Deck 8: DNA Detective: Complex Patterns of Inheritance and DNA Fingerprinting
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Deck 8: DNA Detective: Complex Patterns of Inheritance and DNA Fingerprinting
1
Phenotypic features that are coded for by several genes, such as eye color in humans, are called
A) linked.
B) polytrophic.
C) polygenic.
D) codominant.
A) linked.
B) polytrophic.
C) polygenic.
D) codominant.
C
2
A person who is homozygous recessive for both blood type alleles has type ________ blood.
A) A
B) B
C) AB
D) O
A) A
B) B
C) AB
D) O
D
3
When does codominance occur?
A) both of the alleles in a heterozygote are expressed phenotypically in an individual
B) expression of two different alleles alternates from one generation to the next
C) a heterozygote expresses an intermediate phenotype
D) offspring exhibit several different phenotypic expressions of a single trait
A) both of the alleles in a heterozygote are expressed phenotypically in an individual
B) expression of two different alleles alternates from one generation to the next
C) a heterozygote expresses an intermediate phenotype
D) offspring exhibit several different phenotypic expressions of a single trait
A
4
A child with type O blood could not have a parent with type ________ blood.
A) A
B) B
C) AB
D) O
A) A
B) B
C) AB
D) O
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5
The alleles responsible for the ABO blood types of humans are an example of ________ alleles.
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6
If a blue-colored flower crossed with a white-colored flower produced light blue-colored flower offspring, then it's most likely a case of
A) incomplete dominance.
B) codominance.
C) independent assortment.
D) sex linkage.
A) incomplete dominance.
B) codominance.
C) independent assortment.
D) sex linkage.
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7
A woman with type AB blood has sugars on what percent of her red blood cells?
A) 0%
B) 25%
C) 50%
D) 100%
A) 0%
B) 25%
C) 50%
D) 100%
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8
There are NO sugars on the surface of any of the red blood cells for which blood type?
A) type A
B) type B
C) type AB
D) type O
A) type A
B) type B
C) type AB
D) type O
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9
The AB blood type, in which both A and B alleles are expressed, is an example of
A) incomplete dominance.
B) codominance.
C) independent assortment.
D) sex linkage.
A) incomplete dominance.
B) codominance.
C) independent assortment.
D) sex linkage.
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10
If one person in a population has two different alleles of a particular gene and it's known that other people in the population have yet another different allele of this gene, then this is an example of
A) codominance.
B) pleiotropy.
C) incomplete dominance.
D) multiple allelism.
A) codominance.
B) pleiotropy.
C) incomplete dominance.
D) multiple allelism.
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11
The pattern of inheritance for Rh factor is best described as ________.
A) incomplete dominance.
B) codominance.
C) dominant-recessive.
D) sex linkage.
A) incomplete dominance.
B) codominance.
C) dominant-recessive.
D) sex linkage.
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12
Type AB blood is a result of
A) polygenic inheritance.
B) simple dominance.
C) codominance.
D) sex-linked recessive inheritance.
A) polygenic inheritance.
B) simple dominance.
C) codominance.
D) sex-linked recessive inheritance.
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13
When the phenotype of a heterozygote is intermediate between both homozygotes, the pattern of inheritance is ________.
A) incomplete dominance
B) codominance
C) independent assortment
D) sex linkage
A) incomplete dominance
B) codominance
C) independent assortment
D) sex linkage
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14
A woman with type A blood has the alleles I? and i. Her blood type is a result of
A) polygenic inheritance.
B) simple dominance.
C) codominance.
D) sex-linked recessive inheritance.
A) polygenic inheritance.
B) simple dominance.
C) codominance.
D) sex-linked recessive inheritance.
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15
People with the same blood type
A) are always unrelated.
B) are always related.
C) may or may not be related.
D) always have both alleles in common but are not necessarily related.
A) are always unrelated.
B) are always related.
C) may or may not be related.
D) always have both alleles in common but are not necessarily related.
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16
Which statement about the inheritance of blood types in humans is correct?
A) Alleles I? and i are dominant to the allele I?.
B) Alleles I? and i are dominant to the allele I?.
C) Alleles I? and I? are dominant to the allele i.
D) Alleles I?, ?? and i are codominant.
A) Alleles I? and i are dominant to the allele I?.
B) Alleles I? and i are dominant to the allele I?.
C) Alleles I? and I? are dominant to the allele i.
D) Alleles I?, ?? and i are codominant.
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17
Multiple ________ occurs in the ABO blood system, where there are three distinct alleles in human populations.
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18
A child with the genotype I?? has type ________ blood.
A) A
B) B
C) AB
D) O
A) A
B) B
C) AB
D) O
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19
Which of the following individuals doesn't have the Rh factor on their red blood cells?
A) Rh? Rh?
B) Rh? Rh?
C) Rh? Rh?
D) Rh? Rh?
A) Rh? Rh?
B) Rh? Rh?
C) Rh? Rh?
D) Rh? Rh?
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20
In human ABO blood types, the alleles for A and B are said to be ________ because they're both expressed.
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21
Females inherit two X chromosomes and males inherit one X chromosome. However, there is not a double dose of X gene products in females because of
A) nondisjunction.
B) X- linkage.
C) the SRY gene.
D) X inactivation in females.
A) nondisjunction.
B) X- linkage.
C) the SRY gene.
D) X inactivation in females.
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22
A patient with which blood type can receive blood from any donor?
A) type A
B) type B
C) type AB
D) type O
A) type A
B) type B
C) type AB
D) type O
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23
What is the most common blood type in the U.S. population?
A) type O?
B) type B?
C) type AB?
D) type O?
A) type O?
B) type B?
C) type AB?
D) type O?
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24
A person with hemophilia lacks the pleiotropic gene that codes for the protein called clotting factor VIII. This means that he or she will
A) have only the symptom of lack of blood clotting (bleeding).
B) always have the same symptoms as other hemophiliacs.
C) have many other symptoms in addition to excessive bleeding.
D) always have neurological problems.
A) have only the symptom of lack of blood clotting (bleeding).
B) always have the same symptoms as other hemophiliacs.
C) have many other symptoms in addition to excessive bleeding.
D) always have neurological problems.
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25
Hemophilia is a genetic disease that has plagued the royal houses of Europe. The disease allele is recessive and X-linked. Queen Victoria was a carrier, and her granddaughter Alexandra married Nicholas II, the last czar of imperial Russia. Alexandra was a carrier for hemophilia; Nicholas was normal. Their son, Alexis, was afflicted with the disease. Alexis and his four sisters were killed in 1917. It's most likely that
A) none of the four sisters carried the hemophilia allele.
B) at least one of the sisters was a carrier of the allele.
C) all four sisters were carriers of the hemophilia allele.
D) at least one of the sisters had hemophilia like Alexis.
A) none of the four sisters carried the hemophilia allele.
B) at least one of the sisters was a carrier of the allele.
C) all four sisters were carriers of the hemophilia allele.
D) at least one of the sisters had hemophilia like Alexis.
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26
A patient with which blood type can donate blood to anyone?
A) type A
B) type B
C) type AB
D) type O
A) type A
B) type B
C) type AB
D) type O
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27
A woman with type A blood and a man with type B blood have a baby with type O blood. What are the genotypes of the woman and the man?
A) I?? and I??
B) I??? and I??
C) I?? and I???
D) I??? and I???
A) I?? and I??
B) I??? and I??
C) I?? and I???
D) I??? and I???
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28
In humans, the allele for red-green color blindness is X-linked and recessive (X?; the dominant allele is called X?). A man with normal color vision marries a color-blind woman who gives birth to a color-blind daughter. From this, we can tell that
A) the woman is X?X?.
B) the man must be a carrier for the color blindness allele.
C) the daughter must be heterozygous.
D) the man is probably NOT the father of the daughter.
A) the woman is X?X?.
B) the man must be a carrier for the color blindness allele.
C) the daughter must be heterozygous.
D) the man is probably NOT the father of the daughter.
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29
When a dominant allele has different effects between heterozygous individuals and homozygous individuals, the phenomenon is called
A) codominance.
B) continuous variation.
C) incomplete dominance.
D) polygenic inheritance.
A) codominance.
B) continuous variation.
C) incomplete dominance.
D) polygenic inheritance.
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30
A woman with type AB blood and a man with type O blood have a child. Which type of blood could the child have?
A) type A or type O
B) type B or type O
C) type AB or type O
D) type A or type B
A) type A or type O
B) type B or type O
C) type AB or type O
D) type A or type B
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31
Describing a person as having hemophilia is to indicate his or her
A) genotype.
B) phenotype.
C) genetic code.
D) number of chromosomes.
A) genotype.
B) phenotype.
C) genetic code.
D) number of chromosomes.
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32
Hemophilia is an X-linked recessive allele causing a blood disorder. What are the chances that a daughter of a normal man and a woman, who is heterozygous for the disease, will have hemophilia?
A) 0%
B) 25%
C) 75%
D) 100%
A) 0%
B) 25%
C) 75%
D) 100%
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33
A man who carries a harmful allele for a sex-linked gene (on the X chromosome)will pass the allele on to
A) all of his daughters.
B) only half of his daughters.
C) only half of his sons.
D) all of his children.
A) all of his daughters.
B) only half of his daughters.
C) only half of his sons.
D) all of his children.
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34
The ability of a gene to cause multiple effects on a phenotype is called
A) pleiotropy.
B) codominance.
C) polygenic inheritance.
D) continuous variation.
A) pleiotropy.
B) codominance.
C) polygenic inheritance.
D) continuous variation.
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35
Sex-linked traits can be expressed in
A) males only.
B) females only.
C) either males or females.
D) carriers only.
A) males only.
B) females only.
C) either males or females.
D) carriers only.
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36
Hemophiliacs have blood that does not coagulate well, and they often die at a young age. The disease allele is recessive and X-linked. Which of the following is the BEST prediction about the offspring of a hemophiliac male and a nonhemophiliac female who is a carrier for the disease?
A) All children would be hemophiliac.
B) All females would be hemophiliac.
C) All males would be hemophiliac.
D) Some males and females could be hemophiliac.
A) All children would be hemophiliac.
B) All females would be hemophiliac.
C) All males would be hemophiliac.
D) Some males and females could be hemophiliac.
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37
A normal individual who is a carrier for an X-linked trait such as hemophilia
A) is always female.
B) is homozygous for the recessive condition.
C) shows the recessive phenotype.
D) cannot have daughters who have the allele.
A) is always female.
B) is homozygous for the recessive condition.
C) shows the recessive phenotype.
D) cannot have daughters who have the allele.
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38
In addition to excessive bleeding, persons with hemophilia may have excessive bruising, pain and swelling in the joints, vision loss, anemia, or neurological problems. This is a result of the effects of a single gene loss and is called
A) codominance.
B) multiple allelism.
C) pleiotropy.
D) environmental effects.
A) codominance.
B) multiple allelism.
C) pleiotropy.
D) environmental effects.
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39
Human bone size and structure are a result of the environment and
A) polygenic inheritance.
B) codominance.
C) simple dominance.
D) sex-linked recessive inheritance.
A) polygenic inheritance.
B) codominance.
C) simple dominance.
D) sex-linked recessive inheritance.
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40
Y-linked genes include a gene that produces hairy ears. A male with hairy ears should pass this trait
A) only to his sons.
B) only to his daughters.
C) only to his grandsons.
D) to all his children if the mother is a carrier.
A) only to his sons.
B) only to his daughters.
C) only to his grandsons.
D) to all his children if the mother is a carrier.
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41
A human sperm cell receives autosomes and
A) an X chromosome always.
B) either an X or a Y chromosome.
C) a Y chromosome always.
D) both an X and a Y chromosome.
A) an X chromosome always.
B) either an X or a Y chromosome.
C) a Y chromosome always.
D) both an X and a Y chromosome.
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42
Queen Elizabeth II of England is a descendant of Edward VII of England, who was the son of Queen Victoria. Edward VII did not have hemophilia. Prince Philip, who is married to Queen Elizabeth II, is a descendant of Alice, the daughter of Queen Victoria. Alice was a carrier of hemophilia. However, Prince Philip does not have hemophilia. What can you assume about the children of Queen Elizabeth II and Prince Philip?
A) None of the children could have the hemophilia allele.
B) Only the sons could have the hemophilia allele.
C) Only their daughter could have the hemophilia allele.
D) Any one of the children could have the hemophilia allele.
A) None of the children could have the hemophilia allele.
B) Only the sons could have the hemophilia allele.
C) Only their daughter could have the hemophilia allele.
D) Any one of the children could have the hemophilia allele.
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43
A DNA fingerprint of a suspect doesn't match a DNA fingerprint from a blood sample taken at a crime scene. What can you conclude?
A) The suspect was never at the crime scene.
B) The blood sample was probably degraded or destroyed in some way.
C) There is no DNA in a blood sample.
D) The blood came from a different person, but the suspect may have been there.
A) The suspect was never at the crime scene.
B) The blood sample was probably degraded or destroyed in some way.
C) There is no DNA in a blood sample.
D) The blood came from a different person, but the suspect may have been there.
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44
The allele for orange fur in cats is X?, while the allele for black fur is X?. You adopt a tortoiseshell kitten (with orange and black fur). When you take the kitten to the vet, you find out that it is a male. What is the genotype of this kitten?
A) X?Y
B) X?X?
C) X?Y
D) X?X?Y
A) X?Y
B) X?X?
C) X?Y
D) X?X?Y
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45
Hemophilia is an X-linked recessive trait in humans. If phenotypically normal parents have children without hemophilia, pedigree analysis
A) could demonstrate that neither parent carries the hemophiliac allele.
B) would show that none of their children is a carrier of the hemophilia allele.
C) would show that none of their children could have hemophiliac children.
D) would not be able to show the exact genotypes of the parents or children.
A) could demonstrate that neither parent carries the hemophiliac allele.
B) would show that none of their children is a carrier of the hemophilia allele.
C) would show that none of their children could have hemophiliac children.
D) would not be able to show the exact genotypes of the parents or children.
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46

England's Prince Philip was found to have DNA sequences that matched ________.
A) both the tsar and the tsarina
B) the tsar but not the tsarina
C) the tsarina but not the tsar
D) neither the tsar nor the tsarina
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47
VNTR stands for
A) variable number tandem repeats.
B) varied nucleotides to repeat.
C) volumes of nucleotide tandem repeats.
D) variation of nucleotide terminal repeats.
A) variable number tandem repeats.
B) varied nucleotides to repeat.
C) volumes of nucleotide tandem repeats.
D) variation of nucleotide terminal repeats.
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48
DNA fragments must be denatured during the polymerase chain reaction due to which of the following?
A) Taq polymerase breaks down when heated
B) the repeated gene sequences are not present in double-stranded DNA
C) the primer must bind to a single-stranded template to synthesize double-stranded DNA
D) VNTRs have DNA sequences that vary in number
A) Taq polymerase breaks down when heated
B) the repeated gene sequences are not present in double-stranded DNA
C) the primer must bind to a single-stranded template to synthesize double-stranded DNA
D) VNTRs have DNA sequences that vary in number
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49
Because the bones thought to belong to the Romanov family were highly decayed, scientists determined the gender of each deceased individual by utilizing which type of analysis?
A) pelvic bone analysis only
B) DNA analysis of material that is specific to the Y chromosome
C) DNA analysis of material that is specific to the X chromosome
D) both pelvic bone analysis and DNA analysis
A) pelvic bone analysis only
B) DNA analysis of material that is specific to the Y chromosome
C) DNA analysis of material that is specific to the X chromosome
D) both pelvic bone analysis and DNA analysis
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50
What is responsible for the tortoiseshell phenotype in some female cats?
A) codominance
B) X inactivation
C) incomplete dominance
D) pleiotropy
A) codominance
B) X inactivation
C) incomplete dominance
D) pleiotropy
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51
A family tree that is used to follow human matings that have already occurred is a
A) test cross.
B) karyotype.
C) sex-linked record.
D) pedigree.
A) test cross.
B) karyotype.
C) sex-linked record.
D) pedigree.
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52
Polydactyly is a dominant trait. A male who has polydactyly would be represented by what symbol on a pedigree chart?
A) a half-shaded square
B) a shaded square
C) a half-shaded circle
D) a clear circle
A) a half-shaded square
B) a shaded square
C) a half-shaded circle
D) a clear circle
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53
What does a half-shaded circle represent on a pedigree chart?
A) a female carrier
B) a female who does not have an allele for the genetic disorder represented
C) a male who is affected by the genetic disorder represented
D) a male carrier
A) a female carrier
B) a female who does not have an allele for the genetic disorder represented
C) a male who is affected by the genetic disorder represented
D) a male carrier
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54
In humans, the sex of the offspring is ordinarily determined by the
A) autosomes carried by the egg cell.
B) autosomes carried by the sperm cell.
C) sex chromosome carried by the egg cell.
D) sex chromosome carried by the sperm cell.
A) autosomes carried by the egg cell.
B) autosomes carried by the sperm cell.
C) sex chromosome carried by the egg cell.
D) sex chromosome carried by the sperm cell.
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55
On a pedigree chart, a son who is affected by a genetic disorder would be represented by which symbol?
A) a shaded circle
B) a clear circle
C) a shaded square
D) a clear square
A) a shaded circle
B) a clear circle
C) a shaded square
D) a clear square
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56

A pedigree of the British royal family shows that Queen Victoria was the first in the royal line to have
A) hemophilia.
B) all of her children born with hemophilia.
C) a mutation in a blood-clotting gene.
D) inherited a mutation in a blood-clotting allele.
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57
Which of the following types of forensic evidence was available for scientists studying the case of the Romanovs?
A) fingerprint
B) toxicology
C) DNA
D) footprint
A) fingerprint
B) toxicology
C) DNA
D) footprint
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58
Humans possess
A) 2 pairs of sex chromosomes and 46 pairs of autosomes.
B) 2 pairs of sex chromosomes and 22 pairs of autosomes.
C) 1 pair of sex chromosomes and 46 pairs of autosomes.
D) 1 pair of sex chromosomes and 22 pairs of autosomes.
A) 2 pairs of sex chromosomes and 46 pairs of autosomes.
B) 2 pairs of sex chromosomes and 22 pairs of autosomes.
C) 1 pair of sex chromosomes and 46 pairs of autosomes.
D) 1 pair of sex chromosomes and 22 pairs of autosomes.
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59

What are the chances that a hemophiliac male and an unaffected female could have a baby that is a hemophiliac male?
A) 0%
B) 25%
C) 50%
D) 75%
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60
When comparing the DNA fingerprints of a parent and child, the parent's DNA fingerprint will have which of the following genetic traits?
A) all of the DNA bands that the child has
B) more than half of the DNA bands that the child has
C) DNA bands that match those in the child's fingerprint and that aren't from the other parent
D) DNA bands that are very close to bands found in the child but do not match precisely
A) all of the DNA bands that the child has
B) more than half of the DNA bands that the child has
C) DNA bands that match those in the child's fingerprint and that aren't from the other parent
D) DNA bands that are very close to bands found in the child but do not match precisely
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61
DNA moves in an electric field toward
A) a positive charge.
B) a negative charge.
C) the highest concentration of gel.
D) the smallest sized DNA fragments.
A) a positive charge.
B) a negative charge.
C) the highest concentration of gel.
D) the smallest sized DNA fragments.
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62
VNTRs are
A) fragments of DNA that have been denatured.
B) nucleotide sequences that correspond to specific genes.
C) distinct nucleotide sequences that everyone has in different numbers.
D) nucleotide sequences that are different in different individuals.
A) fragments of DNA that have been denatured.
B) nucleotide sequences that correspond to specific genes.
C) distinct nucleotide sequences that everyone has in different numbers.
D) nucleotide sequences that are different in different individuals.
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63
The enzyme used to synthesize daughter strands of DNA during PCR is called a ________.
A) replicase.
B) DNA polymerase.
C) RNA polymerase.
D) Taq polymerase.
A) replicase.
B) DNA polymerase.
C) RNA polymerase.
D) Taq polymerase.
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64
Different persons have different DNA fingerprints because
A) they have completely different kinds of VNTRs.
B) they have different numbers of the same VNTR.
C) PCR generates some sequences more than other sequences.
D) restriction enzymes may not cut some VNTRs if adjacent to different DNA sequences.
A) they have completely different kinds of VNTRs.
B) they have different numbers of the same VNTR.
C) PCR generates some sequences more than other sequences.
D) restriction enzymes may not cut some VNTRs if adjacent to different DNA sequences.
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65
What does each different band on a DNA fingerprint represent?
A) gene
B) VNTR site
C) allele
D) pleiotropy
A) gene
B) VNTR site
C) allele
D) pleiotropy
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66
In DNA fingerprinting, amplified fragments of DNA are separated from one another by which process?
A) filtering
B) chromatography
C) electrophoresis
D) PCR (polymerase chain reaction)
A) filtering
B) chromatography
C) electrophoresis
D) PCR (polymerase chain reaction)
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67
What is the function of Taq polymerase?
A) to denature DNA so its strands separate
B) to bond to complementary DNA
C) to free nucleotides from a DNA strand
D) to use primers to initiate DNA synthesis
A) to denature DNA so its strands separate
B) to bond to complementary DNA
C) to free nucleotides from a DNA strand
D) to use primers to initiate DNA synthesis
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68
What is one reason why the polymerase chain reaction (PCR)is so useful for DNA fingerprinting?
A) It can produce millions of copies from tiny amounts of DNA.
B) It can be used to compare DNA from different individuals.
C) It can identify the complete sequence of a gene.
D) It can allow scientists to visualize the DNA of specific individuals.
A) It can produce millions of copies from tiny amounts of DNA.
B) It can be used to compare DNA from different individuals.
C) It can identify the complete sequence of a gene.
D) It can allow scientists to visualize the DNA of specific individuals.
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69
Gel electrophoresis separates DNA segments on the basis of their
A) weight.
B) length.
C) types of nucleotides.
D) complexity.
A) weight.
B) length.
C) types of nucleotides.
D) complexity.
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70
The polymerase chain reaction (PCR)is used to
A) analyze a person's fingerprints.
B) separate fragments of DNA.
C) make many copies of a small amount of DNA.
D) cut DNA into many small pieces.
A) analyze a person's fingerprints.
B) separate fragments of DNA.
C) make many copies of a small amount of DNA.
D) cut DNA into many small pieces.
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71
Which of the following is used to produce genetic fingerprints of people?
A) RNA polymerase
B) Punnett squares
C) pedigree analysis
D) VNTRs
A) RNA polymerase
B) Punnett squares
C) pedigree analysis
D) VNTRs
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