Deck 6: Gynecologic Cancers and Disorders

Question 1

Cervical carcinoma that can be treated with cone biopsy

A)Stage 5
B)Stage 1a
C)Stage 3
D)Stage 2a
E)Stage 4a

Answer 1

Stage 1a

Question 2

The presence of atypical cells within the squamous epithelium

A)Cervical dyskaryosis
B)Nabothian follicles
C)Dysplasic dyskaryosis
D)Cervical intraepithelial neoplasia
E)Cervicitis

Answer 2

Cervical intraepithelial neoplasia

Question 3

5 year survival for someone with stage 1a cervical carcinoma

A)95%
B)10%
C)30%
D)80%
E)60%

Answer 3

95%

Question 4

Cervical carcinoma spread and staging: Invasion of the lower vagina or pelvic wall, or causing ureteric obstruction

A)Stage 1a
B)Stage 4
C)Stage 3
D)Stage 2a
E)Stage 1b

Question 5

HPV types _________ are the most significant and account for 70% of all cervical cancers

A)45 and 46
B)31 and 33
C)14 and 16
D)16 and 18
E)12 and 14

Question 6

Anovulatory infertility in PCO is due to:

A)alteration of folliculogenesis caused by dysregulation of GnRH pulse generator
B)alteration of folliculogenesis caused by adrenal & ovarian hyperandrogenism
C)alteration of folliculogenesis caused by insulin resistance
D)alteration in folliculogenesis caused by alteration of ovarian growth factors
E) alteration of folliculogenesis caused by hyper-estrogenism
F)all of the above

Question 7

Ovarian tumors which may produce chorionic gonadotrophins include :

A)Dysgerminoma
B)Teratoma
C)Choriocarcinoma
D)All of the above
E)None of the above

Question 8

Pathology of endometriosis may be explained by :

A)coelemic metaplasia
B)endometrial hyperplasia
C)retrograde menstruation
D)intraperitoneal immunologic deficit
E)lymphatic diffusion

Question 9

The cysts in Polycystic Ovarian syndrome are formed by:

A)Failure of atretic follicles to undergo apoptosis
B)Oocyte proliferation
C)Multiple corpus lutea
D)Cystic degeneration of ovarian cortex
E)none

Question 10

An ' in situ ' stage has not been officially recognized in which of the following :

A)Ovarian carcinoma
B)Endometrial carcinoma
C)Cervical carcinoma
D)Vulvar carcinoma
E)Vaginal carcinoma

Question 11

The gastrointestinal primary of a Krukenberg tumour of the ovary is most often found in the :

A)Gall bladder
B)Rectum
C)Pylorus
D)Colon
E)Small intestine

Question 12

Functional ovarian cysts include:

A)Follicular cysts.
B)Endometriomas.
C)Dermoid cysts.
D)fibromas.
E)none

Question 13

In contrast to a malignant ovarian tumor, a benign tumor has which of the following gross features?

A)Excrescences on the surface.
B)Peritoneal implants.
C)Intra-cystic papillations.
D)Free mobility.
E)Capsule rupture.

Question 14

A 54-year-old woman is found to have endometrial hyperplasia on endometrial biopsy. A functional ovarian tumor to be suspected is a:

A)Lipid cell tumor.
B)Granulosa-theca cell tumor.
C)Sertoli-Leydig yumor.
D)Muncious cystadenocarcinoma.
E)Polycystic ovary

Question 15

A uni-locular ovarian cyst measuring 4.4 cm by 4.9 cm found on routine ultrasonograrhy during the 8th week of gestation . best management for this case is

A)observation and repeated ultrasonography
B)laparoscoic aspiration of the cyst
C)immediate laparotomy and cystectomy
D)immediate laparotomy and ovariectomy
E)laparotomy and cystectomy postponed to 14 weeks

Question 16

Germ cell tumours include all the following except

A)choriocarcinoma
B)gonadoblastoma
C)endodermal sinus tumour
D)begnin cystic teratoma
E)solid teratoma

Question 17

Which is the major cause of cancer death in women?

A)Breast cancer
B)Cervical cancer
C)Endometrial cancer
D)Lung cancer
E)Ovarian cancer

Question 18

Endometrial carcinomas associated with estrogen therapy " caused by unopposed estrogen therapy " :

A)well differentiated
B)are deeply invasive
C)are sensitive to progesterone therapy
D)generally have poor prognosis
E)have high rates of reccurence

Question 19

Ovarian cancer:

A)Separate FIGO staging systems exist for epithelial and sex-cord/stromal ovarian tumors
B)Granulosa Cell Tumor has an excellent prognosis because most patients present with early-stage disease
C)Meigs' syndrome consists of ascites; hydrothorax and a malignant ovarian tumor
D)Krukenberg tumours are metastatic ovarian neoplasms originating exclusively in the stomach
E)none

Question 20

Regarding ovarian tumours

A)adenocarcinoma is more commonly bilateral than mucinous
B)the use of oral contraceptives is a risk factor for ovarian cancer
C)Sertoli-Leydig tumours of the ovary are typically estrogen secreting
D)Fat saturation MRI images are of value in diagnosing cystic teratomas
E)RI (Resistive index) values of intratumoral areas can differentiate between benign and malignant ovarian tumours

Question 21

A Krukenberg tumour is an ovarian neoplasm which :

A)Is primary in the ovary
B)Is associated with hydrothorax
C)Is secondary to any GIT cancer
D)Shows characteristic mucoid epithelial change
E)None of the above

Question 22

CA-125 is ?

A)A mucin-type glycoprtein
B)A ganglioside
C)A tumor-specific transplantation antigen
D)Useful for ovarian cancer screening in the general patient population
E)An antigen which is commonly expressed by mucinous ovarian carcinomas

Question 23

A young female came to you with complaint of oligomenorrhea ,hirsutism & weight gain ,US reveals bulky ovaries with subcapsular cysts. Most likely diagnosis is

A)ovarian cancer
B)cushing syndrome
C)PCOD
D)DM
E)PID

Question 24

A large cystic tumour is detected in a woman in routine antenatal examination. The most common complication she can encounter?

A)Torsion
B)rupture
C)hemorrhage
D)infection
E)degeneration

Question 25

A 18-year-old woman comes to the physician for an annual examination. She has no complaints. She has been sexually active for the past 2 years. She uses the oral contraceptive pill for contraception. She has depression for which she takes fluoxetine. She takes no other medications and has no allergies to medications. Her family history is negative for cancer and cardiac disease. Examination is unremarkable. Which of the following screening tests should this patient most likely have?

A)Colonoscopy
B)Mammogram
C)Pap smear
D)Pelvic ultrasound
E)Sigmoidoscopy