Deck 7: Prion Infections

Question 1

Prions are alive in the biological sense.

Answer 1

False

Question 2

Who described proteins as "fundamental substances"?

Answer 2

Gerhard Mulder

Question 3

Who isolated and purified a pathogenic protein, the prion?

Answer 3

Stanley Prusiner

Question 4

What does BSE stands for?

Question 5

Prions are roughly how large?

Question 6

In humans, the incubation period of prion-associated disease may be as long as three decades.

Question 7

BSE remained unknown in cattle until what decade?

A) 1960s
B) 1970s
C) 1980s
D) 1990s
E) 2000s

Question 8

This sheep is suffering from what condition?

Question 9

Kuru is a unique form of human TSE found in what country?

A) Indonesia
B) Papua-New Guinea
C) Malaysia
D) Singapore
E) Australia

Question 10

Kuru is transmitted how?

Question 11

Where was BSE was first identified?

A) England
B) Scotland
C) Ireland
D) Wales
E) Canada

Question 12

What is the popular name for BSE?

Question 13

Human Creutzfeldt-Jakob disease produces what characteristic lesions in the brain?

A) Darkened areas
B) Whitish areas
C) Darkened, sponge-like areas
D) Whitish, sponge-like areas
E) All of these are correct.

Question 14

Human Creutzfeldt-Jakob Disease produces typical flu-like symptoms.

Question 15

About what percent of healthcare-acquired CJD is due to dural transplants?

A) Roughly 60%
B) Roughly 70%
C) Roughly 80%
D) Roughly 90%
E) Nearly 100%

Question 16

CJD occurs at about what rate?

A) Roughly 1 case per million population
B) Roughly 1.5 cases per million population
C) Roughly 2 cases per million population
D) Roughly 2.5 cases per million population
E) > 2.5 cases per million population

Question 17

There is universal susceptibility to vCJD.