Deck 12: Neural Crest

Question 1

Which is derived from cranial,but not trunk,neural crest?

A)Sensory ganglia
B)Wall of aorta
C)Schwann cells
D)Pigment cells
E)Parasympathetic ganglia

Answer 1

B

Question 2

Which of the following conditions is most closely associated with a disturbance of neural crest?

A)Anal atresia
B)Meckel's diverticulum
C)Omphalocele
D)Volvulus
E)Aganglionic megacolon

Answer 2

E

Question 3

Which of the following cell and tissue types arises from cranial,but not trunk,neural crest cells?

A)Sensory ganglia
B)Adrenal medulla
C)Melanocytes
D)Schwann cells
E)None of the above

Answer 3

E

Question 4

Which of the following tissue types differentiates from cranial neural crest,but not trunk neural crest cells?

A)Parasympathetic ganglia
B)Schwann cells
C)Smooth muscle
D)Melanocytes
E)Adrenal medullary cells

Question 5

Neural crest cells that are breaking free from the neural epithelium express ______________.

A)Nodal
B)Lim-1
C)Chordin
D)Noggin
E)Slug

Question 6

Derivatives of neural crest cells include all of the following except ___________________:

A)Melanocytes
B)Chromaffin cells
C)Sensory neurons
D)Sympathetic neurons
E)Epidermis

Question 7

A newborn exhibits multiple congenital defects including a cleft palate,deafness,ocular hypertelorism,and a white forelock but otherwise dark hair on his head.The probable diagnosis is ________________________:

A)von Recklinghausen's disease
B)Hirschsprung's disease
C)Klinefelter syndrome
D)Arnold-Chiari malformation
E)Waardenburg syndrome

Question 8

The coordinated pattern of migration of neural crest cells from rhombomere 2 to the first pharyngeal arch,rhombomere 4 into the second arch,and rhombomere 6 into the third arch is correlated with precise expression patterns of which of the Hox gene families?

A)Hox-1 (Hox A)
B)Hox-2 (Hox B)
C)Hox-3 (Hox C)
D)Hox-4 (Hox D)

Question 9

Which of the following is a poor substrate for migrating neural crest cells?

A)Laminin
B)Chondroitin sulfate
C)Fibronectin
D)Type IV collagen
E)Hyaluronic acid

Question 10

Neural crest from the trunk region contributes to all of the following structures except ______________________.

A)Sensory ganglia
B)Sympathetic ganglia
C)Melanocytes
D)Adrenal medulla
E)Cartilage

Question 11

Which of the following might be associated with von Recklinghausen's disease?

A)Café au lait spots
B)Neurofibromas
C)Gigantism of the limb
D)All of the above

Question 12

Neural crest cells arise from the ______________.

A)Somite
B)Zone of polarizing activity
C)Neural tube
D)Splanchnic mesoderm
E)Yolk sac endoderm

Question 13

Which of these neural crest derivatives is formed only from cranial neural crest?

A)Melanocytes
B)Sensory ganglion cells
C)Cartilage
D)Satellite cells of sensory ganglia
E)Adrenal medulla

Question 14

Which of the following is a derivative of cranial,but not trunk,neural crest?

A)Sensory ganglia
B)Dermis
C)Melanocytes
D)Schwann cells
E)Autonomic ganglia