Deck 16: Pancreas

Question 1

A 65-year-old man complains of vague upper abdominal pain, weight loss, and loose fatty stools. Radiographs show visible calcifications within the pancreas. These findings are most consistent with a diagnosis of which of the following disorders?

A) Ductal carcinoma of the pancreas
B) Acinar cell carcinoma of the pancreas
C) Islet cell carcinoma
D) Chronic pancreatitis
E) Pancreatic pseudocyst

Answer 1

Chronic pancreatitis

Question 2

Which of the following is the most common cause of acute pancreatitis?

A) Alcohol
B) Thiazide diuretics
C) Viruses
D) Trauma
E) Vascular thrombosis

Answer 2

Alcohol

Question 3

Which of the following genes is the most frequently mutated oncogene in ductal adenocarcinoma of the pancreas?

A) p53
B) K-RAS
C) MYC
D) RB1
E) SMAD4

Answer 3

K-RAS

Question 4

Hereditary pancreatitis is most likely to be found in persons harboring the mutation of which of the following genes?

A) α₁-Antitrypsin
B) Amylase
C) Cationic trypsinogen
D) Enterokinase
E) Alkaline phosphatase