Deck 11: Muscle

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Question
Given what you know about the musculature of the respiratory system, what is the most likely explanation for why you can change your breathing rate at any time?

A) the smooth muscles of the respiratory tract can be consciously controlled, unlike like other involuntary systems in the body
B) breathing rate is achieved through skeletal muscles, which are under partial voluntary control
C) in addition to smooth muscles that allow for conscious control, there are likely skeletal muscles involved that can be consciously controlled
D) there are skeletal muscles involved in breathing that display smooth muscle-like autorhythmicity
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Question
The muscle action potential quickly spreads into the muscle fiber as it travels along the _____, which is an extension of the _____.

A) myofibril; sarcoplasm
B) myofibril; sarcoplasmic reticulum
C) transverse tubules; sarcolemma
D) transverse tubules; sarcoplasm
Question
The storage form of glucose that is present in muscles cells is known as ______.
Question
Calcium from the extracellular fluid is important for contraction of which type(s) of muscle?

A) cardiac only
B) cardiac and skeletal
C) cardiac and smooth
D) cardiac, skeletal and smooth
Question
Larry is stretching out his leg muscles before going for a run. Which property of muscle allows Larry to do this without hurting himself?

A) contractility
B) elasticity
C) electrical excitability
D) extensibility
Question
Which type(s) of muscle contraction is regulated by autonomic motor neurons?

A) cardiac only
B) cardiac and skeletal
C) cardiac and smooth
D) cardiac, skeletal and smooth
Question
After eating some questionable taco meat, your friend Joshua begins to throw up those risky tacos he ate only a few hours before. Which muscle function best explains why this might have occurred?

A) production of body movement
B) storage and movement of substances within the body
C) thermogenesis
D) stabilization of body position
Question
Which type(s) of muscle contraction can be regulated by acetylcholine?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
Question
Which muscle function explains why you get hot during strenuous exercise?

A) production of movement
B) involuntary stabilization
C) thermogenesis
D) moving substances within the body
Question
Which property of muscle allows the stretched muscles to go back to their original shape and size?

A) contractility
B) elasticity
C) electrical excitability
D) extensibility
Question
Which muscle property best explains the autorhythmicity of the heart?

A) electrical excitability
B) involuntary control
C) extensibility
D) contractility
Question
Which muscle property best explains how the heart generates your blood pressure?

A) elasticity
B) involuntary control
C) extensibility
D) contractility
Question
Which of the following muscle functions can explain why your head falls down when you begin to fall asleep during class?

A) production of body movement
B) storage and movement of substances within the body
C) thermogenesis
D) stabilization of body position
Question
Which of the following is the best explanation for why the statement "I can control my heart rate" is not entirely true?

A) It is not possible to consciously control other factors that affect heart rate, like breathing and physical activity, and so it is also not possible to consciously control heart muscle contractions.
B) It is possible to consciously control other factors that affect heart rate, like breathing and physical activity, but it is not possible to consciously control heart muscle contractions.
C) It is not possible to consciously control other factors that affect heart rate, like breathing and physical activity, but it is also possible to consciously control heart muscle contractions.
D) It is possible to consciously control other factors that affect heart rate, like breathing and physical activity, and it is possible to consciously control heart muscle contractions.
Question
Which type(s) of muscle can display(s) autorhythmicity?

A) cardiac only
B) cardiac and skeletal
C) cardiac and smooth
D) cardiac, skeletal and smooth
Question
Which type(s) of muscle contraction is regulated by somatic motor neurons?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
Question
Which type(s) of muscle have transverse tubules?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
Question
Sarcomeres are present in which type(s) of muscle?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
Question
Calcium from the sarcoplasmic reticulum is important for contraction of which type(s) of muscle?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
Question
Which type(s) of muscle contraction can be regulated by norepinephrine?

A) cardiac only
B) cardiac and skeletal
C) cardiac and smooth
D) cardiac, skeletal and smooth
Question
During a concentric muscle contraction, _______ moves along _______ toward the M line.

A) actin; myosin
B) myosin; actin
C) tropomyosin; actin
D) tropomyosin; troponin
Question
During an isotonic muscle contraction, what happens to the H zone?

A) it does not change
B) it gets longer
C) it gets shorter
D) it gets longer and shorter, successively
Question
Which of the following are the contractile proteins of muscle?

A) actin and myosin
B) dystrophin and actin
C) myosin and nebulin
D) tropomyosin and troponin
Question
Activation of nicotinic acetylcholine receptors on skeletal muscle cells most directly leads to a/an

A) action potential
B) end plate potential
C) autorhythmic potential
D) receptor potential
Question
During the depolarizing phase of a skeletal muscle action potential, ______ ions are moving _____ the cell and during the repolarizing phase _____ ions move _____ _____ the cell.
Question
Just like a neuronal action potential, a muscle action potential consists of a depolarizing phase caused by opening of voltage-gated sodium channels followed by a repolarizing phase due to opening of voltage-gated potassium channels and closing of voltage-gated sodium channels.
Question
Which muscle protein is responsible for attaching the M line to the Z line?

A) myosin
B) actin
C) titin
D) nebulin
Question
The A band corresponds to the full length of which component of the sarcomere?

A) thick filament
B) thin filament
C) titin filament
D) tropomyosin
Question
After a person or animal dies, the muscles of the body become very flaccid for a short period of time, before rigor mortis sets in. Which of the following is a possible explanation for why this brief state of flaccidity occurs?

A) Muscle cells become overexcited following death.
B) ATP is depleted and therefore there exists no energy for the contraction cycle.
C) Skeletal muscles require stimulation from the nervous system to contract, which ceases upon death.
D) Ca2+ leaks out of cells causing myosin to attach to actin.
Question
An end plate potential flows in one direction along a skeletal muscle fiber.
Question
Which molecule helps to anchor thin filaments to the ends of the sarcomere?

A) dystrophin
B) myomesin
C) nebulin
D) titin
Question
A somatic motor neuron releases _____ onto skeletal muscle to cause it to contract.
Question
What happens immediately after ATP attaches to myosin?

A) myosin head attaches to actin
B) myosin head detaches from actin
C) myosin head hydrolyzes ATP to ADP
D) myosin head pivots from 90o angle to 45o angle
Question
Certain pesticides inhibit acetylcholinesterase. What effects would this have on muscle fibers?

A) it would lead to increased muscle contractions
B) it would lead to increased muscle relaxation
C) it would lead to decreased muscle contractions
D) it would not change muscle fiber activity
Question
You are a scientist performing an experiment on some isolated skeletal muscle fibers. You observe that when you observe the muscle fibers under a microscope and apply a small amount of calcium, the fibers contract, but then after a short time they relax back to their original length. Which of the following is (are) possible explanation(s) for this observation?

A) The applied Ca2+ activates the muscle, but following the refractory period the Ca2+ loses its effect and the muscle relaxes.
B) The applied Ca2+ activates the muscle, but the muscle soon dephosphorylates its myosin and relaxes.
C) The applied Ca2+ at first activates the muscle, but then is pumped into the sarcoplasmic reticulum and is stored.
D) All of the choices are possible.
Question
Which molecule's activity is directly regulated by the presence and binding of calcium?

A) actin
B) myosin
C) tropomyosin
D) troponin
Question
What happens during the power stroke of the contraction cycle?

A) myosin head attaches to actin
B) myosin head detaches from actin
C) myosin head hydrolyzes ATP to ADP
D) myosin head pivots from 90o angle to 45o angle
Question
Which of the following are regulatory proteins of muscle?

A) actin and myosin
B) dystrophin and titin
C) myomesin and nebulin
D) tropomyosin and troponin
Question
Which molecule blocks the myosin-binding sites by wrapping around the thin filament?

A) actin
B) myosin
C) tropomyosin
D) troponin
Question
Which molecule has an ATP-binding site?

A) actin
B) myosin
C) tropomyosin
D) troponin
Question
A buildup of which of the following can lead to skeletal muscle fatigue.

A) ADP
B) creatine phosphate
C) ATP
D) oxygen
Question
The skeletal muscle action potential is MOST DIRECTLY important for which process?

A) activating the DHP receptor
B) activating the ryanodine receptor
C) promoting cross-bridge formation
D) triggering neurotransmitter release
Question
Glycolysis results in the breakdown of glucose into

A) creatine
B) fatty acids
C) lactic acid
D) pyruvic acid
Question
Jeff is holding his arm out to support a heavy book. After a while of maintaining the contraction, he is no longer able to exert any muscle force. This is a result of which phenomenon?

A) glycogenolysis
B) muscle fatigue
C) summation
D) aerobic respiration
Question
If you had a drug that physically blocked the ryanodine receptor itself, where in the cell would the drug be binding?

A) sarcolemma
B) sarcoplasmic reticulum
C) mitochondrion
D) troponin
Question
Curare is a plant based poison which is used by South American indigenous people as a toxin for hunting, the prey once shot by a dart coated with the toxin asphyxiate due to relaxation of skeletal muscles. Curare has also found use as a surgical anesthetic, again for its property of relaxing skeletal muscle. Which of the following is a possible mechanism for how curare could work?

A) curare inhibits acetylcholinesterase
B) curare activates ryanodine receptors
C) curare blocks sarcoplasmic reticulum Ca2+ ATPase pumps
D) curare blocks nicotinic acetylcholine receptors
Question
Muscle fatigue can be due to inadequate release of acetylcholine by motor neurons onto skeletal muscle fibers.
Question
Lactic acid is produced through which process(es)?

A) aerobic respiration
B) anaerobic respiration
C) creatine phosphate reaction
D) All of the choices are correct.
Question
Glucose enters skeletal muscle cells via simple diffusion.
Question
Which molecule can be used to quickly regenerate ATP by a direct phosphorylation reaction?

A) creatine phosphate
B) glycogen
C) lactic acid
D) pyruvate
Question
Hydrogen ions interfere with the ability of the sarcoplasmic reticulum to release calcium. Given this information, what effect do you think a decrease in pH would have on the force of muscle contraction?

A) decreased force of contraction
B) increased force of contraction
C) no effect on force of contraction
D) no contraction
Question
Skeletal muscle cells contain enough ATP to maximally contract for several minutes.
Question
Muscle contraction begins when calcium levels ______ and ends when they ______.

A) decrease; decrease
B) decrease; increase
C) increase; decrease
D) increase; increase
Question
After a skeletal muscle has contracted, which process is most important for lowering Ca2+ levels in the cytoplasm?

A) activity of the acetylcholine receptor
B) activity of the Ca2+-ATPase pump
C) closing of the Ca2+ release channels (ryanodine receptor)
D) closing of the dihydropyridine receptor
Question
Which of the following most accurately describes the effect of decreasing Ca2+ concentration on sarcomere activity?

A) troponin is deactivated and tropomyosin covers the actin binding site
B) tropomyosin is deactivated and troponin covers the actin binding site
C) myosin no longer hydrolyzes ATP and detaches from actin
D) myosin no longer binds ATP and recocks into an upright position
Question
Which process requires sufficient oxygen to occur?

A) aerobic respiration
B) anaerobic glycolysis
C) creatine phosphate reaction
D) aerobic respiration and anaerobic glycolysis
Question
Marathon runners often complete their events between 4 and 5 hours. Throughout the majority of this endurance event, which process is producing ATP?

A) anaerobic respiration
B) aerobic respiration
C) glycolysis fermentation
D) creatine phosphate reaction
Question
Which of the following best describes the activity of the ryanodine receptor?

A) nociceptor
B) mechanoreceptor
C) thermoreceptor
D) chemoreceptor
Question
When you begin to contract skeletal muscles, which is the first source used to replenish lost ATP?

A) glucose
B) glycogen
C) creatine-phosphate
D) fatty acids and ketone bodies
Question
Glucose can be made in skeletal muscle cells through the breakdown of ______.
Question
Which of the following would increase the tension produced by a skeletal muscle contraction?

A) increased recruitment of motor units
B) increased frequency of muscle action potentials
C) recruitment of more fast glycolytic muscle fibers
D) All of the choices are correct.
Question
When you bend your arm at the elbow, the movement is known as

A) agonism
B) extension
C) flexion
D) pronation
Question
Which of the following defines a motor unit?

A) a single motor neuron and all of the muscle fibers it innervates
B) a single muscle fiber and all of the motor neurons that innervate it
C) all of the motor neurons and muscle fibers necessary to produce a single movement
D) a group of motor neurons and muscle fibers that activate together
Question
The force a motor unit exerts depends on the rate at which the somatic motor neuron discharges action potentials because calcium is released from the sarcoplasmic reticulum faster than it is pumped back by the Ca2+-ATPase pump.
Question
Which type(s) of muscle fibers is/are most fatigue resistant?

A) fast glycolytic
B) slow oxidative
C) fast oxidative glycolytic
D) All of the choices are equally fatigue resistant.
Question
Which event does NOT occur during the relaxation period?

A) calcium is pumped by Ca2+-ATPase
B) myosin-binding sites are covered by tropomyosin
C) actin filaments extend back to their resting position
D) calcium levels are rising in the sarcoplasm
Question
Concentric and eccentric are types of ______ contractions.

A) isotonic
B) isometric
C) elastic
D) None of the choices is correct.
Question
Competitive weight lifters often try to exceed their own limits of performance by lifting heavier and heavier weights. Dwight is attempting to set his new personal record on the bench press and as he lowers the bar to his chest, he pushes it back up about halfway and begins to struggle. His spotter waits for two seconds while Dwight continues to work by himself, and suddenly the bar begins to move upwards again until it is fully extended, without the intervention of the spotter. Describe the types of muscle contractions that occurred while Dwight was struggling and while he followed through, respectively.

A) isometric, eccentric isotonic
B) isotonic, concentric isometric
C) eccentric, concentric isotonic
D) iosmetric, concentric isotonic
Question
You are holding a small textbook in your hand, and you begin to flex your elbow to raise the book. You stop with your elbow flexed at about 90 degrees, and the book held out in front of you. What is occurring in your biceps muscle at this time?

A) your biceps is in a state of unfused tetanus
B) your biceps is latched
C) Ca2+ is elevated in biceps muscle fibers
D) both your biceps is in a state of unfused tetanus AND Ca2+ is elevated in biceps muscle fibers
E) both your biceps is latched AND Ca2+ is elevated in biceps muscle fibers
Question
The muscle action potential travels down the T tubule system during the _____ period.
Question
A whole muscle is controlled by activation of a single motor unit.
Question
Imagine you want to produce a finely controlled movement (like picking up a wine glass by the stem). Would it be better to recruit a motor unit with a lower number of muscle fibers, or a motor unit with a higher number of muscle fibers?

A) higher
B) lower
C) either will do equally well
Question
A competitive marathon runner will likely have a higher than average number of which type of muscle fiber?

A) fast glycolytic
B) slow oxidative
C) fast oxidative glycolytic
D) equal amounts of all three
Question
Although an individual person's distribution of skeletal muscle fiber types is primarily genetically determined, there exists some evidence that fiber types can change in response to exercise to a limited degree (ie. a slow glycolytic fiber can change to a fast oxidative fiber). If such a change were to occur, which of the following proteins MUST change in some manner as the transition from one muscle type to another occurs?

A) actin
B) troponin
C) myosin
D) Ca2+-ATPase
Question
Which of the following is correct regarding unfused tetanus in a skeletal muscle fiber?

A) the muscle is being stimulated at a high rate, with some time to relax slightly between stimuli
B) the muscle is being stimulated at a high rate, with no time to relax slightly between stimuli
C) the muscle is producing its maximum tension
D) the muscle is fatigued
Question
No energy is expended during an isometric contraction because no actual movement is occurring.
Question
Jimothy is out cutting firewood with his dad and when they finish they need to carry it back to their campsite. Jimothy wants to impress his dad with how much would he can carry. What would be the most efficient way for him to carry the most wood while using the least amount of energy?

A) loading as many logs as close to his elbows as possible
B) loading as many logs in his hands as possible
C) loading some logs near his elbows and most on his hands
D) loading some logs near his hands and making multiple trips
Question
When the body produces movements, ______ function as fulcrums for levers and ______ act as the levers.
Question
Why do fast glycolytic skeletal muscle fibers have the greatest cross sectional area?

A) they are used for producing the greatest amount of force
B) they have the biggest thick filaments
C) they have the most sarcoplasmic reticulum
D) they are used for fine control of movement
Question
A competitive sprinter will likely have a higher than average number of which type of muscle fiber?

A) fast glycolytic
B) slow oxidative
C) fast oxidative glycolytic
D) equal amounts of all three
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Deck 11: Muscle
1
Given what you know about the musculature of the respiratory system, what is the most likely explanation for why you can change your breathing rate at any time?

A) the smooth muscles of the respiratory tract can be consciously controlled, unlike like other involuntary systems in the body
B) breathing rate is achieved through skeletal muscles, which are under partial voluntary control
C) in addition to smooth muscles that allow for conscious control, there are likely skeletal muscles involved that can be consciously controlled
D) there are skeletal muscles involved in breathing that display smooth muscle-like autorhythmicity
B
2
The muscle action potential quickly spreads into the muscle fiber as it travels along the _____, which is an extension of the _____.

A) myofibril; sarcoplasm
B) myofibril; sarcoplasmic reticulum
C) transverse tubules; sarcolemma
D) transverse tubules; sarcoplasm
C
3
The storage form of glucose that is present in muscles cells is known as ______.
glycogen
4
Calcium from the extracellular fluid is important for contraction of which type(s) of muscle?

A) cardiac only
B) cardiac and skeletal
C) cardiac and smooth
D) cardiac, skeletal and smooth
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5
Larry is stretching out his leg muscles before going for a run. Which property of muscle allows Larry to do this without hurting himself?

A) contractility
B) elasticity
C) electrical excitability
D) extensibility
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6
Which type(s) of muscle contraction is regulated by autonomic motor neurons?

A) cardiac only
B) cardiac and skeletal
C) cardiac and smooth
D) cardiac, skeletal and smooth
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7
After eating some questionable taco meat, your friend Joshua begins to throw up those risky tacos he ate only a few hours before. Which muscle function best explains why this might have occurred?

A) production of body movement
B) storage and movement of substances within the body
C) thermogenesis
D) stabilization of body position
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8
Which type(s) of muscle contraction can be regulated by acetylcholine?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
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9
Which muscle function explains why you get hot during strenuous exercise?

A) production of movement
B) involuntary stabilization
C) thermogenesis
D) moving substances within the body
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10
Which property of muscle allows the stretched muscles to go back to their original shape and size?

A) contractility
B) elasticity
C) electrical excitability
D) extensibility
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11
Which muscle property best explains the autorhythmicity of the heart?

A) electrical excitability
B) involuntary control
C) extensibility
D) contractility
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12
Which muscle property best explains how the heart generates your blood pressure?

A) elasticity
B) involuntary control
C) extensibility
D) contractility
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13
Which of the following muscle functions can explain why your head falls down when you begin to fall asleep during class?

A) production of body movement
B) storage and movement of substances within the body
C) thermogenesis
D) stabilization of body position
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14
Which of the following is the best explanation for why the statement "I can control my heart rate" is not entirely true?

A) It is not possible to consciously control other factors that affect heart rate, like breathing and physical activity, and so it is also not possible to consciously control heart muscle contractions.
B) It is possible to consciously control other factors that affect heart rate, like breathing and physical activity, but it is not possible to consciously control heart muscle contractions.
C) It is not possible to consciously control other factors that affect heart rate, like breathing and physical activity, but it is also possible to consciously control heart muscle contractions.
D) It is possible to consciously control other factors that affect heart rate, like breathing and physical activity, and it is possible to consciously control heart muscle contractions.
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15
Which type(s) of muscle can display(s) autorhythmicity?

A) cardiac only
B) cardiac and skeletal
C) cardiac and smooth
D) cardiac, skeletal and smooth
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16
Which type(s) of muscle contraction is regulated by somatic motor neurons?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
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17
Which type(s) of muscle have transverse tubules?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
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18
Sarcomeres are present in which type(s) of muscle?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
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19
Calcium from the sarcoplasmic reticulum is important for contraction of which type(s) of muscle?

A) cardiac and skeletal
B) cardiac, skeletal and smooth
C) skeletal and smooth
D) skeletal only
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20
Which type(s) of muscle contraction can be regulated by norepinephrine?

A) cardiac only
B) cardiac and skeletal
C) cardiac and smooth
D) cardiac, skeletal and smooth
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21
During a concentric muscle contraction, _______ moves along _______ toward the M line.

A) actin; myosin
B) myosin; actin
C) tropomyosin; actin
D) tropomyosin; troponin
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22
During an isotonic muscle contraction, what happens to the H zone?

A) it does not change
B) it gets longer
C) it gets shorter
D) it gets longer and shorter, successively
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23
Which of the following are the contractile proteins of muscle?

A) actin and myosin
B) dystrophin and actin
C) myosin and nebulin
D) tropomyosin and troponin
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24
Activation of nicotinic acetylcholine receptors on skeletal muscle cells most directly leads to a/an

A) action potential
B) end plate potential
C) autorhythmic potential
D) receptor potential
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25
During the depolarizing phase of a skeletal muscle action potential, ______ ions are moving _____ the cell and during the repolarizing phase _____ ions move _____ _____ the cell.
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26
Just like a neuronal action potential, a muscle action potential consists of a depolarizing phase caused by opening of voltage-gated sodium channels followed by a repolarizing phase due to opening of voltage-gated potassium channels and closing of voltage-gated sodium channels.
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27
Which muscle protein is responsible for attaching the M line to the Z line?

A) myosin
B) actin
C) titin
D) nebulin
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28
The A band corresponds to the full length of which component of the sarcomere?

A) thick filament
B) thin filament
C) titin filament
D) tropomyosin
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29
After a person or animal dies, the muscles of the body become very flaccid for a short period of time, before rigor mortis sets in. Which of the following is a possible explanation for why this brief state of flaccidity occurs?

A) Muscle cells become overexcited following death.
B) ATP is depleted and therefore there exists no energy for the contraction cycle.
C) Skeletal muscles require stimulation from the nervous system to contract, which ceases upon death.
D) Ca2+ leaks out of cells causing myosin to attach to actin.
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30
An end plate potential flows in one direction along a skeletal muscle fiber.
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31
Which molecule helps to anchor thin filaments to the ends of the sarcomere?

A) dystrophin
B) myomesin
C) nebulin
D) titin
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32
A somatic motor neuron releases _____ onto skeletal muscle to cause it to contract.
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33
What happens immediately after ATP attaches to myosin?

A) myosin head attaches to actin
B) myosin head detaches from actin
C) myosin head hydrolyzes ATP to ADP
D) myosin head pivots from 90o angle to 45o angle
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34
Certain pesticides inhibit acetylcholinesterase. What effects would this have on muscle fibers?

A) it would lead to increased muscle contractions
B) it would lead to increased muscle relaxation
C) it would lead to decreased muscle contractions
D) it would not change muscle fiber activity
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35
You are a scientist performing an experiment on some isolated skeletal muscle fibers. You observe that when you observe the muscle fibers under a microscope and apply a small amount of calcium, the fibers contract, but then after a short time they relax back to their original length. Which of the following is (are) possible explanation(s) for this observation?

A) The applied Ca2+ activates the muscle, but following the refractory period the Ca2+ loses its effect and the muscle relaxes.
B) The applied Ca2+ activates the muscle, but the muscle soon dephosphorylates its myosin and relaxes.
C) The applied Ca2+ at first activates the muscle, but then is pumped into the sarcoplasmic reticulum and is stored.
D) All of the choices are possible.
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36
Which molecule's activity is directly regulated by the presence and binding of calcium?

A) actin
B) myosin
C) tropomyosin
D) troponin
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37
What happens during the power stroke of the contraction cycle?

A) myosin head attaches to actin
B) myosin head detaches from actin
C) myosin head hydrolyzes ATP to ADP
D) myosin head pivots from 90o angle to 45o angle
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Unlock Deck
k this deck
38
Which of the following are regulatory proteins of muscle?

A) actin and myosin
B) dystrophin and titin
C) myomesin and nebulin
D) tropomyosin and troponin
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39
Which molecule blocks the myosin-binding sites by wrapping around the thin filament?

A) actin
B) myosin
C) tropomyosin
D) troponin
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40
Which molecule has an ATP-binding site?

A) actin
B) myosin
C) tropomyosin
D) troponin
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41
A buildup of which of the following can lead to skeletal muscle fatigue.

A) ADP
B) creatine phosphate
C) ATP
D) oxygen
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42
The skeletal muscle action potential is MOST DIRECTLY important for which process?

A) activating the DHP receptor
B) activating the ryanodine receptor
C) promoting cross-bridge formation
D) triggering neurotransmitter release
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43
Glycolysis results in the breakdown of glucose into

A) creatine
B) fatty acids
C) lactic acid
D) pyruvic acid
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44
Jeff is holding his arm out to support a heavy book. After a while of maintaining the contraction, he is no longer able to exert any muscle force. This is a result of which phenomenon?

A) glycogenolysis
B) muscle fatigue
C) summation
D) aerobic respiration
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45
If you had a drug that physically blocked the ryanodine receptor itself, where in the cell would the drug be binding?

A) sarcolemma
B) sarcoplasmic reticulum
C) mitochondrion
D) troponin
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46
Curare is a plant based poison which is used by South American indigenous people as a toxin for hunting, the prey once shot by a dart coated with the toxin asphyxiate due to relaxation of skeletal muscles. Curare has also found use as a surgical anesthetic, again for its property of relaxing skeletal muscle. Which of the following is a possible mechanism for how curare could work?

A) curare inhibits acetylcholinesterase
B) curare activates ryanodine receptors
C) curare blocks sarcoplasmic reticulum Ca2+ ATPase pumps
D) curare blocks nicotinic acetylcholine receptors
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47
Muscle fatigue can be due to inadequate release of acetylcholine by motor neurons onto skeletal muscle fibers.
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48
Lactic acid is produced through which process(es)?

A) aerobic respiration
B) anaerobic respiration
C) creatine phosphate reaction
D) All of the choices are correct.
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49
Glucose enters skeletal muscle cells via simple diffusion.
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50
Which molecule can be used to quickly regenerate ATP by a direct phosphorylation reaction?

A) creatine phosphate
B) glycogen
C) lactic acid
D) pyruvate
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51
Hydrogen ions interfere with the ability of the sarcoplasmic reticulum to release calcium. Given this information, what effect do you think a decrease in pH would have on the force of muscle contraction?

A) decreased force of contraction
B) increased force of contraction
C) no effect on force of contraction
D) no contraction
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52
Skeletal muscle cells contain enough ATP to maximally contract for several minutes.
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53
Muscle contraction begins when calcium levels ______ and ends when they ______.

A) decrease; decrease
B) decrease; increase
C) increase; decrease
D) increase; increase
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54
After a skeletal muscle has contracted, which process is most important for lowering Ca2+ levels in the cytoplasm?

A) activity of the acetylcholine receptor
B) activity of the Ca2+-ATPase pump
C) closing of the Ca2+ release channels (ryanodine receptor)
D) closing of the dihydropyridine receptor
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55
Which of the following most accurately describes the effect of decreasing Ca2+ concentration on sarcomere activity?

A) troponin is deactivated and tropomyosin covers the actin binding site
B) tropomyosin is deactivated and troponin covers the actin binding site
C) myosin no longer hydrolyzes ATP and detaches from actin
D) myosin no longer binds ATP and recocks into an upright position
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56
Which process requires sufficient oxygen to occur?

A) aerobic respiration
B) anaerobic glycolysis
C) creatine phosphate reaction
D) aerobic respiration and anaerobic glycolysis
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57
Marathon runners often complete their events between 4 and 5 hours. Throughout the majority of this endurance event, which process is producing ATP?

A) anaerobic respiration
B) aerobic respiration
C) glycolysis fermentation
D) creatine phosphate reaction
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58
Which of the following best describes the activity of the ryanodine receptor?

A) nociceptor
B) mechanoreceptor
C) thermoreceptor
D) chemoreceptor
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59
When you begin to contract skeletal muscles, which is the first source used to replenish lost ATP?

A) glucose
B) glycogen
C) creatine-phosphate
D) fatty acids and ketone bodies
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60
Glucose can be made in skeletal muscle cells through the breakdown of ______.
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61
Which of the following would increase the tension produced by a skeletal muscle contraction?

A) increased recruitment of motor units
B) increased frequency of muscle action potentials
C) recruitment of more fast glycolytic muscle fibers
D) All of the choices are correct.
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62
When you bend your arm at the elbow, the movement is known as

A) agonism
B) extension
C) flexion
D) pronation
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63
Which of the following defines a motor unit?

A) a single motor neuron and all of the muscle fibers it innervates
B) a single muscle fiber and all of the motor neurons that innervate it
C) all of the motor neurons and muscle fibers necessary to produce a single movement
D) a group of motor neurons and muscle fibers that activate together
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64
The force a motor unit exerts depends on the rate at which the somatic motor neuron discharges action potentials because calcium is released from the sarcoplasmic reticulum faster than it is pumped back by the Ca2+-ATPase pump.
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65
Which type(s) of muscle fibers is/are most fatigue resistant?

A) fast glycolytic
B) slow oxidative
C) fast oxidative glycolytic
D) All of the choices are equally fatigue resistant.
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66
Which event does NOT occur during the relaxation period?

A) calcium is pumped by Ca2+-ATPase
B) myosin-binding sites are covered by tropomyosin
C) actin filaments extend back to their resting position
D) calcium levels are rising in the sarcoplasm
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67
Concentric and eccentric are types of ______ contractions.

A) isotonic
B) isometric
C) elastic
D) None of the choices is correct.
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68
Competitive weight lifters often try to exceed their own limits of performance by lifting heavier and heavier weights. Dwight is attempting to set his new personal record on the bench press and as he lowers the bar to his chest, he pushes it back up about halfway and begins to struggle. His spotter waits for two seconds while Dwight continues to work by himself, and suddenly the bar begins to move upwards again until it is fully extended, without the intervention of the spotter. Describe the types of muscle contractions that occurred while Dwight was struggling and while he followed through, respectively.

A) isometric, eccentric isotonic
B) isotonic, concentric isometric
C) eccentric, concentric isotonic
D) iosmetric, concentric isotonic
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69
You are holding a small textbook in your hand, and you begin to flex your elbow to raise the book. You stop with your elbow flexed at about 90 degrees, and the book held out in front of you. What is occurring in your biceps muscle at this time?

A) your biceps is in a state of unfused tetanus
B) your biceps is latched
C) Ca2+ is elevated in biceps muscle fibers
D) both your biceps is in a state of unfused tetanus AND Ca2+ is elevated in biceps muscle fibers
E) both your biceps is latched AND Ca2+ is elevated in biceps muscle fibers
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70
The muscle action potential travels down the T tubule system during the _____ period.
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71
A whole muscle is controlled by activation of a single motor unit.
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72
Imagine you want to produce a finely controlled movement (like picking up a wine glass by the stem). Would it be better to recruit a motor unit with a lower number of muscle fibers, or a motor unit with a higher number of muscle fibers?

A) higher
B) lower
C) either will do equally well
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73
A competitive marathon runner will likely have a higher than average number of which type of muscle fiber?

A) fast glycolytic
B) slow oxidative
C) fast oxidative glycolytic
D) equal amounts of all three
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74
Although an individual person's distribution of skeletal muscle fiber types is primarily genetically determined, there exists some evidence that fiber types can change in response to exercise to a limited degree (ie. a slow glycolytic fiber can change to a fast oxidative fiber). If such a change were to occur, which of the following proteins MUST change in some manner as the transition from one muscle type to another occurs?

A) actin
B) troponin
C) myosin
D) Ca2+-ATPase
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75
Which of the following is correct regarding unfused tetanus in a skeletal muscle fiber?

A) the muscle is being stimulated at a high rate, with some time to relax slightly between stimuli
B) the muscle is being stimulated at a high rate, with no time to relax slightly between stimuli
C) the muscle is producing its maximum tension
D) the muscle is fatigued
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76
No energy is expended during an isometric contraction because no actual movement is occurring.
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77
Jimothy is out cutting firewood with his dad and when they finish they need to carry it back to their campsite. Jimothy wants to impress his dad with how much would he can carry. What would be the most efficient way for him to carry the most wood while using the least amount of energy?

A) loading as many logs as close to his elbows as possible
B) loading as many logs in his hands as possible
C) loading some logs near his elbows and most on his hands
D) loading some logs near his hands and making multiple trips
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78
When the body produces movements, ______ function as fulcrums for levers and ______ act as the levers.
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79
Why do fast glycolytic skeletal muscle fibers have the greatest cross sectional area?

A) they are used for producing the greatest amount of force
B) they have the biggest thick filaments
C) they have the most sarcoplasmic reticulum
D) they are used for fine control of movement
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80
A competitive sprinter will likely have a higher than average number of which type of muscle fiber?

A) fast glycolytic
B) slow oxidative
C) fast oxidative glycolytic
D) equal amounts of all three
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