Deck 3: Gastric Secretion and Functioning of the Stomach

Question 1

The secretion of the intrinsic factor occurs in :

A)Parietal cells of the stomach.
B)Chief cells of the stomach.
C)Upper duodenum.
D)Beta cells of pancreas.

Answer 1

Parietal cells of the stomach.

Question 2

So-called hunger pangs :

A)Are truly due to smooth muscle spasm of the transverse colon.
B)Are associated with esophageal and pyloric contraction that coexist with an empty relaxed stomach.
C)Are more common if starvation is associated with hypoglycaemia.
D)May occur in a totally vagotomized patient.

Answer 2

Are more common if starvation is associated with hypoglycaemia.

Question 3

Basal acid output is increased with which of the following :

A)Acidification of the antrum.
B)Administration of a H? receptor antagonist.
C)Vagotomy.
D)Alkalinization of the antrum.

Answer 3

Alkalinization of the antrum.

Question 4

The cephalic phase of gastric secretion :

A)Occurs when food reach the stomch.
B)Isnot accompanied by release of GRP.
C)Is controlled by the vagi nerves.
D)Isnot blocked by injection of atropine.

Question 5

Gastric HCL secretion :

A)Is a passive process that occurs in all parts of the stomach.
B)Is stimulated by somatostatin,cimetidine & pyrenzepine.
C)Is inhibited by histamine,gastrin & acetylcholine.
D)plays a significant rule in iron absorption.

Question 6

The gastric peristalsis :

A)Depends on the basis of electric rhythm (BER).
B)Originates at the mid point of the greater curvature and increases in intensity as it sweeps towards the pylorus.
C)Is associated with a strong contraction of the antrum ant the end of each wave.
D)Always ejects the contents of the gastric antrum into the duodenum.

Question 7

All of the following statements are untrue except:

A)Peptic ulcers can be treated by anticholinesterase drugs.
B)gastric secretion in response to hypoglycemia is due to gastrin.
C)Peptic ulcers tend to heal by removal of the pyloric antrum.
D)Vomiting occurs more by smooth muscle than by skeletal muscle activity.

Question 8

Which of the following statement is true?:

A)The intrinsic factors is secreted by the parietal cells of the gastric mucosa.
B)The gastric juice can't digest the gastric mucosa because the cell membranes contain a pepsin activator.
C)The stomach normally absorbs about 30% of the ingested food.
D)The secretion of the gastric juice is associated with increased H? in the blood.

Question 9

Under normal condition, the gastric secretion is:

A)Not affected by presence of food in the stomach.
B)Stimulated by norepinephrine and inhibited bu curare.
C)Increased by distention of the stomach.
D)Maximal before food ingestion.

Question 10

About pepsins:

A)There are 5 types of exopeptidase enzymes.
B)They are secreted by endocytosis as active enzymes.
C)They are incapable of autoactivation
D)Their optimum pH of action is 1.6- 3.2.

Question 11

The stomach is a poor area for absorption primarily because:

A)Most foods are swallowed before ptyalin has a chance to breakdown starch
B)pH of the stomach is too high
C)The junction between epithelial cells presents wide space for fluid/ion movement
D)The stomach lacks villous membranes.

Question 12

Hydrochloric acid secretion:

A)Is accomplished by passive diffusion.
B)Requires the dissociation of water with subsequent exchange of the hydrogen ion for potassium ion.
C)Requires anaerobic metabolism.
D)Utilize protein molecules to neutralize OH? remaining in the secretory cells.

Question 13

A 45 years old man is found to have a condition in which the parietal cells of his stomach have been destroyed by an autoimmune mechanism. This condition is often associated with which of the following?:

A)Prenicious anaemia.
B)Gastric ulcerarion
C)Steatorrhea.
D)Protein deficiency.

Question 14

It's believed that in parietal cells of the gastric mucosa (which secrete hydrochloric acid), an active transport system is responsible for the transmembrane passage of:

A)Chloride
B)Carbon dioxide.
C)Bicarbonate.
D)Water

Question 15

Pepsin, secreted by the gastric mucosa:

A)Continues to act in the neutral medium of the duodenum.
B)Is proteolytic on the mucosal surface, in the alkaline medium provided by the mucus secreted by the surface cells of the stomach.
C)Is synthesized within the chief cells.
D)Doesnot increased in concentration in response to the mental stimuli found in the so'called cephalic phase of gastric digestion

Question 16

Acid secretion in ulcer disease can be reduced by which of the following?

A)Blockage of secretin secretion
B)Blockage of histamine H? receptors.
C)Blockage of action of pepsin
D)Treatment with antibiotics.

Question 17

The normally innervated stomach :

A)Is stimulated to secrete gastric juice when food is chewed, even if it's not swallowed
B)Can`t secrete HCL when its H? histamine receptors are blocked
C)the denervated stomach can secrete gastric juice after a meal is ingested.
D)Empties more quickly than the denervated stomach.

Question 18

Under the normal conditions, the bulk of gastric secretions are produces:

A)Before the food is ingested and while the pleasure of it's ingestion is anticipated
B)While the food stays in the stomach.
C)After the food has entered the duodenum.
D)During fasting periods.

Question 19

Mucous presents on the surface of the mucosa of the stomach,smal and large intestine is:

A)Resistant to enzymes secreted into the lumen of the gastrointestinal tract.
B)Alkaline, and thus a poor buffer for alkaline foods.
C)A non-amphoteric protein.
D)Easily removed from the surface of the stomach by the gastric secretions during the gastric phase of digestion.

Question 20

The enterogastric reflex can be elicted by which of the following?:

A)Distension of the duodenum
B)Acid chime in the duodenum.
C)Hyperosmotic chime in the duodenum.
D)All of the above

Question 21

The secretion of gastrin by the pyloric antrum ceases:

A)When the stomach is distended by a full meal
B)When the gastric mucosa contents have a pH of about 2.0
C)If histamine is injected.
D)If the vagi are stimulated.

Question 22

Gastric peristalsis:

A)Originates in the distal half of the stomach.
B)Is characterized by strong contractions of the antrum at the end of the wave.
C)Ejects all the contents of the antrum into the duodenum.
D)Decreases in intensity as it sweeps toward the pylorus.

Question 23

Which of the following substances is released from the duodenal mucosa in response to acidic gastric juice?:

A)Histamine
B)Secretin
C)Norepinephrine
D)Acetyle choline

Question 24

Which of the following hormones is involved in the initiation of the migrating motor comples?:

A)Gastrin
B)Motilin
C)Secretin
D)Cholecystokinin

Question 25

The main function of the cardiac sphincter of the stomach is to:

A)Prevent the reflux of the gastric contetnt to the esophagus
B)Facilitate storage of food on the lower part of the esophagus
C)Mix the food particles entering the stomach.
D)Control the rate of food entry into the stomach.