Deck 54: Biological Response–Modifying Drugs

Question 1

A patient is receiving interferon therapy.What expected adverse effect should the nurse tell this patient about?

A)Anemia
B)Increased appetite
C)Constipation
D)Flulike effects

Answer 1

Flulike effects

Question 2

A female patient is being treated with biological response-modifying drugs.After the completion of her treatment,she should be cautioned to avoid pregnancy for what time period?

A)6 months
B)12 months
C)18 months
D)24 months

Answer 2

24 months

Question 3

When providing patient education related to biological response-modifying drugs,which is important information to give the patient?

A)Interleukins cannot be self-administered.
B)Any temperature higher than 39.5°C needs to be reported to the health care provider.
C)Pregnancy should be avoided for 6 months.
D)Adverse effects usually disappear within 72 to 96 hours after therapy is discontinued.

Answer 3

Adverse effects usually disappear within 72 to 96 hours after therapy is discontinued.

Question 4

Which medication is indicated in the treatment of rheumatoid arthritis?

A)thalidomide (Thalomid)
B)tretinoin (Vesanoid)
C)bacillus Calmette-Guérin (BCG) vaccine (Immuncyst)
D)etanercept (Enbrel)

Question 5

Capillary leak syndrome during interleukin therapy may result in which problem?

A)Renal failure
B)Asthma
C)Ecchymosis
D)Heart failure

Question 6

A patient is to take antineoplastic therapy with monoclonal antibodies such as rituximab (Rituxan).The nurse should carefully assess this patient for which condition?

A)Anorexia
B)Neuropathy
C)Respiratory problems
D)Heart failure

Question 7

A patient with end-stage renal failure has been admitted to hospital for severe anemia but is refusing blood transfusions.Which drugs will likely be used to stimulate the production of red blood cells (RBCs)?

A)filgrastim (Neupogen)
B)interferon
C)epoetin alfa (Eprex)
D)sargramostim (Leukine)

Question 8

Lymphokine-activated killer (LAK)cells,which multiply as a result of interleukin therapy,do what?

A)They directly inhibit deoxyribonucleic acid (DNA) and protein synthesis.
B)They destroy cancer cells and ignore normal cells.
C)They destroy cancer cells by destroying all types of cells.
D)They prevent virus replication and prevent viruses from penetrating healthy cells.

Question 9

Which is true in regard to therapy with interferon drugs?

A)Dosages should be administered in the morning.
B)The patient should be encouraged to drink up to 2 to 3 L of fluids per day while taking these medications.
C)To minimize allergic reactions, oral dosing is preferred.
D)Shake the drug vial well before drawing up a dose.

Question 10

Which is an effect of colony-stimulating factors (CSFs)?

A)Multiplication of T cells
B)Decreased neutrophil counts
C)Increased cytotoxic activity of natural killer (NK) cells
D)Stimulation of certain immune cells