Deck 5: Membranes and Transport

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Question
The selective permeability of a cell membrane is due to ____.

A) the hydrophobic core formed by the phospholipid tails
B) the hydrophilic surface facing the cell's exterior
C) glycolipids on the surface of the membrane
D) the position of cholesterol in the membrane bilayer
E) the hydrophilic core formed by the phospholipid tails
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Question
Organisms must constantly bring in certain molecules and ions while keeping others out. This function is accomplished by ____.

A) the nucleus
B) lysosomes
C) vesicles
D) the plasma membrane
E) the Golgi complex
Question
The "mosaic" part of the fluid mosaic model refers to the membrane ____.

A) proteins
B) phospholipids
C) cholesterol
D) functions
E) layers
Question
Which proteins in the plasma membrane identify a cell as part of the same individual or as foreign?

A) transport proteins
B) recognition proteins
C) receptor proteins
D) cell adhesion proteins
E) nuclear proteins
Question
Which protein group links cells together by recognizing and binding receptors or chemical groups on other cells or the extracellular matrix?

A) transport proteins
B) recognition proteins
C) receptor proteins
D) cell adhesion proteins
E) nuclear proteins
Question
According to the fluid mosaic model of cell membranes, the fluid part of the model refers to ____.

A) the constant movement of the hydrophilic tails in the interior of the membrane
B) a thin layer of water found sandwiched between the two layers of phospholipids
C) the phospholipid molecules that vibrate, spin, and exchange places within the same layer of the bilayer
D) the free movement of cholesterol molecules within the membrane
E) the frequent flip-flop of phospholipids from one side of the membrane to the other
Question
The major structural components of a cell membrane are ____.

A) phospholipids and cellulose
B) phospholipids, protein, and sterols
C) protein and sterols
D) glycolipids and proteins
E) phospholipids and glycolipids
Question
As part of an experiment, researchers grew several different types of cells in the presence of radioactive iodine. After some time had passed, the cells were washed, and the levels of iodine inside the cell were determined. What is the most plausible explanation for why some cells had higher levels of radioactivity after treatment than others?

A) Cells that had high radioactivity levels after treatment contain iodine transporters.
B) Cells that had high radioactivity levels after treatment lack iodine transporters.
C) Cells that had high radioactivity levels after treatment had a mutation in genes encoding iodine transporter proteins.
D) Cells that had high radioactivity levels after treatment lack clathrin.
E) Cells that had high radioactivity levels after treatment lack lysosomes.
Question
Which proteins would be considered peripheral membrane proteins?

A) aquaporins
B) cell adhesion proteins
C) carrier proteins
D) microtubules
E) receptors
Question
Which proteins form channels in the membrane that allow selected polar molecules and ions to pass through and across the membrane?

A) transport proteins
B) recognition proteins
C) receptor proteins
D) cell adhesion proteins
E) nuclear proteins
Question
Which type of lipid is most important to the structure of biological membranes?

A) fat
B) wax
C) phospholipid
D) neutral fat
E) triglyceride
Question
Which molecules demonstrate dual solubility characteristics?

A) sterols only
B) proteins only
C) phospholipids only
D) sterols and phospholipids
E) sterols, phospholipids, and proteins
Question
Cystic fibrosis primarily affects which organ?

A) brain
B) heart
C) muscle
D) lungs
E) bones
Question
In an aqueous environment, the phospholipids of a membrane ____.

A) are arranged in a single layer
B) are arranged in a bilayer with the polar heads of each layer located at the membrane surface
C) are arranged in a bilayer with the fatty acid tails located at the membrane surface
D) are arranged in a bilayer but the phospholipids have no specific orientation
E) dissociate into their lipid and protein components
Question
Membrane sterols, such as cholesterol, function in animal cell membranes to ____.

A) increase the rate of diffusion
B) store cellular energy
C) facilitate ion transport
D) maintain membrane fluidity
E) receive chemical signals
Question
Our current view of membrane structure is based on the fluid mosaic model, proposed by ____ in 1972.

A) Frye and Edidin
B) Watson and Crick
C) Singer and Goldstein
D) S. Singer and G. Nicolson
E) Brown and Goldstein
Question
Which proteins recognize and bind molecules from other cells that act as chemical signals?

A) transport proteins
B) recognition proteins
C) receptor proteins
D) cell adhesion proteins
E) nuclear proteins
Question
Glycolipids and glycoproteins form a surface coat on the outside of the cell surface called a ____, which protects the cell against chemical and mechanical damage.

A) cell wall
B) outer matrix
C) extracellular matrix
D) glycocalyx
E) lipid raft
Question
When referring to membrane glycolipids and glycoproteins, the term "glyco-" indicates ____.

A) carbohydrate groups are attached to the molecules
B) the molecules are bound to the glycocalyx
C) the molecules are found on both the interior and exterior of the membrane
D) the molecules are attached to the membrane by ionic bonds
E) the molecules are rarely found on the membrane exterior
Question
Which class of proteins is embedded in the phospholipid bilayer?

A) cytoskeletal proteins
B) integral membrane proteins
C) transcription factor proteins
D) peripheral membrane proteins
E) protein hormones
Question
Which adaptation to the plasma membrane allows mammals to hibernate in subzero temperatures without their plasma membranes freezing?

A) increase in cholesterol content only
B) increase in protein content only
C) increase in the number of double covalent bonds in phospholipids
D) increase in both cholesterol and protein content
E) increase in both cholesterol and double covalent bonds in phospholipids
Question
Movement of a substance from an area of low concentration to an area of high concentration using energy obtained from ATP is called ____.

A) passive transport
B) diffusion
C) facilitated transport
D) osmosis
E) active transport
Question
What is the energy source for facilitated diffusion?

A) ATP hydrolysis
B) concentration gradients
C) glucose metabolism
D) GTP hydrolysis
E) lipid phosphorylation
Question
A scientist fused a mouse cell and a human cell, then treated the cell with specific antibodies covalently linked to colored fluorescent dyes (antibodies to mouse proteins were labeled green; antibodies to human proteins were labeled red). Forty minutes later, what will the researcher observe?

A) The fused cell will still be half red and half green.
B) The red and green fluorescent labels will be uniformly distributed throughout the entire membrane.
C) The red and green labels will be distributed in intermingled patches.
D) The red and green labels will flash intermittently.
E) The red and green labels will be distributed in a swirling pattern.
Question
The ____ component of the cell membrane functions as a selective barrier, while the ____ component has specific functions such as transport, recognizing other cells, and binding to other cells.

A) carbohydrate; nucleic acid
B) protein; lipid
C) lipid; protein
D) lipid; carbohydrate
E) carbohydrate; protein
Question
Carrier proteins are utilized for ____.

A) active transport only
B) passive transport only
C) both active and passive transport
D) osmosis
E) transport of all types of molecules
Question
The polar end of a phospholipid contains a phosphate group bound to ____, while the nonpolar end contains ____.

A) alcohols or amino acids; two fatty-acid tails
B) glycoproteins; one fatty-acid tail
C) two fatty-acid tails; sterols
D) variable proteins; cholesterol
E) water; choline
Question
Which function of cellular membranes is critical to the molecular organization of cells?

A) the controlled transport of ions and molecules across the membrane
B) cell-cell binding
C) recognition of other cells as being "foreign" or "self"
D) reception of chemical signals from other cells
E) participation in metabolic reactions
Question
What happens when the concentrations of a solute that can freely diffuse across a membrane are equal inside and outside the cell?

A) The osmotic pressure is equilibrated on both sides of the membrane.
B) Solute molecules no longer diffuse across the membrane.
C) Solute molecules continue to diffuse across the membrane.
D) Transporter proteins are inhibited to prevent movement across the membrane.
E) Channel proteins are gated to prevent movement across the membrane.
Question
When a drop of food coloring is placed in a container of clear water, the colored dye molecules ____.

A) diffuse to a different location by osmosis
B) diffuse to a different location by active transport
C) concentrate at the top of the container
D) diffuse equally throughout the container
E) stay at the bottom of the container
Question
Facilitated diffusion is specific, which indicates that ____.

A) a specific protein will transport certain polar or charged molecules but not others
B) only one specific integral membrane protein per membrane is involved in this process
C) the energy molecule ATP is specifically required for transport
D) only specific hydrophobic molecules can be transported
E) transport of molecules occurs only in specific cells
Question
Which organelle's membrane contains the enzymes that convert light energy to chemical energy in eukaryotes?

A) plasma
B) chloroplast
C) Golgi complex
D) lysosome
E) endoplasmic reticulum
Question
Polar and charged molecules typically cross the cell membrane by way of ____.

A) simple diffusion
B) osmosis
C) filtration
D) active transport
E) facilitated diffusion
Question
A channel that opens in response to changes in ionic charge across a membrane is called a(n) ____ channel.

A) voltage-gated
B) ligand-gated
C) charge-gated
D) electric-gated
E) positive-gated
Question
Carrier proteins are often used by the cell to transport ____.

A) H2O
B) proteins
C) amino acids
D) steroid hormones
E) CO2
Question
In what way do the various membranes of a cell differ?

A) Phospholipids are found only in certain membranes.
B) Certain proteins are unique to each membrane.
C) Only certain membranes are constructed from molecules with dual solubility.
D) Only certain membranes of a cell are selectively permeable.
E) Some membranes have hydrophobic surfaces exposed to the cytoplasm, while others have hydrophilic surfaces facing the cytoplasm.
Question
Transport of a molecule across a cell membrane by facilitated diffusion ____.

A) does not exhibit specificity for a particular type of molecule
B) requires the input of energy
C) depends on a concentration gradient
D) goes against the concentration gradient
E) allows nonpolar uncharged molecules to diffuse across a membrane
Question
Aquaporins are ____.

A) pores made of water molecules
B) required for water to enter a cell
C) found only in bacterial cells
D) specific channels for water transport
E) useful for cell signaling
Question
The selective permeability of a membrane refers to the ____.

A) movement of a molecule from an area of high concentration to an area of low concentration
B) ability of a substance to pass through any membrane
C) ability of only certain molecules to pass across a membrane
D) need for carrier proteins to transport some molecules across a membrane
E) ability of molecules to be transported across a membrane
Question
Which molecules most easily diffuse across a cell membrane?

A) ionic
B) large, polar
C) large, hydrophilic
D) small, hydrophobic
E) large, hydrophobic
Question
For osmosis to occur, ____.

A) a selectively permeable membrane must be present
B) a concentration gradient cannot exist
C) cellular energy must be expended
D) pure water must be on one side of the membrane
E) only solutes can pass through the membrane
Question
The voltage across a membrane is called the ____.

A) electrochemical gradient
B) turgor pressure
C) membrane potential
D) chemical gradient
E) electron potential
Question
Mutations in different types of aquaporin proteins lead to a variety of clinical manifestations, such as diabetes insipidus, epileptic seizures, and cataracts. What best explains the differences in the conditions caused by these mutations?

A) Different types of aquaporin proteins allow different rates of water diffusion.
B) Different aquaporin proteins are localized to different membranes in the cell.
C) Different types of aquaporin proteins are produced in different cell types.
D) Different types of aquaporin proteins alter the amount of water retention within a cell.
E) Different aquaporin proteins have different functions within the cells.
Question
The movement of water across a membrane from an area of high to low water concentration is an example of ____.

A) active transport only
B) endocytosis only
C) osmosis only
D) both osmosis and active transport
E) both diffusion and osmosis
Question
Which ion is actively transported to regulate pollen growth and fertilization?

A) hydrogen
B) potassium
C) sodium
D) calcium
E) magnesium
Question
A red blood cell placed in a beaker of solution immediately begins to swell and ultimately bursts. This occurs because the cytoplasm of the cell was ____ to the solution in the beaker, which was ____.

A) hypertonic; hypotonic
B) hypotonic; hypertonic
C) hypotonic; isotonic
D) hypertonic; isotonic
E) isotonic; hypotonic
Question
The movement of water across a membrane from an area of lower solute concentration to a region of higher solute concentration is called ____.

A) osmosis only
B) active transport only
C) endocytosis only
D) both diffusion and osmosis
E) both osmosis and active transport
Question
A(n) ____ environment is ideal for plant cells, while a(n) ____ environment is best for animal cells.

A) isotonic; hypotonic
B) hypotonic; isotonic
C) hypotonic; hypertonic
D) hypertonic; isotonic
E) isotonic; isotonic
Question
The force that pushes plant cell membranes tightly against the cell wall and helps support softer tissues against the force of gravity is known as ____ pressure.

A) turgor
B) osmotic
C) diffusion
D) concentration
E) plasmolysis
Question
In plants, extreme wilting of leaves and stems can cause the cells to retract from the cell wall, a condition known as ____.

A) hemolysis
B) an increase in turgor pressure
C) plasmolysis
D) a lack of solutes in the cell
E) a higher than normal concentration of water in the cell
Question
An isotonic solution has a solute concentration ____ the solute concentration inside the cell.

A) equal to
B) greater than
C) less than
D) that depends on
E) that alters
Question
When a plant cell is placed in a hypotonic solution, the cell wall prevents ____.

A) plasmolysis
B) diffusion
C) active transport
D) the cell from bursting
E) the cell from shrinking
Question
The Na+/K+pump creates a ____ charge inside the cell and a ____ charge outside the cell.

A) negative; negative
B) positive; negative
C) positive; positive
D) negative; positive
E) neutral; positive
Question
The net movement of molecules or ions from a low concentration to a higher concentration is called ____.

A) active transport
B) facilitated diffusion
C) exocytosis
D) osmosis
E) diffusion
Question
A(n) ____ gradient is created as ions diffuse across membranes.

A) chemical
B) electrochemical
C) negative
D) electrical
E) active
Question
Two solutions of differing glucose concentration are placed in a container separated by a selectively permeable membrane that restricts large molecules like glucose, but allows the free diffusion of water. What will be the glucose concentration in the container after dynamic equilibrium has been reached?

A) The water molecules will be evenly distributed in the container, with more glucose molecules on one side than the other.
B) The volumes of the solution will be different, with a higher volume on the side that originally contained the higher concentration of glucose.
C) The volumes of the solution will be different, with a lower volume on the side that originally contained the higher concentration of glucose.
D) The glucose concentration of the two solutions will be identical on both sides of the membrane, but the volumes will remain unchanged.
E) The volume and concentrations will be unchanged on both sides of the membrane.
Question
Humans with mutations in the AQP1 (aquaporin-1) gene do not produce the AQP1 protein. The absence of AQP1 causes an inability to ____ in these individuals.

A) produce concentrated urine
B) recognize thirst
C) make large volumes of dilute urine
D) control sweating
E) salivate
Question
Which process moves materials against a concentration gradient?

A) active transport
B) dialysis
C) facilitated diffusion
D) simple diffusion
E) osmosis
Question
The pressure that must be applied to a solution to prevent water movement across a membrane is known as ____ pressure.

A) turgor
B) osmotic
C) diffusion
D) concentration
E) plasmolysis
Question
Distilled water is ____ to body cells.

A) isotonic
B) hypertonic
C) hypotonic
D) protonic
E) aquatonic
Question
Match between columns
Hypertonic
C
Hypertonic
A
Hypertonic
B
Hypotonic
C
Hypotonic
A
Hypotonic
B
Isotonic
C
Isotonic
A
Isotonic
B
Question
Cells undergo exocytosis ____.

A) to pump protons down a concentration gradient
B) when replicating
C) to secrete protein and wastes from the cell
D) to ingest nutrients
E) as a means of cellular protection
Question
Match between columns
Cholesterol
C
Cholesterol
B
Cholesterol
A
Cholesterol
E
Cholesterol
D
Carbohydrate groups
C
Carbohydrate groups
B
Carbohydrate groups
A
Carbohydrate groups
E
Carbohydrate groups
D
Microfilament
C
Microfilament
B
Microfilament
A
Microfilament
E
Microfilament
D
Peripheral membrane proteins
C
Peripheral membrane proteins
B
Peripheral membrane proteins
A
Peripheral membrane proteins
E
Peripheral membrane proteins
D
Integral membrane proteins
C
Integral membrane proteins
B
Integral membrane proteins
A
Integral membrane proteins
E
Integral membrane proteins
D
Question
In secondary active transport, when both the driving ion and the transport ion are in high concentration outside of the cell, in which direction will the two ions move?

A) As the driving ion moves in, the transport ion moves in.
B) As the driving ion moves in, the transport ion moves out.
C) As the driving ion moves out, the transport ion moves in.
D) As the driving ion moves out, the transport ion moves out.
E) As long as both ions are moving together, they can go either in or out.
Question
Pinocytosis and phagocytosis are accomplished in the cell by the ____.

A) nucleus
B) lysosome
C) endoplasmic reticulum
D) plasma membrane
E) mitochondria
Question
Match between columns
osmosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
osmosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
osmosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
osmosis
Large particles are enveloped by the cell membrane and internalized.
osmosis
A process in which liquid droplets are ingested by living cells.
osmosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
osmosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
facilitated diffusion
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
facilitated diffusion
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
facilitated diffusion
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
facilitated diffusion
Large particles are enveloped by the cell membrane and internalized.
facilitated diffusion
A process in which liquid droplets are ingested by living cells.
facilitated diffusion
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
facilitated diffusion
Movement of a molecule from an area of high concentration to an area of lower concentration.
diffusion
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
diffusion
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
diffusion
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
diffusion
Large particles are enveloped by the cell membrane and internalized.
diffusion
A process in which liquid droplets are ingested by living cells.
diffusion
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
diffusion
Movement of a molecule from an area of high concentration to an area of lower concentration.
receptor-mediated endocytosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
receptor-mediated endocytosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
receptor-mediated endocytosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
receptor-mediated endocytosis
Large particles are enveloped by the cell membrane and internalized.
receptor-mediated endocytosis
A process in which liquid droplets are ingested by living cells.
receptor-mediated endocytosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
receptor-mediated endocytosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
pinocytosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
pinocytosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
pinocytosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
pinocytosis
Large particles are enveloped by the cell membrane and internalized.
pinocytosis
A process in which liquid droplets are ingested by living cells.
pinocytosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
pinocytosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
exocytosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
exocytosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
exocytosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
exocytosis
Large particles are enveloped by the cell membrane and internalized.
exocytosis
A process in which liquid droplets are ingested by living cells.
exocytosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
exocytosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
phagocytosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
phagocytosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
phagocytosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
phagocytosis
Large particles are enveloped by the cell membrane and internalized.
phagocytosis
A process in which liquid droplets are ingested by living cells.
phagocytosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
phagocytosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
Question
Bulk endocytosis is also called pinocytosis.
Question
Cholesterol is essential for keeping cell membranes from thickening .
Question
Where do exocytic secretory vesicles originate?

A) endoplasmic reticulum
B) plasma membrane
C) the Golgi complex
D) lysosomes
E) microbodies
Question
Explain why the transport of molecules across the cell membrane is considered to be both specific and directional.
Question
A transport system in which the transport of an ion in one direction provides the energy for active transport in the opposite direction is known as ____.

A) antiport
B) active diffusion
C) symport
D) facilitated diffusion
E) osmosis
Question
A hypertonic environment would be ideal for a healthy plant.
Question
In patients with familial hypercholesterolemia, which cellular process is inhibited?

A) bulk endocytosis
B) receptor mediated endocytosis
C) exocytosis
D) primary active transport
E) secondary active transport
Question
In primary active transport, the carrier protein that transports a substance also hydrolyzes ATP to power the transport directly.
Question
In order to visualize LDL entry into the cell, researchers tagged the LDL with which heavy metal?

A) iron
B) mercury
C) lead
D) manganese
E) zinc
Question
In secondary active transport, when the driving ion concentration is high and the transport ion concentration is low outside of the cell, in which direction will the two ions move?

A) As the driving ion moves in, the transport ion moves in.
B) As the driving ion moves in, the transport ion moves out.
C) As the driving ion moves out, the transport ion moves in.
D) As the driving ion moves out, the transport ion moves out.
E) As long as both ions are moving together, they can go either in or out.
Question
People with type A blood have red blood cells that express one type of recognition protein, while those with type B blood express a different recognition protein. People with AB blood express both recognition proteins. Why can a person with AB blood receive blood from a person with type A, but a person with type A blood cannot receive blood from a person with type AB?
Question
In receptor-mediated endocytosis, the receptors collect into a depression called a coated pit for endocytosis after the target molecules bind to them.
Question
Which molecules coat the inside of the cytosolic membrane to help form endocytic vesicles?

A) clathrins
B) cholesterols
C) antibodies
D) aquaporins
E) microtubules
Question
The Na+/K+pump transports ____.

A) two sodium ions in and two potassium ions out
B) two sodium ions in and three potassium ions out
C) two sodium ions out and three potassium ions in
D) three sodium ions in and two potassium ions out
E) three sodium ions out and two potassium ions in
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Deck 5: Membranes and Transport
1
The selective permeability of a cell membrane is due to ____.

A) the hydrophobic core formed by the phospholipid tails
B) the hydrophilic surface facing the cell's exterior
C) glycolipids on the surface of the membrane
D) the position of cholesterol in the membrane bilayer
E) the hydrophilic core formed by the phospholipid tails
A
2
Organisms must constantly bring in certain molecules and ions while keeping others out. This function is accomplished by ____.

A) the nucleus
B) lysosomes
C) vesicles
D) the plasma membrane
E) the Golgi complex
D
3
The "mosaic" part of the fluid mosaic model refers to the membrane ____.

A) proteins
B) phospholipids
C) cholesterol
D) functions
E) layers
A
4
Which proteins in the plasma membrane identify a cell as part of the same individual or as foreign?

A) transport proteins
B) recognition proteins
C) receptor proteins
D) cell adhesion proteins
E) nuclear proteins
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5
Which protein group links cells together by recognizing and binding receptors or chemical groups on other cells or the extracellular matrix?

A) transport proteins
B) recognition proteins
C) receptor proteins
D) cell adhesion proteins
E) nuclear proteins
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6
According to the fluid mosaic model of cell membranes, the fluid part of the model refers to ____.

A) the constant movement of the hydrophilic tails in the interior of the membrane
B) a thin layer of water found sandwiched between the two layers of phospholipids
C) the phospholipid molecules that vibrate, spin, and exchange places within the same layer of the bilayer
D) the free movement of cholesterol molecules within the membrane
E) the frequent flip-flop of phospholipids from one side of the membrane to the other
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7
The major structural components of a cell membrane are ____.

A) phospholipids and cellulose
B) phospholipids, protein, and sterols
C) protein and sterols
D) glycolipids and proteins
E) phospholipids and glycolipids
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8
As part of an experiment, researchers grew several different types of cells in the presence of radioactive iodine. After some time had passed, the cells were washed, and the levels of iodine inside the cell were determined. What is the most plausible explanation for why some cells had higher levels of radioactivity after treatment than others?

A) Cells that had high radioactivity levels after treatment contain iodine transporters.
B) Cells that had high radioactivity levels after treatment lack iodine transporters.
C) Cells that had high radioactivity levels after treatment had a mutation in genes encoding iodine transporter proteins.
D) Cells that had high radioactivity levels after treatment lack clathrin.
E) Cells that had high radioactivity levels after treatment lack lysosomes.
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9
Which proteins would be considered peripheral membrane proteins?

A) aquaporins
B) cell adhesion proteins
C) carrier proteins
D) microtubules
E) receptors
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10
Which proteins form channels in the membrane that allow selected polar molecules and ions to pass through and across the membrane?

A) transport proteins
B) recognition proteins
C) receptor proteins
D) cell adhesion proteins
E) nuclear proteins
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11
Which type of lipid is most important to the structure of biological membranes?

A) fat
B) wax
C) phospholipid
D) neutral fat
E) triglyceride
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12
Which molecules demonstrate dual solubility characteristics?

A) sterols only
B) proteins only
C) phospholipids only
D) sterols and phospholipids
E) sterols, phospholipids, and proteins
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13
Cystic fibrosis primarily affects which organ?

A) brain
B) heart
C) muscle
D) lungs
E) bones
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14
In an aqueous environment, the phospholipids of a membrane ____.

A) are arranged in a single layer
B) are arranged in a bilayer with the polar heads of each layer located at the membrane surface
C) are arranged in a bilayer with the fatty acid tails located at the membrane surface
D) are arranged in a bilayer but the phospholipids have no specific orientation
E) dissociate into their lipid and protein components
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15
Membrane sterols, such as cholesterol, function in animal cell membranes to ____.

A) increase the rate of diffusion
B) store cellular energy
C) facilitate ion transport
D) maintain membrane fluidity
E) receive chemical signals
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16
Our current view of membrane structure is based on the fluid mosaic model, proposed by ____ in 1972.

A) Frye and Edidin
B) Watson and Crick
C) Singer and Goldstein
D) S. Singer and G. Nicolson
E) Brown and Goldstein
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17
Which proteins recognize and bind molecules from other cells that act as chemical signals?

A) transport proteins
B) recognition proteins
C) receptor proteins
D) cell adhesion proteins
E) nuclear proteins
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18
Glycolipids and glycoproteins form a surface coat on the outside of the cell surface called a ____, which protects the cell against chemical and mechanical damage.

A) cell wall
B) outer matrix
C) extracellular matrix
D) glycocalyx
E) lipid raft
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19
When referring to membrane glycolipids and glycoproteins, the term "glyco-" indicates ____.

A) carbohydrate groups are attached to the molecules
B) the molecules are bound to the glycocalyx
C) the molecules are found on both the interior and exterior of the membrane
D) the molecules are attached to the membrane by ionic bonds
E) the molecules are rarely found on the membrane exterior
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20
Which class of proteins is embedded in the phospholipid bilayer?

A) cytoskeletal proteins
B) integral membrane proteins
C) transcription factor proteins
D) peripheral membrane proteins
E) protein hormones
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21
Which adaptation to the plasma membrane allows mammals to hibernate in subzero temperatures without their plasma membranes freezing?

A) increase in cholesterol content only
B) increase in protein content only
C) increase in the number of double covalent bonds in phospholipids
D) increase in both cholesterol and protein content
E) increase in both cholesterol and double covalent bonds in phospholipids
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22
Movement of a substance from an area of low concentration to an area of high concentration using energy obtained from ATP is called ____.

A) passive transport
B) diffusion
C) facilitated transport
D) osmosis
E) active transport
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23
What is the energy source for facilitated diffusion?

A) ATP hydrolysis
B) concentration gradients
C) glucose metabolism
D) GTP hydrolysis
E) lipid phosphorylation
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24
A scientist fused a mouse cell and a human cell, then treated the cell with specific antibodies covalently linked to colored fluorescent dyes (antibodies to mouse proteins were labeled green; antibodies to human proteins were labeled red). Forty minutes later, what will the researcher observe?

A) The fused cell will still be half red and half green.
B) The red and green fluorescent labels will be uniformly distributed throughout the entire membrane.
C) The red and green labels will be distributed in intermingled patches.
D) The red and green labels will flash intermittently.
E) The red and green labels will be distributed in a swirling pattern.
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25
The ____ component of the cell membrane functions as a selective barrier, while the ____ component has specific functions such as transport, recognizing other cells, and binding to other cells.

A) carbohydrate; nucleic acid
B) protein; lipid
C) lipid; protein
D) lipid; carbohydrate
E) carbohydrate; protein
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26
Carrier proteins are utilized for ____.

A) active transport only
B) passive transport only
C) both active and passive transport
D) osmosis
E) transport of all types of molecules
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27
The polar end of a phospholipid contains a phosphate group bound to ____, while the nonpolar end contains ____.

A) alcohols or amino acids; two fatty-acid tails
B) glycoproteins; one fatty-acid tail
C) two fatty-acid tails; sterols
D) variable proteins; cholesterol
E) water; choline
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28
Which function of cellular membranes is critical to the molecular organization of cells?

A) the controlled transport of ions and molecules across the membrane
B) cell-cell binding
C) recognition of other cells as being "foreign" or "self"
D) reception of chemical signals from other cells
E) participation in metabolic reactions
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29
What happens when the concentrations of a solute that can freely diffuse across a membrane are equal inside and outside the cell?

A) The osmotic pressure is equilibrated on both sides of the membrane.
B) Solute molecules no longer diffuse across the membrane.
C) Solute molecules continue to diffuse across the membrane.
D) Transporter proteins are inhibited to prevent movement across the membrane.
E) Channel proteins are gated to prevent movement across the membrane.
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30
When a drop of food coloring is placed in a container of clear water, the colored dye molecules ____.

A) diffuse to a different location by osmosis
B) diffuse to a different location by active transport
C) concentrate at the top of the container
D) diffuse equally throughout the container
E) stay at the bottom of the container
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31
Facilitated diffusion is specific, which indicates that ____.

A) a specific protein will transport certain polar or charged molecules but not others
B) only one specific integral membrane protein per membrane is involved in this process
C) the energy molecule ATP is specifically required for transport
D) only specific hydrophobic molecules can be transported
E) transport of molecules occurs only in specific cells
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32
Which organelle's membrane contains the enzymes that convert light energy to chemical energy in eukaryotes?

A) plasma
B) chloroplast
C) Golgi complex
D) lysosome
E) endoplasmic reticulum
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33
Polar and charged molecules typically cross the cell membrane by way of ____.

A) simple diffusion
B) osmosis
C) filtration
D) active transport
E) facilitated diffusion
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34
A channel that opens in response to changes in ionic charge across a membrane is called a(n) ____ channel.

A) voltage-gated
B) ligand-gated
C) charge-gated
D) electric-gated
E) positive-gated
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35
Carrier proteins are often used by the cell to transport ____.

A) H2O
B) proteins
C) amino acids
D) steroid hormones
E) CO2
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36
In what way do the various membranes of a cell differ?

A) Phospholipids are found only in certain membranes.
B) Certain proteins are unique to each membrane.
C) Only certain membranes are constructed from molecules with dual solubility.
D) Only certain membranes of a cell are selectively permeable.
E) Some membranes have hydrophobic surfaces exposed to the cytoplasm, while others have hydrophilic surfaces facing the cytoplasm.
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37
Transport of a molecule across a cell membrane by facilitated diffusion ____.

A) does not exhibit specificity for a particular type of molecule
B) requires the input of energy
C) depends on a concentration gradient
D) goes against the concentration gradient
E) allows nonpolar uncharged molecules to diffuse across a membrane
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38
Aquaporins are ____.

A) pores made of water molecules
B) required for water to enter a cell
C) found only in bacterial cells
D) specific channels for water transport
E) useful for cell signaling
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39
The selective permeability of a membrane refers to the ____.

A) movement of a molecule from an area of high concentration to an area of low concentration
B) ability of a substance to pass through any membrane
C) ability of only certain molecules to pass across a membrane
D) need for carrier proteins to transport some molecules across a membrane
E) ability of molecules to be transported across a membrane
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40
Which molecules most easily diffuse across a cell membrane?

A) ionic
B) large, polar
C) large, hydrophilic
D) small, hydrophobic
E) large, hydrophobic
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41
For osmosis to occur, ____.

A) a selectively permeable membrane must be present
B) a concentration gradient cannot exist
C) cellular energy must be expended
D) pure water must be on one side of the membrane
E) only solutes can pass through the membrane
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42
The voltage across a membrane is called the ____.

A) electrochemical gradient
B) turgor pressure
C) membrane potential
D) chemical gradient
E) electron potential
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43
Mutations in different types of aquaporin proteins lead to a variety of clinical manifestations, such as diabetes insipidus, epileptic seizures, and cataracts. What best explains the differences in the conditions caused by these mutations?

A) Different types of aquaporin proteins allow different rates of water diffusion.
B) Different aquaporin proteins are localized to different membranes in the cell.
C) Different types of aquaporin proteins are produced in different cell types.
D) Different types of aquaporin proteins alter the amount of water retention within a cell.
E) Different aquaporin proteins have different functions within the cells.
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44
The movement of water across a membrane from an area of high to low water concentration is an example of ____.

A) active transport only
B) endocytosis only
C) osmosis only
D) both osmosis and active transport
E) both diffusion and osmosis
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45
Which ion is actively transported to regulate pollen growth and fertilization?

A) hydrogen
B) potassium
C) sodium
D) calcium
E) magnesium
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46
A red blood cell placed in a beaker of solution immediately begins to swell and ultimately bursts. This occurs because the cytoplasm of the cell was ____ to the solution in the beaker, which was ____.

A) hypertonic; hypotonic
B) hypotonic; hypertonic
C) hypotonic; isotonic
D) hypertonic; isotonic
E) isotonic; hypotonic
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47
The movement of water across a membrane from an area of lower solute concentration to a region of higher solute concentration is called ____.

A) osmosis only
B) active transport only
C) endocytosis only
D) both diffusion and osmosis
E) both osmosis and active transport
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48
A(n) ____ environment is ideal for plant cells, while a(n) ____ environment is best for animal cells.

A) isotonic; hypotonic
B) hypotonic; isotonic
C) hypotonic; hypertonic
D) hypertonic; isotonic
E) isotonic; isotonic
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49
The force that pushes plant cell membranes tightly against the cell wall and helps support softer tissues against the force of gravity is known as ____ pressure.

A) turgor
B) osmotic
C) diffusion
D) concentration
E) plasmolysis
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50
In plants, extreme wilting of leaves and stems can cause the cells to retract from the cell wall, a condition known as ____.

A) hemolysis
B) an increase in turgor pressure
C) plasmolysis
D) a lack of solutes in the cell
E) a higher than normal concentration of water in the cell
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51
An isotonic solution has a solute concentration ____ the solute concentration inside the cell.

A) equal to
B) greater than
C) less than
D) that depends on
E) that alters
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52
When a plant cell is placed in a hypotonic solution, the cell wall prevents ____.

A) plasmolysis
B) diffusion
C) active transport
D) the cell from bursting
E) the cell from shrinking
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53
The Na+/K+pump creates a ____ charge inside the cell and a ____ charge outside the cell.

A) negative; negative
B) positive; negative
C) positive; positive
D) negative; positive
E) neutral; positive
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54
The net movement of molecules or ions from a low concentration to a higher concentration is called ____.

A) active transport
B) facilitated diffusion
C) exocytosis
D) osmosis
E) diffusion
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55
A(n) ____ gradient is created as ions diffuse across membranes.

A) chemical
B) electrochemical
C) negative
D) electrical
E) active
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56
Two solutions of differing glucose concentration are placed in a container separated by a selectively permeable membrane that restricts large molecules like glucose, but allows the free diffusion of water. What will be the glucose concentration in the container after dynamic equilibrium has been reached?

A) The water molecules will be evenly distributed in the container, with more glucose molecules on one side than the other.
B) The volumes of the solution will be different, with a higher volume on the side that originally contained the higher concentration of glucose.
C) The volumes of the solution will be different, with a lower volume on the side that originally contained the higher concentration of glucose.
D) The glucose concentration of the two solutions will be identical on both sides of the membrane, but the volumes will remain unchanged.
E) The volume and concentrations will be unchanged on both sides of the membrane.
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57
Humans with mutations in the AQP1 (aquaporin-1) gene do not produce the AQP1 protein. The absence of AQP1 causes an inability to ____ in these individuals.

A) produce concentrated urine
B) recognize thirst
C) make large volumes of dilute urine
D) control sweating
E) salivate
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58
Which process moves materials against a concentration gradient?

A) active transport
B) dialysis
C) facilitated diffusion
D) simple diffusion
E) osmosis
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59
The pressure that must be applied to a solution to prevent water movement across a membrane is known as ____ pressure.

A) turgor
B) osmotic
C) diffusion
D) concentration
E) plasmolysis
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60
Distilled water is ____ to body cells.

A) isotonic
B) hypertonic
C) hypotonic
D) protonic
E) aquatonic
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61
Match between columns
Hypertonic
C
Hypertonic
A
Hypertonic
B
Hypotonic
C
Hypotonic
A
Hypotonic
B
Isotonic
C
Isotonic
A
Isotonic
B
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62
Cells undergo exocytosis ____.

A) to pump protons down a concentration gradient
B) when replicating
C) to secrete protein and wastes from the cell
D) to ingest nutrients
E) as a means of cellular protection
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63
Match between columns
Cholesterol
C
Cholesterol
B
Cholesterol
A
Cholesterol
E
Cholesterol
D
Carbohydrate groups
C
Carbohydrate groups
B
Carbohydrate groups
A
Carbohydrate groups
E
Carbohydrate groups
D
Microfilament
C
Microfilament
B
Microfilament
A
Microfilament
E
Microfilament
D
Peripheral membrane proteins
C
Peripheral membrane proteins
B
Peripheral membrane proteins
A
Peripheral membrane proteins
E
Peripheral membrane proteins
D
Integral membrane proteins
C
Integral membrane proteins
B
Integral membrane proteins
A
Integral membrane proteins
E
Integral membrane proteins
D
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64
In secondary active transport, when both the driving ion and the transport ion are in high concentration outside of the cell, in which direction will the two ions move?

A) As the driving ion moves in, the transport ion moves in.
B) As the driving ion moves in, the transport ion moves out.
C) As the driving ion moves out, the transport ion moves in.
D) As the driving ion moves out, the transport ion moves out.
E) As long as both ions are moving together, they can go either in or out.
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65
Pinocytosis and phagocytosis are accomplished in the cell by the ____.

A) nucleus
B) lysosome
C) endoplasmic reticulum
D) plasma membrane
E) mitochondria
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66
Match between columns
osmosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
osmosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
osmosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
osmosis
Large particles are enveloped by the cell membrane and internalized.
osmosis
A process in which liquid droplets are ingested by living cells.
osmosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
osmosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
facilitated diffusion
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
facilitated diffusion
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
facilitated diffusion
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
facilitated diffusion
Large particles are enveloped by the cell membrane and internalized.
facilitated diffusion
A process in which liquid droplets are ingested by living cells.
facilitated diffusion
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
facilitated diffusion
Movement of a molecule from an area of high concentration to an area of lower concentration.
diffusion
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
diffusion
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
diffusion
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
diffusion
Large particles are enveloped by the cell membrane and internalized.
diffusion
A process in which liquid droplets are ingested by living cells.
diffusion
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
diffusion
Movement of a molecule from an area of high concentration to an area of lower concentration.
receptor-mediated endocytosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
receptor-mediated endocytosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
receptor-mediated endocytosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
receptor-mediated endocytosis
Large particles are enveloped by the cell membrane and internalized.
receptor-mediated endocytosis
A process in which liquid droplets are ingested by living cells.
receptor-mediated endocytosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
receptor-mediated endocytosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
pinocytosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
pinocytosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
pinocytosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
pinocytosis
Large particles are enveloped by the cell membrane and internalized.
pinocytosis
A process in which liquid droplets are ingested by living cells.
pinocytosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
pinocytosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
exocytosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
exocytosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
exocytosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
exocytosis
Large particles are enveloped by the cell membrane and internalized.
exocytosis
A process in which liquid droplets are ingested by living cells.
exocytosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
exocytosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
phagocytosis
Secretory vesicles that have moved through the cytoplasm along microtubules contact the plasma membrane and release their contents
phagocytosis
Movement of water from a hypotonic solution into a hypertonic solution across a selectively permeable membrane.
phagocytosis
Diffusion of molecules across the plasma membrane with the assistance of transport proteins.
phagocytosis
Large particles are enveloped by the cell membrane and internalized.
phagocytosis
A process in which liquid droplets are ingested by living cells.
phagocytosis
Cells internalize molecules into a cell by the inward budding of vesicles possessing receptors specific to the molecule being transported.
phagocytosis
Movement of a molecule from an area of high concentration to an area of lower concentration.
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67
Bulk endocytosis is also called pinocytosis.
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68
Cholesterol is essential for keeping cell membranes from thickening .
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69
Where do exocytic secretory vesicles originate?

A) endoplasmic reticulum
B) plasma membrane
C) the Golgi complex
D) lysosomes
E) microbodies
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70
Explain why the transport of molecules across the cell membrane is considered to be both specific and directional.
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71
A transport system in which the transport of an ion in one direction provides the energy for active transport in the opposite direction is known as ____.

A) antiport
B) active diffusion
C) symport
D) facilitated diffusion
E) osmosis
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72
A hypertonic environment would be ideal for a healthy plant.
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73
In patients with familial hypercholesterolemia, which cellular process is inhibited?

A) bulk endocytosis
B) receptor mediated endocytosis
C) exocytosis
D) primary active transport
E) secondary active transport
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74
In primary active transport, the carrier protein that transports a substance also hydrolyzes ATP to power the transport directly.
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75
In order to visualize LDL entry into the cell, researchers tagged the LDL with which heavy metal?

A) iron
B) mercury
C) lead
D) manganese
E) zinc
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76
In secondary active transport, when the driving ion concentration is high and the transport ion concentration is low outside of the cell, in which direction will the two ions move?

A) As the driving ion moves in, the transport ion moves in.
B) As the driving ion moves in, the transport ion moves out.
C) As the driving ion moves out, the transport ion moves in.
D) As the driving ion moves out, the transport ion moves out.
E) As long as both ions are moving together, they can go either in or out.
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77
People with type A blood have red blood cells that express one type of recognition protein, while those with type B blood express a different recognition protein. People with AB blood express both recognition proteins. Why can a person with AB blood receive blood from a person with type A, but a person with type A blood cannot receive blood from a person with type AB?
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78
In receptor-mediated endocytosis, the receptors collect into a depression called a coated pit for endocytosis after the target molecules bind to them.
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79
Which molecules coat the inside of the cytosolic membrane to help form endocytic vesicles?

A) clathrins
B) cholesterols
C) antibodies
D) aquaporins
E) microtubules
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80
The Na+/K+pump transports ____.

A) two sodium ions in and two potassium ions out
B) two sodium ions in and three potassium ions out
C) two sodium ions out and three potassium ions in
D) three sodium ions in and two potassium ions out
E) three sodium ions out and two potassium ions in
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