Deck 3: Biological Molecules: the Carbon Compounds of Life
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Match between columns
Premises:
chemical formula at or close to a multiple of (CH2O)
chemical formula at or close to a multiple of (CH2O)
chemical formula at or close to a multiple of (CH2O)
chemical formula at or close to a multiple of (CH2O)
triglyceride
triglyceride
triglyceride
triglyceride
phosphodiester bond
phosphodiester bond
phosphodiester bond
phosphodiester bond
peptide bond
peptide bond
peptide bond
peptide bond
Responses:
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
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Deck 3: Biological Molecules: the Carbon Compounds of Life
1
Probably the most abundant carbohydrate on Earth, which unbranched chain of b-glucose subunits is the primary structural fiber in plant cell walls?
A) chitin
B) amylopectin
C) cellulose
D) glycogen
E) amylose
A) chitin
B) amylopectin
C) cellulose
D) glycogen
E) amylose
C
2

The disaccharide in the accompanying figure is ____.
A) lactose
B) fructose
C) maltose
D) cellulose
E) sucrose
A
3

The disaccharide in the accompanying figure is ____.
A) cellulose
B) galactose
C) maltose
D) sucrose
E) lactose
D
4
Suppose that an equal amount of each polysaccharide was placed in a landfill. Which polysaccharide should last the longest before it is decomposed?
A) chitin
B) amylopectin
C) cellulose
D) glycogen
E) amylose
A) chitin
B) amylopectin
C) cellulose
D) glycogen
E) amylose
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5
Which functional group acts as an organic base?
A) carbonyl
B) hydroxyl
C) phosphate
D) amino
E) carboxyl
A) carbonyl
B) hydroxyl
C) phosphate
D) amino
E) carboxyl
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6
Reactions that remove the equivalent of a water molecule when subunits are joined to make a larger molecule are called ____ reactions.
A) equilibrium
B) hydration
C) hydrolysis
D) redox
E) dehydration synthesis
A) equilibrium
B) hydration
C) hydrolysis
D) redox
E) dehydration synthesis
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7
Monosaccharides and disaccharides are types of ____.
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
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8
Which functional group forms the highly reactive part of aldehydes and ketones?
A) carbonyl
B) hydroxyl
C) phosphate
D) amino
E) carboxyl
A) carbonyl
B) hydroxyl
C) phosphate
D) amino
E) carboxyl
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9
When molecules are referred to as D- or L- (for example D-forms of sugars and L-forms of amino acids), the D- and L- designations refer to the specific ____.
A) functional group
B) structural isomer
C) covalent bond
D) secondary structure
E) stereoisomer
A) functional group
B) structural isomer
C) covalent bond
D) secondary structure
E) stereoisomer
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10
Which of these hydrocarbons has a double bond in its structure?
A) C3H8
B) C2H6
C) CH4
D) C2H4
E) C2H2
A) C3H8
B) C2H6
C) CH4
D) C2H4
E) C2H2
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11
Structural isomers differ from each other ____.
A) in the arrangement of their covalent bonds
B) in their molecular formulas
C) by being mirror images that cannot be superimposed on each other
D) by having double covalent bonds instead of single bonds
E) by having different atomic isotopes in their molecules
A) in the arrangement of their covalent bonds
B) in their molecular formulas
C) by being mirror images that cannot be superimposed on each other
D) by having double covalent bonds instead of single bonds
E) by having different atomic isotopes in their molecules
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12
Reactions that use the equivalent of a water molecule to break a molecule into smaller subunits are called ____ reactions.
A) equilibrium
B) hydration
C) hydrolysis
D) redox
E) dehydration synthesis
A) equilibrium
B) hydration
C) hydrolysis
D) redox
E) dehydration synthesis
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13

The molecule in the accompanying figure is mannose, an example of a ____ sugar.
A) triose
B) hexose
C) pentose
D) heptose
E) tetrose
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14
Amylose is a polymer made up of glucose monomers joined by ____.
A) b(1-4) linkages
B) b(1-6) linkages
C) a(1-4) linkages
D) a(1-6) linkages
E) both b(1-4) and a(1-6) linkages
A) b(1-4) linkages
B) b(1-6) linkages
C) a(1-4) linkages
D) a(1-6) linkages
E) both b(1-4) and a(1-6) linkages
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15
The linkage commonly found between subunits in a chain of monosaccharides is called a ____ bond.
A) phosphodiester
B) disulfide
C) glycosidic
D) hydrogen
E) peptide
A) phosphodiester
B) disulfide
C) glycosidic
D) hydrogen
E) peptide
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16

The accompanying figure illustrates the synthesis of ____.
A) sucrose
B) maltose
C) lactose
D) cellulose
E) fructose
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17
Isomers are two or more molecules with ____ chemical formula and ____ molecular structures.
A) a different; different
B) the same; different
C) a different; the same
D) the same; the same
E) a structural; theoretical
A) a different; different
B) the same; different
C) a different; the same
D) the same; the same
E) a structural; theoretical
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18

The molecule in the accompanying figure is glyceraldehyde, an example of a ____ sugar.
A) triose
B) hexose
C) pentose
D) heptose
E) tetrose
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19
Which functional group is polar and a key component of alcohols?
A) carbonyl
B) hydroxyl
C) phosphate
D) amino
E) carboxyl
A) carbonyl
B) hydroxyl
C) phosphate
D) amino
E) carboxyl
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20
Which polysaccharide is a chain of glucose units that are modified by having nitrogen-containing groups, is the main structural fiber in the external skeletons of arthropods, and also a structural material in the cell walls of fungi?
A) chitin
B) amylopectin
C) cellulose
D) glycogen
E) amylose
A) chitin
B) amylopectin
C) cellulose
D) glycogen
E) amylose
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21
Glycerol forms the backbone of ____.
A) triglycerides only
B) polysaccharides and nucleic acids
C) nucleic acids only
D) polypeptides only
E) triglycerides and phospholipids
A) triglycerides only
B) polysaccharides and nucleic acids
C) nucleic acids only
D) polypeptides only
E) triglycerides and phospholipids
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22
The molecule in the accompanying figure is ____, and has ____.
A) unsaturated; a carbon-carbon double bond
B) saturated; a carbon-carbon double bond
C) unsaturated; no carbon-carbon double bonds
D) saturated; no carbon-carbon double bonds
E) saturated; a carbon-carbon triple bond
A) unsaturated; a carbon-carbon double bond
B) saturated; a carbon-carbon double bond
C) unsaturated; no carbon-carbon double bonds
D) saturated; no carbon-carbon double bonds
E) saturated; a carbon-carbon triple bond
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23
In many animals, this polysaccharide is found in large quantities in liver and muscle cells. It is highly branched, with many a(1-4) and a(1-6) linkages.
A) chitin
B) amylopectin
C) cellulose
D) glycogen
E) amylose
A) chitin
B) amylopectin
C) cellulose
D) glycogen
E) amylose
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24

The molecule shown above is a(n) ____.
A) triglyceride
B) amino acid
C) steroid
D) polysaccharide
E) phospholipid
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25
If three molecules of a fatty acid having the formula C16H22O2are each joined to a molecule of glycerol (C3H8O3) by a dehydration synthesis reaction, what will be the formula of the resulting neutral fat molecule?
A) C48H66O6.
B) C48H72O8.
C) C51H68O6.
D) C51H72O8.
E) C51H74O9.
A) C48H66O6.
B) C48H72O8.
C) C51H68O6.
D) C51H72O8.
E) C51H74O9.
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26
Sterol regulatory element binding proteins (SREBPs) are involved in regulating the synthesis of ____.
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
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27
We would expect to find fatty acids with ____ carbons in living organisms.
A) eight
B) 13
C) 16
D) 19
E) 26
A) eight
B) 13
C) 16
D) 19
E) 26
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28
Which molecule is the main structural component of biological membranes?
A) starch
B) triglyceride
C) protein
D) phospholipid
E) steroid
A) starch
B) triglyceride
C) protein
D) phospholipid
E) steroid
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29
HDL cholesterol is considered "good" cholesterol. What role does HDL play in preventing coronary heart disease?
A) HDL cholesterol inhibits LDL cholesterol synthesis
B) HDL cholesterol prevents transport of LDL cholesterol in blood
C) HDL cholesterol activates LDL cholesterol breakdown
D) HDL cholesterol prevents free radical formation in plaques
E) HDL cholesterol removes excess cholesterol from plaques
A) HDL cholesterol inhibits LDL cholesterol synthesis
B) HDL cholesterol prevents transport of LDL cholesterol in blood
C) HDL cholesterol activates LDL cholesterol breakdown
D) HDL cholesterol prevents free radical formation in plaques
E) HDL cholesterol removes excess cholesterol from plaques
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30
A fatty acid has a(n)____ group at the end of a hydrocarbon chain.
A) carbonyl group
B) hydroxyl group
C) phosphate group
D) amino group
E) carboxyl group
A) carbonyl group
B) hydroxyl group
C) phosphate group
D) amino group
E) carboxyl group
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31

The molecule shown above is a(n) ____.
A) triglyceride
B) amino acid
C) steroid
D) polysaccharide
E) phospholipid
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32
The sex hormones of many animals are lipid molecules known as ____.
A) fatty acids
B) phospholipids
C) carotenoids
D) steroids
E) lipoproteins
A) fatty acids
B) phospholipids
C) carotenoids
D) steroids
E) lipoproteins
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33
Amino acids are linked together by ____ bonds.
A) phosphodiester
B) disulfide
C) glycosidic
D) hydrogen
E) peptide
A) phosphodiester
B) disulfide
C) glycosidic
D) hydrogen
E) peptide
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34
Testosterone has important regulatory functions in humans and many other animals. Molecules with regulatory functions like testosterone are called ____.
A) phytosterols
B) enzymes
C) lipoproteins
D) hormones
E) receptors
A) phytosterols
B) enzymes
C) lipoproteins
D) hormones
E) receptors
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35

The molecule in the accompanying figure is ____, and has ____.
A) unsaturated; a carbon-carbon double bond
B) saturated; a carbon-carbon double bond
C) unsaturated; no carbon-carbon double bonds
D) saturated; no carbon-carbon double bonds
E) saturated; a carbon-carbon triple bond.
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36

The molecule in the accompanying figure is a(n) ____.
A) triglyceride
B) amino acid
C) steroid
D) polysaccharide
E) phospholipid
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37
Waxy coatings, such as those found on skin, hair, and feathers of some animals and the cuticle of some plants, are commonly used by living organisms for protection against water loss and for lubrication. Such waxes are considered to be a type of ____.
A) triglyceride
B) steroid
C) neutral lipid
D) phospholipid
E) fatty acid
A) triglyceride
B) steroid
C) neutral lipid
D) phospholipid
E) fatty acid
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38
Proteins are polymers of ____.
A) amino acids
B) monosaccharides
C) steroids
D) nucleotides
E) phospholipids
A) amino acids
B) monosaccharides
C) steroids
D) nucleotides
E) phospholipids
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39
Which class of molecule is the most diverse in terms of structure and roles played in cells?
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
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40
Why are trans fats more harmful for consumption than saturated fats?
A) Trans fats increase LDL cholesterol levels more than saturated fats.
B) Trans fats decrease HDL cholesterol levels more than saturated fats.
C) Saturated fats prevent LDL transport more than trans fats.
D) Trans fats are often consumed with other food additives that increase fat absorption in the gut.
E) Saturated fats are more natural, and better digested in the gut.
A) Trans fats increase LDL cholesterol levels more than saturated fats.
B) Trans fats decrease HDL cholesterol levels more than saturated fats.
C) Saturated fats prevent LDL transport more than trans fats.
D) Trans fats are often consumed with other food additives that increase fat absorption in the gut.
E) Saturated fats are more natural, and better digested in the gut.
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41
In his experiments, Anfinsen treated a protein with a chemical that broke disulfide bonds and then removed the chemical to see how this would affect the function of the molecule. What did he conclude from these experiments?
A) The information for determining the three-dimensional shape of ribonuclease lies in its amino acid sequence.
B) The disulfide bonds are essential for quaternary, but not tertiary, protein structure.
C) Protein conformation is maintained when disulfide bonds are disrupted.
D) Altering the three-dimensional shape of the protein is irreversible.
E) Disulfide bonds are unnecessary for proper protein function.
A) The information for determining the three-dimensional shape of ribonuclease lies in its amino acid sequence.
B) The disulfide bonds are essential for quaternary, but not tertiary, protein structure.
C) Protein conformation is maintained when disulfide bonds are disrupted.
D) Altering the three-dimensional shape of the protein is irreversible.
E) Disulfide bonds are unnecessary for proper protein function.
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42
Which molecules are the most important for a cell to protect from damage if the cell is to stay alive and reproduce?
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
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43
In proteins, structural segments called ____ provide flexibility that allow parts of the protein to bend, fold, or move.
A) random coils
B) peptide bonds
C) b sheets
D) a helices
E) b polysaccharides
A) random coils
B) peptide bonds
C) b sheets
D) a helices
E) b polysaccharides
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44

The molecule in the accompanying figure is the pyrimidine ____, which is typically found in DNA but not RNA.
A) thymine
B) adenine
C) uracil
D) guanine
E) cytosine
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45
The unique sequence of monomer subunits in a protein is the ____ structure of the protein.
A) primary
B) secondary
C) tertiary
D) quaternary
E) linear
A) primary
B) secondary
C) tertiary
D) quaternary
E) linear
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46
The sugar in DNA is comprised of ____ carbons.
A) three
B) four
C) five
D) six
E) seven
A) three
B) four
C) five
D) six
E) seven
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47
After a long period of gradual evolution of protein domains, a period of explosive change (the "big bang") in protein domain complexity occurred at roughly the same time as the three taxonomic domains were undergoing rapid diversification. In which taxonomic domain was this diversification most extensive?
A) Eukarya
B) Protista
C) Archaea
D) Animalia
E) Bacteria
A) Eukarya
B) Protista
C) Archaea
D) Animalia
E) Bacteria
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48

The two amino acids in the accompanying figure both have side chains ( R groups) that are ____.
A) acidic and polar
B) uncharged and nonpolar
C) basic and polar
D) acidic and nonpolar
E) uncharged and polar
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49
A hydrogen bond between the amino acid side chains ( R groups) of two different polypeptide chains in a multichain protein would be considered part of the ____ structure of the protein.
A) primary
B) secondary
C) tertiary
D) quaternary
E) linear
A) primary
B) secondary
C) tertiary
D) quaternary
E) linear
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50

The two amino acids in the accompanying figure both have side chains ( R groups) that are ____.
A) acidic and polar
B) uncharged and nonpolar
C) basic and polar
D) acidic and nonpolar
E) uncharged and polar
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51
Excessive heat or extremes of pH often cause denaturation of proteins, which means that the proteins ____.
A) have fallen apart into individual monomer subunits
B) are no longer biological molecules
C) have broken into many separate domains
D) are no longer in a functional three-dimensional conformation
E) are highly reactive
A) have fallen apart into individual monomer subunits
B) are no longer biological molecules
C) have broken into many separate domains
D) are no longer in a functional three-dimensional conformation
E) are highly reactive
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52
In an elegant set of experiments, which protein did Anfinsen study in order to understand how the three-dimensional structure of proteins is determined?
A) ovalbumin
B) chaperonin
C) ribonuclease
D) insulin
E) hemoglobin
A) ovalbumin
B) chaperonin
C) ribonuclease
D) insulin
E) hemoglobin
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53

The molecule shown above is the purine ____.
A) thymine
B) adenine
C) uracil
D) guanine
E) cytosine
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54

The two amino acids in the accompanying figure both have side chains ( R groups) that are ____.
A) acidic and polar
B) uncharged and nonpolar
C) basic and polar
D) acidic and nonpolar
E) uncharged and polar
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55

The molecule in the accompanying figure is the pyrimidine ____, which is typically found in both DNA and RNA.
A) thymine
B) adenine
C) uracil
D) guanine
E) cytosine
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56
Chaperonins assist with ____.
A) proteins synthesis
B) assembly of DNA strands
C) polysaccharide synthesis
D) protein folding
E) forming the DNA double helix
A) proteins synthesis
B) assembly of DNA strands
C) polysaccharide synthesis
D) protein folding
E) forming the DNA double helix
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57
Which amino acid can be involved in special covalent "disulfide bridges" that, when present, help to stabilize the tertiary and quaternary structure of proteins?
A) proline
B) alanine
C) leucine
D) cysteine
E) methionine
A) proline
B) alanine
C) leucine
D) cysteine
E) methionine
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58
Hereditary information in all eukaryotes, prokaryotes, and viruses is stored in ____.
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
A) proteins
B) lipids
C) nucleic acids
D) carbohydrates
E) amino acids
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59

The image in the accompanying figure is an example of a(n) ____.
A) random coil
B) double helix
C) b sheet
D) a helix
E) b polysaccharide
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60

The two amino acids depicted above both have side chains ( R groups) that are ____.
A) acidic and polar
B) uncharged and nonpolar
C) basic and polar
D) acidic and nonpolar
E) uncharged and polar
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61
Nucleotides are joined together to make a nucleic acid strand by ____ bonds.
A) phosphodiester
B) disulfide
C) glycosidic
D) hydrogen
E) peptide
A) phosphodiester
B) disulfide
C) glycosidic
D) hydrogen
E) peptide
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62
Consider the DNA sequence 5'-GATTACA-3'. If the strand with this sequence forms a double helix with another DNA strand, the sequence on the other strand should be ____.
A) 5'-TCGGCAC-3'
B) 3'-GATTACA-5'
C) 5'- ACATTAG-3'
D) 3'-GTGCCGA-5'
E) 3'-CTAATGT-5'
A) 5'-TCGGCAC-3'
B) 3'-GATTACA-5'
C) 5'- ACATTAG-3'
D) 3'-GTGCCGA-5'
E) 3'-CTAATGT-5'
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63
Two structural differences between a uridine monophosphate and thymidine monophosphate are ____ and ____.
A) the number of hydrogen bonds formed between it and its matching base; the presence of a hydroxyl group on the ribose
B) the presence of a methyl group on the nitrogen base; the presence of a hydroxyl group on the ribose
C) the number of hydrogen bonds formed between it and its matching base; the presence of a methyl group on the nitrogen base
D) the number of hydrogen bonds formed between it and its matching base; the location of the ribose attachment to the nitrogenous base
E) the presence of a methyl group of the nitrogen base; the location of the ribose attachment to the nitrogenous base
A) the number of hydrogen bonds formed between it and its matching base; the presence of a hydroxyl group on the ribose
B) the presence of a methyl group on the nitrogen base; the presence of a hydroxyl group on the ribose
C) the number of hydrogen bonds formed between it and its matching base; the presence of a methyl group on the nitrogen base
D) the number of hydrogen bonds formed between it and its matching base; the location of the ribose attachment to the nitrogenous base
E) the presence of a methyl group of the nitrogen base; the location of the ribose attachment to the nitrogenous base
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64
Which two nucleotides also serve as transporters of chemical energy?
A) ATP and GTP
B) ATP and CTP
C) ATP and TTP
D) CTP and TTP
E) CTP and UTP
A) ATP and GTP
B) ATP and CTP
C) ATP and TTP
D) CTP and TTP
E) CTP and UTP
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65
In addition to serving as building blocks of DNA, what other function do nucleotides perform in a cell?
A) regulate cellular activity
B) regulate gene expression
C) chaperone protein folding
D) activate vesicular transport
E) trigger muscle contractions
A) regulate cellular activity
B) regulate gene expression
C) chaperone protein folding
D) activate vesicular transport
E) trigger muscle contractions
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66
Match between columns
Premises:
chemical formula at or close to a multiple of (CH2O)
chemical formula at or close to a multiple of (CH2O)
chemical formula at or close to a multiple of (CH2O)
chemical formula at or close to a multiple of (CH2O)
triglyceride
triglyceride
triglyceride
triglyceride
phosphodiester bond
phosphodiester bond
phosphodiester bond
phosphodiester bond
peptide bond
peptide bond
peptide bond
peptide bond
Responses:
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
nucleic acid
carbohydrate
protein
lipid
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67
Describe the general structure of amino acids.
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68
Are saturated or unsaturated fats generally solids at room temperature? Explain why there is a difference in the fluidity of these two related molecules.
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69
A large molecule whose subunits consist of a sugar and a nitrogenous base is called a ____.
A) nucleoside
B) nucleotide
C) nucleic acid
D) nucleosome
E) nuclear unit
A) nucleoside
B) nucleotide
C) nucleic acid
D) nucleosome
E) nuclear unit
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70
The two strands of a DNA double helix are held to each other by ____ bonds between nitrogenous bases.
A) phosphodiester
B) disulfide
C) glycosidic
D) hydrogen
E) peptide
A) phosphodiester
B) disulfide
C) glycosidic
D) hydrogen
E) peptide
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71
Glucose and fructose, which have the same chemical formula, are considered stereoisomers .
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72
When DNA is heated, the hydrogen bonds break and allow the two strands of DNA to separate from one another. Which sequence of DNA would be most resistant to heating, and therefore stay double stranded longer?
A) AATTGGCC
B) ATGCATTC
C) AGGAGCTC
D) TGGCTTAG
E) TACCAATT
A) AATTGGCC
B) ATGCATTC
C) AGGAGCTC
D) TGGCTTAG
E) TACCAATT
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73
Approximately how many base pairs comprise one turn of the double helix in DNA?
A) 2.5
B) 5
C) 10
D) 20
E) 50
A) 2.5
B) 5
C) 10
D) 20
E) 50
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74
How many hydrogen bonds are formed between adenine and thymine?
A) one
B) two
C) three
D) four
E) six
A) one
B) two
C) three
D) four
E) six
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75
Using what you know about how carbohydrate monomers are linked to form polymers, explain why most animals can digest starch more easily than cellulose?
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76
The tertiary structure of proteins is the three-dimensional shape comprised of two or more polypeptides.
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77
The most abundant organic molecules in the world are nucleic acids .
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78
Chitin is a reinforcing fiber in the external skeleton of arthropods.
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79
Unsaturated fats are considered healthier than saturated fats in the human diet.
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80
RNA is significantly less stable than DNA. Based on the structural differences between these molecules, what is a plausible hypothesis as to why this is?
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