Deck 24: Diseases of the Nervous System
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Deck 24: Diseases of the Nervous System
1
The central nervous system includes all of the following except:
A)brain
B)spinal cord
C)nerves that reach the tissues in limbs
D)microglial cells
A)brain
B)spinal cord
C)nerves that reach the tissues in limbs
D)microglial cells
C
2
Polyomavirus particles can be observed in the _____ cells of the nervous system.
A)microglial
B)oligodendrocyte
C)sensory neuron
D)association neuron
A)microglial
B)oligodendrocyte
C)sensory neuron
D)association neuron
B
3
Waterhouse-Friderichsen syndrome is a complication of _____.
A)Fungal meningitis
B)Streptococcus meningitis
C)viral meningitis
D)meningococcal meningitis
A)Fungal meningitis
B)Streptococcus meningitis
C)viral meningitis
D)meningococcal meningitis
D
4
Hib vaccine is limited to:
A)Haemophilus meningitis
B)Haemophilus encephalitis
C)the number of cases of mental retardation
D)two of these choices
A)Haemophilus meningitis
B)Haemophilus encephalitis
C)the number of cases of mental retardation
D)two of these choices
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5
________ can be especially dangerous to pregnant women causing abortion,stillbirth,or neonatal death.
A)Meningococcal meningitis
B)Listeriosis
C)Streptococcal meningitis
D)Haemophilus meningitis
A)Meningococcal meningitis
B)Listeriosis
C)Streptococcal meningitis
D)Haemophilus meningitis
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6
Which term refers to aggregates of neuron cell bodies in the peripheral nervous system?
A)ganglia
B)microglial cells
C)blood-brain barrier
D)meninges
A)ganglia
B)microglial cells
C)blood-brain barrier
D)meninges
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7
Acute meningitis is consistent with all of the following except:
A)organisms could be endogenous
B)organisms can spread from pneumonia
C)symptoms are insidious, occurring over a period of weeks
D)organisms spread from otitis media
A)organisms could be endogenous
B)organisms can spread from pneumonia
C)symptoms are insidious, occurring over a period of weeks
D)organisms spread from otitis media
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8
Treatment for tubercular meningitis includes:
A)isoniazid
B)penicillin
C)tetracycline
D)amphotericin B
A)isoniazid
B)penicillin
C)tetracycline
D)amphotericin B
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9
Which of the following viral encephalitis infections is not caused by a togavirus?
A)Eastern equine encephalitis
B)St. Louis encephalitis
C)Western equine encephalitis
D)Venezuelan equine encephalitis
A)Eastern equine encephalitis
B)St. Louis encephalitis
C)Western equine encephalitis
D)Venezuelan equine encephalitis
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10
A foodborne pathogen that can cause meningitis is _____.
A)Streptococcus pneumoniae
B)Staphylococcus epidermidis
C)Listeria monocytogenes
D)Neisseria meningitidis
A)Streptococcus pneumoniae
B)Staphylococcus epidermidis
C)Listeria monocytogenes
D)Neisseria meningitidis
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11
Herpes meningoencephalitis usually follows _____.
A)a bacterial infection of the respiratory tract
B)a generalized herpes infection
C)a fever blister outbreak
D)an outbreak of genital herpes
A)a bacterial infection of the respiratory tract
B)a generalized herpes infection
C)a fever blister outbreak
D)an outbreak of genital herpes
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12
The most common domestic rabid animals in the United States today are _____.
A)dogs
B)ferrets
C)cats
D)bats
A)dogs
B)ferrets
C)cats
D)bats
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13
Acanthamoeba polyphaga can accumulate on the surface of water in hot tubs. Upon infection,they cause:
A)eye ulcerations
B)skin ulcerations
C)meningoencephalitis
D)all of these choices
A)eye ulcerations
B)skin ulcerations
C)meningoencephalitis
D)all of these choices
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14
Which of the following terms refers to special thick-walled capillaries without pores in their walls?
A)ganglia
B)meninges
C)blood-brain barrier
D)two of these choices
A)ganglia
B)meninges
C)blood-brain barrier
D)two of these choices
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15
All of the following statements about rabies are true except:
A)to transmit the virus, the animal must be shedding the virus in the saliva.
B)rabies progresses rapidly to the brain by the flow of cytoplasm through axons.
C)incubation time is proportional to the distance between the bite wound and the brain.
D)symptoms include hydrophobia, aerophobia, confusion, and hallucination.
A)to transmit the virus, the animal must be shedding the virus in the saliva.
B)rabies progresses rapidly to the brain by the flow of cytoplasm through axons.
C)incubation time is proportional to the distance between the bite wound and the brain.
D)symptoms include hydrophobia, aerophobia, confusion, and hallucination.
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16
The most common cause of meningitis in adults is:
A)Neisseria meningitidis
B)Haemophilus influenzae type B
C)Streptococcus pneumoniae
D)Listeria monocytogenes
A)Neisseria meningitidis
B)Haemophilus influenzae type B
C)Streptococcus pneumoniae
D)Listeria monocytogenes
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17
Which of the following is a cellular component of the immune system that protects the brain?
A)ganglia
B)microglial cells
C)blood-brain barrier
D)meninges
A)ganglia
B)microglial cells
C)blood-brain barrier
D)meninges
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18
The most sensitive method for detecting rabies is _____.
A)finding Negri bodies in brain cells
B)finding anti-rabies antibodies in the serum
C)finding the symptoms of disease
D)immunofluorescent antibody test
A)finding Negri bodies in brain cells
B)finding anti-rabies antibodies in the serum
C)finding the symptoms of disease
D)immunofluorescent antibody test
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19
While over 90% of populations that live in closed environments (such as military bases,dormitories and day-care centers are carriers)only 1 of 1000 carriers will have meningitis. This statement refers to _____.
A)Neisseria meningitidis
B)Haemophilus influenzae type B
C)Streptococcus pneumoniae
D)Haemophilus influenzae type F
A)Neisseria meningitidis
B)Haemophilus influenzae type B
C)Streptococcus pneumoniae
D)Haemophilus influenzae type F
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20
Which of the following is not a viral or bacterial cause of meningitis?
A)Naegleria fowleri
B)Haemophilus influenzae type F
C)Treponema pallidum
D)Mycobacterium tuberculosis
A)Naegleria fowleri
B)Haemophilus influenzae type F
C)Treponema pallidum
D)Mycobacterium tuberculosis
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21
Clostridium botulinum is characterized by all of the following except:
A)preformed toxin in food prevents release of acetylcholine
B)progressive multifocal leukoencephalopathy
C)paralysis and death results if not treated promptly
D)in wounds endospores germinate and produce toxin
A)preformed toxin in food prevents release of acetylcholine
B)progressive multifocal leukoencephalopathy
C)paralysis and death results if not treated promptly
D)in wounds endospores germinate and produce toxin
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22
Tetanus neonatorum is:
A)due to tetanus acquired through the birth canal
B)an infection of the umbilical cord
C)a muscle spasm that has nothing to do with Clostridium
D)an infection from Clostridium in contaminated breast milk
A)due to tetanus acquired through the birth canal
B)an infection of the umbilical cord
C)a muscle spasm that has nothing to do with Clostridium
D)an infection from Clostridium in contaminated breast milk
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23
All of the following statements about the nodular form of Hansen's disease are true EXCEPT:
A)incubation time averages 2 - 5 years
B)the bacteria has a predilection for cooler parts of the human body.
C)severe lepromatous disease erodes bone
D)surgery can restore the use of extremely crippled hands and feet
A)incubation time averages 2 - 5 years
B)the bacteria has a predilection for cooler parts of the human body.
C)severe lepromatous disease erodes bone
D)surgery can restore the use of extremely crippled hands and feet
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24
One problem with treating Hansen's disease is _____.
A)antibiotics are not effective against the Mycobacterium
B)dapsone-resistant strains are beginning to appear
C)the organism is growing too rapidly for the antibiotic to work
D)the bacteria survive inside the microglial cells
A)antibiotics are not effective against the Mycobacterium
B)dapsone-resistant strains are beginning to appear
C)the organism is growing too rapidly for the antibiotic to work
D)the bacteria survive inside the microglial cells
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25
Health care workers should watch for undiagnosed Hansen's disease among _____.
A)farmers
B)urban dwellers
C)veterinarians
D)immigrants
A)farmers
B)urban dwellers
C)veterinarians
D)immigrants
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26
Mycobacterium leprae is difficult to cultivate but it can be grown _____.
A)on blood agar
B)in armadillos
C)in tissue culture
D)in embryonated eggs
A)on blood agar
B)in armadillos
C)in tissue culture
D)in embryonated eggs
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27
Tetanus is treated by _____.
A)antibiotic therapy
B)antiviral therapy
C)antitoxin therapy
D)two of these choices
A)antibiotic therapy
B)antiviral therapy
C)antitoxin therapy
D)two of these choices
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28
Which of the following refers to the clinical form of leprosy that causes a loss of skin pigment and sensation?
A)granulomatous
B)lepromatous
C)tuberculoid
D)two of these choices
A)granulomatous
B)lepromatous
C)tuberculoid
D)two of these choices
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29
Hansen's disease is diagnosed by _____.
A)PCR
B)finding antibodies in the serum
C)lepromin skin test
D)two of these choices
A)PCR
B)finding antibodies in the serum
C)lepromin skin test
D)two of these choices
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30
Clostridium tetani can be characterized by all of the following except:
A)Gram-positive spore former
B)resistant to drying, disinfection, and heat
C)endospores are killed by boiling for 20 minutes
D)common to soil and human intestines
A)Gram-positive spore former
B)resistant to drying, disinfection, and heat
C)endospores are killed by boiling for 20 minutes
D)common to soil and human intestines
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31
_______ is the only bacterial species known to destroy peripheral nerve cells.
A)Staphylococcus aureus
B)Herpes simplex I
C)Clostridium tetani
D)Mycobacterium leprae
A)Staphylococcus aureus
B)Herpes simplex I
C)Clostridium tetani
D)Mycobacterium leprae
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32
Which of the following is responsible for Chagas' disease?
A)Mycobacterium leprae
B)Clostridium tetani
C)Trypanosoma cruzi
D)Poliovirus
A)Mycobacterium leprae
B)Clostridium tetani
C)Trypanosoma cruzi
D)Poliovirus
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33
All of the following are symptoms of poliovirus except:
A)muscle spasms
B)heart damage
C)partial or complete flaccid paralysis
D)destruction of motor neurons
A)muscle spasms
B)heart damage
C)partial or complete flaccid paralysis
D)destruction of motor neurons
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34
Humans are naturally protected against nagana,a tsetse-fly-bourne cattle disease. What has been found to serve the protective role?
A)Serum
B)High-density lipoprotein (HDL)
C)Low-density lipoprotein (LDL)
D)Iron
A)Serum
B)High-density lipoprotein (HDL)
C)Low-density lipoprotein (LDL)
D)Iron
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35
Botulism includes _____.
A)food poisoning
B)infant botulism
C)wound botulism
D)all of these choices
A)food poisoning
B)infant botulism
C)wound botulism
D)all of these choices
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36
African sleeping sickness is caused by _____.
A)Trypanosoma brucei gambiense
B)Yersinia pestis
C)Trypanosoma cruzi
D)prions
A)Trypanosoma brucei gambiense
B)Yersinia pestis
C)Trypanosoma cruzi
D)prions
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37
All of the following are associated with prions except:
A)Chagas' disease
B)Kuru
C)Scrapie
D)Mad cow disease
A)Chagas' disease
B)Kuru
C)Scrapie
D)Mad cow disease
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38
All of the following statements refer to mad cow disease except
A)it is caused by an infectious protein
B)its transmission to humans can be prevented by banning the addition of beef brain tissue to hamburger
C)it only occurs in Britain
D)it causes disease in both humans and animals
A)it is caused by an infectious protein
B)its transmission to humans can be prevented by banning the addition of beef brain tissue to hamburger
C)it only occurs in Britain
D)it causes disease in both humans and animals
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39
Botulism toxin is characterized by all of the following except:
A)most potent toxin known
B)released upon autolysis of cells
C)boiling will not inactivate the toxin
D)activated by proteolytic enzymes
A)most potent toxin known
B)released upon autolysis of cells
C)boiling will not inactivate the toxin
D)activated by proteolytic enzymes
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40
Tetanus is most common in _____.
A)newborns
B)adolescents
C)young adult athletes
D)older women
A)newborns
B)adolescents
C)young adult athletes
D)older women
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41
Which of the following statements is incorrect about JC virus?
A)Antibodies are seen by age 14.
B)Disease may be a reactivation of a latent viral infection.
C)Leads to flaccid paralysis of respiratory muscles.
D)JC is responsible for progressive multifocal leukoencephalopathy.
A)Antibodies are seen by age 14.
B)Disease may be a reactivation of a latent viral infection.
C)Leads to flaccid paralysis of respiratory muscles.
D)JC is responsible for progressive multifocal leukoencephalopathy.
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42
This organism can exist in the spore form and cause tetanus. 
A)Mycobacterium leprae
B)Clostridium tetani
C)Clostridium difficile
D)Clostridium botulinum

A)Mycobacterium leprae
B)Clostridium tetani
C)Clostridium difficile
D)Clostridium botulinum
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43
Which of the following is an emerging viral encephalitis that has recently spread across the United States?
A)JC virus
B)rabies
C)mad cow disease
D)West Nile arbovirus
A)JC virus
B)rabies
C)mad cow disease
D)West Nile arbovirus
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44
How is African sleeping sickness transmitted?
A)by the reduvid bugs also known as kissing bugs
B)from mosquito species
C)via the bite of the tsetse fly
D)to cattle from other livestock
A)by the reduvid bugs also known as kissing bugs
B)from mosquito species
C)via the bite of the tsetse fly
D)to cattle from other livestock
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45
A college freshman presents to student health services with a pounding headache,fever,neck rigidity and nausea. The cerebrospinal fluid is purulent with numerous white blood cells and a culture reveals Neisseria meningitidis. What are the possible complications? What makes college students at risk? How can it be prevented?
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46
What are all the animals that can get rabies? Which animals can transmit to humans and what determines human transmission ability? How should one treat an animal bite?
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47
All of the following are true about brain abscesses except:
A)microbes may reach brain from head wounds or via blood
B)they may be treated either with antibiotics or surgical removal
C)may occur in Hansen's disease
D)they can be detected by CAT scan
A)microbes may reach brain from head wounds or via blood
B)they may be treated either with antibiotics or surgical removal
C)may occur in Hansen's disease
D)they can be detected by CAT scan
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48
Prions infectivity:
A)can be destroyed by autoclaving for 1 hour
B)is reduced after formaldehyde treatment
C)can be retained in buried brains left for 3 years in soil
D)two of these choices
A)can be destroyed by autoclaving for 1 hour
B)is reduced after formaldehyde treatment
C)can be retained in buried brains left for 3 years in soil
D)two of these choices
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49
Which one of the following is not a neutrotropic viral disease?
A)West Nile fever
B)Hantavirus pulmonary syndrome
C)Polio
D)Rabies
A)West Nile fever
B)Hantavirus pulmonary syndrome
C)Polio
D)Rabies
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50
These individuals have: 
A)rabies
B)West Nile Fever
C)tetanus
D)polio
E)Hansen's disease

A)rabies
B)West Nile Fever
C)tetanus
D)polio
E)Hansen's disease
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51
Which is not a form of encephalitis?
A)Eastern equine
B)St. Louis
C)JC
D)Venezuelan equine
A)Eastern equine
B)St. Louis
C)JC
D)Venezuelan equine
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52
What do kuru,scrapie and Creutzfeldt Jakob disease all have in common?
A)all are transmitted by arthropod vectors
B)same vaccine protects against all of them
C)caused by prions
D)two of these choices
A)all are transmitted by arthropod vectors
B)same vaccine protects against all of them
C)caused by prions
D)two of these choices
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53
Who is affected by the transmissible spongiform encephalopathy called chronic wasting disease?
A)sheep and cattle
B)elk and deer
C)women in Papua New Guinea
D)Alzheimer's patients
A)sheep and cattle
B)elk and deer
C)women in Papua New Guinea
D)Alzheimer's patients
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54
Which of the following statements about brain infections is false?
A)Equine encephalitis infects horses more than humans.
B)Rabies can be transmitted by infected raccoons.
C)Poliovirus often causes no symptoms and goes undetected in small children.
D)Viral meningitis is usually self-limiting and nonfatal.
A)Equine encephalitis infects horses more than humans.
B)Rabies can be transmitted by infected raccoons.
C)Poliovirus often causes no symptoms and goes undetected in small children.
D)Viral meningitis is usually self-limiting and nonfatal.
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55
What are the two vaccines developed to prevent polio? Which vaccine would be recommended for an immunocompromised child? How about in an area that is difficult to get to and where vaccine coverage is poor? Why are there still cases of polio in the United States if vaccine coverage is excellent?
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56
The rabies virus enters the body through _____.
A)a skin wound
B)a mosquito bite
C)the placenta
D)the respiratory or gastrointestinal tracts
A)a skin wound
B)a mosquito bite
C)the placenta
D)the respiratory or gastrointestinal tracts
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