Deck 7: Treatment of Schizophrenia and Psychoses

Question 1

Which of the following is not an example of a "traditional" neuroleptic?

A)Chlorpromazine
B)Haloperidol
C)Thiothixene
D)Risperidone

Answer 1

Risperidone

Question 2

_____ is a traditional neuroleptic with a reduced bioavailability.

A)Haloperidol intravenous (IV)injection
B)Thiothixene tablets
C)Chlorpromazine IV injection
D)Aripiprazole IM injection

Answer 2

Thiothixene tablets

Question 3

MATCHING
Match the following generic drug names with their brand name.
a.Risperdal
b.Seroquel
c.Geodon
d.Loxitane
e.Clozaril
Loxapine

Answer 3

D

Question 4

Onset of schizophrenia typically occurs _____.

A)after age 45
B)before age 10
C)in the late teens
D)in the late 30s

Question 5

People diagnosed with schizophrenia often exhibit these types of symptoms except _____.

A)negative
B)positive
C)cognitive
D)neutral

Question 6

Why would a slow-release depot formulation be preferred when treating schizophrenia?

A)Eliminates the side effects associated with schizophrenia
B)Does not interfere with the metabolism of other drugs
C)Allows for once-a-day dosing because of its slow-release formulation
D)To allow for infrequent administration of the medication for maintenance therapy

Question 7

Which of the following is a side effect due to histaminergic (H₁)blockade caused by neuroleptic treatment?

A)Sedation
B)Weight loss
C)Urinary retention
D)Postural hypotension

Question 8

MATCHING
Match the following generic drug names with their brand name.
a.Risperdal
b.Seroquel
c.Geodon
d.Loxitane
e.Clozaril
Quetiapine

Question 9

MATCHING
Match the following generic drug names with their brand name.
a.Risperdal
b.Seroquel
c.Geodon
d.Loxitane
e.Clozaril
Clozapine

Question 10

Which of the following is not used in the treatment and management of schizophrenia and bipolar disorder?

A)Thienobenzodiazepines
B)Tranylcypromine
C)Risperidone
D)Quetiapine

Question 11

MATCHING
Match the following generic drug names with their brand name.
a.Risperdal
b.Seroquel
c.Geodon
d.Loxitane
e.Clozaril
Risperidone

Question 12

Which of the following should be labeled with a black box warning because use in elderly patients with dementia-related psychosis may increase risk of death?

A)Donepezil
B)Rivastigmine
C)Lurasidone
D)Galantamine

Question 13

_____ is the most significant neurotransmitter target when treating schizophrenia.

A)GABA
B)5-HT
C)Glutamate
D)DA

Question 14

Antagonizing which receptors is useful in the treatment of negative symptoms of schizophrenia?

A)DA
B)Glutamate
C)5-HT
D)Neurotensin

Question 15

What neurotransmitter is not associated with schizophrenia?

A)Acetylcholine
B)Glutamate
C)Cholecystokinin
D)Serotonin (5-hydroxytryptamine [5-HT])

Question 16

MATCHING
Match the following generic drug names with their brand name.
a.Risperdal
b.Seroquel
c.Geodon
d.Loxitane
e.Clozaril
Ziprasidone

Question 17

____ is classified as the prototype for low-potency neuroleptics.

A)Promethazine
B)Perphenazine
C)Chlorpromazine
D)Compazine

Question 18

Which of the following is thought to influence the development of schizophrenia?

A)Parkinson's disease
B)Drug abuse
C)Dementia
D)Bipolar disorder

Question 19

_____ is a side effect unique to the blockade of DA in the treatment of schizophrenia.

A)Dizziness
B)Lip smacking
C)Loss of appetite
D)Fatigue

Question 20

Traditional neuroleptics are well absorbed by the following dosage forms except:

A)tablets.
B)ODT tablets.
C)liquid for intramuscular (IM)injection.
D)creams.

Question 21

Schizophrenia does not run in families.

Question 22

Not all neuroleptic agents bind to dopamine (DA)receptors.

Question 23

Neuroleptic malignant syndrome (NMS)is a life-threatening side effect of neuroleptic administration.

Question 24

Traditional neuroleptics block DA at postsynaptic receptor sites.

Question 25

Persons diagnosed with schizophrenia often see visions or hear voices that cannot be seen or heard by others.