Deck 13: Effector Mechanisms of Humoral Immunity

Question 1

Matching
For each of the following descriptions in questions , select the Fc receptor (A-G) that best matches it.
High-affinity Ig receptor on mast cells important in immediate hypersensitivity reactions

A)
B)
C)
D)
E)
F)
G)

Answer 1

Question 2

For each of the functions described in questions , select the complement system protein (A-F) that best matches it.
This complement fragment is a component of the membrane attack complex.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a

Answer 2

C5b

Question 3

For each of the functions described in questions , select the complement system protein (A-F) that best matches it.
Produced by C3 convertases, this opsonin promotes phagocytosis of microbes.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a

Answer 3

C3b

Question 4

Which of the following anatomic regions is normally protected from pathogens only by humoral immune responses and not by cell-mediated immune responses?

A) Skin
B) Intestinal lumen
C) Intestinal epithelium
D) Central nervous system
E) Spleen

Question 5

Matching
For each of the following descriptions in questions , select the Fc receptor (A-G) that best matches it.
Low-affinity Ig receptor on natural killer cells that mediates antibody-dependent cell-mediated cytotoxicity

A)
B)
C)
D)
E)
F)
G)

Question 6

Matching
For each of the following descriptions in questions , select the Fc receptor (A-G) that best matches it.
High-affinity Ig receptor on macrophages and neutrophils important for phagocytosis and activation

A)
B)
C)
D)
E)
F)
G)

Question 7

For each of the functions described in questions , select the complement system protein (A-F) that best matches it.
This complement fragment is a chemoattractant for neutrophils.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a

Question 8

For each of the functions described in questions , select the complement system protein (A-F) that best matches it.
Generated by factor I-mediated proteolysis, this complement fragment binds to complement receptor 2 (CR2) on B cells and enhances B cell activation.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a

Question 9

Matching
For each of the following descriptions in questions , select the Fc receptor (A-G) that best matches it.
Ig receptor on B cells that mediates feedback inhibition

A)
B)
C)
D)
E)
F)
G)

Question 10

For each of the functions described in questions , select the complement system protein (A-F) that best matches it.
Generated by factor I-mediated proteolysis, this opsonizing complement fragment binds to CR3 on phagocytes.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a