Deck 3: Drug Delivery Systems and Nanoparticles
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Deck 3: Drug Delivery Systems and Nanoparticles
1
Which sentence is false in the merits of SEDDS?
A)Quick onset of action
B)Increase the Drug Dose.
C)Ease of manufacture & Scale up.
D)Improvement in oral bioavailability.
A)Quick onset of action
B)Increase the Drug Dose.
C)Ease of manufacture & Scale up.
D)Improvement in oral bioavailability.
Increase the Drug Dose.
2
Which one more convenient route of administration for SEDDS.
A)Oral
B)I.V
C)I.M
D)Skin
A)Oral
B)I.V
C)I.M
D)Skin
Oral
3
Which of the following false for in example of oil in SEDDS?
A)Corn oil
B)Olive oil
C)Sesame oil
D)Rice oil
A)Corn oil
B)Olive oil
C)Sesame oil
D)Rice oil
Rice oil
4
Which of the following is false for in examples of Surfactant in SEDDS?
A)Polysorbate 20
B)Polysorbate 80
C)Span 20
D)Sorbitan monooleate
A)Polysorbate 20
B)Polysorbate 80
C)Span 20
D)Sorbitan monooleate
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5
Which of the following is false for example of co-solvent?
A)Chloroform
B)Ethanol
C)Glycerin
D)Propylene glycol
A)Chloroform
B)Ethanol
C)Glycerin
D)Propylene glycol
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6
Which are not Preferable route of administration for SEDDS?
A)Oral
B)Parenteral
C)Ophthalmic
D)Intra muscular
A)Oral
B)Parenteral
C)Ophthalmic
D)Intra muscular
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7
Mucoadhesive drug delivery system is a part of ___________delivery system?
A)Control
B)Sustained
C)Prolong
D)Target
A)Control
B)Sustained
C)Prolong
D)Target
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8
Drug loading capacity of MDDS.
A)Low
B)High
C)Very low
D)Medium
A)Low
B)High
C)Very low
D)Medium
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9
Which theory use for the attractive electrostatic forces between glycoprotein Mucin network & the bio adhesive/ mucoadhesive material?
A)Electronic theory
B)Wetting theory
C)Adsorption theory
D)Diffusion theory
A)Electronic theory
B)Wetting theory
C)Adsorption theory
D)Diffusion theory
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10
Which theory use for Physical entanglement of Mucin strands and flexible polymer chains.
A)Wetting theory
B)Adsorption theory
C)Diffusion theory
D)Fracture theory
A)Wetting theory
B)Adsorption theory
C)Diffusion theory
D)Fracture theory
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11
Which route is not use for MDDS?
A)Nasal
B)Rectal
C)Oral
D)Buccal
A)Nasal
B)Rectal
C)Oral
D)Buccal
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12
Which polymers is not included in the semisynthetic class?
A)Chitosan
B)Gelatin
C)Pectin
D)Carbopol
A)Chitosan
B)Gelatin
C)Pectin
D)Carbopol
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13
Which polymers is not soluble in water?
A)PVP
B)CMC
C)PEG
D)HPMC
A)PVP
B)CMC
C)PEG
D)HPMC
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14
Which polymers are not having charge?
A)Starch
B)Amino dextran
C)Pectin
D)Sodium CMC
A)Starch
B)Amino dextran
C)Pectin
D)Sodium CMC
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15
Which sentence is false in merits of MDDS?
A)Targeting & localization of the dosage form at a specific site
B)Painless administration
C)Low enzymatic activity & avoid of first pass metabolism
D)Some patient suffers unpleasant feeling
A)Targeting & localization of the dosage form at a specific site
B)Painless administration
C)Low enzymatic activity & avoid of first pass metabolism
D)Some patient suffers unpleasant feeling
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16
Which are the following not including in semisolid dosage form in MDDS?
A)Gel & ointment
B)Tablet
C)Films
D)Patches
A)Gel & ointment
B)Tablet
C)Films
D)Patches
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17
What is the characteristics of mucoadhesive systems?
A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Usage of bio adhesive polymer
D)Use of high or low density pellets
A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Usage of bio adhesive polymer
D)Use of high or low density pellets
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18
Mucoadhesive are including in which drug delivery system?
A)Target drug delivery system
B)Control drug delivery system
C)Prolong drug delivery system
D)Diffusion drug delivery system
A)Target drug delivery system
B)Control drug delivery system
C)Prolong drug delivery system
D)Diffusion drug delivery system
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19
Loading capacity of Mucoadhesive drug delivery system?
A)High
B)Poor
C)Medium
D)Very Poor
A)High
B)Poor
C)Medium
D)Very Poor
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20
Howmany water percentage are present in Mucoadhesive drug delivery system?
A)90 %
B)80%
C)95 %
D)101%
A)90 %
B)80%
C)95 %
D)101%
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21
Howmany nontechnology based product approved for clinical use?
A)20
B)24
C)30
D)10
A)20
B)24
C)30
D)10
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22
What are the size of nanoparticles?
A)10 - 100 nm
B)1 - 100 nm
C)10 - 1000 nm
D)None
A)10 - 100 nm
B)1 - 100 nm
C)10 - 1000 nm
D)None
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23
Which of the following is a characteristic of nanoparticles?
A)Free flowing powders
B)Aqueous solutions
C)Control drug release by partitioning the drug from the oil
D)Size range 1 -100 nm
A)Free flowing powders
B)Aqueous solutions
C)Control drug release by partitioning the drug from the oil
D)Size range 1 -100 nm
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24
Nanoparticles are dived in ………….. class ?
A)3
B)2
C)4
D)0
A)3
B)2
C)4
D)0
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25
Which are protein is includes in natural protein ?
A)PECL
B)PLA
C)Gelatin
D)PMMA
A)PECL
B)PLA
C)Gelatin
D)PMMA
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