Deck 5: Antigen Presenting Cells

Question 1

The _________________ is the vacuole in a B cell where an endocytosed antigen is located.

A) Iccosome
B) Endosome
C) Phagosome
D) Phagolysosome

Answer 1

Endosome

Question 2

Dendritic cells are important parts of the immune response because they are:

A) Able to produce antibody
B) Circulating in the blood waiting for antigen
C) Able to kill tumor cells and virally-infected cells
D) Located in areas that are likely sites of pathogen entry

Answer 2

Located in areas that are likely sites of pathogen entry

Question 3

Which of the following cells are only able to present antigen under special circumstances, and as a result are called amateur antigen presenting cells (APCs)?
I. B cells
II. Dendritic cells
III. Endothelial cells

A) I only
B) III only
C) I and II
D) II and III
E) I, II, and III

Answer 3

III only

Question 4

Which type of dendritic cell activates both NK cells and CD8 T cells (CTLs) in response to a viral infection?

A) Follicular dendritic cells
B) Interstitial dendritic cells
C) Plasmacytoid dendritic cells
D) Interdigitating dendritic cells

Question 5

The largest reservoir of interstitial dendritic cells is located in the:

A) Eye
B) Skin
C) Brain
D) Tonsils

Question 6

Primed dendritic cells are a potential treatment for:
I- HIV
II- Psoriasis
III- Cancer

A) I only
B) III only
C) I and II
D) II and III
E) I, II, and III

Question 7

Which type of dendritic cell does not present antigen, but instead aids B cell maturation into plasma cells?

A) Langerhans cells
B) Follicular dendritic cells
C) Interstitial dendritic cells
D) Plasmacytoid dendritic cells

Question 8

The purpose of the invariant chain is to:

A) Aid in receptor-mediated endocytosis in B cells
B) Guide MHC class II molecules to the endosome
C) Release antigen to stimulate memory cell formation
D) Aid in movement of the early endosome to a late endosome

Question 9

After a Langerhans cell captures antigen, it travels to the:

A) Spleen
B) Lymph node
C) Bone marrow
D) Surface of the skin

Question 10

Kupffer cells are a type of macrophage located in the:

A) Liver
B) Bone
C) Brain
D) Connective tissue