Deck 5: Gene Expression, Molecular Genetics, DNA Technology and Genomics

Question 1

Which of the following products is not made in E. coli?

A) insulin
B) hepatitis b vaccine
C) human growth hormone
D) cellulase

Answer 1

hepatitis b vaccine

Question 2

What is Ti plasmid used for?

A) diagnosing viruses
B) introducing new genes into soil bacterium
C) introducing DNA into human bacterium
D) testing if an organism is genetically modified

Answer 2

introducing new genes into soil bacterium

Question 3

In Canada, foods that are GMOs ________ be labelled specifically to state that they are.

A) legally must
B) do not need to
C) in some cases must
D) are preferred by the government to

Answer 3

do not need to

Question 4

Approximately what percentage of the human genome is identical to that of a chimpanzee?

A) 50.0%
B) 62.3%
C) 92.0%
D) 98.8%

Question 5

In addition to the percentage of the human genome that is identical to that of a chimpanzee, a further ________ difference is because of insertions or deletions of the regions in the genome of chimpanzees or humans.

A) 15%
B) 7.5%
C) 5.3%
D) 2.7 %

Question 6

After reading the paragraph below, answer the question that follows.
Gene therapy is a relatively new approach to treating inherited disorders. In effect, a good, working copy of the affected gene is introduced into multiple cells on an expression vector (typically a virus). The good gene is incorporated into the genome of each cell, thus providing the information missing due to the host cell's mutated gene.

-Which of the following statements regarding gene therapy is incorrect?

A) Successful infection of the good gene into tissue resident stem cells will promote the gradual replacement of 'bad' cells with 'good' ones, i.e. those that have a good copy of the gene.
B) Successful infection of the good gene into post-mitotic tissue cells will require that a great many individual cells take up and incorporate the good gene.
C) Once the good gene is incorporated into a cell's genome, there is effectively no mechanism to remove it.
D) A 'bad' gene product can still overcome the benefit of the 'good' gene and this is called a dominant negative effect.

Question 7

________ can regulate hemoglobin mRNA to be translated only under certain conditions.

A) White blood cells
B) RNA
C) Red blood cells
D) mRNA

Question 8

What types of bonds hold together nucleotides in DNA?

A) hydrogen bonds
B) covalent bonds
C) noncovalent bonds
D) dipole-dipole bonds

Question 9

After reading the paragraph below, answer the question that follows.
Mitochondria contain their own small genome that contains information to make ribosomal RNAs, transfer RNAs, and a few proteins. Interestingly, the mitochondrial genome has a different genetic code than nuclear DNA. Occasionally, mitochondrial DNA escapes the mitochondrial compartment and enters the cytosol and nucleus.

-What would happen to the extra mitochondrial DNA inside of the cell's nucleus?

A) It could be transcribed and translated into functional proteins.
B) It could be transcribed and translated into nonfunctional proteins.
C) It could be transcribed but not translated.
D) It could not be transcribed.