Deck 16: The Endocrine System
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Deck 16: The Endocrine System
1
A simple endocrine reflex involves _ hormones).
A) one
B) five
C) few
D) more than 15
E) none of the above
A) one
B) five
C) few
D) more than 15
E) none of the above
A
2
The delta cells of the pancreatic islets produce
A) cortisol.
B) peptide P.
C) glucagon.
D) insulin.
E) somatostatin.
A) cortisol.
B) peptide P.
C) glucagon.
D) insulin.
E) somatostatin.
E
3
A hormone that can lower blood levels of calcium ion is
A) glucagon.
B) parathyroid hormone.
C) calcitonin.
D) oxytocin.
E) thyroxine.
A) glucagon.
B) parathyroid hormone.
C) calcitonin.
D) oxytocin.
E) thyroxine.
C
4
The zona reticularis of the suprarenal cortex produces
A) mineralocorticoids.
B) glucocorticoids.
C) epinephrine.
D) androgens.
E) norepinephrine.
A) mineralocorticoids.
B) glucocorticoids.
C) epinephrine.
D) androgens.
E) norepinephrine.
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5
The condition known as goiter can result from too
A) little TSH.
B) much ACTH.
C) little iodine in the diet.
D) little glucagon.
E) much insulin.
A) little TSH.
B) much ACTH.
C) little iodine in the diet.
D) little glucagon.
E) much insulin.
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6
The two lobes of the pituitary gland together produce how many hormones?
A) 7
B) 3
C) 16
D) 9
E) 5
A) 7
B) 3
C) 16
D) 9
E) 5
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7
The hormone that plays a pivotal role in setting the metabolic rate and thus impacting body temperature is
A) glucagon.
B) parathyroid hormone.
C) calcitonin.
D) thyroxine.
E) somatotropin.
A) glucagon.
B) parathyroid hormone.
C) calcitonin.
D) thyroxine.
E) somatotropin.
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8
If the median eminence of the hypothalamus is destroyed, the hypothalamus would no longer be able to control the secretion of which of the following hormones?
A) TSH
B) ACTH
C) PRL
D) ADH
E) A, B, and C
A) TSH
B) ACTH
C) PRL
D) ADH
E) A, B, and C
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9
Thyroid hormone contains the element
A) chlorine.
B) fluorine.
C) iodine.
D) zinc.
E) iron.
A) chlorine.
B) fluorine.
C) iodine.
D) zinc.
E) iron.
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10
Norepinephrine and epinephrine are considered to be when released into the bloodstream, but _ when released at synapses.
A) hormones; neurotransmitters
B) neuropeptides; neurohormones
C) neuropeptides; neurotransmitters
D) neurotransmitters; hormones
E) neurotransmitters; neuropeptides
A) hormones; neurotransmitters
B) neuropeptides; neurohormones
C) neuropeptides; neurotransmitters
D) neurotransmitters; hormones
E) neurotransmitters; neuropeptides
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11
Follicle cells in the ovary secrete when stimulated by FSH.
A) progesterone
B) testosterone
C) gonadotropins
D) inhibin
E) estrogen
A) progesterone
B) testosterone
C) gonadotropins
D) inhibin
E) estrogen
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12
The pituitary hormone that causes the kidney to reduce water loss is
A) TSH.
B) ADH.
C) FSH.
D) MSH.
E) STH.
A) TSH.
B) ADH.
C) FSH.
D) MSH.
E) STH.
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13
The link between a first messenger and a second messenger in a cell that responds to peptide hormones is usually
A) a G protein.
B) cAMP.
C) adenyl cyclase.
D) cGMP.
E) calcium ion levels.
A) a G protein.
B) cAMP.
C) adenyl cyclase.
D) cGMP.
E) calcium ion levels.
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14
Increased activity of phosphodiesterase in a target cell would decrease its level of
A) thyroid hormone.
B) testosterone.
C) progesterone.
D) cAMP.
E) estrogen.
A) thyroid hormone.
B) testosterone.
C) progesterone.
D) cAMP.
E) estrogen.
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15
Decreased blood flow to the kidneys would lead to which of the following?
A) increased blood levels of renin
B) increased blood levels of erythropoietin
C) elevated blood levels of angiotensin
D) all of the above
E) B and C only
A) increased blood levels of renin
B) increased blood levels of erythropoietin
C) elevated blood levels of angiotensin
D) all of the above
E) B and C only
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16
The zona fasciculata of the suprarenal cortex produces
A) mineralocorticoids.
B) androgens.
C) glucocorticoids.
D) norepinephrine.
E) epinephrine.
A) mineralocorticoids.
B) androgens.
C) glucocorticoids.
D) norepinephrine.
E) epinephrine.
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17
Damage to cells of the zona fasciculata of the suprarenal cortex would result in
A) the loss of axillary and pubic hair.
B) increased water retention.
C) decreased levels of sodium ion in the blood.
D) decreased ability to convert amino acids to glucose.
E) increased volume of urine formation.
A) the loss of axillary and pubic hair.
B) increased water retention.
C) decreased levels of sodium ion in the blood.
D) decreased ability to convert amino acids to glucose.
E) increased volume of urine formation.
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18
Reduction of fluid losses at the kidneys due to the retention of Na+ is the action of
A) antidiuretic hormone.
B) calcitonin.
C) oxytocin.
D) cortisone.
E) aldosterone.
A) antidiuretic hormone.
B) calcitonin.
C) oxytocin.
D) cortisone.
E) aldosterone.
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19
Before the discovery of these glands, thyroid surgery often led to a rapid drop in blood calcium levels, which triggered muscle contractions and cardiac arrhythmias. What glands are these and which hormone is lacking?
A) parathyroid glands; calcitonin
B) parathyroid glands; parathyroid hormone
C) parathyroid glands; levothyroxine
D) thyroid glands; levothyroxine
E) thyroid glands; calcitonin
A) parathyroid glands; calcitonin
B) parathyroid glands; parathyroid hormone
C) parathyroid glands; levothyroxine
D) thyroid glands; levothyroxine
E) thyroid glands; calcitonin
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20
Which of these statements about melatonin is false?
A) exposure to light inhibits production
B) made from serotonin
C) inhibits releases of GnRH
D) exposure to light stimulates production
E) produced by pinealocytes
A) exposure to light inhibits production
B) made from serotonin
C) inhibits releases of GnRH
D) exposure to light stimulates production
E) produced by pinealocytes
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21
The condition known as seasonal affective disorder SAD) may be caused by
A) increased levels of melanocyte- stimulating hormone.
B) increased levels of melanin.
C) increased levels of melatonin.
D) increased levels of gonadotrophins.
E) both B and D
A) increased levels of melanocyte- stimulating hormone.
B) increased levels of melanin.
C) increased levels of melatonin.
D) increased levels of gonadotrophins.
E) both B and D
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22
Which of the following is a known effect of thyroid hormone on peripheral tissues?
A) increased sensitivity to adrenergic stimulation
B) increased heart rate
C) increased body temperature
D) increased oxygen consumption
E) all of the above
A) increased sensitivity to adrenergic stimulation
B) increased heart rate
C) increased body temperature
D) increased oxygen consumption
E) all of the above
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23
The most complex endocrine responses involve the
A) suprarenal glands.
B) pancreas.
C) thyroid gland.
D) thymus gland.
E) hypothalamus.
A) suprarenal glands.
B) pancreas.
C) thyroid gland.
D) thymus gland.
E) hypothalamus.
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24
Calcium ions serve as messengers, often in combination with the intracellular protein
A) calmodulin.
B) calcium- binding globulin.
C) calcitropin.
D) calcitriol.
E) calcitonin.
A) calmodulin.
B) calcium- binding globulin.
C) calcitropin.
D) calcitriol.
E) calcitonin.
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25
Each of the following hormones is an amino acid derivative, except
A) thyroid hormone.
B) norepinephrine.
C) melatonin.
D) epinephrine.
E) thyroid- stimulating hormone.
A) thyroid hormone.
B) norepinephrine.
C) melatonin.
D) epinephrine.
E) thyroid- stimulating hormone.
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26
When blood glucose levels fall,
A) glucagon is released.
B) insulin is released.
C) peripheral cells take up more glucose.
D) protein synthesis increases.
E) both B and D
A) glucagon is released.
B) insulin is released.
C) peripheral cells take up more glucose.
D) protein synthesis increases.
E) both B and D
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27
After a steroid hormone binds to its receptor to form an active complex,
A) cyclic nucleotides are formed.
B) protein kinases are activated.
C) adenyl cyclase is activated.
D) gene transcription is initiated.
E) G proteins are phosphylated.
A) cyclic nucleotides are formed.
B) protein kinases are activated.
C) adenyl cyclase is activated.
D) gene transcription is initiated.
E) G proteins are phosphylated.
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28
If the adenyl cyclase activity of liver cells were missing, which of these hormones could no longer stimulate release of glucose?
A) insulin
B) thyroxine
C) epinephrine
D) leptin
E) cortisol
A) insulin
B) thyroxine
C) epinephrine
D) leptin
E) cortisol
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29
If a diabetic patient received too much insulin, the low blood sugar could be corrected by injecting
A) thyroid hormone.
B) antidiuretic hormone.
C) aldosterone.
D) GHIH.
E) glucagon.
A) thyroid hormone.
B) antidiuretic hormone.
C) aldosterone.
D) GHIH.
E) glucagon.
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30
Proper growth requires which of these hormones?
A) insulin
B) thyroid hormone
C) growth hormone
D) calcitriol
E) all of the above
A) insulin
B) thyroid hormone
C) growth hormone
D) calcitriol
E) all of the above
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31
Melatonin is produced by the
A) skin.
B) pineal gland.
C) thymus.
D) kidneys.
E) heart.
A) skin.
B) pineal gland.
C) thymus.
D) kidneys.
E) heart.
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32
Alpha cells are to as beta cells are to .
A) glucagon; somatostatin
B) glucagon; insulin
C) insulin; glucagon
D) somatostatin; insulin
E) pancreatic polypeptide; insulin
A) glucagon; somatostatin
B) glucagon; insulin
C) insulin; glucagon
D) somatostatin; insulin
E) pancreatic polypeptide; insulin
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33
After brain surgery, a patient receiving postoperative care in an intensive care unit began to pass large volumes of very dilute urine. The ICU nurse administered a medicine that mimics one of the following hormones. Which one?
A) cortisol
B) ADH
C) aldosterone
D) epinephrine
E) renin
A) cortisol
B) ADH
C) aldosterone
D) epinephrine
E) renin
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34
Hormonal actions on cells include those that affect
A) gating of ion channels.
B) quantities of enzymes.
C) synthesis of enzymes.
D) activities of enzymes.
E) any of the above
A) gating of ion channels.
B) quantities of enzymes.
C) synthesis of enzymes.
D) activities of enzymes.
E) any of the above
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35
The pituitary hormone that triggers the release of thyroid hormone from the thyroid gland is
A) TSH.
B) ACTH.
C) GH.
D) LH.
E) FSH.
A) TSH.
B) ACTH.
C) GH.
D) LH.
E) FSH.
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36
Cushing disease results from an excess of
A) glucocorticoids.
B) ADH.
C) epinephrine.
D) parathyroid hormone.
E) growth hormone.
A) glucocorticoids.
B) ADH.
C) epinephrine.
D) parathyroid hormone.
E) growth hormone.
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37
Hormones known as "catecholamines" are
A) lipids.
B) steroids.
C) peptides.
D) derivatives of the amino acid tyrosine.
E) derivatives of reproductive glands.
A) lipids.
B) steroids.
C) peptides.
D) derivatives of the amino acid tyrosine.
E) derivatives of reproductive glands.
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38
The pituitary hormone that controls the release of glucocorticoids from the suprarenal cortex is
A) FSH.
B) ACTH.
C) LH.
D) TSH.
E) GH.
A) FSH.
B) ACTH.
C) LH.
D) TSH.
E) GH.
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39
All of the following are true of the nervous system, except that it doesn't
A) respond specifically to stimuli.
B) communicate by the release of neurotransmitters.
C) function independently of the endocrine system.
D) respond rapidly to stimuli.
E) respond with motor output.
A) respond specifically to stimuli.
B) communicate by the release of neurotransmitters.
C) function independently of the endocrine system.
D) respond rapidly to stimuli.
E) respond with motor output.
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40
TSH plays a key role in the of thyroid hormones.
A) inhibition
B) synthesis
C) release
D) both A and B
E) both B and C
A) inhibition
B) synthesis
C) release
D) both A and B
E) both B and C
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41
Which of the following substances activates protein kinases and thus acts as a second messenger?
A) epinephrine
B) cyclic AMP
C) TSH
D) ACTH
E) insulin
A) epinephrine
B) cyclic AMP
C) TSH
D) ACTH
E) insulin
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42
When blood glucose levels rise,
A) peripheral cells break down glycogen.
B) peripheral cells take up less glucose.
C) insulin is released.
D) glucagon is released.
E) protein synthesis decreases.
A) peripheral cells break down glycogen.
B) peripheral cells take up less glucose.
C) insulin is released.
D) glucagon is released.
E) protein synthesis decreases.
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43
The enzyme renin is responsible for the activation of
A) cortisol.
B) angiotensin.
C) atrial natriuretic peptide.
D) adrenaline.
E) erythropoietin.
A) cortisol.
B) angiotensin.
C) atrial natriuretic peptide.
D) adrenaline.
E) erythropoietin.
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44
Pinealocytes produce
A) melatonin.
B) LH.
C) FSH.
D) MSH.
E) melanin.
A) melatonin.
B) LH.
C) FSH.
D) MSH.
E) melanin.
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45

Use Figure 16- 1 to answer the following questions:
The functional organization of the nervous system parallels that of the _ system in many ways.
A) hepatic
B) muscular
C) body
D) endocrine
E) cardiovascular
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46
Thyroxine and calcitonin are secreted by the
A) gonads.
B) kidneys.
C) heart.
D) thyroid gland.
E) pituitary gland.
A) gonads.
B) kidneys.
C) heart.
D) thyroid gland.
E) pituitary gland.
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47
Regulatory factors that control secretion of adenohypophyseal hormones are released by neurons at the of the hypothalamus.
A) paraventricular nuclei
B) infundibulum
C) supraoptic nuclei
D) median eminence
E) geniculate bodies
A) paraventricular nuclei
B) infundibulum
C) supraoptic nuclei
D) median eminence
E) geniculate bodies
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48
Which of the following organs contain target cells for oxytocin?
A) ductus deferens
B) mammary glands
C) uterus
D) prostate
E) all of the above
A) ductus deferens
B) mammary glands
C) uterus
D) prostate
E) all of the above
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49
A rise in angiotensin II levels would result in all of the following, except
A) increased blood volume.
B) increased urine production.
C) elevated blood pressure.
D) increased water retention.
E) increased retention of sodium ions at the kidney.
A) increased blood volume.
B) increased urine production.
C) elevated blood pressure.
D) increased water retention.
E) increased retention of sodium ions at the kidney.
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50
Liver cells respond to growth hormone by releasing hormones called
A) prostaglandins.
B) glucocorticoids.
C) gonadotrophins.
D) hepatic hormones.
E) somatomedins.
A) prostaglandins.
B) glucocorticoids.
C) gonadotrophins.
D) hepatic hormones.
E) somatomedins.
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51
The hypothalamus acts as both a neural and an) _ organ.
A) hepatic
B) cardiovascular
C) endocrine
D) muscular
E) renal
A) hepatic
B) cardiovascular
C) endocrine
D) muscular
E) renal
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52
Angiotensin I is converted to angiotensin II by converting enzymes in the
A) heart.
B) lungs.
C) blood.
D) liver.
E) kidneys.
A) heart.
B) lungs.
C) blood.
D) liver.
E) kidneys.
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53
The beta cells of the pancreatic islets produce
A) peptide P.
B) somatostatin.
C) cortisol.
D) glucagon.
E) insulin.
A) peptide P.
B) somatostatin.
C) cortisol.
D) glucagon.
E) insulin.
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54
Endocrine cells
A) release their secretions directly into body fluids.
B) contain few vesicles.
C) are a type of nerve cell.
D) release their secretions onto an epithelial surface.
E) are modified connective- tissue cells.
A) release their secretions directly into body fluids.
B) contain few vesicles.
C) are a type of nerve cell.
D) release their secretions onto an epithelial surface.
E) are modified connective- tissue cells.
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55
The pancreatic hormone that causes blood sugar to enter its target cells is
A) insulin.
B) somatotropin.
C) erythropoietin.
D) glucagon.
E) cortisol.
A) insulin.
B) somatotropin.
C) erythropoietin.
D) glucagon.
E) cortisol.
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56
The hormone that does the opposite of calcitonin is
A) insulin.
B) thyroid hormone.
C) glucagon.
D) growth hormone.
E) parathyroid hormone.
A) insulin.
B) thyroid hormone.
C) glucagon.
D) growth hormone.
E) parathyroid hormone.
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57
The action of thyroid hormone on a target cell involves all these steps except one. Identify the incorrect step.
A) binding to a cytoplasmic receptor protein
B) specific transport into the target cell
C) binding to a hormone receptor in the plasma membrane
D) activation of a specific gene
E) activation of mitochondria
A) binding to a cytoplasmic receptor protein
B) specific transport into the target cell
C) binding to a hormone receptor in the plasma membrane
D) activation of a specific gene
E) activation of mitochondria
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58
A kinase is an enzyme that performs
A) active transport.
B) as a membrane channel.
C) phosphorylation.
D) both A and B
E) both A and C
A) active transport.
B) as a membrane channel.
C) phosphorylation.
D) both A and B
E) both A and C
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59
When adenyl cyclase is activated,
A) ATP is consumed.
B) cAMP is formed.
C) cAMP is broken down.
D) B, C, and D
E) only A and B
A) ATP is consumed.
B) cAMP is formed.
C) cAMP is broken down.
D) B, C, and D
E) only A and B
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60

Use Figure 16- 1 to answer the following questions:
Identify the hormone labeled "5."
A) thyrotropin
B) parathyroid hormone PTH)
C) thyroid- releasing hormone
D) thyroid- stimulating hormone
E) thyroxin
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61
Steroid hormones
A) bind to receptors in the nucleus of their target cells.
B) are transported in the blood dissolved in the plasma.
C) remain in circulation for relatively short periods of time.
D) are proteins.
E) cannot diffuse through cell membranes.
A) bind to receptors in the nucleus of their target cells.
B) are transported in the blood dissolved in the plasma.
C) remain in circulation for relatively short periods of time.
D) are proteins.
E) cannot diffuse through cell membranes.
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62
A structure known as the corpus luteum secretes
A) cortisone.
B) aldosterone.
C) progesterone.
D) testosterone.
E) androstenedione.
A) cortisone.
B) aldosterone.
C) progesterone.
D) testosterone.
E) androstenedione.
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63
Which of the following is not an action of TSH?
A) inhibits T3 and T4 secretion
B) stimulates iodide trapping by thyroid follicle cells
C) increases cyclic AMP concentration within thyroid follicle cells
D) stimulates T3 and T4 secretion
E) stimulates pinocytosis of colloid by thyroid follicle cells
A) inhibits T3 and T4 secretion
B) stimulates iodide trapping by thyroid follicle cells
C) increases cyclic AMP concentration within thyroid follicle cells
D) stimulates T3 and T4 secretion
E) stimulates pinocytosis of colloid by thyroid follicle cells
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64
The primary function of ADH is to
A) decrease blood pressure.
B) increase digestive absorption.
C) delay urination.
D) decrease the amount of water lost at the kidneys.
E) increase the amount of sodium lost at the kidneys.
A) decrease blood pressure.
B) increase digestive absorption.
C) delay urination.
D) decrease the amount of water lost at the kidneys.
E) increase the amount of sodium lost at the kidneys.
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65
The hormone produced by the pars intermedia of the adenohypophysis during early childhood is
A) ACTH.
B) FSH.
C) TSH.
D) ADH.
E) MSH.
A) ACTH.
B) FSH.
C) TSH.
D) ADH.
E) MSH.
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66
Shelly has a hormone- secreting tumor of the suprarenal gland. The tumor is causing her to have a deep voice, to grow extensive body hair, and to stop menstruating. This tumor probably involves cells of the
A) zona glomerulosa.
B) zona fasciculata.
C) suprarenal medulla.
D) zona reticularis.
E) pars intermedia.
A) zona glomerulosa.
B) zona fasciculata.
C) suprarenal medulla.
D) zona reticularis.
E) pars intermedia.
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67
Melanocyte- stimulating hormone MSH) is secreted by the human pars intermedia
A) during pregnancy.
B) during fetal development.
C) in some disease processes.
D) in very young children.
E) all of the above
A) during pregnancy.
B) during fetal development.
C) in some disease processes.
D) in very young children.
E) all of the above
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68
The pituitary hormone that stimulates milk production by the mammary glands is
A) growth hormone.
B) FSH.
C) TSH.
D) ACTH.
E) prolactin.
A) growth hormone.
B) FSH.
C) TSH.
D) ACTH.
E) prolactin.
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69
Which of the following hormones may lead to acromegaly if hypersecreted after closure of the epiphyseal plates?
A) cortisol
B) growth hormone
C) insulin
D) parathyroid hormone
E) epinephrine
A) cortisol
B) growth hormone
C) insulin
D) parathyroid hormone
E) epinephrine
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70

Use Figure 16- 1 to answer the following questions:
Identify the hormone labeled "13."
A) LH
B) estrogen
C) progesterone
D) oxytocin
E) testosterone
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71

Use Figure 16- 1 to answer the following questions:
During the alarm phase of the general adaptation syndrome GAS) there is
A) mobilization of energy reserves.
B) increased urine release.
C) decreased mental alertness.
D) decreased blood flow to skeletal muscles and skin.
E) decreased rate of respiration.
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72
The term used to describe excess production of urine is
A) polydipsia.
B) hematuria.
C) polyuria.
D) glycosuria.
E) none of the above
A) polydipsia.
B) hematuria.
C) polyuria.
D) glycosuria.
E) none of the above
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73
All of the following are true of steroid hormones, except that they
A) are lipids.
B) are derived from cholesterol.
C) are produced by reproductive glands.
D) are produced by the suprarenal medulla.
E) bind to receptors within the cell.
A) are lipids.
B) are derived from cholesterol.
C) are produced by reproductive glands.
D) are produced by the suprarenal medulla.
E) bind to receptors within the cell.
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74
An activated G protein can trigger
A) the opening of calcium ion channels in the membrane.
B) the production of diacylglycerol.
C) the release of calcium ions from intracellular stores.
D) a fall in cAMP levels.
E) all of the above
A) the opening of calcium ion channels in the membrane.
B) the production of diacylglycerol.
C) the release of calcium ions from intracellular stores.
D) a fall in cAMP levels.
E) all of the above
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75
Peptide hormones are
A) produced by the suprarenal glands.
B) composed of amino acids.
C) chemically related to cholesterol.
D) lipids.
E) derived from the amino acid tyrosine.
A) produced by the suprarenal glands.
B) composed of amino acids.
C) chemically related to cholesterol.
D) lipids.
E) derived from the amino acid tyrosine.
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76
The posterior pituitary gland secretes
A) ADH.
B) MSH.
C) TSH.
D) FSH.
E) ACTH.
A) ADH.
B) MSH.
C) TSH.
D) FSH.
E) ACTH.
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77
The pituitary hormone that promotes egg development in ovaries and sperm development in testes is
A) FSH.
B) LH.
C) TSH.
D) GH.
E) ACTH.
A) FSH.
B) LH.
C) TSH.
D) GH.
E) ACTH.
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78
The hormone that opposes the release of FSH in both males and females is
A) aldosterone.
B) testosterone.
C) LH.
D) somatostatin.
E) inhibin.
A) aldosterone.
B) testosterone.
C) LH.
D) somatostatin.
E) inhibin.
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79
The hormone that dominates during the alarm phase of the general adaptation syndrome GAS) is
A) aldosterone.
B) testosterone.
C) cortisol.
D) epinephrine.
E) thyroid hormone.
A) aldosterone.
B) testosterone.
C) cortisol.
D) epinephrine.
E) thyroid hormone.
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80
Cells can respond to _ hormones) at the same time.
A) only one
B) one or two
C) three or less
D) many
A) only one
B) one or two
C) three or less
D) many
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