Deck 6: Cancer: DNA Synthesis, Mitosis, and Meiosis
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Deck 6: Cancer: DNA Synthesis, Mitosis, and Meiosis
1
What type of reproduction includes the binary fission used by single-celled bacteria to produce genetically identical daughter cells?
A) sexual reproduction
B) asexual reproduction
C) fertilization
D) condensation
A) sexual reproduction
B) asexual reproduction
C) fertilization
D) condensation
B
2
What enzyme assists in DNA synthesis? (two words)
DNA polymerase
3
What process occurs when cancer cells detach from tumors and spread to other parts of the body?
A) angiogenesis
B) carcinogenesis
C) metastasis
D) mutagenesis
A) angiogenesis
B) carcinogenesis
C) metastasis
D) mutagenesis
C
4
Which feature is found in DNA?
A) Adenine (A) forms a base pair with cytosine (C).
B) The backbone of each strand is composed of alternating sugar and phosphate groups.
C) Complementary strands are held together by ionic bonds.
D) DNA remains condensed in a short linear form both before and after cell division.
A) Adenine (A) forms a base pair with cytosine (C).
B) The backbone of each strand is composed of alternating sugar and phosphate groups.
C) Complementary strands are held together by ionic bonds.
D) DNA remains condensed in a short linear form both before and after cell division.
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5
What term describes nucleotides in opposing strands of DNA that bind to each other?
A) semiconservative
B) complementary
C) conjoined
D) sister chromatids
A) semiconservative
B) complementary
C) conjoined
D) sister chromatids
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6

How do smoking and alcohol consumption affect cancer risk?
A) Smoking combined with alcohol consumption results in greater cancer risk.
B) Drinking alcohol results in greater cancer risk than smoking.
C) Smoking or drinking alcohol result in similar cancer risk.
D) Smoking results in twice the cancer risk of drinking.
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7
What are the two halves of a duplicated chromosome called?
A) alleles
B) centromeres
C) homologous chromosomes
D) sister chromatids
A) alleles
B) centromeres
C) homologous chromosomes
D) sister chromatids
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8
Which substance is not a known carcinogen?
A) certain viruses
B) ultraviolet light
C) cigarette smoke
D) pet dander
A) certain viruses
B) ultraviolet light
C) cigarette smoke
D) pet dander
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9
Which organs are often analyzed for cancer cells to determine whether the tumor has metastasized?
A) liver
B) lymph node
C) pancreas
D) ovary
A) liver
B) lymph node
C) pancreas
D) ovary
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10
In a certain species of animal, 33% of the bases in its DNA are A. What percent of the bases are C?
A) 8.5%
B) 17%
C) 33%
D) 34%
A) 8.5%
B) 17%
C) 33%
D) 34%
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11
Which term describes a cancerous tumor?
A) benign
B) carcinogenic
C) malignant
D) oncogenic
A) benign
B) carcinogenic
C) malignant
D) oncogenic
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12
What is the process by which cells of a malignant tumor can break away and start new cancers at distant locations?
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13
Why is DNA replication considered semiconservative?
A) DNA is created from only four of nine available nucleotides.
B) The DNA molecule includes a parental strand and newly created DNA strand.
C) DNA is not just one strand but two complementary strands.
D) DNA is divided into a top half and a bottom half before replicating.
A) DNA is created from only four of nine available nucleotides.
B) The DNA molecule includes a parental strand and newly created DNA strand.
C) DNA is not just one strand but two complementary strands.
D) DNA is divided into a top half and a bottom half before replicating.
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14
What is the region in the middle of a replicated chromosome that connects sister chromatids?
A) centriole
B) centromere
C) karyotype
D) chromatid
A) centriole
B) centromere
C) karyotype
D) chromatid
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15
In a bacterial species, 20% of the bases in its DNA are C. What percent of the bases are G?
A) 80%
B) 40%
C) 20%
D) 10%
A) 80%
B) 40%
C) 20%
D) 10%
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16
If a double-stranded DNA molecule is like a twisted rope ladder with handrails and steps, what would the steps in the ladder represent?
A) phosphate groups
B) sugar (deoxyribose) molecules
C) nitrogenous bases
D) DNA polymerase
A) phosphate groups
B) sugar (deoxyribose) molecules
C) nitrogenous bases
D) DNA polymerase
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17
What are the two halves of a duplicated chromosome? (two words)
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18
Consider a strand of DNA with the sequence GAATTCGGCA. What is the sequence of the complementary strand?
A) ACGGCTTAAG
B) AGGCCTAATG
C) CTTAAGCCGT
D) GAATTCGGCA
A) ACGGCTTAAG
B) AGGCCTAATG
C) CTTAAGCCGT
D) GAATTCGGCA
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19
What term describes a harmless, noncancerous or precancerous tumor?
A) benign
B) carcinogenic
C) malignant
D) metastatic
A) benign
B) carcinogenic
C) malignant
D) metastatic
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20

DNA polymerase moves along the length of the unwound helix, starting at the end of one strand and finishing at the end of the other strand. As shown in this figure, what is the result of this phenomenon?
A) One resulting double strand of DNA is composed of new DNA, and one is composed of parental DNA.
B) Free nucleotides are added to one strand of parental DNA but not to the other.
C) The DNA polymerase moves toward the unwound helix on one strand of DNA and away from it on the other strand.
D) DNA polymerase is destroyed as it binds nucleotides to form each daughter strand.
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21
During which phase of the cell cycle does the cytoplasm divide?
A) G1 phase
B) S phase
C) mitosis
D) cytokinesis
A) G1 phase
B) S phase
C) mitosis
D) cytokinesis
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22
Why do chromosomes resemble the letter X when viewed during metaphase?
A) Because they all appear and function as X chromosomes at that stage.
B) Because there are two sister chromatids joined at a point in the middle (the centromere).
C) Because microtubules encircle and attach pairs of chromosomes to each other at the centromere.
D) Because each X-shaped structure is actually four chromosomes joined at the centromere.
A) Because they all appear and function as X chromosomes at that stage.
B) Because there are two sister chromatids joined at a point in the middle (the centromere).
C) Because microtubules encircle and attach pairs of chromosomes to each other at the centromere.
D) Because each X-shaped structure is actually four chromosomes joined at the centromere.
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23
What is the correct order of events in mitosis?
A) anaphase, metaphase, prophase, telophase
B) anaphase, prophase, metaphase, telophase
C) metaphase, prophase, telophase, anaphase
D) prophase, metaphase, anaphase, telophase
A) anaphase, metaphase, prophase, telophase
B) anaphase, prophase, metaphase, telophase
C) metaphase, prophase, telophase, anaphase
D) prophase, metaphase, anaphase, telophase
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24
What gene encodes a protein that will inhibit cell division?
A) angiogenesis inhibitor
B) growth factor
C) oncogene
D) tumor-suppressor gene
A) angiogenesis inhibitor
B) growth factor
C) oncogene
D) tumor-suppressor gene
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25
What is the correct order of events in the cell cycle?
A) G₁, G₂, S, mitosis, cytokinesis
B) G₁, S, G₂, mitosis, cytokinesis
C) S, G₁, G₂, cytokinesis, mitosis
D) S, G₁, G₂, mitosis, cytokinesis
A) G₁, G₂, S, mitosis, cytokinesis
B) G₁, S, G₂, mitosis, cytokinesis
C) S, G₁, G₂, cytokinesis, mitosis
D) S, G₁, G₂, mitosis, cytokinesis
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26
Which type of cell division produces daughter cells that are identical to the original cell?
A) meiosis in animals
B) meiosis in plants
C) mitosis in animals
D) meiosis in bacteria
A) meiosis in animals
B) meiosis in plants
C) mitosis in animals
D) meiosis in bacteria
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27
In which phase of the cell cycle are cells most often found?
A) interphase
B) prophase
C) metaphase
D) anaphase
A) interphase
B) prophase
C) metaphase
D) anaphase
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28
What would result if a cell underwent mitosis but did not complete cytokinesis?
A) one cell with one nucleus containing twice the normal number of chromosomes
B) one cell with two nuclei
C) two daughter cells with no nucleus
D) two daughter cells with too few chromosomes
A) one cell with one nucleus containing twice the normal number of chromosomes
B) one cell with two nuclei
C) two daughter cells with no nucleus
D) two daughter cells with too few chromosomes
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29
During which part of mitosis does the nuclear envelope break down?
A) anaphase
B) metaphase
C) prophase
D) telophase
A) anaphase
B) metaphase
C) prophase
D) telophase
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30
During which phase of mitosis are the replicated chromosome aligned in the middle of the cell?
A) prophase
B) anaphase
C) metaphase
D) telophase
A) prophase
B) anaphase
C) metaphase
D) telophase
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31
During which process would a cell plate form?
A) cytokinesis in an animal cell
B) cytokinesis in a plant cell
C) mitosis in an animal cell
D) mitosis in a plant cell
A) cytokinesis in an animal cell
B) cytokinesis in a plant cell
C) mitosis in an animal cell
D) mitosis in a plant cell
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32
During which phase of mitosis do sister chromatids separate to opposite poles of the cell?
A) prophase
B) anaphase
C) metaphase
D) telophase
A) prophase
B) anaphase
C) metaphase
D) telophase
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33
Which carbohydrate forms the cell wall during cytokinesis in plant cells?
A) cellulose
B) sucrose
C) glucose
D) lactose
A) cellulose
B) sucrose
C) glucose
D) lactose
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34

According to the diagram, what structures are connected to the centrioles by the microtubules during mitosis?
A) the nuclear envelope
B) uncondensed DNA
C) cytoplasm
D) centromeres
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35
During the metaphase checkpoint, what information is being checked by the cell?
A) if it is large enough to divide
B) if its DNA has been replicated correctly
C) if its chromosomes are properly attached to microtubules
D) if there are sufficient nutrients available
A) if it is large enough to divide
B) if its DNA has been replicated correctly
C) if its chromosomes are properly attached to microtubules
D) if there are sufficient nutrients available
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36
What is the relationship between proto-oncogenes and oncogenes?
A) Oncogenes may develop into cancer-causing proto-oncogenes as a result of synergism.
B) Oncogenes prevent proto-oncogenes from encoding proteins for cell division.
C) Proto-oncogenes may develop into cancer-causing oncogenes as a result of mutations.
D) Proto-oncogenes allow oncogenes to encode proteins that prevent cell division.
A) Oncogenes may develop into cancer-causing proto-oncogenes as a result of synergism.
B) Oncogenes prevent proto-oncogenes from encoding proteins for cell division.
C) Proto-oncogenes may develop into cancer-causing oncogenes as a result of mutations.
D) Proto-oncogenes allow oncogenes to encode proteins that prevent cell division.
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37
Which phase occurs during mitosis?
A) first gap phase
B) metaphase
C) second gap phase
D) S phase
A) first gap phase
B) metaphase
C) second gap phase
D) S phase
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38
Which is a common feature of cancer cells?
A) anchorage dependence
B) contact inhibition
C) metastasis
D) controlled division
A) anchorage dependence
B) contact inhibition
C) metastasis
D) controlled division
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39
During which phase of the cell cycle do most organelles duplicate?
A) prophase of mitosis
B) telophase of mitosis
C) the S phase of interphase
D) the G1 phase of interphase
A) prophase of mitosis
B) telophase of mitosis
C) the S phase of interphase
D) the G1 phase of interphase
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40
Which cells would spend the most time in interphase?
A) skin cells on the hands
B) epithelial cells lining the intestine
C) nerve cells in the brain
D) mucous membrane cells in the mouth
A) skin cells on the hands
B) epithelial cells lining the intestine
C) nerve cells in the brain
D) mucous membrane cells in the mouth
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41
During which stage of meiosis do homologous chromosomes separate?
A) meiosis I
B) meiosis II
C) interphase
D) cytokinesis
A) meiosis I
B) meiosis II
C) interphase
D) cytokinesis
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42
Which statement describes human sperm or egg cells?
A) They are produced by the process of mitosis.
B) They have one copy of each chromosome.
C) They have two copies of each chromosome.
D) They are genetically identical to all gametes made by a person.
A) They are produced by the process of mitosis.
B) They have one copy of each chromosome.
C) They have two copies of each chromosome.
D) They are genetically identical to all gametes made by a person.
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43
Tetraploid organisms have four copies of each chromosome instead of the two copies that humans have. How many copies of each chromosome end up in a gamete produced by a tetraploid organism?
A) 1
B) 2
C) 3
D) 4
A) 1
B) 2
C) 3
D) 4
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44
What is the surgical removal of cells, tissue, or fluid that will be analyzed for cancerous cells?
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45
During which meiotic phase does crossing over occur?
A) anaphase I of meiosis I
B) anaphase II of meiosis II
C) prophase I of meiosis I
D) prophase II of meiosis II
A) anaphase I of meiosis I
B) anaphase II of meiosis II
C) prophase I of meiosis I
D) prophase II of meiosis II
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46
When do sister chromatids separate?
A) meiosis I and meiosis II
B) meiosis I and mitosis
C) mitosis and cytokinesis
D) meiosis II and mitosis
A) meiosis I and meiosis II
B) meiosis I and mitosis
C) mitosis and cytokinesis
D) meiosis II and mitosis
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47
What observations would be made by a scientist viewing cancer cells under a microscope?
A) orderly rows of cells
B) cells that are much smaller than normal cells
C) large growths containing fluid
D) disorganized cells
A) orderly rows of cells
B) cells that are much smaller than normal cells
C) large growths containing fluid
D) disorganized cells
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48
What are the members of a pair of nonsex chromosomes?
A) alleles
B) diploids
C) gametes
D) homologous chromosomes
A) alleles
B) diploids
C) gametes
D) homologous chromosomes
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49
How does radiation therapy work on cancer cells?
A) Radiation limits microtubule formation, affecting chromosome alignment during mitosis.
B) Radiation causes tumor cells to stick together, making them easier to remove.
C) Radiation damages DNA in cells so that cells can no longer grow and divide.
D) Radiation makes cancer cells divide so fast that they may develop extra mutations and die.
A) Radiation limits microtubule formation, affecting chromosome alignment during mitosis.
B) Radiation causes tumor cells to stick together, making them easier to remove.
C) Radiation damages DNA in cells so that cells can no longer grow and divide.
D) Radiation makes cancer cells divide so fast that they may develop extra mutations and die.
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50
What is meant by the "multiple hit" model of cancer?
A) Most cancer-causing mutations are passed on to future generations.
B) Most cancers occur in many different tissues simultaneously.
C) Multiple mutations are required to cause most forms of cancer.
D) A person gets cancer only if both of his or her parents had cancer.
A) Most cancer-causing mutations are passed on to future generations.
B) Most cancers occur in many different tissues simultaneously.
C) Multiple mutations are required to cause most forms of cancer.
D) A person gets cancer only if both of his or her parents had cancer.
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51
What type of normal human cell contains 44 autosomes and two X chromosomes?
A) egg cell
B) somatic cell of a female
C) somatic cell of a male
D) sperm cell
A) egg cell
B) somatic cell of a female
C) somatic cell of a male
D) sperm cell
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52
What are specialized cells (egg cells and sperm cells, for example) used for sexual reproduction?
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53
What are genes that are located on the same chromosome and move together to the same gamete?
A) alleles
B) diploid genes
C) homologous genes
D) linked genes
A) alleles
B) diploid genes
C) homologous genes
D) linked genes
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54
Which feature of cancer cells is targeted by most forms of chemotherapy?
A) anchorage independence
B) cell division
C) invasiveness of surrounding tissues
D) metastasis
A) anchorage independence
B) cell division
C) invasiveness of surrounding tissues
D) metastasis
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55
What type of normal human cell contains 22 autosomes and a Y chromosome?
A) egg cell
B) somatic cell of a female
C) somatic cell of a male
D) sperm cell
A) egg cell
B) somatic cell of a female
C) somatic cell of a male
D) sperm cell
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56
How does crossing over increase genetic diversity?
A) Crossing over increases the different combinations of genes present in a gamete.
B) Crossing over allows specific genes to travel together on one chromosome.
C) Crossing over increases the incidence of mutations in genes.
D) Crossing over prevents the inheritance of harmful mutations.
A) Crossing over increases the different combinations of genes present in a gamete.
B) Crossing over allows specific genes to travel together on one chromosome.
C) Crossing over increases the incidence of mutations in genes.
D) Crossing over prevents the inheritance of harmful mutations.
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57
What are the different versions of the same gene?
A) alleles
B) diploids
C) homologous chromosomes
D) sister chromatids
A) alleles
B) diploids
C) homologous chromosomes
D) sister chromatids
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58
What are the places in the cell cycle where proteins survey the cell to make sure that conditions for a favorable cell division have been met?
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