Deck 14: Treatments for Anxiety Disorders

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Question
A great fear of tight spaces that prevents a person from riding on elevators is an example of …

A) panic disorder.
B) specific phobia.
C) agoraphobia.
D) social anxiety disorder.
Use Space or
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to flip the card.
Question
Deciding not to go to a party because of a belief that those at the party will laugh about you or that you may embarass yourself is an example of…

A) specific phobia.
B) panic disorder.
C) generalized anxiety disorder.
D) agoraphobia.
Question
Finding the hypothalamus and locus coeruleus highly active during a fear situation likely means…

A) the feelings of fear are rapidly declining.
B) a person cannot make a decision.
C) the person rapidly decides plans on how to respond.
D) the sympathetic nervous system is highly activated.
Question
A fear response to a loud but undefined noise was likely only processed through the…

A) thalamo-amygdala pathway.
B) cerebellum-reticular formation group.
C) thalamo-cortical-amygdala pathway.
D) mesolimbic pathway.
Question
Electrical stimulation of the amygdala would likely result in…

A) reinforcing effects.
B) memory loss.
C) a strong fear response.
D) drug-seeking behavior.
Question
A fear response occurring to a loud car horn appearing to your right was likely processed through the…

A) thalamo-cortical-amygdala pathway
B) thalmo-amygdala pathway.
C) mesocortical pathway.
D) auditory-thalamo-prefrontal cortical pathway.
Question
A person who engages in a ritual of checking the locks on his doors multiple times before going to bed could have …

A) a specific phobia.
B) posttraumatic stress disorder.
C) obsessive compulsive disorder.
D) generalized anxiety disorder.
Question
The lifetime prevalence in the U.S.of having some type of anxiety disorder is approximately…

A) 0%.
B) 10%.
C) 30%.
D) 60%.
Question
An immediate decline in being afraid after realizing that a loud noise you heard is not a threat is due to a signal produced by the …

A) thalamus.
B) prefrontal cortex.
C) hippocampus.
D) amygdala.
Question
If a person who is known as someone who worries about everything and generally upset from these worries likely has…

A) social anxiety disorder.
B) generalized anxiety disorder.
C) panic disorder.
D) obsessive compulsive disorder.
Question
A(n)_____________ is an abrupt and possibly unexpected strong physiological reaction accompanied by intense apprehension,fearfulness,or terror.

A) fight-or-flight response
B) agorophobic reaction
C) obsession
D) panic attack
Question
If someone is afraid to a give a presentation because he thinks the audience will not like his ideas,this is an example of…

A) anxiety.
B) fear.
C) a fight-or-flight response.
D) panic.
Question
As part of the process for fear stimuli,the hippocampus…

A) provides information about the context of stimuli.
B) provides unrefined information about the stimulus.
C) indicates if the stimulus is visual or auditory.
D) indicates the magnitude of the stimulus.
Question
Increased activity in the _____________ is associated with fear and anxiety.

A) hippocampus
B) amygdala
C) prefrontal cortex
D) nucleus accumbens
Question
All of the following disorders involving anxiety are at least partly mediated by amygdala except…

A) panic disorder.
B) social phobia.
C) obsessive compulsive disorder.
D) posttraumatic stress disorder.
Question
A persistent state of physiological arousal or exaggerated response to certain stimuli,particularly those associated with a traumatic event,occurs with …

A) posttraumatic stress disorder.
B) agoraphonia.
C) generalized anxiety disorder.
D) social anxiety disorder.
Question
A gene rapidly activating in response to a stimulus is referred to as a(n)…

A) stimulus gene.
B) early immediate gene.
C) context gene.
D) quick response gene.
Question
A negative emotion caused by a real or perceived imminent danger or threat is called…

A) aggression.
B) anxiety.
C) fight or flight.
D) fear.
Question
Worry and distress concerning potential events or outcomes is referred to as …

A) aggression.
B) concern.
C) anxiety.
D) fear.
Question
A quick decision on how to respond to a fear stimulus is made in the…

A) prefrontal cortex.
B) amygdala.
C) hippocampus.
D) thalamus.
Question
Accidental overdose may occur due to …

A) forgetting taking the medication earlier.
B) taking an incorrect dose.
C) having a polymorphism for barbiturate biotransformation.
D) COPD.
Question
High levels of cortisol can cause…

A) damage to the hypothalamus.
B) diminished activity in the prefrontal cortex.
C) elevated activity in the amygdala.
D) damage to the hippocampus.
Question
Your friend has been dealing with a highly stressful work situation and recently has appeared very tired and seems to constantly have aches and pains.If she has the general adaptation syndrome,which stage is she likely in?

A) Exhaustion
B) Alarm
C) Resistance
D) Autoimmune
Question
A hormone that serves as an indicator of stress is…

A) neuropeptide Y.
B) testosterone.
C) cortisol.
D) prolactin.
Question
A barbiturate that is only effective for 30 minutes would be classifed as a(n)…

A) short-acting barbiturate.
B) ultrashort-acting barbiturate.
C) intermediate acting barbiturate.
D) long-acting barbiturate.
Question
During which phase of PTSD do studies consistently find higher levels of cortisol?

A) panic phase.
B) tonic phase.
C) phasic phase.
D) avoidance phase.
Question
The first anxiolytic drug was a(n)…

A) antidepressant drug.
B) barbiturate.
C) idoleamine.
D) benzodiazepine.
Question
A barbiturate that is long-acting typically has…

A) many active metabolites.
B) poor lipid solubility.
C) poor absorption.
D) a large dose.
Question
A drug specifically used for the treatment of anxiety is called a(n)…

A) tranquilizer.
B) bromide.
C) anti-anxiety drug.
D) anxiolytic.
Question
Barbiturates produce depressant effects as positive modulators for…

A) NDMA receptors.
B) GABAA receptors.
C) dopamine D₂ receptors.
D) serotonin 5-HT₂C receptors.
Question
Activation of the locus coeruleus during a fear reaction causes…

A) the adrenal gland to release norepinephrine and epinephrine.
B) signals to be sent to the prefrontal cortex.
C) an increase in sensory processing by the thalamus.
D) a rapid decrease in the activity of the amygdala.
Question
Hyperventilation and breathing in CO₂ can both produce…

A) enhanced decision making.
B) rewarding effects.
C) panic.
D) generalized anxiety disorder.
Question
Alarm is the first stage in…

A) general adaptation syndrome.
B) generalized anxiety disorder.
C) posttraumatic stress disorder.
D) a fight-or-flight response
Question
During general adaptation syndrome,a sustained level of physiological arousal characterizes the __________ stage.

A) resistance
B) alarm
C) denial
D) exhaustion
Question
A person with PTSD who has a sudden,stressful response to a memory of a traumatic event would be in …

A) a tonic phase.
B) an active phase.
C) a phasic phase.
D) an avoidance phase.
Question
Anxiety,muscle weakness,and abdominal pain from abruptly quitting a barbiturate is called a(n)…

A) withdrawal disorder.
B) barbiturate abstinence syndrome.
C) anxiolytic withdrawal disorder.
D) tranquilier abstinence syndrome.
Question
The adrenal gland releases cortisol after the pituitary gland releases…

A) prolactin.
B) adrenocorticotropic hormone.
C) melatonin.
D) hydrocortisol.
Question
After a doctor performs a routine blood analysis and finds unusually high levels of cortisol,what might she ask her patient?

A) Have you been facing a lot of stress lately?
B) Have you been eating foods high in cholesterol?
C) Have you been abusing any drugs?
D) Have you been feeling depressed?
Question
Chronic use of barbiturates produces tolerance for anxiolytic effects but not for its…

A) anesthetic effects.
B) hypnotic effects.
C) reinforcing effects.
D) respiratory depression effects.
Question
The following indicate that barbiturates have abuse potential except…

A) nonhuman primates self-administer barbiturates.
B) in human laboratory studies, humans prefer barbiturates just as much as morphine.
C) barbiturates reduce stress, thereby serving as negative reinforcers.
D) human participants rate barbiturates highly on liking scales.
Question
If alcohol were consumed after taking a barbiturate…

A) it would strengthen the barbiturate's effects.
B) it would cancel the barbiturate's effects.
C) it would increase the rewarding effects but not the respiratory depressant effects of the barbiturate.
D) there would be no additional effects.
Question
If a pharmacologist wanted to develop a sleep-inducing drug that did not reduce anxiety,which site should she target the drug for?

A) BZ 2 site.
B) BZ 1 site.
C) barbiturate site.
D) ethanol site.
Question
The BZ I site is found on the _______ subunit of the GABAA receptor.

A) alpha1
B) beta3
C) alpha3
D) alpha5
Question
Benzodiazepines act as ________________ for GABAA receptors.

A) positive modulators
B) agonists
C) partial agonists
D) antagonists
Question
BZ I sites are found in the following structures except…

A) cerebellum.
B) substantia nigra.
C) hippocampus.
D) thalamus.
Question
Depression,anxiety,suicidality,and convulsions occurring from abupt withdrawal from a benzodiazepine is called the…

A) tranquilizer withdrawal syndrome.
B) benzodiazepine withdrawal syndrome.
C) anxiolytic withdrawal disorder.
D) benzodiazepine depressive disorder.
Question
The benzodiazepine site is located on…

A) an alpha subunit of the NMDA receptor.
B) an alpha subunit of the GABAA receptor.
C) a beta subunit of the NMDA receptor.
D) a beta subunit of the GABAA receptor.
Question
Use of alcohol with a benzodiazepine is associated with all of the following except…

A) greater anxiety.
B) greater risk of drug-induced death.
C) harm caused by overdose.
D) higher rates of accidental injury.
Question
People are more likely to report enjoying the effects of benzodiazepines if

A) they are at least light drinkers.
B) they are moderate or heavy drinkers.
C) they have a polymorphism of the CYP-2C19 gene.
D) they are current smokers.
Question
The BZ II site is found on the _______ subunit of the GABAA receptor.

A) alpha1
B) beta3
C) alpha2
D) alpha6
Question
A benzodiazepine will have long-lasting effects if…

A) it has poor lipid solubility.
B) it has active metabolites.
C) someone has a low density of GABAA receptors.
D) someone has also taken a barbiturate.
Question
The first marketed benzodiazepine drug was…

A) clonazepam.
B) alprazolam.
C) chlordiazepoxide.
D) diazepam.
Question
Benzodiazepines have a high affinity for the…

A) beta3 subunit.
B) alpha1 subunit.
C) alpha3 subunit.
D) alpha5 subunit
Question
If a pharmacologist wanted to develop a benzodiazepine with a low likehood of producing drowsiness,she specifically targets the drug for the…

A) BZ 2 site.
B) BZ 1 site.
C) barbiturate site.
D) ethanol site.
Question
The cognitive-impairing effects of barbiturates occur by inhbition of the…

A) hippocampus.
B) amygdala.
C) medulla.
D) cerebral cortex.
Question
Respiratory depression occurs when barbiturates inhibit activity in the…

A) amygdala.
B) medulla.
C) thalamus.
D) prefrontal cortex.
Question
A drug that might counteract the effects of a barbiturate would likely…

A) block calcium channels.
B) serve as an antagonist for NMDA receptors.
C) serve as a positive modulator for GABAA receptors.
D) serve as an antagonist for GABAA receptors.
Question
A drug that both calms a person down but also is capable to inducing sleep is called a(n)…

A) depressant-anesthetic.
B) sedative-anesthetic.
C) sedative-hypnotic.
D) tranquilizing depressant.
Question
A polymorphism of the CYP-2C19 gene causing slow metabolism of benzodiazepine will cause…

A) weaker anxiolytic effects.
B) weaker passage through the blood-brain barrier.
C) greater likelihood of tolerance.
D) longer-lasting effects.
Question
The following are reasons that benzodiazepine may be addictive except…

A) physiological withdrawal effects.
B) cravings for benzodiazepines.
C) greater likelihood to enjoy the effects of benzodiazepines in moderate drinkers.
D) greater likelihood of poor decision making when taking benzodiazepines.
Question
A chemical transmitter released from glial cells is called a(n)…

A) glial-neurotransmitter
B) glial cell-derived chemical transmitter.
C) endotransmitter.
D) gliotransmitter.
Question
An endogenous substance that binds to benzodiazepine sites is called a(n)…

A) endozepine.
B) endobenzodiapine.
C) benzopeptide.
D) pseudobenzamide.
Question
In addition to their efficacy for depression,antidepressant drugs also treat…

A) anxiety disorders.
B) pain disorders.
C) memory disorders.
D) sleep disorders.
Question
Z-drugs exhibit their effects by acting as…

A) a positive modulator for the BZ I site.
B) an agonist for the GABA receptor.
C) a positive modulator for the BZ II site.
D) a negative modulator for the NMDA receptor.
Question
Buspirone is an anxiolytic drug that acts by…

A) partial agonism of 5-HT₁A receptors.
B) positive modulation of GABAA receptors.
C) negative modulation of NMDA receptors.
D) antagonism of 5-HT₂C receptors.
Question
Combining a 5-HT₁A receptor antagonist with an SSRI would likely…

A) increase the risk of adverse effects.
B) shorten the response time for an anxiolytic effect.
C) improve anxiolytic effects but worsen depressive effects.
D) diminish an antidepressant's ability to reduce anxiety.
Question
The activation of presynaptic 5-HT₁A receptors causes…

A) a decrease in serotonin reuptake.
B) an increased release of serotonin from serotonin neurons.
C) an inhibition of serotonin neurons.
D) a positive feedback onto other serotonin neurons.
Question
In an elevated plus maze,anxiolytic-like effects are shown if a lab rat…

A) spends more time in the open arms than closed arms.
B) overall activity in the maze increases.
C) spends most of its time in the middle of the maze.
D) spends more time in the closed arms than open arms.
Question
For the treatment of obsessive compulsive disorder,antidepressant drugs…

A) are effective only when combined with an antipsychotic drug.
B) worsen OCD symptoms.
C) do not adequately reduce its symptoms.
D) require a longer treatment time than for other anxiety disorders.
Question
Antagonism of alpha2 adrenoceptor acting as heteroceptors on serotonin axon terminals will…

A) increase serotonin release.
B) decrease serotonin release.
C) increase norepinephrine release.
D) decrease norepinephrine release.
Question
The drug zolpidem (Ambien)is an example of a …

A) antihistamine.
B) barbiturate hypnotic.
C) benzodiazepine drug.
D) Z-drug.
Question
BZ II sites are found in the…

A) amygdala.
B) substantia nigra.
C) thalamus.
D) cerebellum.
Question
The existence of benzodiazepine sites on GABAA receptors suggests that …

A) benzodiazepines are made naturally in plants.
B) there are chemical in the brain that bind to these sites.
C) the brain is naturally responsive to depressant drugs.
D) there are benzodiazepine sites on GABAB receptors.
Question
Approximately how many patients with anxiety disorder fail to respond adequately to antidepressant medications ?

A) one-eighth
B) one-third
C) half
D) three-fourth
Question
The first-line treatments for anxiety disorders are…

A) antidepressant drugs.
B) benzodiazepines.
C) barbiturates.
D) anticonvulsants.
Question
Extended release tablets have been developed for buspirone because…

A) buspirone acts too quickly for anxiolytic effects to occur.
B) buspirone otherwise degrades rapidly in the stomach.
C) users become impatient and fail to take subsequent administrations of the drug.
D) buspirone's active metabolites are ineffective for treating anxiety symptoms.
Question
Why might an anticonvulsant drug be effective for anxiety?

A) It exhibits neuroprotective effects.
B) It is a positive modulator for GABAA receptors.
C) It is an antagonist for NMDA receptors.
D) It is a partial agonist GABAA receptors.
Question
Approximately how much buspirone is broken down by enzymes in the stomach?

A) 10%
B) 25%
C) 45%
D) 90%
Question
Engaging in walking,driving,doing laundry,or eating while asleep are examples of …

A) drug-induced sleep walking.
B) subconscious behaviors.
C) hypnosis.
D) sleep-related complex behaviors.
Question
An increased risk of suicide when first taking an antidepressant drug may be due to…

A) onset of anxiety.
B) increase in adverse effects.
C) activation of presynaptic 5-HT₁A receptors.
D) blockage of serotonin membrane transporters.
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Deck 14: Treatments for Anxiety Disorders
1
A great fear of tight spaces that prevents a person from riding on elevators is an example of …

A) panic disorder.
B) specific phobia.
C) agoraphobia.
D) social anxiety disorder.
B
2
Deciding not to go to a party because of a belief that those at the party will laugh about you or that you may embarass yourself is an example of…

A) specific phobia.
B) panic disorder.
C) generalized anxiety disorder.
D) agoraphobia.
D
3
Finding the hypothalamus and locus coeruleus highly active during a fear situation likely means…

A) the feelings of fear are rapidly declining.
B) a person cannot make a decision.
C) the person rapidly decides plans on how to respond.
D) the sympathetic nervous system is highly activated.
D
4
A fear response to a loud but undefined noise was likely only processed through the…

A) thalamo-amygdala pathway.
B) cerebellum-reticular formation group.
C) thalamo-cortical-amygdala pathway.
D) mesolimbic pathway.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
5
Electrical stimulation of the amygdala would likely result in…

A) reinforcing effects.
B) memory loss.
C) a strong fear response.
D) drug-seeking behavior.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
6
A fear response occurring to a loud car horn appearing to your right was likely processed through the…

A) thalamo-cortical-amygdala pathway
B) thalmo-amygdala pathway.
C) mesocortical pathway.
D) auditory-thalamo-prefrontal cortical pathway.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
7
A person who engages in a ritual of checking the locks on his doors multiple times before going to bed could have …

A) a specific phobia.
B) posttraumatic stress disorder.
C) obsessive compulsive disorder.
D) generalized anxiety disorder.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
8
The lifetime prevalence in the U.S.of having some type of anxiety disorder is approximately…

A) 0%.
B) 10%.
C) 30%.
D) 60%.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
9
An immediate decline in being afraid after realizing that a loud noise you heard is not a threat is due to a signal produced by the …

A) thalamus.
B) prefrontal cortex.
C) hippocampus.
D) amygdala.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
10
If a person who is known as someone who worries about everything and generally upset from these worries likely has…

A) social anxiety disorder.
B) generalized anxiety disorder.
C) panic disorder.
D) obsessive compulsive disorder.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
11
A(n)_____________ is an abrupt and possibly unexpected strong physiological reaction accompanied by intense apprehension,fearfulness,or terror.

A) fight-or-flight response
B) agorophobic reaction
C) obsession
D) panic attack
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
12
If someone is afraid to a give a presentation because he thinks the audience will not like his ideas,this is an example of…

A) anxiety.
B) fear.
C) a fight-or-flight response.
D) panic.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
13
As part of the process for fear stimuli,the hippocampus…

A) provides information about the context of stimuli.
B) provides unrefined information about the stimulus.
C) indicates if the stimulus is visual or auditory.
D) indicates the magnitude of the stimulus.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
14
Increased activity in the _____________ is associated with fear and anxiety.

A) hippocampus
B) amygdala
C) prefrontal cortex
D) nucleus accumbens
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Unlock Deck
k this deck
15
All of the following disorders involving anxiety are at least partly mediated by amygdala except…

A) panic disorder.
B) social phobia.
C) obsessive compulsive disorder.
D) posttraumatic stress disorder.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
16
A persistent state of physiological arousal or exaggerated response to certain stimuli,particularly those associated with a traumatic event,occurs with …

A) posttraumatic stress disorder.
B) agoraphonia.
C) generalized anxiety disorder.
D) social anxiety disorder.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
17
A gene rapidly activating in response to a stimulus is referred to as a(n)…

A) stimulus gene.
B) early immediate gene.
C) context gene.
D) quick response gene.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
18
A negative emotion caused by a real or perceived imminent danger or threat is called…

A) aggression.
B) anxiety.
C) fight or flight.
D) fear.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
19
Worry and distress concerning potential events or outcomes is referred to as …

A) aggression.
B) concern.
C) anxiety.
D) fear.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
20
A quick decision on how to respond to a fear stimulus is made in the…

A) prefrontal cortex.
B) amygdala.
C) hippocampus.
D) thalamus.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
21
Accidental overdose may occur due to …

A) forgetting taking the medication earlier.
B) taking an incorrect dose.
C) having a polymorphism for barbiturate biotransformation.
D) COPD.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
22
High levels of cortisol can cause…

A) damage to the hypothalamus.
B) diminished activity in the prefrontal cortex.
C) elevated activity in the amygdala.
D) damage to the hippocampus.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
23
Your friend has been dealing with a highly stressful work situation and recently has appeared very tired and seems to constantly have aches and pains.If she has the general adaptation syndrome,which stage is she likely in?

A) Exhaustion
B) Alarm
C) Resistance
D) Autoimmune
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
24
A hormone that serves as an indicator of stress is…

A) neuropeptide Y.
B) testosterone.
C) cortisol.
D) prolactin.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
25
A barbiturate that is only effective for 30 minutes would be classifed as a(n)…

A) short-acting barbiturate.
B) ultrashort-acting barbiturate.
C) intermediate acting barbiturate.
D) long-acting barbiturate.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
26
During which phase of PTSD do studies consistently find higher levels of cortisol?

A) panic phase.
B) tonic phase.
C) phasic phase.
D) avoidance phase.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
27
The first anxiolytic drug was a(n)…

A) antidepressant drug.
B) barbiturate.
C) idoleamine.
D) benzodiazepine.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
28
A barbiturate that is long-acting typically has…

A) many active metabolites.
B) poor lipid solubility.
C) poor absorption.
D) a large dose.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
29
A drug specifically used for the treatment of anxiety is called a(n)…

A) tranquilizer.
B) bromide.
C) anti-anxiety drug.
D) anxiolytic.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
30
Barbiturates produce depressant effects as positive modulators for…

A) NDMA receptors.
B) GABAA receptors.
C) dopamine D₂ receptors.
D) serotonin 5-HT₂C receptors.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
31
Activation of the locus coeruleus during a fear reaction causes…

A) the adrenal gland to release norepinephrine and epinephrine.
B) signals to be sent to the prefrontal cortex.
C) an increase in sensory processing by the thalamus.
D) a rapid decrease in the activity of the amygdala.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
32
Hyperventilation and breathing in CO₂ can both produce…

A) enhanced decision making.
B) rewarding effects.
C) panic.
D) generalized anxiety disorder.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
33
Alarm is the first stage in…

A) general adaptation syndrome.
B) generalized anxiety disorder.
C) posttraumatic stress disorder.
D) a fight-or-flight response
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
34
During general adaptation syndrome,a sustained level of physiological arousal characterizes the __________ stage.

A) resistance
B) alarm
C) denial
D) exhaustion
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
35
A person with PTSD who has a sudden,stressful response to a memory of a traumatic event would be in …

A) a tonic phase.
B) an active phase.
C) a phasic phase.
D) an avoidance phase.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
36
Anxiety,muscle weakness,and abdominal pain from abruptly quitting a barbiturate is called a(n)…

A) withdrawal disorder.
B) barbiturate abstinence syndrome.
C) anxiolytic withdrawal disorder.
D) tranquilier abstinence syndrome.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
37
The adrenal gland releases cortisol after the pituitary gland releases…

A) prolactin.
B) adrenocorticotropic hormone.
C) melatonin.
D) hydrocortisol.
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
38
After a doctor performs a routine blood analysis and finds unusually high levels of cortisol,what might she ask her patient?

A) Have you been facing a lot of stress lately?
B) Have you been eating foods high in cholesterol?
C) Have you been abusing any drugs?
D) Have you been feeling depressed?
Unlock Deck
Unlock for access to all 114 flashcards in this deck.
Unlock Deck
k this deck
39
Chronic use of barbiturates produces tolerance for anxiolytic effects but not for its…

A) anesthetic effects.
B) hypnotic effects.
C) reinforcing effects.
D) respiratory depression effects.
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40
The following indicate that barbiturates have abuse potential except…

A) nonhuman primates self-administer barbiturates.
B) in human laboratory studies, humans prefer barbiturates just as much as morphine.
C) barbiturates reduce stress, thereby serving as negative reinforcers.
D) human participants rate barbiturates highly on liking scales.
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41
If alcohol were consumed after taking a barbiturate…

A) it would strengthen the barbiturate's effects.
B) it would cancel the barbiturate's effects.
C) it would increase the rewarding effects but not the respiratory depressant effects of the barbiturate.
D) there would be no additional effects.
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42
If a pharmacologist wanted to develop a sleep-inducing drug that did not reduce anxiety,which site should she target the drug for?

A) BZ 2 site.
B) BZ 1 site.
C) barbiturate site.
D) ethanol site.
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43
The BZ I site is found on the _______ subunit of the GABAA receptor.

A) alpha1
B) beta3
C) alpha3
D) alpha5
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44
Benzodiazepines act as ________________ for GABAA receptors.

A) positive modulators
B) agonists
C) partial agonists
D) antagonists
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45
BZ I sites are found in the following structures except…

A) cerebellum.
B) substantia nigra.
C) hippocampus.
D) thalamus.
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46
Depression,anxiety,suicidality,and convulsions occurring from abupt withdrawal from a benzodiazepine is called the…

A) tranquilizer withdrawal syndrome.
B) benzodiazepine withdrawal syndrome.
C) anxiolytic withdrawal disorder.
D) benzodiazepine depressive disorder.
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47
The benzodiazepine site is located on…

A) an alpha subunit of the NMDA receptor.
B) an alpha subunit of the GABAA receptor.
C) a beta subunit of the NMDA receptor.
D) a beta subunit of the GABAA receptor.
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48
Use of alcohol with a benzodiazepine is associated with all of the following except…

A) greater anxiety.
B) greater risk of drug-induced death.
C) harm caused by overdose.
D) higher rates of accidental injury.
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49
People are more likely to report enjoying the effects of benzodiazepines if

A) they are at least light drinkers.
B) they are moderate or heavy drinkers.
C) they have a polymorphism of the CYP-2C19 gene.
D) they are current smokers.
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50
The BZ II site is found on the _______ subunit of the GABAA receptor.

A) alpha1
B) beta3
C) alpha2
D) alpha6
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51
A benzodiazepine will have long-lasting effects if…

A) it has poor lipid solubility.
B) it has active metabolites.
C) someone has a low density of GABAA receptors.
D) someone has also taken a barbiturate.
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52
The first marketed benzodiazepine drug was…

A) clonazepam.
B) alprazolam.
C) chlordiazepoxide.
D) diazepam.
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53
Benzodiazepines have a high affinity for the…

A) beta3 subunit.
B) alpha1 subunit.
C) alpha3 subunit.
D) alpha5 subunit
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54
If a pharmacologist wanted to develop a benzodiazepine with a low likehood of producing drowsiness,she specifically targets the drug for the…

A) BZ 2 site.
B) BZ 1 site.
C) barbiturate site.
D) ethanol site.
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55
The cognitive-impairing effects of barbiturates occur by inhbition of the…

A) hippocampus.
B) amygdala.
C) medulla.
D) cerebral cortex.
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56
Respiratory depression occurs when barbiturates inhibit activity in the…

A) amygdala.
B) medulla.
C) thalamus.
D) prefrontal cortex.
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57
A drug that might counteract the effects of a barbiturate would likely…

A) block calcium channels.
B) serve as an antagonist for NMDA receptors.
C) serve as a positive modulator for GABAA receptors.
D) serve as an antagonist for GABAA receptors.
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58
A drug that both calms a person down but also is capable to inducing sleep is called a(n)…

A) depressant-anesthetic.
B) sedative-anesthetic.
C) sedative-hypnotic.
D) tranquilizing depressant.
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59
A polymorphism of the CYP-2C19 gene causing slow metabolism of benzodiazepine will cause…

A) weaker anxiolytic effects.
B) weaker passage through the blood-brain barrier.
C) greater likelihood of tolerance.
D) longer-lasting effects.
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60
The following are reasons that benzodiazepine may be addictive except…

A) physiological withdrawal effects.
B) cravings for benzodiazepines.
C) greater likelihood to enjoy the effects of benzodiazepines in moderate drinkers.
D) greater likelihood of poor decision making when taking benzodiazepines.
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61
A chemical transmitter released from glial cells is called a(n)…

A) glial-neurotransmitter
B) glial cell-derived chemical transmitter.
C) endotransmitter.
D) gliotransmitter.
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62
An endogenous substance that binds to benzodiazepine sites is called a(n)…

A) endozepine.
B) endobenzodiapine.
C) benzopeptide.
D) pseudobenzamide.
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63
In addition to their efficacy for depression,antidepressant drugs also treat…

A) anxiety disorders.
B) pain disorders.
C) memory disorders.
D) sleep disorders.
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64
Z-drugs exhibit their effects by acting as…

A) a positive modulator for the BZ I site.
B) an agonist for the GABA receptor.
C) a positive modulator for the BZ II site.
D) a negative modulator for the NMDA receptor.
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65
Buspirone is an anxiolytic drug that acts by…

A) partial agonism of 5-HT₁A receptors.
B) positive modulation of GABAA receptors.
C) negative modulation of NMDA receptors.
D) antagonism of 5-HT₂C receptors.
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66
Combining a 5-HT₁A receptor antagonist with an SSRI would likely…

A) increase the risk of adverse effects.
B) shorten the response time for an anxiolytic effect.
C) improve anxiolytic effects but worsen depressive effects.
D) diminish an antidepressant's ability to reduce anxiety.
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67
The activation of presynaptic 5-HT₁A receptors causes…

A) a decrease in serotonin reuptake.
B) an increased release of serotonin from serotonin neurons.
C) an inhibition of serotonin neurons.
D) a positive feedback onto other serotonin neurons.
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68
In an elevated plus maze,anxiolytic-like effects are shown if a lab rat…

A) spends more time in the open arms than closed arms.
B) overall activity in the maze increases.
C) spends most of its time in the middle of the maze.
D) spends more time in the closed arms than open arms.
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69
For the treatment of obsessive compulsive disorder,antidepressant drugs…

A) are effective only when combined with an antipsychotic drug.
B) worsen OCD symptoms.
C) do not adequately reduce its symptoms.
D) require a longer treatment time than for other anxiety disorders.
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70
Antagonism of alpha2 adrenoceptor acting as heteroceptors on serotonin axon terminals will…

A) increase serotonin release.
B) decrease serotonin release.
C) increase norepinephrine release.
D) decrease norepinephrine release.
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71
The drug zolpidem (Ambien)is an example of a …

A) antihistamine.
B) barbiturate hypnotic.
C) benzodiazepine drug.
D) Z-drug.
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72
BZ II sites are found in the…

A) amygdala.
B) substantia nigra.
C) thalamus.
D) cerebellum.
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Unlock Deck
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73
The existence of benzodiazepine sites on GABAA receptors suggests that …

A) benzodiazepines are made naturally in plants.
B) there are chemical in the brain that bind to these sites.
C) the brain is naturally responsive to depressant drugs.
D) there are benzodiazepine sites on GABAB receptors.
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74
Approximately how many patients with anxiety disorder fail to respond adequately to antidepressant medications ?

A) one-eighth
B) one-third
C) half
D) three-fourth
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75
The first-line treatments for anxiety disorders are…

A) antidepressant drugs.
B) benzodiazepines.
C) barbiturates.
D) anticonvulsants.
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76
Extended release tablets have been developed for buspirone because…

A) buspirone acts too quickly for anxiolytic effects to occur.
B) buspirone otherwise degrades rapidly in the stomach.
C) users become impatient and fail to take subsequent administrations of the drug.
D) buspirone's active metabolites are ineffective for treating anxiety symptoms.
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77
Why might an anticonvulsant drug be effective for anxiety?

A) It exhibits neuroprotective effects.
B) It is a positive modulator for GABAA receptors.
C) It is an antagonist for NMDA receptors.
D) It is a partial agonist GABAA receptors.
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78
Approximately how much buspirone is broken down by enzymes in the stomach?

A) 10%
B) 25%
C) 45%
D) 90%
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79
Engaging in walking,driving,doing laundry,or eating while asleep are examples of …

A) drug-induced sleep walking.
B) subconscious behaviors.
C) hypnosis.
D) sleep-related complex behaviors.
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80
An increased risk of suicide when first taking an antidepressant drug may be due to…

A) onset of anxiety.
B) increase in adverse effects.
C) activation of presynaptic 5-HT₁A receptors.
D) blockage of serotonin membrane transporters.
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Unlock Deck
Unlock for access to all 114 flashcards in this deck.