Deck 6: Osseous Tissue and Bone Structure
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Deck 6: Osseous Tissue and Bone Structure
1
Which of the following bones is classified as "irregular" in shape?
A)patella
B)frontal
C)vertebra
D)metatarsal
E)ulna
A)patella
B)frontal
C)vertebra
D)metatarsal
E)ulna
C
2
Which of the following labels best matches osteocyte?
A)stem cell
B)dissolves matrix
C)mature bone cell
D)secretes organic matrix
A)stem cell
B)dissolves matrix
C)mature bone cell
D)secretes organic matrix
C
3
The large proximal projection on the femur is termed the
A)ramus.
B)trochanter.
C)tuberosity.
D)tubercle.
E)condyle.
A)ramus.
B)trochanter.
C)tuberosity.
D)tubercle.
E)condyle.
B
4
Which of following is a function of the skeletal system?
A)body support
B)calcium homeostasis
C)protection of internal organs
D)blood cell production
E)All of the answers are correct.
A)body support
B)calcium homeostasis
C)protection of internal organs
D)blood cell production
E)All of the answers are correct.
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5
Which of the following are not components of the skeletal system?
A)tendons
B)bones
C)ligaments
D)cartilage
E)other tissues that connect bones
A)tendons
B)bones
C)ligaments
D)cartilage
E)other tissues that connect bones
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6
________ bones develop inside tendons,commonly near the knees,hands,and feet.
A)Irregular
B)Sesamoid
C)Short
D)Long
E)Flat
A)Irregular
B)Sesamoid
C)Short
D)Long
E)Flat
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7
The carpal bones are examples of ________ bones.
A)long
B)short
C)flat
D)irregular
E)sesamoid
A)long
B)short
C)flat
D)irregular
E)sesamoid
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8
Through the action of osteoclasts,
A)new bone is formed.
B)an organic framework is formed.
C)bony matrix is dissolved.
D)osteoid is calcified.
E)fractured bones regenerate.
A)new bone is formed.
B)an organic framework is formed.
C)bony matrix is dissolved.
D)osteoid is calcified.
E)fractured bones regenerate.
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9
________ are squamous stem cells that develop into osteoblasts.
A)Osteoclasts
B)Osteocytes
C)Osteomedullary cells
D)Osteoprogenitor cells
E)Squamous osteons
A)Osteoclasts
B)Osteocytes
C)Osteomedullary cells
D)Osteoprogenitor cells
E)Squamous osteons
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10
Small,oddly shaped bones that fill gaps between bones of the skull are called ________ bones.
A)irregular
B)sesamoid
C)sutural
D)sagittal
E)tendon
A)irregular
B)sesamoid
C)sutural
D)sagittal
E)tendon
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11
A rib is an example of a ________ bone.
A)long
B)short
C)flat
D)sutural
E)sesamoid
A)long
B)short
C)flat
D)sutural
E)sesamoid
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12
The region of a long bone between the end and the shaft is known as the ________.
A)diaphysis
B)epiphysis
C)osseophysis
D)metaphysis
E)medullary cavity
A)diaphysis
B)epiphysis
C)osseophysis
D)metaphysis
E)medullary cavity
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13
Bones that develop within tendons are called ________ bones.
A)irregular
B)sesamoid
C)sutural
D)Wormian
E)tendon
A)irregular
B)sesamoid
C)sutural
D)Wormian
E)tendon
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14
The smooth,rounded articular process of a bone is termed a
A)crest.
B)ridge.
C)head.
D)condyle.
E)trochlea.
A)crest.
B)ridge.
C)head.
D)condyle.
E)trochlea.
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15
Cells that secrete the organic components of the bone matrix are called
A)osteocytes.
B)osteoprogenitor cells.
C)osteoblasts.
D)osteoclasts.
E)chondrocytes.
A)osteocytes.
B)osteoprogenitor cells.
C)osteoblasts.
D)osteoclasts.
E)chondrocytes.
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16
The tip of a long bone is called the
A)epiphysis.
B)diaphysis.
C)epiphyseal plate.
D)metaphysis.
E)lamella.
A)epiphysis.
B)diaphysis.
C)epiphyseal plate.
D)metaphysis.
E)lamella.
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17
A shallow depression on a bone is termed a
A)fossa.
B)sulcus.
C)facet.
D)fissure.
E)line.
A)fossa.
B)sulcus.
C)facet.
D)fissure.
E)line.
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18
The humerus is an example of a(n)________ bone.
A)long
B)short
C)flat
D)irregular
E)sesamoid
A)long
B)short
C)flat
D)irregular
E)sesamoid
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19
Bone is composed of ________ percent cells.
A)25
B)10
C)2
D)15
E)50
A)25
B)10
C)2
D)15
E)50
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20
A hole through a bone is termed a
A)ramus.
B)foramen.
C)linea.
D)tubercle.
E)facet.
A)ramus.
B)foramen.
C)linea.
D)tubercle.
E)facet.
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21
Fat is stored within the
A)medullary cavity.
B)metaphysis.
C)spongy bone.
D)epiphysis.
E)diaphysis.
A)medullary cavity.
B)metaphysis.
C)spongy bone.
D)epiphysis.
E)diaphysis.
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22
The structural units of mature compact bone are called
A)lacunae.
B)osteocytes.
C)osteons.
D)canaliculi.
E)lamellae.
A)lacunae.
B)osteocytes.
C)osteons.
D)canaliculi.
E)lamellae.
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23
The central canal of an osteon contains
A)bone marrow.
B)osteocytes.
C)concentric lamellae.
D)blood vessels.
E)lacunae.
A)bone marrow.
B)osteocytes.
C)concentric lamellae.
D)blood vessels.
E)lacunae.
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24
The type of bone that is adapted to withstand stresses that arrive from many directions is ________ bone.
A)spongy
B)osteon
C)compact
D)lamellar
E)irregular
A)spongy
B)osteon
C)compact
D)lamellar
E)irregular
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25
The lacunae of osseous tissue contain
A)blood cells.
B)osteocytes.
C)chondroblasts.
D)bone marrow.
E)capillaries.
A)blood cells.
B)osteocytes.
C)chondroblasts.
D)bone marrow.
E)capillaries.
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26
How would removing hydroxyapatite from bone matrix affect the physical properties of a bone?
A)The bone would be less flexible.
B)The bone would be stronger.
C)The bone would be more brittle.
D)The bone would be more flexible.
E)The bone would be less compressible.
A)The bone would be less flexible.
B)The bone would be stronger.
C)The bone would be more brittle.
D)The bone would be more flexible.
E)The bone would be less compressible.
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27
The space occupied by an osteocyte is called a
A)Volkmann's canal.
B)lacuna.
C)trabecula.
D)Haversian canal.
E)Venetian canal.
A)Volkmann's canal.
B)lacuna.
C)trabecula.
D)Haversian canal.
E)Venetian canal.
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28
Which of the following chemicals is not present in bone?
A)calcium phosphate
B)collagen fibers
C)calcium carbonate
D)chondroitin sulfate
E)hydroxyapatite
A)calcium phosphate
B)collagen fibers
C)calcium carbonate
D)chondroitin sulfate
E)hydroxyapatite
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29
The ________ interactions allow bone to be strong,somewhat flexible,and highly resistant to shattering.
A)collagen-fiber
B)protein-crystal
C)mineral-crystal
D)protein-protein
E)hydroxyapatite-crystal
A)collagen-fiber
B)protein-crystal
C)mineral-crystal
D)protein-protein
E)hydroxyapatite-crystal
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30
In relationship to the diaphysis of a long bone,the osteons are
A)radial.
B)anterior.
C)parallel.
D)proximal.
E)diagonal.
A)radial.
B)anterior.
C)parallel.
D)proximal.
E)diagonal.
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31
________ cells are located in the inner cellular layer of the periosteum.
A)Osteocyte
B)Osteoclast
C)Osteoid
D)Osteoprogenitor
E)Chondroblast
A)Osteocyte
B)Osteoclast
C)Osteoid
D)Osteoprogenitor
E)Chondroblast
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32
________ marrow is found between the trabeculae of spongy bone.
A)Blue
B)Yellow
C)White
D)Gray
E)Red
A)Blue
B)Yellow
C)White
D)Gray
E)Red
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33
________ account(s)for almost two-thirds of the weight of bone.
A)Water
B)Calcium carbonate
C)Collagen fibers
D)Fluoride
E)Calcium phosphate
A)Water
B)Calcium carbonate
C)Collagen fibers
D)Fluoride
E)Calcium phosphate
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34
The interconnecting tiny arches of bone tissue found in spongy bone are called
A)osteons.
B)trabeculae.
C)concentric lamellae.
D)interstitial lamellae.
E)lacunae.
A)osteons.
B)trabeculae.
C)concentric lamellae.
D)interstitial lamellae.
E)lacunae.
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35
The most abundant cell type in bone is
A)osteoclasts.
B)osteoblasts.
C)osteolytes.
D)osteoprogenitor cells.
E)osteocytes.
A)osteoclasts.
B)osteoblasts.
C)osteolytes.
D)osteoprogenitor cells.
E)osteocytes.
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36
The femur can withstand ________ times the body weight without breaking.
A)3
B)5 to 10
C)8
D)10 to 15
E)30
A)3
B)5 to 10
C)8
D)10 to 15
E)30
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37
The lining of the medullary cavity is called the
A)endosteum.
B)periosteum.
C)epimysium.
D)perimysium.
E)perichondrium.
A)endosteum.
B)periosteum.
C)epimysium.
D)perimysium.
E)perichondrium.
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38
________ bone reduces the weight of the skeleton and reduces the load on muscles.
A)Short
B)Irregular
C)Spongy
D)Compact
E)Long
A)Short
B)Irregular
C)Spongy
D)Compact
E)Long
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39
The narrow passageways that contain cytoplasmic extensions of osteocytes are called
A)central canals.
B)lacunae.
C)canaliculi.
D)medullary cavities.
E)foramina.
A)central canals.
B)lacunae.
C)canaliculi.
D)medullary cavities.
E)foramina.
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40
Which of the following is a characteristic of bone?
A)The bone matrix is very dense and contains deposits of calcium salts.
B)The matrix of the bone contains osteoclasts.
C)Narrow channels pass through the matrix to allow for muscle attachment.
D)The matrix of bone is mostly collagen with very little calcium.
E)For strength,compact bone is organized into a meshwork of matrix called trabeculae.
A)The bone matrix is very dense and contains deposits of calcium salts.
B)The matrix of the bone contains osteoclasts.
C)Narrow channels pass through the matrix to allow for muscle attachment.
D)The matrix of bone is mostly collagen with very little calcium.
E)For strength,compact bone is organized into a meshwork of matrix called trabeculae.
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41
Intramembranous ossification begins with differentiation of ________ cells.
A)osteoclast
B)osteoprogenitor
C)mesenchymal
D)osteoblast
E)osteocyte
A)osteoclast
B)osteoprogenitor
C)mesenchymal
D)osteoblast
E)osteocyte
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42

Figure 6-1 Bone Tissue
Use Figure 6-1 to answer the following questions:
The structure labeled "3" is the result of which process?
A)bone cells adding matrix between existing osteons
B)surface growth of bone
C)remodeling of compact bone
D)remodeling of spongy bone
E)osteoporosis
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43
Bone tissue formation begins when osteoblasts secrete
A)collagen fibers.
B)mesenchyme.
C)silica.
D)hydroxyapatite.
E)calcium.
A)collagen fibers.
B)mesenchyme.
C)silica.
D)hydroxyapatite.
E)calcium.
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44
Endochondral ossification begins with the formation of a(n)
A)fibrous connective-tissue model.
B)cartilage model.
C)membranous model.
D)calcified model.
E)osteoblasts model.
A)fibrous connective-tissue model.
B)cartilage model.
C)membranous model.
D)calcified model.
E)osteoblasts model.
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45
Intramembranous ossification
A)produces flat bones as in the bones of the roof of the skull.
B)explains how a juvenile's bone can grow in length.
C)occurs in the diaphysis of a long bone.
D)occurs inside a bag of cartilage.
E)occurs in all bones before birth.
A)produces flat bones as in the bones of the roof of the skull.
B)explains how a juvenile's bone can grow in length.
C)occurs in the diaphysis of a long bone.
D)occurs inside a bag of cartilage.
E)occurs in all bones before birth.
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46

Figure 6-1 Bone Tissue
Use Figure 6-1 to answer the following questions:
Which structure is characteristic of spongy bone?
A)1
B)2
C)3
D)4
E)5
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47
The articular cartilage of a typical long bone is composed of what type of cartilage?
A)elastic cartilage
B)synovial cartilage
C)hyaline cartilage
D)fibrocartilage
E)osseous cartilage
A)elastic cartilage
B)synovial cartilage
C)hyaline cartilage
D)fibrocartilage
E)osseous cartilage
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48
Bone growth in length occurs by mitosis of
A)concentric lamellae.
B)cartilage cells in the epiphyseal side of the metaphysis.
C)growth of trabeculae.
D)osteoblasts in the endosteum.
E)cartilage cells in the diaphyseal side of the metaphysis.
A)concentric lamellae.
B)cartilage cells in the epiphyseal side of the metaphysis.
C)growth of trabeculae.
D)osteoblasts in the endosteum.
E)cartilage cells in the diaphyseal side of the metaphysis.
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49

Figure 6-1 Bone Tissue
Use Figure 6-1 to answer the following questions:
Identify the structures labeled "4."
A)concentric lamellae
B)circumferential lamellae
C)interstitial lamellae
D)trabeculae
E)periosteum
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50
The layers of bone tissue immediately deep to the periosteum are
A)circumferential lamellae.
B)osteoid plates.
C)trabeculae.
D)concentric lamellae.
E)epiphseal ridges.
A)circumferential lamellae.
B)osteoid plates.
C)trabeculae.
D)concentric lamellae.
E)epiphseal ridges.
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51
The following are important steps in the process of endochondral ossification. 1.Enlarged chondrocytes die.
2)Osteoblasts replace calcified cartilage with spongy bone.
3)Chondrocytes enlarge and the surrounding matrix begins to calcify.
4)Blood vessels invade the perichondrium.
5)Perichondrial cells become osteoblasts and produce a thin shell of bone.
The correct order for these events is
A)3,1,5,4,2
B)1,3,5,4,2
C)1,5,3,4,2
D)2,3,1,5,4
E)3,1,4,5,2
2)Osteoblasts replace calcified cartilage with spongy bone.
3)Chondrocytes enlarge and the surrounding matrix begins to calcify.
4)Blood vessels invade the perichondrium.
5)Perichondrial cells become osteoblasts and produce a thin shell of bone.
The correct order for these events is
A)3,1,5,4,2
B)1,3,5,4,2
C)1,5,3,4,2
D)2,3,1,5,4
E)3,1,4,5,2
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52
Primary ossification centers develop in long bones in the
A)proximal epiphysis.
B)periosteum.
C)metaphysis.
D)distal epiphysis.
E)diaphysis.
A)proximal epiphysis.
B)periosteum.
C)metaphysis.
D)distal epiphysis.
E)diaphysis.
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53
Which of the following is formed by intramembranous ossification?
A)roof of the skull
B)carpal bones
C)femur
D)clavicle
E)the roof of the skull and the clavicle
A)roof of the skull
B)carpal bones
C)femur
D)clavicle
E)the roof of the skull and the clavicle
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54

Figure 6-1 Bone Tissue
Use Figure 6-1 to answer the following questions:
Which structure is termed an osteon?
A)1
B)2
C)3
D)4
E)5
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55
Which statement is true regarding calcium in bone matrix?
A)Calcium is found in crystals called hydroxyapatite.
B)Calcium is secreted by osteoblasts into the matrix.
C)Once deposited,calcium cannot be removed from bone.
D)Calcium provides flexibility to the bone matrix.
E)Calcium is the organic part of the matrix.
A)Calcium is found in crystals called hydroxyapatite.
B)Calcium is secreted by osteoblasts into the matrix.
C)Once deposited,calcium cannot be removed from bone.
D)Calcium provides flexibility to the bone matrix.
E)Calcium is the organic part of the matrix.
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56

Figure 6-1 Bone Tissue
Use Figure 6-1 to answer the following questions:
Where would osteoclasts be most active?
A)1
B)2
C)3
D)4
E)5
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57
Secondary ossification centers occur
A)in the diaphysis.
B)at the periosteum.
C)in the epiphyses.
D)in the metaphyses.
E)in dermal bones.
A)in the diaphysis.
B)at the periosteum.
C)in the epiphyses.
D)in the metaphyses.
E)in dermal bones.
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58
The trabeculae of spongy bone
A)are organized parallel to the long axis of the bone.
B)are organized along stress lines.
C)are composed mostly of cartilage.
D)will collapse under stress.
E)are concentrated in the cortex of the diaphysis.
A)are organized parallel to the long axis of the bone.
B)are organized along stress lines.
C)are composed mostly of cartilage.
D)will collapse under stress.
E)are concentrated in the cortex of the diaphysis.
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59
Which of the following statements about Marfan's syndrome is false?
A)results in short,stubby fingers
B)results from a mutation
C)affects connective tissue genes
D)affects epiphyseal cartilages
E)may also cause cardiovascular problems
A)results in short,stubby fingers
B)results from a mutation
C)affects connective tissue genes
D)affects epiphyseal cartilages
E)may also cause cardiovascular problems
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60
The deposition of calcium salts in bone tissues is referred to as
A)hardening.
B)ossification.
C)calcification.
D)osteogenesis.
E)remodeling.
A)hardening.
B)ossification.
C)calcification.
D)osteogenesis.
E)remodeling.
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61
Elevated levels of calcium ion in the blood stimulate the secretion of the hormone
A)calcitonin.
B)thyroid hormone.
C)parathyroid hormone.
D)growth hormone.
E)testosterone.
A)calcitonin.
B)thyroid hormone.
C)parathyroid hormone.
D)growth hormone.
E)testosterone.
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62
Factors that are necessary for proper bone formation include all of the following,except
A)vitamin A.
B)vitamin E.
C)vitamin C.
D)the hormone thyroxine.
E)vitamin D.
A)vitamin A.
B)vitamin E.
C)vitamin C.
D)the hormone thyroxine.
E)vitamin D.
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63
When cartilage is produced at the epiphyseal side of the metaphysis at the same rate as bone is deposited on the opposite side,bones
A)grow longer.
B)grow wider.
C)become shorter.
D)become more porous and weaker.
E)become thicker.
A)grow longer.
B)grow wider.
C)become shorter.
D)become more porous and weaker.
E)become thicker.
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64
Accelerated closure of the epiphyseal plates could be caused by
A)high levels of vitamin D.
B)too much calcium in the diet.
C)elevated levels of estrogen.
D)too little thyroxine.
E)an excess of growth hormone.
A)high levels of vitamin D.
B)too much calcium in the diet.
C)elevated levels of estrogen.
D)too little thyroxine.
E)an excess of growth hormone.
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65
During appositional growth
A)bones grow longer.
B)bones grow wider.
C)bone is replaced by cartilage.
D)the epiphysis fuses with the diaphysis.
E)osteoblasts are overwhelmed by osteocytes.
A)bones grow longer.
B)bones grow wider.
C)bone is replaced by cartilage.
D)the epiphysis fuses with the diaphysis.
E)osteoblasts are overwhelmed by osteocytes.
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66

Figure 6-2 Endochondral Ossification
Use Figure 6-2 to answer the following question(s):
What type of tissue occurs at #1?
A)elastic tissue
B)fibrocartilage
C)bone
D)hyaline cartilage
E)marrow tissue
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67
Excessive growth hormone prior to puberty could result in
A)osteoporosis.
B)osteopenia.
C)rickets.
D)giantism.
E)dwarfism.
A)osteoporosis.
B)osteopenia.
C)rickets.
D)giantism.
E)dwarfism.
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68
Suppose that epiphyseal lines appear in a 10-year-old's long bones.Which of the following statements is therefore true?
A)The epiphyseal plates have ossified and further growth in length is not possible.
B)Administraton of growth hormone will stimulate future bone growth in length.
C)Osteoclasts will dissolve the metaphysis so length growth can continue until adulthood.
D)More growth will occur during the teenage years as sex hormones stimulate rebuilding of growth plates.
E)Intramembranous ossification will enable further growth in length.
A)The epiphyseal plates have ossified and further growth in length is not possible.
B)Administraton of growth hormone will stimulate future bone growth in length.
C)Osteoclasts will dissolve the metaphysis so length growth can continue until adulthood.
D)More growth will occur during the teenage years as sex hormones stimulate rebuilding of growth plates.
E)Intramembranous ossification will enable further growth in length.
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69

Figure 6-2 Endochondral Ossification
Use Figure 6-2 to answer the following question(s):
What process is shown at #6?
A)primary ossification
B)secondary ossification
C)length growth
D)width growth
E)fracture repair
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70
When production of sex hormones increases at puberty,epiphyseal plates
A)get wider.
B)become narrower.
C)increase slowly.
D)accelerate rapidly,but mostly in thickness.
E)are hardly affected.
A)get wider.
B)become narrower.
C)increase slowly.
D)accelerate rapidly,but mostly in thickness.
E)are hardly affected.
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71
A lack of exercise could
A)cause bones to become thicker.
B)cause bones to store more calcium.
C)result in porous and weak bones.
D)cause bones to become longer.
E)cause bones to lose their medullary cavity.
A)cause bones to become thicker.
B)cause bones to store more calcium.
C)result in porous and weak bones.
D)cause bones to become longer.
E)cause bones to lose their medullary cavity.
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72
When the epiphyseal plate is replaced by bone,
A)puberty begins.
B)interstitial bone growth begins.
C)appositional bone growth begins.
D)long bones have reached their adult length.
E)the bone becomes more brittle.
A)puberty begins.
B)interstitial bone growth begins.
C)appositional bone growth begins.
D)long bones have reached their adult length.
E)the bone becomes more brittle.
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73
The following are major steps in the process of intramembranous ossification: 1. Clusters of osteoblasts form osteoid that becomes mineralized.
2) Osteoblasts differentiate within mesenchymal connective tissue.
3) Spicules of bone radiate out from the ossification centers.
4) Mesenchymal cells aggregate.
The correct order for these events is:
A)4,1,2,3
B)2,1,3,4
C)4,2,1,3
D)2,3,1,4
2) Osteoblasts differentiate within mesenchymal connective tissue.
3) Spicules of bone radiate out from the ossification centers.
4) Mesenchymal cells aggregate.
The correct order for these events is:
A)4,1,2,3
B)2,1,3,4
C)4,2,1,3
D)2,3,1,4
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74
The most abundant mineral in the human body is
A)sodium.
B)potassium.
C)phosphorus.
D)calcium.
E)hydrogen.
A)sodium.
B)potassium.
C)phosphorus.
D)calcium.
E)hydrogen.
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75

Figure 6-2 Endochondral Ossification
Use Figure 6-2 to answer the following question(s):
Identify the structure at #4.
A)intramembranous bone
B)spongy bone
C)hyaline cartilage
D)periosteum
E)mesenchyme
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76
When stress is applied to a bone,
A)the minerals in the bone produce a weak electrical field that attracts osteoblasts.
B)osteoclast activity increases.
C)the bone becomes thin and brittle.
D)the bone compensates by becoming thinner in the region of stress.
E)it usually breaks.
A)the minerals in the bone produce a weak electrical field that attracts osteoblasts.
B)osteoclast activity increases.
C)the bone becomes thin and brittle.
D)the bone compensates by becoming thinner in the region of stress.
E)it usually breaks.
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77

Figure 6-2 Endochondral Ossification
Use Figure 6-2 to answer the following question(s):
Identify the structure labeled "2."
A)epiphysis
B)diaphysis
C)metaphysis
D)marrow cavity
E)trabeculae
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78
Where in the body does the production of precursors for the synthesis of calcitriol occur?
A)bone
B)kidneys
C)small intestine
D)liver
E)skin
A)bone
B)kidneys
C)small intestine
D)liver
E)skin
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79

Figure 6-2 Endochondral Ossification
Use Figure 6-2 to answer the following question(s):
Where does growth in length occur?
A)1
B)2
C)3
D)4
E)5
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80
In normal adult bones,
A)there is no turnover of minerals.
B)a portion of the protein and mineral content is replaced each year.
C)osteoblast activity exceeds osteoclast activity,once bone has been formed.
D)osteoclasts continue to be active long after osteoblast activity ceases.
E)exercise will have no effect on bone remodeling.
A)there is no turnover of minerals.
B)a portion of the protein and mineral content is replaced each year.
C)osteoblast activity exceeds osteoclast activity,once bone has been formed.
D)osteoclasts continue to be active long after osteoblast activity ceases.
E)exercise will have no effect on bone remodeling.
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