activation of the thirst center.
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73
Which of the following solutes would have the unique body fluid distribution pattern that is labeled I in the graph? 
A)sodium
B)potassium
C)calcium
D)phosphate
E)protein anions

A)sodium
B)potassium
C)calcium
D)phosphate
E)protein anions
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74
Name the major ions found in body fluids and briefly describe their primary location.
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75
When the plasma concentration of calcium decreases below normal, calcitonin is released from the thyroid gland to stimulate bone resorption leading to the release of calcium.
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76
During dehydration, the receptors that sense a decreased flow of saliva (labeled A in the diagram)are found in 
A)the mouth
B)the salivary glands
C)the pharynx
D)both the mouth and the pharynx
E)all of the choices are correct

A)the mouth
B)the salivary glands
C)the pharynx
D)both the mouth and the pharynx
E)all of the choices are correct
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77
Which of the labeled sets of bars in the graph would best represent the concentration of potassium ions in the body fluids? 
A)A
B)B
C)C
D)D
E)E

A)A
B)B
C)C
D)D
E)E
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78
Which of the labeled sets of bars in the graph would best represent the concentration of sodium ions in the body fluids? 
A)A
B)B
C)E
D)G
E)I

A)A
B)B
C)E
D)G
E)I
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79
Dehydration only affects the volume of the extracellular fluid compartment.
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80
An increase in the CO2 concentration of the plasma leads to a drop in its pH.
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