Deck 1: Cells and Organs of the Immune System

Question 1

Monocytes enter tissue and develop into:

A) PMNs
B) Mast cells
C) Plasma cells
D) Macrophages

Answer 1

Macrophages

Question 2

Which of the following congenital disorders results in defects in the thymus?
I- Nezelof Syndrome
II- DiGeorge Syndrome
III- Leukocyte Adhesion Deficiency

A) I only
B) III only
C) I and II
D) II and III
E) I, II, and III

Answer 2

I and II

Question 3

Monocytes are primarily located in the:

A) Liver
B) Blood
C) Spleen
D) Lymph nodes

Answer 3

Blood

Question 4

The granules in polymorphonuclear leukocytes (PMNs) play which of the following roles in the immune response?

A) Assist in antibody production
B) Kill cells infected with viruses
C) Destroy phagocytosed bacteria
D) Aid cells in ingestion of bacteria

Question 5

Aged red blood cells are destroyed by macrophages in the:

A) Tonsils
B) Lymph nodes
C) Peyer's patches
D) Splenic red pulp

Question 6

Phagocytosis is the main function of which of the following cell types?

A) NK cells
B) Basophils
C) Eosinophils
D) Macrophages

Question 7

Immature thymocytes begin their initial cycle of proliferation in:

A) The thymic cortex
B) Hassall's corpuscles
C) The germinal center
D) The lymph node medulla

Question 8

Which cell type contains granules that are specific for killing parasites?

A) PMNs
B) Eosinophils
C) Macrophages
D) Large granular lymphocytes

Question 9

In positive selection, thymocytes undergo apoptosis when:
I-They do not interact with MHC molecules
II-They bind to MHC molecules with high affinity
III-They bind to MHC molecules with low affinity

A) I only
B) III only
C) I and II
D) II and III
E) I, II, and III

Question 10

The __________________ serves as a filter to trap infections in the tissues.

A) Spleen
B) Thymus
C) Bone marrow
D) Lymph system

Question 11

The main function of _______________ is to ingest and destroy bacteria.

A) B cells
B) Eosinophils
C) Natural killer (NK) cells
D) Polymorphonuclear leukocytes (PMNs)

Question 12

As a result of leukocyte adhesion deficiency, white blood cells cannot:

A) Present antigen
B) Release granules
C) Perform diapedesis
D) Phagocytose pathogens

Question 13

All T cells express which of the following CD markers?

A) CD3
B) CD4
C) CD8
D) CD16

Question 14

Which of the following cells is important for killing virus-infected cells?

A) NK cells
B) Basophils
C) Monocytes
D) Plasma cells

Question 15

Hematopoiesis is the:

A) Development of blood cells
B) Development of cancer cells
C) Development of immune cells
D) Development of immune response

Question 16

B cells that are actively proliferating are located in the ________________ of the lymph node.

A) Mantle layer
B) Germinal center
C) Medullary region
D) Paracortical region

Question 17

Development of which cell type is impaired in DiGeorge syndrome?
I- T cells
II- B cells
III- NK cells

A) I only
B) III only
C) I and II
D) II and III
E) I, II, and III

Question 18

What role does the T helper 1 (Th1) subset play in the immune response?

A) Inhibits viral replication
B) Causes target cell death of infected cells
C) Assists B cells in the production of antibody
D) Generates inflammatory responses to pathogens

Question 19

The role of microfold (M) cells is to:

A) Trap antigens
B) Kill pathogens
C) Present antigens
D) Produce antibodies

Question 20

The main purpose of diapedesis is to:

A) Aid neutrophils in granule release
B) Capture antigens for presentation to lymphocytes
C) Allow immune cells to travel to the site of infection
D) Activate macrophages for more effective phagocytosis