Deck 5: Non-Mendelian Inheritance

Question 1

Where is extra nuclear DNA located in mammalian cells?

A) Endoplasmic reticulum
B) Mitochondria
C) Ribosome
D) Plasma membrane

Answer 1

B

Question 2

What is the molecular mechanism for imprinting a gene?

A) Acetylation
B) Nitration
C) Phosphorylation
D) Methylation

Answer 2

D

Question 3

Where does erasure and imprinting occur?

A) Nurse cells
B) Sperm cells
C) Oocytes
D) Somatic cells
E) More than one of the answers are correct

Answer 3

E

Question 4

Who is largely responsible for proposing the endosymbiosis theory?

A) Schimper, Wallin, Margulis
B) Lyon, Margulis, Schimper
C) Schimper, Wallin, Barr
D) Barr, Lyon, Margulis

Question 5

What gene is encoded in the Xic?

A) Xce
B) Xist
C) TsiX

Question 6

What encodes the toxin paramecin in Paramecia Aurelia?

A) MtDNA
B) CpDNA
C) Nuclear DNA
D) Kappa particles

Question 7

Who originally identified a highly condensed structure in the interphase of nuclei?

A) Lyon
B) Barr
C) Ohno
D) None of the answers are correct

Question 8

In the Igf-2 allele, which chromosome is imprinted? Which is expressed?

A) Paternal, paternal
B) Paternal, maternal
C) Maternal, paternal
D) Maternal, maternal

Question 9

What is thought to be the origin of mitochondria? Of chloroplasts?

A) Cyan bacteria/purple bacteria
B) Purple bacteria/fungus
C) Purple bacteria/cyanobacteria
D) Algae/cyanobacteria

Question 10

What is a disease associated with extra nuclear inheritance?

A) Angelman Syndrome
B) Prader-Willi Syndrome
C) LHON
D) Muscular Dystrophy

Question 11

What genes appear to be controlled by the Xce?

A) Xist and Tsix
B) Xist
C) TsiX

Question 12

Epigenic inheritance may occur at which of the following stages?

A) Oogenesis
B) Spermatogenesis
C) Embryogenesis
D) All of the answers are correct

Question 13

What type of inheritance is observed with extra nuclear DNA?

A) Mendelian inheritance
B) Sex-linked inheritance
C) Paternal inheritance
D) None of the answers are correct

Question 14

What are some diseases associated with imprinting?

A) Angelman Syndrome
B) LHON
C) Alzheimer's Disease
D) All of the answers are correct

Question 15

Both parents usually imprint the same gene.

Question 16

Most imprinted genes are silenced. What is one exception to this rule?

A) H19
B) Igf-2
C) UBE3A
D) SNRPN

Question 17

Which of the following is primarily responsible for the maternal effect?

A) Sperm cells
B) Oocytes
C) Nurse cells
D) Placenta

Question 18

In the gene that affects snail coiling, the is responsible for the phenotype of the offspring.

A) Mother's phenotype
B) Father's phenotype
C) Mother's genotype
D) Father's genotype

Question 19

Expression of would inhibit X-inactivation.

A) Xic
B) Xist
C) TsiX
D) All of the answers are correct
E) None of the answers are correct

Question 20

What gene is most responsible for X-inactivation?

A) Xic
B) Xist
C) TsiX
D) Xce

Question 21

The inheritance of leaf pigmentation in the four-o'clock plant Mirabilis jalapa is an example of .

A) Maternal effect
B) Maternal inheritance
C) Epigenic inheritance
D) Imprinting
E) None of the answers are correct

Question 22

mtDNA stands for and cpDNA stands for .

A) extranuclear DNA, cytoplasmic DNA
B) maternal DNA, paternal DNA
C) marked DNA, copied DNA
D) nuclear, cytoplasmic
E) mitochondrial DNA, chloroplast DNA

Question 23

How many Barr bodies would an individual with a XXY genotype possess?

A) 0
B) 1
C) 2
D) None of the answers are correct

Question 24

The coat color of calico cats is a result of .

A) Maternal inheritance
B) X-inactivation
C) Imprinting
D) Extra nuclear inheritance

Question 25

A symbiotic relationship where one organism lives inside another species is called .

A) cytoplasmic inheritance
B) heteroplasmy
C) paternal leakage
D) endosymbiosis
E) None of the answers are correct

Question 26

Differentially methylated domains (DMDs) are associated with which of the following?

A) X-inactivation
B) Genomic imprinting
C) Maternal inheritance
D) Extra nuclear inheritance
E) All of the answers are correct

Question 27

Chlamydomonas was the used as the model organism for the study of .

A) Chloroplast inheritance
B) Mitochondrial inheritance
C) Genomic imprinting
D) Methylation of DNA
E) None of the answers are correct

Question 28

mtDNA contains all of the genes necessary for the complete function of mitochondrial
metabolism.

Question 29

A modification that occurs to a nuclear gene that alters gene expression, but not permanently, is called inheritance.

A) extranuclear
B) cytoplasmic
C) maternal effect
D) epigenetic
E) nuclear

Question 30

The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called .

A) extranuclear (or cytoplasmic) inheritance
B) maternal effect
C) imprinting
D) nuclear
E) epigenetic

Question 31

Which of the following is true regarding mtDNA?

A) It is around 17,000 bp in length
B) It is a circular chromosome
C) Multiple copies exist in each mitochondria
D) It mostly contains rRNA and tRNA genes
E) All of the answers are correct

Question 32

Dosage compensation offsets the problems associated with differences in the number of chromosomes in many species.

A) cytoplasmic
B) autosome
C) sex
D) extranuclear
E) mitochondrial

Question 33

In maternal effect, the of the mother determines the of the offspring.

A) phenotype, genotype
B) genotype, phenotype
C) rRNA, tRNA
D) imprinting, genotype
E) None of the answers are correct

Question 34

If the sperm cell contributes mitochondria to the oocyte, it is called .

A) paternal leakage
B) maternal leakage
C) paternal inheritance
D) mitochondria
E) imprinting

Question 35

Monoallelic expression is associated with which of the following?

A) X-inactivation
B) Genomic imprinting
C) Maternal inheritance
D) Extra nuclear inheritance

Question 36

The Lyon hypothesis attempts to explain the molecular mechanism of .

A) X-inactivation
B) Genomic imprinting
C) Maternal inheritance
D) Extra nuclear inheritance

Question 37

Heteroplasmy is associated with inheritance patterns involving

A) nuclear
B) paternal DNA
C) chloroplasts
D) mitochondria
E) imprinted

Question 38

cpDNA contains which of the following types of genes?

A) rRNA
B) tRNA
C) Genes for photosynthetic pathways
D) All of the answers are correct
E) Both rRNA and tRNA