Deck 6: Adaptive Immunity

Question 1

A macrophage was isolated and analyzed for major histocompatibility complex.Which of the following would be expected?

A) MHC I only
B) MHC II only
C) MHC I and II
D) Neither MHC I or MHC II

Answer 1

MHC I and II

Question 2

Which of the following statements indicates more teaching is needed regarding secondary lymph organs? ________is/are a secondary lymph organ.

A) The spleen
B) Peyer patches
C) Adenoids
D) The liver

Answer 2

The liver

Question 3

A 23-year-old pregnant female visits her primary care provider for her final prenatal checkup.The primary care provider determines that the fetus has developed an infection in utero.Which of the following would be increased in the fetus at birth?

A) IgG
B) IgA
C) IgM
D) IgD

Answer 3

IgM

Question 4

A 10-year-old male is stung by a bee while playing in the yard.He experiences a severe allergic reaction and has to go to the ER.The nurse providing care realizes this reaction is the result of:

A) Toxoids
B) IgA
C) IgE
D) IgM

Question 5

A 6-year-old female is diagnosed with a bacterial infection of the respiratory system.Which of the following will most likely try to fight the antigen?

A) Antibodies
B) Cytotoxic T cells
C) Self-antigens
D) Helper T cells

Question 6

The predominant antibody of a typical primary immune response is:

A) IgG
B) IgM
C) IgA
D) IgE

Question 7

After a patient is exposed to a specific antigen,B cells will differentiate into:

A) B cytotoxic cells
B) Clonal equivalents
C) Plasma cells
D) Bursal cells

Question 8

An immunologist has isolated a molecule from the human body to study.It is found to react with antibodies on B cells.Further testing reveals that the molecule is large and chemically diverse.What type of molecule is the immunologist studying?

A) Antigen
B) Immunogen
C) Epitope
D) Paratope

Question 9

Which of the following characteristics is shared by both the secretory and systemic immune systems?

A) Lymphocytic paths of migration
B) Neutralization following antigen-antibody binding
C) Timing of response
D) Location of response

Question 10

A 25-year-old female has sexual relations with her boyfriend.Later she is told that the boyfriend is infected with Neisseria gonorrhoeae.Testing reveals that she does not have the disease.How is it possible that she did not contract the disease?

A) Antibodies covered sites of attachment.
B) She was vaccinated against it.
C) Platelets provided protection.
D) IgE was released.

Question 11

A patient has done research on monoclonal antibodies on the Internet.Which statement indicates a correct understanding? Pure monoclonal antibodies are produced by:

A) T lymphocytes
B) Bone marrow
C) Laboratories
D) Fetuses

Question 12

Which portion of the antibody is responsible for the biologic functions of antibodies?

A) Heavy chain
B) Variable region
C) Fc portion
D) Epitope

Question 13

Which of the following is responsible for initiating clonal selection?

A) T cells
B) B cells
C) Antigens
D) Lymphocytes

Question 14

When the immunoglobulin crosses the placenta,what type of immunity does the fetus receive?

A) Active
B) Passive
C) Innate
D) Cell-mediated

Question 15

An experiment is designed to determine specific cell types involved in cell-mediated immune response.The experimenter is interested in finding cells that attack cells that have specific antigens.Which cells should be isolated?

A) Lymphokine-producing cells
B) Cytotoxic T cells
C) Helper T cells
D) Macrophages

Question 16

After teaching the students about B cells,which statement indicates teaching was successful? B cells are originally derived from cells of the:

A) Bone marrow
B) Lymph nodes
C) Gut-associated lymphoid tissue
D) Thymus

Question 17

Which statement indicates a correct understanding of antibodies? The most abundant class of antibody in the serum is:

A) IgG
B) IgM
C) IgA
D) IgE

Question 18

An experiment is carried out to characterize newly discovered immunoglobulins.Specificity of the amino acids within the immunoglobulin could be determined by studying the:

A) C region of the light chain
B) C region of the H chain
C) Complementary-determining region (CDR)
D) Framework regions

Question 19

An immunology nurse is caring for a patient.While planning care,which principle will the nurse remember? The primary role of IgA1 is to prevent infections in the:

A) Blood
B) Kidneys
C) Lungs
D) Mucous membranes

Question 20

A 20-year-old female is applying for nursing school and is required to be tested for immunity against several illnesses.Testing that looks at which of the following would be the best to determine immunity?

A) Culture and sensitivity
B) Agglutination
C) Precipitation
D) Titer

Question 21

Direct effects of antibodies include (select all that apply):

A) Neutralization
B) Agglutination
C) Precipitation
D) Phagocytosis
E) Division

Question 22

A patient has a disease state that results from the secretion of toxins by bacteria.Which medical diagnosis will the nurse see documented on the chart?

A) Malaria
B) Tetanus
C) Smallpox
D) Hepatitis

Question 23

A cell that is produced in the thymus and interacts with MHC class II molecules would have which of the following surface proteins?

A) CD4
B) CD8
C) Th1
D) Superantigen

Question 24

A 5-month-old child is admitted to the hospital with recurring respiratory infections.A possible cause of this condition is:

A) Hypergammaglobulinemia
B) Increased maternal IgG
C) Immune insufficiency
D) Decreased maternal antibody breakdown, resulting in hyposensitivity

Question 25

While planning care for an elderly patient,the nurse remembers that increased age is associated with (select all that apply):

A) Increased T cell function
B) Decreased immune function
C) Increased production of antibodies
D) Decreased numbers of circulating immune complexes
E) Decreased ability to fight infection

Question 26

Self-antigens do not meet the requirements for immunogenicity because they lack which of the following?

A) Foreignness
B) Size
C) Quantity
D) Virulence

Question 27

Which patient will develop active immunity? A patient who:

A) Has natural exposure to an antigen or receives an immunization
B) Receives preformed antibodies or T cells from a donor
C) Has T cells that become B cells
D) Receives immunoglobulin

Question 28

A 16-year-old is bitten by a rabid dog while jogging in the park.Upon admission to the emergency department,the nurse will administer which of the following to help prevent infection?

A) Cytotoxic T cells
B) Helper T cells
C) Macrophages
D) Immune globulin

Question 29

When a patient asks about secondary lymph organs,how should the nurse respond? Secondary lymph organs include (select all that apply):

A) Spleen
B) Peyer patches
C) Adenoids
D) Liver
E) Bone marrow
F) Appendix

Question 30

A 6-month-old infant is brought to the pediatrician for recurrent colds.The child is fed formula,and the other family members have not been ill.The primary care provider tells the mother that the child's immune system is not yet competent,but will be about 60% of an adult system around age _____ months.

A) 3
B) 6
C) 9
D) 12