Deck 25: Population and Evolutionary Genetics

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Question
In a population of 100 individuals,49% are of the NN blood type.What percentage is expected to be MN assuming Hardy-Weinberg equilibrium conditions?

A) 9%
B) 21%
C) 42%
D) 51%
E) There is insufficient information to answer this question.
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Question
A number of mechanisms operate to maintain genetic diversity in a population.Why is such diversity favored?

A) Homozygosity is an evolutionary advantage.
B) Diversity leads to inbreeding advantages.
C) Genetic diversity may better adapt a population to inevitable changes in the environment.
D) Greater genetic diversity increases the chances of haploidy.
E) Genetic diversity helps populations avoid diploidy.
Question
Albinism is an autosomal recessive trait in humans.Assume that there are 100 albinos (aa)in a population of 1 million.How many individuals would be expected to be homozygous normal (AA)under equilibrium conditions?

A) 100
B) 10,000
C) 19,800
D) 980,100
E) 999,900
Question
What does the variable 2pq represent?
Question
In a population that meets the Hardy-Weinberg equilibrium assumptions,81% of the individuals are homozygous for a recessive allele.What percentage of the individuals would be expected to be heterozygous for this locus in the next generation?
Question
In a population of cattle,the following color distribution was noted: 36% red (RR),48% roan (Rr),and 16% white (rr).Is this population in a Hardy-Weinberg equilibrium? What will be the distribution of genotypes in the next generation if the Hardy-Weinberg assumptions are met?
Question
Assume that a trait is caused by the homozygous state of a gene that is recessive and autosomal.Nine percent of the individuals in a given population express the phenotype caused by this gene.What percentage of the individuals would be heterozygous for the gene? Assume that the population is in Hardy-Weinberg equilibrium.
Question
List at least three factors that change gene frequencies in populations.
Question
Assume that in a Hardy-Weinberg population,9% of the individuals are of the homozygous recessive phenotype.What percentage are homozygous dominant?
Question
Which method is often used to analyze proteins and nucleic acids by physical separation when estimating genetic variation in populations?

A) electrophoresis
B) centrifugation
C) absorption spectrophotometry
D) fluorometry
E) in situ hybridization
Question
List at least five of the assumptions that pertain to a population in a Hardy-Weinberg equilibrium.
Question
Give a brief definition of the term genetic equilibrium.
Question
In a population of 10,000 individuals,where 3600 are MM,1600 are NN,and 4800 are MN,what are the frequencies of the M alleles and the N alleles?
Question
What term is given to the total genetic information carried by all members of a population?

A) gene pool
B) genome
C) chromosome complement
D) breeding unit
E) race
Question
A certain form of albinism in humans is recessive and autosomal.Assume that 1% of the individuals in a given population are albino.Assuming that the population is in Hardy-Weinberg equilibrium,what percentage of the individuals in this population is expected to be heterozygous?
Question
What is the term given to a group of individuals belonging to the same species that live in a defined geographic area that actually or potentially interbreed?

A) population
B) consanguinity
C) hybrid vigor
D) genetics
E) cytogenetics
Question
What is meant by the equation p + q = 1.0?
Question
In small isolated populations,gene frequencies can fluctuate considerably.The term that applies to this circumstance is ________.

A) genetic isolation
B) allelic separation
C) natural selection
D) stabilizing selection
E) genetic drift
Question
Which general term is used to group various biological and behavioral properties of organisms that act to prevent or reduce interbreeding?

A) phyletic evolution
B) allopatric speciation
C) reproductive isolating mechanisms
D) inbreeding
E) genetic divergence
Question
Assuming that p = 0.3 for a population in Hardy-Weinberg equilibrium,what would be the expected frequency of heterozygotes for the involved allelic pair?
Question
One of the Hardy-Weinberg assumptions states that all genotypes in the population are free of selective advantage.What influence might a selective advantage of a genotype have on a Hardy-Weinberg equilibrium?
Question
What is the original source of genetic variation in a population? Which natural factors affect changes in this original variation?
Question
Define the term fitness and relate it to the meaning of selection coefficient.
Question
Which term is given to the measure of the proportion of offspring that a particular phenotype will contribute to the next generation?
Question
Contrast directional and stabilizing forms of selection.
Question
List and briefly describe three factors that contribute to the phenomenon of natural selection.
Question
One of the Hardy-Weinberg assumptions states that the population is infinitely large.What influence might a small population size have on a Hardy-Weinberg equilibrium?
Question
Provide a general definition for the term speciation.
Question
The difference between fitness of a given genotype and another genotype considered optimal is called the selection coefficient (s).What is the selection coefficient for a genotype (aa)that produces an average of 99 offspring when Aa individuals produce an average of 100 offspring?
Question
Which would change allele frequencies more quickly: selection against a dominant allele or selection against a recessive allele?
Question
What single event is probably common to all occurrences of speciation?
Question
Why are some proteins more likely than others to diverge within a species?
Question
Mutation and migration introduce new alleles into populations.What is the most likely principal force that will shift allelic frequencies within large populations?
Question
What type of evolutionary information can be gained by examining the amino acid sequence of a protein such as cytochrome c?
Question
Why is mitochondrial DNA often used in construction of phylogenetic trees?
Question
Present a rationale for using DNA sequence polymorphisms as an index of genetic diversity.Is genetic diversity directly proportional to evolutionary (phylogenetic)diversity?
Question
In zoo animals,inbreeding often occurs because of a lack of a sufficient pool of breeding individuals.Under such conditions,what two characteristics are often exhibited among inbred organisms?
Question
Suppose that a given gene undergoes a mutation to a dominant allele such that 2 out of 100,000 offspring exhibit the new mutant phenotype.Assuming that these offspring are heterozygous,what is the mutation rate for the gene?
Question
What are the genetic consequences of inbreeding?
Question
Migration occurs when individuals move between populations.Considering a single pair of alleles,A and a,what formula is used to indicate the new frequency of A in one generation of migration?
Question
In directional selection,both phenotypic extremes are equally selected against.
Question
What information have the results of mitochondrial DNA analysis offered concerning the phylogenetic relationships between Neanderthals and modern humans?
Question
In the evolutionary sense,what is meant by the term molecular clock?
Question
In large random mating populations,random genetic drift is usually a significant factor in changing gene frequencies.
Question
Would one expect a linear relationship between DNA sequence divergence and phylogenetic distance? Why or why not?
Question
Genetic drift is primarily associated with relatively small breeding populations.
Question
Evolution is dependent on genetic diversity in the evolving population.
Question
If a gene has three alleles in a population,their frequencies must add up to 1.5.
Question
In the case of complete dominance in a population in equilibrium,we cannot tell which individuals are homozygous dominants and which are heterozygous,but by knowing the frequency of the homozygous recessives,we can estimate the frequency of homozygous dominant and heterozygous genotypes.
Question
Natural selection occurs when there is nonrandom elimination of genotypes from a population due to differences in viability or reproductive success.
Question
For a given locus,in a population with two alternative alleles,the allele frequencies p + q = 1.0.
Question
Selection is the differential reproduction of genotypes,resulting from their variable fitness.
Question
Cytochrome c is a respiratory pigment found in the mitochondria of eukaryotes.Compared with some other proteins,it has changed very slowly over long periods of time.Why?
Question
What are phylogenetic trees?
Question
Inbreeding by itself can change gene frequencies.
Question
Given an inheritance pattern of incomplete dominance and 81 flowers that are red (R¹R¹),18 flowers that are pink (R¹R²),and 1 flower that is white (R²R²),the frequency of the R¹ allele is 0.9.
Question
Conservation of amino acid sequence among distantly related groups of organisms is suggestive of an important function of that sequence.
Question
Mutations are regarded as a strong evolutionary mechanism for changing allelic frequencies.
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Deck 25: Population and Evolutionary Genetics
1
In a population of 100 individuals,49% are of the NN blood type.What percentage is expected to be MN assuming Hardy-Weinberg equilibrium conditions?

A) 9%
B) 21%
C) 42%
D) 51%
E) There is insufficient information to answer this question.
C
2
A number of mechanisms operate to maintain genetic diversity in a population.Why is such diversity favored?

A) Homozygosity is an evolutionary advantage.
B) Diversity leads to inbreeding advantages.
C) Genetic diversity may better adapt a population to inevitable changes in the environment.
D) Greater genetic diversity increases the chances of haploidy.
E) Genetic diversity helps populations avoid diploidy.
C
3
Albinism is an autosomal recessive trait in humans.Assume that there are 100 albinos (aa)in a population of 1 million.How many individuals would be expected to be homozygous normal (AA)under equilibrium conditions?

A) 100
B) 10,000
C) 19,800
D) 980,100
E) 999,900
D
4
What does the variable 2pq represent?
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5
In a population that meets the Hardy-Weinberg equilibrium assumptions,81% of the individuals are homozygous for a recessive allele.What percentage of the individuals would be expected to be heterozygous for this locus in the next generation?
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6
In a population of cattle,the following color distribution was noted: 36% red (RR),48% roan (Rr),and 16% white (rr).Is this population in a Hardy-Weinberg equilibrium? What will be the distribution of genotypes in the next generation if the Hardy-Weinberg assumptions are met?
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
7
Assume that a trait is caused by the homozygous state of a gene that is recessive and autosomal.Nine percent of the individuals in a given population express the phenotype caused by this gene.What percentage of the individuals would be heterozygous for the gene? Assume that the population is in Hardy-Weinberg equilibrium.
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8
List at least three factors that change gene frequencies in populations.
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9
Assume that in a Hardy-Weinberg population,9% of the individuals are of the homozygous recessive phenotype.What percentage are homozygous dominant?
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10
Which method is often used to analyze proteins and nucleic acids by physical separation when estimating genetic variation in populations?

A) electrophoresis
B) centrifugation
C) absorption spectrophotometry
D) fluorometry
E) in situ hybridization
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11
List at least five of the assumptions that pertain to a population in a Hardy-Weinberg equilibrium.
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12
Give a brief definition of the term genetic equilibrium.
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13
In a population of 10,000 individuals,where 3600 are MM,1600 are NN,and 4800 are MN,what are the frequencies of the M alleles and the N alleles?
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14
What term is given to the total genetic information carried by all members of a population?

A) gene pool
B) genome
C) chromosome complement
D) breeding unit
E) race
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Unlock for access to all 58 flashcards in this deck.
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k this deck
15
A certain form of albinism in humans is recessive and autosomal.Assume that 1% of the individuals in a given population are albino.Assuming that the population is in Hardy-Weinberg equilibrium,what percentage of the individuals in this population is expected to be heterozygous?
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
16
What is the term given to a group of individuals belonging to the same species that live in a defined geographic area that actually or potentially interbreed?

A) population
B) consanguinity
C) hybrid vigor
D) genetics
E) cytogenetics
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Unlock for access to all 58 flashcards in this deck.
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k this deck
17
What is meant by the equation p + q = 1.0?
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k this deck
18
In small isolated populations,gene frequencies can fluctuate considerably.The term that applies to this circumstance is ________.

A) genetic isolation
B) allelic separation
C) natural selection
D) stabilizing selection
E) genetic drift
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
19
Which general term is used to group various biological and behavioral properties of organisms that act to prevent or reduce interbreeding?

A) phyletic evolution
B) allopatric speciation
C) reproductive isolating mechanisms
D) inbreeding
E) genetic divergence
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Unlock for access to all 58 flashcards in this deck.
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k this deck
20
Assuming that p = 0.3 for a population in Hardy-Weinberg equilibrium,what would be the expected frequency of heterozygotes for the involved allelic pair?
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k this deck
21
One of the Hardy-Weinberg assumptions states that all genotypes in the population are free of selective advantage.What influence might a selective advantage of a genotype have on a Hardy-Weinberg equilibrium?
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k this deck
22
What is the original source of genetic variation in a population? Which natural factors affect changes in this original variation?
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k this deck
23
Define the term fitness and relate it to the meaning of selection coefficient.
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24
Which term is given to the measure of the proportion of offspring that a particular phenotype will contribute to the next generation?
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25
Contrast directional and stabilizing forms of selection.
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26
List and briefly describe three factors that contribute to the phenomenon of natural selection.
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27
One of the Hardy-Weinberg assumptions states that the population is infinitely large.What influence might a small population size have on a Hardy-Weinberg equilibrium?
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28
Provide a general definition for the term speciation.
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29
The difference between fitness of a given genotype and another genotype considered optimal is called the selection coefficient (s).What is the selection coefficient for a genotype (aa)that produces an average of 99 offspring when Aa individuals produce an average of 100 offspring?
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30
Which would change allele frequencies more quickly: selection against a dominant allele or selection against a recessive allele?
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31
What single event is probably common to all occurrences of speciation?
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32
Why are some proteins more likely than others to diverge within a species?
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33
Mutation and migration introduce new alleles into populations.What is the most likely principal force that will shift allelic frequencies within large populations?
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34
What type of evolutionary information can be gained by examining the amino acid sequence of a protein such as cytochrome c?
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35
Why is mitochondrial DNA often used in construction of phylogenetic trees?
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36
Present a rationale for using DNA sequence polymorphisms as an index of genetic diversity.Is genetic diversity directly proportional to evolutionary (phylogenetic)diversity?
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37
In zoo animals,inbreeding often occurs because of a lack of a sufficient pool of breeding individuals.Under such conditions,what two characteristics are often exhibited among inbred organisms?
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k this deck
38
Suppose that a given gene undergoes a mutation to a dominant allele such that 2 out of 100,000 offspring exhibit the new mutant phenotype.Assuming that these offspring are heterozygous,what is the mutation rate for the gene?
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39
What are the genetic consequences of inbreeding?
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40
Migration occurs when individuals move between populations.Considering a single pair of alleles,A and a,what formula is used to indicate the new frequency of A in one generation of migration?
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41
In directional selection,both phenotypic extremes are equally selected against.
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42
What information have the results of mitochondrial DNA analysis offered concerning the phylogenetic relationships between Neanderthals and modern humans?
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43
In the evolutionary sense,what is meant by the term molecular clock?
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44
In large random mating populations,random genetic drift is usually a significant factor in changing gene frequencies.
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k this deck
45
Would one expect a linear relationship between DNA sequence divergence and phylogenetic distance? Why or why not?
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46
Genetic drift is primarily associated with relatively small breeding populations.
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47
Evolution is dependent on genetic diversity in the evolving population.
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48
If a gene has three alleles in a population,their frequencies must add up to 1.5.
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49
In the case of complete dominance in a population in equilibrium,we cannot tell which individuals are homozygous dominants and which are heterozygous,but by knowing the frequency of the homozygous recessives,we can estimate the frequency of homozygous dominant and heterozygous genotypes.
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50
Natural selection occurs when there is nonrandom elimination of genotypes from a population due to differences in viability or reproductive success.
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51
For a given locus,in a population with two alternative alleles,the allele frequencies p + q = 1.0.
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52
Selection is the differential reproduction of genotypes,resulting from their variable fitness.
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53
Cytochrome c is a respiratory pigment found in the mitochondria of eukaryotes.Compared with some other proteins,it has changed very slowly over long periods of time.Why?
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54
What are phylogenetic trees?
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55
Inbreeding by itself can change gene frequencies.
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56
Given an inheritance pattern of incomplete dominance and 81 flowers that are red (R¹R¹),18 flowers that are pink (R¹R²),and 1 flower that is white (R²R²),the frequency of the R¹ allele is 0.9.
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57
Conservation of amino acid sequence among distantly related groups of organisms is suggestive of an important function of that sequence.
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k this deck
58
Mutations are regarded as a strong evolutionary mechanism for changing allelic frequencies.
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