Deck 11: Neural Tissue
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Deck 11: Neural Tissue
1
Neurotransmitter for release is stored in synaptic
A) telodendria.
B) knobs.
C) vesicles.
D) mitochondria.
E) neurosomes.
A) telodendria.
B) knobs.
C) vesicles.
D) mitochondria.
E) neurosomes.
C
2
The cytoskeleton of the perikaryon contains which of the following?
A) neurofilaments
B) telodendria
C) neurotubules
D) all of the above
E) none of the above
A) neurofilaments
B) telodendria
C) neurotubules
D) all of the above
E) none of the above
D
3
Which of the following is not a function of the nervous system?
A) sense the internal and external environments
B) integrate sensory information
C) coordinate voluntary and involuntary activities
D) direct long-term functions, such as growth
E) control peripheral effectors
A) sense the internal and external environments
B) integrate sensory information
C) coordinate voluntary and involuntary activities
D) direct long-term functions, such as growth
E) control peripheral effectors
D
4
Axons terminate in a series of fine extensions known as
A) telodendria.
B) knobs.
C) collaterals.
D) dendrites.
E) synapses.
A) telodendria.
B) knobs.
C) collaterals.
D) dendrites.
E) synapses.
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5

Figure 11-1 The Neuron
Use Figure 11-1 to answer the following questions:
Which part of the neuron can conduct an action potential?
A) 1
B) 1 and 2
C) 2 and 3
D) 3 and 4
E) 3, 4, and 5
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6

Figure 11-1 The Neuron
Use Figure 11-1 to answer the following questions:
The structure labeled "2" is a
A) cell body.
B) dendrite.
C) axon hillock.
D) dendrite.
E) Nissl body.
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7
The ________ nervous system is composed of the brain and spinal cord.
A) autonomic
B) peripheral
C) central
D) efferent
E) afferent
A) autonomic
B) peripheral
C) central
D) efferent
E) afferent
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8

Figure 11-1 The Neuron
Use Figure 11-1 to answer the following questions:
Identify the structure labeled "5."
A) axons
B) telodendria
C) dendritic spines
D) synaptic terminals
E) axosomata
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9
The cytoplasm that surrounds the nucleus of a neuron is called the
A) protoplasm.
B) nucleoplasm.
C) sarcoplasm.
D) neuroplasm.
E) perikaryon.
A) protoplasm.
B) nucleoplasm.
C) sarcoplasm.
D) neuroplasm.
E) perikaryon.
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10
Most CNS neurons lack centrioles. This observation explains
A) why CNS neurons grow such long axons.
B) why CNS neurons cannot regenerate.
C) the ability of neurons to generate an action potential.
D) the ability of neurons to communicate with each other.
E) the ability of neurons to produce a resting potential.
A) why CNS neurons grow such long axons.
B) why CNS neurons cannot regenerate.
C) the ability of neurons to generate an action potential.
D) the ability of neurons to communicate with each other.
E) the ability of neurons to produce a resting potential.
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11
Which of the following is not a recognized structural classification for neurons?
A) anaxonic
B) bipolar
C) multipolar
D) pseudopolar
E) unipolar
A) anaxonic
B) bipolar
C) multipolar
D) pseudopolar
E) unipolar
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12
The most abundant class of neuron in the central nervous system is
A) anaxonic.
B) bipolar.
C) multipolar.
D) pseudopolar.
E) unipolar.
A) anaxonic.
B) bipolar.
C) multipolar.
D) pseudopolar.
E) unipolar.
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13
Clusters of RER and free ribosomes in neurons are called
A) neurofilaments.
B) neurofibrils.
C) perikaryon.
D) Nissl bodies.
E) microglia.
A) neurofilaments.
B) neurofibrils.
C) perikaryon.
D) Nissl bodies.
E) microglia.
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14
The ________ nervous system controls the skeletal muscles.
A) sympathetic
B) parasympathetic
C) afferent
D) somatic
E) autonomic
A) sympathetic
B) parasympathetic
C) afferent
D) somatic
E) autonomic
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15
Branches that may occur along an axon are called
A) dendrites.
B) synaptic knobs.
C) collaterals.
D) hillocks.
E) synapses.
A) dendrites.
B) synaptic knobs.
C) collaterals.
D) hillocks.
E) synapses.
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16
The site of intercellular communication between neurons is the
A) telodendria.
B) synaptic knob.
C) collateral.
D) hillock.
E) synapse.
A) telodendria.
B) synaptic knob.
C) collateral.
D) hillock.
E) synapse.
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17

Figure 11-1 The Neuron
Use Figure 11-1 to answer the following questions:
Which type of membrane channels are found at label "3"?
A) voltage-gated Na⁺ channels
B) voltage-gated K⁺ channels
C) chemically gated Na⁺ and K⁺ channels
D) voltage-gated Ca²⁺ channels
E) voltage-gated Na⁺ and K⁺ channels
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18
The axoplasm of the axon contains which of the following?
A) neurotubules
B) mitochondria
C) vesicles
D) neurofibrils
E) all of the above
A) neurotubules
B) mitochondria
C) vesicles
D) neurofibrils
E) all of the above
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19
The axon is connected to the cell body at the
A) telodendria.
B) synaptic knobs.
C) collaterals.
D) axon hillock.
E) synapse.
A) telodendria.
B) synaptic knobs.
C) collaterals.
D) axon hillock.
E) synapse.
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20

Figure 11-1 The Neuron
Use Figure 11-1 to answer the following questions:
The structures labeled "1" are dendrites. Their membranes contain numerous chemically gated ion channels.
A) The first statement is True but the second statement is False
)
B) The first statement is False but the second statement is True
)
C) Both statements are True .
D) Both statements are False .
E) Both statements are True and relate to synaptic transmission.
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21
________ account for roughly half of the volume of the nervous system.
A) Axons
B) Dendrites
C) Neuroglia
D) Synapses
E) Efferent fibers
A) Axons
B) Dendrites
C) Neuroglia
D) Synapses
E) Efferent fibers
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22
________ are the most numerous type of neuron in the CNS.
A) Sensory neurons
B) Motor neurons
C) Unipolar neurons
D) Bipolar neurons
E) Interneurons
A) Sensory neurons
B) Motor neurons
C) Unipolar neurons
D) Bipolar neurons
E) Interneurons
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23
________ line the brain ventricles and spinal canal.
A) Astrocytes
B) Satellite cells
C) Oligodendrocytes
D) Microglia
E) Ependymal cells
A) Astrocytes
B) Satellite cells
C) Oligodendrocytes
D) Microglia
E) Ependymal cells
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24
Small, wandering cells that engulf cell debris and pathogens in the CNS are called
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) ependymal cells.
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) ependymal cells.
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25
The glial cells in the central nervous system that form scar tissue after Central Nervous System injury are the
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) ependymal cells.
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) ependymal cells.
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26
________ neurons are short, with a cell body between dendrite and axon, and occur in special sense organs.
A) Multipolar
B) Anaxonic
C) Unipolar
D) Bipolar
E) none of the above
A) Multipolar
B) Anaxonic
C) Unipolar
D) Bipolar
E) none of the above
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27
Which of the following is not a function of the neuroglia?
A) support
B) memory
C) secretion of cerebrospinal fluid
D) maintenance of blood-brain barrier
E) phagocytosis
A) support
B) memory
C) secretion of cerebrospinal fluid
D) maintenance of blood-brain barrier
E) phagocytosis
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28
Neurons that have one axon and one dendrite, with the soma in between, are called
A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.
A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.
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29
The myelin sheath that covers many CNS axons is formed by
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) ependymal cells.
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) ependymal cells.
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30
________ neurons are small and have no anatomical features that distinguish dendrites from axons.
A) Multipolar
B) Anaxonic
C) Unipolar
D) Bipolar
E) none of the above
A) Multipolar
B) Anaxonic
C) Unipolar
D) Bipolar
E) none of the above
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31
Sensory neurons of the PNS are
A) unipolar.
B) bipolar.
C) anaxonic.
D) multipolar.
E) tripolar.
A) unipolar.
B) bipolar.
C) anaxonic.
D) multipolar.
E) tripolar.
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32
Which of the following is a function of neuroglia?
A) regulate the composition of interstitial fluid
B) provide a supportive framework
C) produce cerebrospinal fluid
D) act as phagocytes
E) all of the above
A) regulate the composition of interstitial fluid
B) provide a supportive framework
C) produce cerebrospinal fluid
D) act as phagocytes
E) all of the above
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33
________ neurons are the most common class in the CNS.
A) Multipolar
B) Anaxonic
C) Unipolar
D) Bipolar
E) none of the above
A) Multipolar
B) Anaxonic
C) Unipolar
D) Bipolar
E) none of the above
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34
Which of the following are types of neuroglia?
A) ependymal cells
B) microglia
C) astrocytes
D) oligodendrocytes
E) all of the above
A) ependymal cells
B) microglia
C) astrocytes
D) oligodendrocytes
E) all of the above
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35
Which of the following activities or sensations is not monitored by interoceptors?
A) sight
B) taste
C) activities of the digestive system
D) cardiovascular activities
E) urinary activities
A) sight
B) taste
C) activities of the digestive system
D) cardiovascular activities
E) urinary activities
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36
Neurons that have several dendrites and a single axon are called
A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.
A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.
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37
In a(n) ________ neuron, the dendrites and axon are continuous or fused.
A) multipolar
B) anaxonic
C) unipolar
D) bipolar
E) none of the above
A) multipolar
B) anaxonic
C) unipolar
D) bipolar
E) none of the above
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38
Neurons in which dendritic and axonal processes are continuous and the soma lies off to one side are called
A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.
A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.
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39
Neurons that are rare, small, and lack features that distinguish dendrites from axons are called
A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.
A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.
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40
Functions of astrocytes include all of the following, except
A) maintaining the blood-brain barrier.
B) conducting action potentials.
C) guiding neuron development.
D) responding to neural tissue damage.
E) forming a three-dimensional framework for the CNS.
A) maintaining the blood-brain barrier.
B) conducting action potentials.
C) guiding neuron development.
D) responding to neural tissue damage.
E) forming a three-dimensional framework for the CNS.
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41
If the sodium-potassium pumps in the plasma membrane fail to function, all of the following occur, except
A) the intracellular concentration of potassium ions will increase.
B) the neuron will slowly depolarize.
C) the membrane will slowly lose its capacity to generate action potentials.
D) the inside of the membrane will have a resting potential that is more positive than normal.
E) the intracellular concentration of sodium ions will increase.
A) the intracellular concentration of potassium ions will increase.
B) the neuron will slowly depolarize.
C) the membrane will slowly lose its capacity to generate action potentials.
D) the inside of the membrane will have a resting potential that is more positive than normal.
E) the intracellular concentration of sodium ions will increase.
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42
The largest and most numerous neuroglia in the CNS that absorb and recycle neurotransmitters are the
A) astrocytes.
B) ependymal cells.
C) microglia.
D) oligodendrocytes.
E) none of the above
A) astrocytes.
B) ependymal cells.
C) microglia.
D) oligodendrocytes.
E) none of the above
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43
The smallest neuroglia of the CNS that act as phagocytes are the
A) astrocytes.
B) ependymal cells.
C) microglia.
D) oligodendrocytes.
E) none of the above
A) astrocytes.
B) ependymal cells.
C) microglia.
D) oligodendrocytes.
E) none of the above
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44
In the peripheral nervous system, Schwann cells participate in the repair of damaged nerves by
A) producing new axons.
B) regenerating cell bodies for the neurons.
C) forming a cellular cord that directs axonal regrowth.
D) clearing away cellular debris.
E) producing more satellite cells that fuse to form new axons.
A) producing new axons.
B) regenerating cell bodies for the neurons.
C) forming a cellular cord that directs axonal regrowth.
D) clearing away cellular debris.
E) producing more satellite cells that fuse to form new axons.
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45
Voltage-gated channels are present
A) at the motor end plate.
B) on the surface of dendrites.
C) in the membrane that covers axons.
D) on the soma of neurons.
E) along the perikaryon of neurons.
A) at the motor end plate.
B) on the surface of dendrites.
C) in the membrane that covers axons.
D) on the soma of neurons.
E) along the perikaryon of neurons.
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46
At the normal resting potential of a typical neuron, its Na-K ion exchange pump transports
A) 1 intracellular sodium ion for 2 extracellular potassium ions.
B) 2 intracellular sodium ions for 1 extracellular potassium ion.
C) 3 intracellular sodium ions for 1 extracellular potassium ion.
D) 3 intracellular sodium ions for 2 extracellular potassium ions.
E) 3 extracellular sodium ions for 2 intracellular potassium ions.
A) 1 intracellular sodium ion for 2 extracellular potassium ions.
B) 2 intracellular sodium ions for 1 extracellular potassium ion.
C) 3 intracellular sodium ions for 1 extracellular potassium ion.
D) 3 intracellular sodium ions for 2 extracellular potassium ions.
E) 3 extracellular sodium ions for 2 intracellular potassium ions.
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47
After a stroke, what type of glial cell accumulates within the affected brain region?
A) Schwann cells
B) satellite cells
C) oligodendrocytes
D) microglia
E) ependymal cells
A) Schwann cells
B) satellite cells
C) oligodendrocytes
D) microglia
E) ependymal cells
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48
Ion channels that are always open are called ________ channels.
A) active
B) gated
C) leak
D) regulated
E) local
A) active
B) gated
C) leak
D) regulated
E) local
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49
The equilibrium potential for potassium ion occurs at approximately
A) -90 mV.
B) -70 mV.
C) +66 mV.
D) 0 mV.
E) -55 mV.
A) -90 mV.
B) -70 mV.
C) +66 mV.
D) 0 mV.
E) -55 mV.
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50
Extensive damage to oligodendrocytes in the CNS could result in
A) loss of the structural framework of the brain.
B) a breakdown of the blood-brain barrier.
C) inability to produce scar tissue at the site of an injury.
D) decreased production of cerebrospinal fluid.
E) loss of sensation and motor control.
A) loss of the structural framework of the brain.
B) a breakdown of the blood-brain barrier.
C) inability to produce scar tissue at the site of an injury.
D) decreased production of cerebrospinal fluid.
E) loss of sensation and motor control.
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51
Which of the following is a type of glial cell found in the peripheral nervous system?
A) astrocytes
B) satellite cells
C) oligodendrocytes
D) microglia
E) ependymal cells
A) astrocytes
B) satellite cells
C) oligodendrocytes
D) microglia
E) ependymal cells
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52
The function of the astrocytes in the CNS includes which of the following?
A) adjusting the composition of the interstitial fluid
B) providing structural support within neural tissue
C) maintaining the blood-brain barrier
D) repairing damaged neural tissue
E) all of the above
A) adjusting the composition of the interstitial fluid
B) providing structural support within neural tissue
C) maintaining the blood-brain barrier
D) repairing damaged neural tissue
E) all of the above
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53
Which of the following interactions between electrical and chemical gradients does not lead to the establishment of a neuron's resting potential?
A) Chemical and electrical forces both favor sodium ions entering the cell.
B) Electrical forces push sodium ions out of the cell.
C) Chemical forces tend to drive potassium ions out of the cell.
D) Potassium ions are attracted to the negative charges inside the cell.
E) Potassium ions are repulsed by positive charges outside the cell.
A) Chemical and electrical forces both favor sodium ions entering the cell.
B) Electrical forces push sodium ions out of the cell.
C) Chemical forces tend to drive potassium ions out of the cell.
D) Potassium ions are attracted to the negative charges inside the cell.
E) Potassium ions are repulsed by positive charges outside the cell.
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54
Damage to ependymal cells would most likely affect the
A) formation of myelin sheaths.
B) formation of cerebrospinal fluid.
C) formation of ganglia.
D) repair of axons.
E) transport of neurotransmitters within axons.
A) formation of myelin sheaths.
B) formation of cerebrospinal fluid.
C) formation of ganglia.
D) repair of axons.
E) transport of neurotransmitters within axons.
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55
The neurilemma of axons in the peripheral nervous system is formed by
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) Schwann cells.
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) Schwann cells.
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56
Raising the potassium ion concentration in the extracellular fluid surrounding a nerve cell will have which effect?
A) depolarize it
B) hyperpolarize it
C) increase the magnitude of the potassium equilibrium potential
D) decrease the magnitude of the sodium equilibrium potential
E) increase the magnitude of the sodium equilibrium potential
A) depolarize it
B) hyperpolarize it
C) increase the magnitude of the potassium equilibrium potential
D) decrease the magnitude of the sodium equilibrium potential
E) increase the magnitude of the sodium equilibrium potential
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57
Glial cells that surround the neurons in ganglia are
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) ependymal cells.
A) astrocytes.
B) satellite cells.
C) oligodendrocytes.
D) microglia.
E) ependymal cells.
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58
Deteriorating changes in the distal segment of an axon as a result of a break between it and the soma is called ________ degeneration.
A) neural
B) central
C) peripheral
D) Wallerian
E) conduction
A) neural
B) central
C) peripheral
D) Wallerian
E) conduction
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59
Many medications introduced into the bloodstream cannot directly affect the neurons of the CNS because
A) oligodendrocytes form a continuous myelin sheath around the axons.
B) the astrocytes isolate the CNS by forming a blood-brain barrier.
C) the neurilemma is impermeable to most molecules.
D) ependymal cells restrict the flow of interstitial fluid between the capillaries and the neurons.
E) Schwann cells form a capsule around neurons.
A) oligodendrocytes form a continuous myelin sheath around the axons.
B) the astrocytes isolate the CNS by forming a blood-brain barrier.
C) the neurilemma is impermeable to most molecules.
D) ependymal cells restrict the flow of interstitial fluid between the capillaries and the neurons.
E) Schwann cells form a capsule around neurons.
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60
Ion channels that are always open are known as
A) leak channels.
B) active channels.
C) chemically gated channels.
D) voltage-gated channels.
E) mechanically-gated channels.
A) leak channels.
B) active channels.
C) chemically gated channels.
D) voltage-gated channels.
E) mechanically-gated channels.
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61
If the potassium permeability of a resting neuron increases above the resting permeability, what effect will this have on the transmembrane potential?
A) The inside of the membrane will become more positive.
B) The inside of the membrane will become more negative.
C) There will be almost no effect on transmembrane potential.
D) The membrane will become depolarized.
E) none of the above
A) The inside of the membrane will become more positive.
B) The inside of the membrane will become more negative.
C) There will be almost no effect on transmembrane potential.
D) The membrane will become depolarized.
E) none of the above
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62
Which of the following is not involved in creating the resting potential of a neuron?
A) diffusion of potassium ions out of the cell
B) diffusion of sodium ions into the cell
C) Membrane permeability for sodium ions is greater than for potassium ions.
D) Membrane permeability for potassium ions is greater than for sodium ions.
E) The interior of the plasma membrane has an excess of negative charges.
A) diffusion of potassium ions out of the cell
B) diffusion of sodium ions into the cell
C) Membrane permeability for sodium ions is greater than for potassium ions.
D) Membrane permeability for potassium ions is greater than for sodium ions.
E) The interior of the plasma membrane has an excess of negative charges.
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63
Opening of sodium channels in the axon membrane causes
A) depolarization.
B) repolarization.
C) hyperpolarization.
D) increased positive charge inside the membrane.
E) both depolarization and increased positive charge inside the membrane.
A) depolarization.
B) repolarization.
C) hyperpolarization.
D) increased positive charge inside the membrane.
E) both depolarization and increased positive charge inside the membrane.
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64
The sodium-potassium ion exchange pump
A) is not involved in producing the resting membrane potential.
B) transports sodium ions into the cell during depolarization.
C) transports potassium ions out of the cell during repolarization.
D) moves sodium and potassium opposite to the direction of their electrochemical gradients.
E) depends on a hydrogen gradient for energy.
A) is not involved in producing the resting membrane potential.
B) transports sodium ions into the cell during depolarization.
C) transports potassium ions out of the cell during repolarization.
D) moves sodium and potassium opposite to the direction of their electrochemical gradients.
E) depends on a hydrogen gradient for energy.
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65
Ions can move across the plasma membrane in which of the following ways?
A) through voltage-gated channels as in the action potential
B) through passive or leak channels
C) by ATP-dependent ion pumps like the sodium-potassium exchange pump
D) through chemically-gated channels as in neuromuscular transmission
E) all of the above
A) through voltage-gated channels as in the action potential
B) through passive or leak channels
C) by ATP-dependent ion pumps like the sodium-potassium exchange pump
D) through chemically-gated channels as in neuromuscular transmission
E) all of the above
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66

Figure 11-2 The Nerve Action Potential
Use Figure 11-2 to answer the following questions:
Which area of the graph occurs when there is a sudden inrush of sodium ions?
A) 1
B) 2
C) 3
D) 4
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67

Figure 11-2 The Nerve Action Potential
Use Figure 11-2 to answer the following questions:
When is the neuron in the refractory period?
A) 1
B) 2
C) 3
D) 4
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68

Figure 11-2 The Nerve Action Potential
Use Figure 11-2 to answer the following questions:
Which area of the graph shows when passive depolarization is occurring?
A) 1
B) 2
C) 3
D) 4
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69
If the permeability of a resting axon to sodium ion increases,
A) the membrane potential will depolarize.
B) the membrane potential will hyperpolarize.
C) inward movement of sodium ions will increase.
D) outward movement of sodium ions will decrease.
E) both the inward movement of sodium ions will increase and the membrane potential will depolarize.
A) the membrane potential will depolarize.
B) the membrane potential will hyperpolarize.
C) inward movement of sodium ions will increase.
D) outward movement of sodium ions will decrease.
E) both the inward movement of sodium ions will increase and the membrane potential will depolarize.
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70
________ channels open or close in response to physical distortion of the membrane surface.
A) Voltage-gated
B) Chemically gated
C) Active
D) Mechanically gated
E) Leak
A) Voltage-gated
B) Chemically gated
C) Active
D) Mechanically gated
E) Leak
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71
The all-or-none principle states that
A) all stimuli will produce identical action potentials.
B) all stimuli great enough to bring the membrane to threshold will produce identical action potentials.
C) the greater the magnitude of the stimuli, the greater the magnitude of the action potential.
D) only sensory stimuli can activate action potentials.
E) only motor stimuli can activate action potentials.
A) all stimuli will produce identical action potentials.
B) all stimuli great enough to bring the membrane to threshold will produce identical action potentials.
C) the greater the magnitude of the stimuli, the greater the magnitude of the action potential.
D) only sensory stimuli can activate action potentials.
E) only motor stimuli can activate action potentials.
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72
Graded potentials
A) produce an effect that increases with distance from the point of stimulation.
B) produce an effect that spreads actively across the membrane surface without diminishing.
C) may be either a depolarization or a hyperpolarization.
D) are often all-or-none.
E) always cause repolarization.
A) produce an effect that increases with distance from the point of stimulation.
B) produce an effect that spreads actively across the membrane surface without diminishing.
C) may be either a depolarization or a hyperpolarization.
D) are often all-or-none.
E) always cause repolarization.
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73
The following are the main steps in the generation of an action potential.
1) Sodium channels are inactivated.
2) Voltage-gated potassium channels open and potassium moves out of the cell, initiating repolarization.
3) Sodium channels regain their normal properties.
4) A graded depolarization brings an area of an excitable membrane to threshold.
5) A temporary hyperpolarization occurs.
6) Sodium channel activation occurs.
7) Sodium ions enter the cell and depolarization occurs.
The proper sequence of these events is
A) 4, 6, 7, 3, 2, 5, 1.
B) 4, 6, 7, 1, 2, 3, 5.
C) 6, 7, 4, 1, 2, 3, 5.
D) 2, 4, 6, 7, 1, 3, 5.
E) 4, 2, 5, 6, 7, 3, 1.
1) Sodium channels are inactivated.
2) Voltage-gated potassium channels open and potassium moves out of the cell, initiating repolarization.
3) Sodium channels regain their normal properties.
4) A graded depolarization brings an area of an excitable membrane to threshold.
5) A temporary hyperpolarization occurs.
6) Sodium channel activation occurs.
7) Sodium ions enter the cell and depolarization occurs.
The proper sequence of these events is
A) 4, 6, 7, 3, 2, 5, 1.
B) 4, 6, 7, 1, 2, 3, 5.
C) 6, 7, 4, 1, 2, 3, 5.
D) 2, 4, 6, 7, 1, 3, 5.
E) 4, 2, 5, 6, 7, 3, 1.
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74
________ open or close in response to binding specific molecules.
A) Leak channels
B) Activated channels
C) Chemically gated channels
D) Voltage-gated channels
E) Mechanically-gated channels
A) Leak channels
B) Activated channels
C) Chemically gated channels
D) Voltage-gated channels
E) Mechanically-gated channels
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75
Any stimulus that opens ________ ion channel will produce a graded potential.
A) a voltage-gated
B) a chemically gated
C) a sodium
D) a mechanically gated
E) any of the above
A) a voltage-gated
B) a chemically gated
C) a sodium
D) a mechanically gated
E) any of the above
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76
Which of the following comparisons between neurons and muscle tissue is False ?
A) Resting potentials are greater in muscle fibers.
B) Muscle fibers conduct action potentials at slow speeds.
C) Action potentials last longer in muscle fibers.
D) Muscle fibers conduct action potentials only by continuous propagation.
E) Action potentials are briefer in muscle fibers.
A) Resting potentials are greater in muscle fibers.
B) Muscle fibers conduct action potentials at slow speeds.
C) Action potentials last longer in muscle fibers.
D) Muscle fibers conduct action potentials only by continuous propagation.
E) Action potentials are briefer in muscle fibers.
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77

Figure 11-2 The Nerve Action Potential
Use Figure 11-2 to answer the following questions:
Which point of the graph shows when potassium ion outflow exceeds sodium ion inflow?
A) 1
B) 2
C) 3
D) 4
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78
Puffer fish poison blocks voltage-gated sodium channels like a cork. What effect would this neurotoxin have on the function of neurons?
A) Neurons would depolarize more rapidly.
B) Action potentials would lack a repolarization phase.
C) The absolute refractory period would be shorter than normal.
D) The axon would be unable to generate action potentials.
E) None, because the chemically gated sodium channels would still function.
A) Neurons would depolarize more rapidly.
B) Action potentials would lack a repolarization phase.
C) The absolute refractory period would be shorter than normal.
D) The axon would be unable to generate action potentials.
E) None, because the chemically gated sodium channels would still function.
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79
Voltage-gated sodium channels have both an activation gate and a(n) ________ gate.
A) inactivation
B) ion
C) swinging
D) repolarization
E) threshold
A) inactivation
B) ion
C) swinging
D) repolarization
E) threshold
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80

Figure 11-2 The Nerve Action Potential
Use Figure 11-2 to answer the following questions:
Which area of the graph shows when membrane potential approaches the potassium equilibrium potential?
A) 1
B) 2
C) 3
D) 4
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