Deck 1: Substance Use Disorder and Addiction: Basic and Brief Psychopharmacological and Neuropsychological Review

Question 1

Cocaine is NOT associated with which neurotransmitter?

A) Serotonin
B) Dopamine
C) Acetylcholine
D) Norepinphrine

Answer 1

C

Question 2

The time a substance takes to make it into general circulation is:

A) distribution half-life
B) therapeutic half-life
C) elimination half-life
D) administration half-life

Answer 2

A

Question 3

As per Soyka et al. (2011), Opiates impair cognitive functioning in the following areas:

A) frontal cortex
B) cerebellum
C) hippocampus
D) both a and c

Answer 3

D

Question 4

This type of half-life focuses on the time it takes for the concentration of a substance to decline and is used to determine if a substance (such as benzodiazepines) are short, medium, or long acting.

A) Alpha half-life
B) Beta half-life
C) Elimination half-life
D) Therapeutic half-life

Question 5

As per Brickman's Model, the applicability of the 12-Step Philosophy is most associated with an area that is termed:

A) moral
B) spiritual
C) compensatory
D) disease

Question 6

A set amount of a substance being biotransformed per each hour is indicative of what type of biotransformation?

A) Zero-order
B) First-order
C) Depends on the substance
D) Depends on the administration

Question 7

Methamphetamine users show symptoms consistent with frontal systems dysfunction; these symptoms include:

A) apathy
B) impulsivity
C) sensation seeking
D) all of the above

Question 8

This type of administration is associated with snorting of a substance.

A) Transdermal
B) Intranasal
C) Parenteral
D) Enteral

Question 9

The time the body takes to eliminate 50% of a single dose of the substance ingested:

A) distribution half-life
B) therapeutic half-life
C) elimination half-life
D) administration half-life

Question 10

This type of administration occurs orally.

A) Transdermal
B) Intranasal
C) Parenteral
D) Enteral

Question 11

This type of compound must bind with other molecules in order to move throughout the body.

A) Lipid-soluble
B) Water-soluble
C) Both a and b
D) Neither a nor b

Question 12

A set percentage of a substance being biotransformed per each hour is indicative of what type of biotransformation?

A) Zero-order
B) First-order
C) Depends on the substance
D) Depends on the administration

Question 13

Wernicke-Korsakoff Syndrome (WKS) is typically associated with what substance?

A) Cocaine
B) Heroin
C) Alcohol
D) Methamphetamine

Question 14

As per Brickman's Model, the addictions counselor use of neuropsychology to account for the client responsibility related to addiction development and relapse is termed:

A) moral
B) spiritual
C) compensatory
D) disease

Question 15

This type of administration involves injecting and "skin popping."

A) Transdermal
B) Intranasal
C) Parenteral
D) Enteral

Question 16

This type of compound mixes easily with blood plasma and moves easily throughout the body.

A) Lipid-soluble
B) Water-soluble
C) Both a and b
D) Neither a nor b

Question 17

As per Brickman's Model, the belief that the individual is responsible for their addiction development and their relapse is termed:

A) moral
B) spiritual
C) compensatory
D) disease

Question 18

This type of administration is via absorption through the skin.

A) Transdermal
B) Intranasal
C) Parenteral
D) Enteral

Question 19

In Cocaine users, increased linkages to the hippocampus and amygdala may explain how intense craving is linked with:

A) vulnerability to drug-related stimuli
B) impaired judgment
C) cocaine-associated memories
D) all of the above

Question 20

The time the body takes to inactivate 50% of the substance ingested:

A) distribution half-life
B) therapeutic half-life
C) elimination half-life
D) administration half-life

Question 21

Glutamate increases neuron activity.

Question 22

Methamphetamine is associated with multiple neurotransmitters.

Question 23

MDMA is associated with Dopamine.

Question 24

Explain some of the common neurocognitive deficits in those with substance use disorder (SUD) and how they impede traditional SUD treatment.

Question 25

Nicotine is associated with Acetylcholine.

Question 26

Describe the different types of half-life and their importance regarding substance use.

Question 27

Briefly explain using biotransformation how/why someone gets drunk on alcohol.

Question 28

GABA increases neuron activity.