Deck 6: Attention and Developmental Disorders: Attention-Deficithyperactivity Disorder and Autism Spectrum Disorder

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Question
ADHD is characterized by ________ and ________.

A) excessive talking; an inability to follow instructions
B) an inability to attend to tasks; an excessive display of motor activity and impulsivity
C) inattention to cognitive tasks; excessive talking
D) excessive fidgeting; disruptive classroom behaviors
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Question
Which of the following statements is TRUE regarding ADHD?

A) A diagnosis of ADHD usually occurs in late childhood.
B) In many cases, ADHD symptoms dissipate by early adulthood.
C) Approximately 8 percent of children under the age of ten are diagnosed with ADHD at any given time.
D) Childhood ADHD frequently occurs with other behavioral disorders.
Question
All of the following behaviors would be consistent with an ADHD diagnosis EXCEPT

A) trouble organizing activities.
B) careless mistakes and inattention to detail.
C) excessive speech.
D) excessive concentration on a single task.
Question
The underlying pathology of ADHD involves

A) cortical hypoarousal.
B) reticular activating system abnormalities.
C) depressed dopamine activity in the frontal cortices.
D) All of the above are correct
Question
Quantitative EEG studies of children affected by ADHD reveals

A) hyperarousal of the cortex.
B) hyperarousal of the motor systems.
C) hypoarousal of most cortical areas.
D) Both b and c are correct
Question
In normal individuals, the predominant EEG pattern during wakefulness is ________, whereas in individuals with ADHD it is ________.

A) theta; beta
B) beta; theta
C) alpha; beta
D) beta; delta
Question
Cortical hypoarousal accounts for

A) forgetfulness.
B) excessive fidgeting.
C) poor attentiveness and concentration.
D) Both a and c are correct
Question
Attentional regulation involves

A) neural activation of appropriate sensory cortices.
B) attending appropriately to specific sensory information.
C) receiving sufficient sensory information from sensory receptors to activate sensory cortices.
D) sufficient activation of the sensory thalamus.
Question
In individuals with ADHD, the thalamic reticular nucleus

A) inhibits sensory information from activating the sensory cortex.
B) is disinhibited.
C) routes sensory information to the wrong sensory cortex.
D) is not regulated by dopamine.
Question
The excessive activity observed in ADHD appears to be

A) caused by hyperarousal of the motor systems.
B) attempts by patients to self-stimulate an underaroused cortex.
C) seizure-like excitability of motor areas of the cortex.
D) unaffected by reinforcing or punishing contingencies.
Question
The dopamine-deficit theory of ADHD proposes that

A) dopamine deficits in the mesolimbic system underlie ADHD.
B) dopamine deficits in the cortex cause hypoarousal.
C) dopamine deficits in the caudate nucleus and frontal cortex may contribute to cortical hypoarousal.
D) ADHD is caused by dopamine deficiencies throughout the brain.
Question
Evidence supporting the dopamine-deficit theory of ADHD includes finding

A) an increased expression of dopamine transporters in the caudate nucleus.
B) fewer dopamine transporters in the frontal cortex.
C) decreased dopamine inhibitory control over arousal systems.
D) depressed dopamine activity in the thalamic reticular nucleus.
Question
The most widely used assessment scale for measuring treatment outcomes for ADHD is the

A) ADHD Rating Scale.
B) Brown ADHD Scales.
C) Ritvo-Freeman Real Life Rating Scale.
D) Connor's Global Index.
Question
A more objective assessment of ADHD that measures changes in cortical activity following treatment involves

A) fMRI.
B) Connor's Global Index.
C) EEG.
D) Both a and c are correct
Question
Which of the following was NOT a conclusion from the NIMH's study of treatment options for ADHD?

A) Drug abuse risk appears to decrease among stimulant-treated ADHD patients compared to their non-treated cohorts.
B) Children treated with stimulant medication showed greater improvements in academic performance and social skills compared to children in the non-medicated comparison groups.
C) Intensive behavioral treatment was far superior to induced stimulant medication.
D) Both a and b are correct
Question
Amphetamines increase the availability of DA by

A) increasing the release of NE and DA from synaptic vesicles.
B) blocking the reuptake transporter of NE.
C) causing the transporters for DA to act in reverse.
D) All of the above are correct
Question
Amphetamines cause a(n) ________ in cortical arousal by increasing ________.

A) increase; cortical dopamine activity
B) increase; NE activity in the reticular activating system
C) decrease; dopamine activity
D) Both a and b are correct
Question
NE pathways originate in the ________ and project along the ________.

A) locus coeruleus; reticular activating system
B) raphe nucleus; reticular activating system
C) locus coeruleus; cortical pathway
D) reticular activating system; thalamus
Question
Which of the following is a legitimate concern about using amphetamines to treat ADHD?

A) Their addictive potential
B) Patients selling them to others
C) Tachycardia
D) Weight gain
Question
An amphetamine overdose

A) rarely occurs.
B) can cause chronic insomnia.
C) can induce amphetamine psychosis.
D) can cause Parkinson's disease.
Question
________ is the most widely prescribed drug for ADHD.

A) Modafinil
B) Methylphenidate
C) Pemoline
D) Atomoxetine
Question
Which of the following statements best describes the drugs Ritalin and Strattera?

A) They do not have similar mechanisms of action as amphetamines do.
B) They block the reuptake of norepinephrine like amphetamines do.
C) They only increase dopamine activity.
D) They do not increase cortical arousal significantly.
Question
Modafinil increases ________ in the hypothalamus.

A) NE activity
B) histamine release
C) DA activity
D) orexin release
Question
Modafinil increases alertness in ADHD patients by

A) increasing norepinephrine activity in the reticular activating system.
B) inhibiting the thalamic reticular nucleus.
C) increasing dopamine activity in the caudate nucleus.
D) increasing histamine release in the tuberomammilary nucleus.
Question
The trade name for methylphenidate is

A) Strattera
B) Modafinil
C) Ritalin
D) Dexadrine
Question
Rett's syndrome

A) is the most common of all of the pervasive developmental disorders.
B) is a less severe and more functional form of autism.
C) occurs more frequently in males than females.
D) occurs only in females.
Question
Asperger's disorder is also known as

A) early infantile autism.
B) autistic psychopath.
C) infantile schizophrenia.
D) Rett's syndrome.
Question
Which of the following symptoms is NOT consistent with a diagnosis of autism?

A) Marked impairments in eye-to-eye contact, facial expression, and social behaviors
B) Lack of, or a marked delay in, the development of spoken language
C) Inflexibility in routines
D) Motor tics in the face
Question
A child inflicted with Asperger's disorder has essentially the same symptoms as an autistic child EXCEPT

A) restricted repetitive patterns of behavior.
B) impairments in speech development.
C) impairment in social interaction.
D) Both b and c are correct
Question
Which of the following appears to be a major cause of autism?

A) A decreased brain volume
B) Underconnectivity of major intra- and interhemispheric regions of the brain
C) An increase in the thickness of myelin in the corpus callosum
D) None of the above is correct
Question
Compared to normal control subjects, autistics demonstrate ________ activity in the ________ gyrus during sentence comprehension tasks.

A) depressed; superior temporal
B) increased; superior temporal
C) less; inferior frontal
D) Both b and c are correct
Question
The ________ genu and ________ splenium are significantly smaller in people with autism.

A) anterior; anterior
B) posterior; posterior
C) anterior; posterior
D) posterior; anterior
Question
The corpus callosum is

A) a band of connecting neurons whose axons terminate in the cingulate gyrus.
B) made up of cortical circuits that integrate intrahemispheric connections.
C) a band of interconnecting myelinated axons that unite cortical areas as well as intrahemispheric regions.
D) essential for normal intelligence.
Question
There is a strong correlation between the size of the ________ and ________.

A) genu; functional interconnectivity in the brain
B) splenium; the severity of ADHD
C) genu; the number of axons it contains
D) splenium; how well autistics respond to drug treatment
Question
Autistic spectrum disorders commonly co-occur with symptoms of all of the following EXCEPT

A) hallucinations.
B) seizures.
C) anxiety.
D) hyperactivity.
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Deck 6: Attention and Developmental Disorders: Attention-Deficithyperactivity Disorder and Autism Spectrum Disorder
1
ADHD is characterized by ________ and ________.

A) excessive talking; an inability to follow instructions
B) an inability to attend to tasks; an excessive display of motor activity and impulsivity
C) inattention to cognitive tasks; excessive talking
D) excessive fidgeting; disruptive classroom behaviors
B
2
Which of the following statements is TRUE regarding ADHD?

A) A diagnosis of ADHD usually occurs in late childhood.
B) In many cases, ADHD symptoms dissipate by early adulthood.
C) Approximately 8 percent of children under the age of ten are diagnosed with ADHD at any given time.
D) Childhood ADHD frequently occurs with other behavioral disorders.
B
3
All of the following behaviors would be consistent with an ADHD diagnosis EXCEPT

A) trouble organizing activities.
B) careless mistakes and inattention to detail.
C) excessive speech.
D) excessive concentration on a single task.
D
4
The underlying pathology of ADHD involves

A) cortical hypoarousal.
B) reticular activating system abnormalities.
C) depressed dopamine activity in the frontal cortices.
D) All of the above are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
5
Quantitative EEG studies of children affected by ADHD reveals

A) hyperarousal of the cortex.
B) hyperarousal of the motor systems.
C) hypoarousal of most cortical areas.
D) Both b and c are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
6
In normal individuals, the predominant EEG pattern during wakefulness is ________, whereas in individuals with ADHD it is ________.

A) theta; beta
B) beta; theta
C) alpha; beta
D) beta; delta
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
7
Cortical hypoarousal accounts for

A) forgetfulness.
B) excessive fidgeting.
C) poor attentiveness and concentration.
D) Both a and c are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
8
Attentional regulation involves

A) neural activation of appropriate sensory cortices.
B) attending appropriately to specific sensory information.
C) receiving sufficient sensory information from sensory receptors to activate sensory cortices.
D) sufficient activation of the sensory thalamus.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
9
In individuals with ADHD, the thalamic reticular nucleus

A) inhibits sensory information from activating the sensory cortex.
B) is disinhibited.
C) routes sensory information to the wrong sensory cortex.
D) is not regulated by dopamine.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
10
The excessive activity observed in ADHD appears to be

A) caused by hyperarousal of the motor systems.
B) attempts by patients to self-stimulate an underaroused cortex.
C) seizure-like excitability of motor areas of the cortex.
D) unaffected by reinforcing or punishing contingencies.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
11
The dopamine-deficit theory of ADHD proposes that

A) dopamine deficits in the mesolimbic system underlie ADHD.
B) dopamine deficits in the cortex cause hypoarousal.
C) dopamine deficits in the caudate nucleus and frontal cortex may contribute to cortical hypoarousal.
D) ADHD is caused by dopamine deficiencies throughout the brain.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
12
Evidence supporting the dopamine-deficit theory of ADHD includes finding

A) an increased expression of dopamine transporters in the caudate nucleus.
B) fewer dopamine transporters in the frontal cortex.
C) decreased dopamine inhibitory control over arousal systems.
D) depressed dopamine activity in the thalamic reticular nucleus.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
13
The most widely used assessment scale for measuring treatment outcomes for ADHD is the

A) ADHD Rating Scale.
B) Brown ADHD Scales.
C) Ritvo-Freeman Real Life Rating Scale.
D) Connor's Global Index.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
14
A more objective assessment of ADHD that measures changes in cortical activity following treatment involves

A) fMRI.
B) Connor's Global Index.
C) EEG.
D) Both a and c are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
15
Which of the following was NOT a conclusion from the NIMH's study of treatment options for ADHD?

A) Drug abuse risk appears to decrease among stimulant-treated ADHD patients compared to their non-treated cohorts.
B) Children treated with stimulant medication showed greater improvements in academic performance and social skills compared to children in the non-medicated comparison groups.
C) Intensive behavioral treatment was far superior to induced stimulant medication.
D) Both a and b are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
16
Amphetamines increase the availability of DA by

A) increasing the release of NE and DA from synaptic vesicles.
B) blocking the reuptake transporter of NE.
C) causing the transporters for DA to act in reverse.
D) All of the above are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
17
Amphetamines cause a(n) ________ in cortical arousal by increasing ________.

A) increase; cortical dopamine activity
B) increase; NE activity in the reticular activating system
C) decrease; dopamine activity
D) Both a and b are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
18
NE pathways originate in the ________ and project along the ________.

A) locus coeruleus; reticular activating system
B) raphe nucleus; reticular activating system
C) locus coeruleus; cortical pathway
D) reticular activating system; thalamus
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
19
Which of the following is a legitimate concern about using amphetamines to treat ADHD?

A) Their addictive potential
B) Patients selling them to others
C) Tachycardia
D) Weight gain
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
20
An amphetamine overdose

A) rarely occurs.
B) can cause chronic insomnia.
C) can induce amphetamine psychosis.
D) can cause Parkinson's disease.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
21
________ is the most widely prescribed drug for ADHD.

A) Modafinil
B) Methylphenidate
C) Pemoline
D) Atomoxetine
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
22
Which of the following statements best describes the drugs Ritalin and Strattera?

A) They do not have similar mechanisms of action as amphetamines do.
B) They block the reuptake of norepinephrine like amphetamines do.
C) They only increase dopamine activity.
D) They do not increase cortical arousal significantly.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
23
Modafinil increases ________ in the hypothalamus.

A) NE activity
B) histamine release
C) DA activity
D) orexin release
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
24
Modafinil increases alertness in ADHD patients by

A) increasing norepinephrine activity in the reticular activating system.
B) inhibiting the thalamic reticular nucleus.
C) increasing dopamine activity in the caudate nucleus.
D) increasing histamine release in the tuberomammilary nucleus.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
25
The trade name for methylphenidate is

A) Strattera
B) Modafinil
C) Ritalin
D) Dexadrine
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
26
Rett's syndrome

A) is the most common of all of the pervasive developmental disorders.
B) is a less severe and more functional form of autism.
C) occurs more frequently in males than females.
D) occurs only in females.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
27
Asperger's disorder is also known as

A) early infantile autism.
B) autistic psychopath.
C) infantile schizophrenia.
D) Rett's syndrome.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
28
Which of the following symptoms is NOT consistent with a diagnosis of autism?

A) Marked impairments in eye-to-eye contact, facial expression, and social behaviors
B) Lack of, or a marked delay in, the development of spoken language
C) Inflexibility in routines
D) Motor tics in the face
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
29
A child inflicted with Asperger's disorder has essentially the same symptoms as an autistic child EXCEPT

A) restricted repetitive patterns of behavior.
B) impairments in speech development.
C) impairment in social interaction.
D) Both b and c are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
30
Which of the following appears to be a major cause of autism?

A) A decreased brain volume
B) Underconnectivity of major intra- and interhemispheric regions of the brain
C) An increase in the thickness of myelin in the corpus callosum
D) None of the above is correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
31
Compared to normal control subjects, autistics demonstrate ________ activity in the ________ gyrus during sentence comprehension tasks.

A) depressed; superior temporal
B) increased; superior temporal
C) less; inferior frontal
D) Both b and c are correct
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
32
The ________ genu and ________ splenium are significantly smaller in people with autism.

A) anterior; anterior
B) posterior; posterior
C) anterior; posterior
D) posterior; anterior
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
33
The corpus callosum is

A) a band of connecting neurons whose axons terminate in the cingulate gyrus.
B) made up of cortical circuits that integrate intrahemispheric connections.
C) a band of interconnecting myelinated axons that unite cortical areas as well as intrahemispheric regions.
D) essential for normal intelligence.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
34
There is a strong correlation between the size of the ________ and ________.

A) genu; functional interconnectivity in the brain
B) splenium; the severity of ADHD
C) genu; the number of axons it contains
D) splenium; how well autistics respond to drug treatment
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
35
Autistic spectrum disorders commonly co-occur with symptoms of all of the following EXCEPT

A) hallucinations.
B) seizures.
C) anxiety.
D) hyperactivity.
Unlock Deck
Unlock for access to all 35 flashcards in this deck.
Unlock Deck
k this deck
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Unlock Deck
Unlock for access to all 35 flashcards in this deck.