Deck 52: Alterations in Musculoskeletal Function: Rheumatic Disorders

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Question
A clinical finding consistent with a diagnosis of rheumatoid arthritis would be

A) systemic manifestations of inflammation.
B) localized pain in weight-bearing joints.
C) reduced excretion of uric acid by the kidney.
D) firm, crystallized nodules or "tophi" at the affected joints.
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Question
To avoid the progression of cutaneous lesions,a patient diagnosed with systemic lupus erythematosus (SLE)should

A) avoid sun exposure.
B) avoid excessive use of moisturizers.
C) refrain from washing the affected areas.
D) apply warm, wet compresses daily.
Question
Ankylosing spondylitis is characterized by

A) inflammation, stiffness, and fusion of spinal joints.
B) loss of articular cartilage in weight-bearing joints.
C) excessive bone remodeling leading to soft bone.
D) immune mechanisms leading to widespread joint inflammation.
Question
Individuals diagnosed with systemic lupus erythematosus (SLE)are at risk for developing numerous complications of various organs because of

A) excessive production of connective tissue.
B) formation of osteophytes in tissues.
C) immune injury to basement membranes.
D) impaired tissue oxygen transport.
Question
Enteropathic arthritis is associated with

A) irritable bowel syndrome.
B) inflammatory bowel disease.
C) chronic constipation.
D) chronic diarrhea.
Question
Prosthetic joint infection is most often because of

A) defective replacement material.
B) injury to the joint.
C) hematogenous transfer.
D) arthritis.
Question
Although skin manifestations may occur in numerous locations,the classic presentation of systemic lupus erythematosus (SLE)includes

A) lesions affecting the palms of hands and the soles of feet.
B) dry, scaly patches in the antecubital area and behind the knees.
C) cracked, scaly areas in the webs of fingers.
D) a butterfly pattern rash on the face across the bridge of the nose.
Question
It is true that scleroderma involves

A) inflammation and fibrosis of connective tissue.
B) autoantibodies against acetylcholine receptors.
C) infection by beta-hemolytic streptococcus.
D) inflammation caused by antigenic fragments of dead organisms.
Question
Systemic lupus erythematosus (SLE)is a rheumatic disease attributed to

A) wear and tear on weight-bearing joints.
B) septic joint inflammation and necrosis.
C) unknown etiologic factors.
D) autoimmune mechanisms.
Question
In contrast to osteoarthritis,rheumatoid arthritis may be associated with

A) debilitating joint pain and stiffness.
B) improvement in symptoms with aspirin therapy.
C) changes in activities of daily living.
D) systemic aching in the musculoskeletal system.
Question
The pain of nonarticular rheumatism ("growing pain")is worse

A) during activity.
B) following strenuous exercise.
C) upon awakening.
D) during the night.
Question
Tophi are

A) renal calculi composed of uric acid.
B) deposits of urate crystals in tissues.
C) painful edematous joints.
D) spots that coalesce in a malar rash.
Question
Gouty arthritis is a complication of

A) group A streptococcal infection.
B) autoimmune destruction of joint collagen.
C) excessive production of urea.
D) inadequate renal excretion of uric acid.
Question
Rheumatoid arthritis involves joint inflammation caused by

A) bacterial infection.
B) trauma.
C) autoimmune injury.
D) congenital hypermobility.
Question
The earliest manifestation of scleroderma is

A) thick, tight, shiny skin.
B) skin hyper/hypopigmentation.
C) renal impairment.
D) Raynaud phenomenon.
Question
A laboratory test result that helps confirm the diagnosis of systemic lupus erythematosus (SLE)is

A) elevated serum calcium level.
B) elevated monoclonal antibody titer.
C) positive antinuclear antibodies.
D) positive microsomal antibodies.
Question
The most common presenting sign/symptom with rheumatic fever is

A) cardiac murmur.
B) polyarthritis.
C) rash.
D) painless nodules.
Question
Rheumatoid arthritis is commonly associated with the presence of rheumatoid factor autoantibodies in the bloodstream.This indicates that rheumatoid arthritis is likely to be

A) caused by bacterial infection.
B) an autoimmune process.
C) an infective process.
D) because of an enzymatic defect.
Question
Systemic disorders include

A) adhesive capsulitis.
B) verrucae.
C) osteoarthritis.
D) rheumatoid arthritis.
Question
The final stage of gout,characterized by crystalline deposits in cartilage,synovial membranes,and soft tissue,is called

A) tophaceous gout.
B) gouty arthritis.
C) complicated gout.
D) asymptomatic hyperuricemia.
Question
Characteristics of gout include (Select all that apply.)

A) disturbed uric acid metabolism.
B) crystalline deposits in bony and connective tissue.
C) onset before menopause in women.
D) cardiac involvement.
E) renal involvement.
Question
The chief pathologic features of osteoarthritis are

A) stress fractures of the epiphysis, inflammation of the diaphysis, and accumulation of excessive synovial fluid.
B) autoimmune damage to the synovium, destruction of articular cartilage by pannus, and thickening of synovial fluid.
C) degeneration of articular cartilage, destruction of the bone under the cartilage, and thickening of the synovium.
D) thinning of the joint capsule, resorption of bone, excessive formation of new bone, and formation of bone spurs.
Question
Manifestations of osteoarthritis include (Select all that apply.)

A) nodules on joints of the hands.
B) crepitus with joint movement.
C) pain that is worse upon arising in the morning.
D) stiffness that worsens with joint use.
E) narrowing of joint spaces.
Question
The pathophysiology of rheumatoid arthritis involves

A) immune cells accumulating in pannus and destroying articular cartilage.
B) free radicals attaching to the synovial membrane and tunneling into articular cartilage.
C) excessive wear and tear and microtrauma that damage articular cartilage.
D) cysts developing in subchondral bone and creating fissures in articular cartilage.
Question
"Tell me again the name of that chemical that makes crystals when my gout flares up," asks the client.The nurse's best response is

A) calcium phosphate.
B) urea.
C) uric acid.
D) beta-hydroxybutyric acid.
Question
Ankylosing spondylitis causes

A) intervertebral joint fusion.
B) instability of synovial joints.
C) costal cartilage degeneration.
D) temporomandibular joint degeneration.
Question
Signs/symptoms of Lyme disease include (Select all that apply.)

A) fever and chills.
B) migratory rash.
C) arthritic pain.
D) headache.
E) myalgia.
Question
"Please explain the pathophysiology of osteoarthritis to me," says another nurse."Is it just wear and tear so that the cartilage wears out?" Your best response is

A) "Yes; repeated use just wears out the cartilage, until it becomes thin and denuded. That causes pain and will eventually cause joint inflammation."
B) "Yes; with increasing age, the inflammation from repeated joint use accumulates and causes the cartilage to get thin and ragged until it disappears."
C) "No; cells in bone, cartilage, and the synovial membrane all get activated and secrete inflammatory mediators that destroy cartilage and damage bone."
D) "No; autoimmune cells infiltrate the joint and collect on the cartilage in a mass called 'pannus' that eventually thins and destroys the cartilage."
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Deck 52: Alterations in Musculoskeletal Function: Rheumatic Disorders
1
A clinical finding consistent with a diagnosis of rheumatoid arthritis would be

A) systemic manifestations of inflammation.
B) localized pain in weight-bearing joints.
C) reduced excretion of uric acid by the kidney.
D) firm, crystallized nodules or "tophi" at the affected joints.
systemic manifestations of inflammation.
2
To avoid the progression of cutaneous lesions,a patient diagnosed with systemic lupus erythematosus (SLE)should

A) avoid sun exposure.
B) avoid excessive use of moisturizers.
C) refrain from washing the affected areas.
D) apply warm, wet compresses daily.
avoid sun exposure.
3
Ankylosing spondylitis is characterized by

A) inflammation, stiffness, and fusion of spinal joints.
B) loss of articular cartilage in weight-bearing joints.
C) excessive bone remodeling leading to soft bone.
D) immune mechanisms leading to widespread joint inflammation.
inflammation, stiffness, and fusion of spinal joints.
4
Individuals diagnosed with systemic lupus erythematosus (SLE)are at risk for developing numerous complications of various organs because of

A) excessive production of connective tissue.
B) formation of osteophytes in tissues.
C) immune injury to basement membranes.
D) impaired tissue oxygen transport.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
5
Enteropathic arthritis is associated with

A) irritable bowel syndrome.
B) inflammatory bowel disease.
C) chronic constipation.
D) chronic diarrhea.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
6
Prosthetic joint infection is most often because of

A) defective replacement material.
B) injury to the joint.
C) hematogenous transfer.
D) arthritis.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
7
Although skin manifestations may occur in numerous locations,the classic presentation of systemic lupus erythematosus (SLE)includes

A) lesions affecting the palms of hands and the soles of feet.
B) dry, scaly patches in the antecubital area and behind the knees.
C) cracked, scaly areas in the webs of fingers.
D) a butterfly pattern rash on the face across the bridge of the nose.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
8
It is true that scleroderma involves

A) inflammation and fibrosis of connective tissue.
B) autoantibodies against acetylcholine receptors.
C) infection by beta-hemolytic streptococcus.
D) inflammation caused by antigenic fragments of dead organisms.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
9
Systemic lupus erythematosus (SLE)is a rheumatic disease attributed to

A) wear and tear on weight-bearing joints.
B) septic joint inflammation and necrosis.
C) unknown etiologic factors.
D) autoimmune mechanisms.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
10
In contrast to osteoarthritis,rheumatoid arthritis may be associated with

A) debilitating joint pain and stiffness.
B) improvement in symptoms with aspirin therapy.
C) changes in activities of daily living.
D) systemic aching in the musculoskeletal system.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
11
The pain of nonarticular rheumatism ("growing pain")is worse

A) during activity.
B) following strenuous exercise.
C) upon awakening.
D) during the night.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
12
Tophi are

A) renal calculi composed of uric acid.
B) deposits of urate crystals in tissues.
C) painful edematous joints.
D) spots that coalesce in a malar rash.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
13
Gouty arthritis is a complication of

A) group A streptococcal infection.
B) autoimmune destruction of joint collagen.
C) excessive production of urea.
D) inadequate renal excretion of uric acid.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
14
Rheumatoid arthritis involves joint inflammation caused by

A) bacterial infection.
B) trauma.
C) autoimmune injury.
D) congenital hypermobility.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
15
The earliest manifestation of scleroderma is

A) thick, tight, shiny skin.
B) skin hyper/hypopigmentation.
C) renal impairment.
D) Raynaud phenomenon.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
16
A laboratory test result that helps confirm the diagnosis of systemic lupus erythematosus (SLE)is

A) elevated serum calcium level.
B) elevated monoclonal antibody titer.
C) positive antinuclear antibodies.
D) positive microsomal antibodies.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
17
The most common presenting sign/symptom with rheumatic fever is

A) cardiac murmur.
B) polyarthritis.
C) rash.
D) painless nodules.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
18
Rheumatoid arthritis is commonly associated with the presence of rheumatoid factor autoantibodies in the bloodstream.This indicates that rheumatoid arthritis is likely to be

A) caused by bacterial infection.
B) an autoimmune process.
C) an infective process.
D) because of an enzymatic defect.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
19
Systemic disorders include

A) adhesive capsulitis.
B) verrucae.
C) osteoarthritis.
D) rheumatoid arthritis.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
20
The final stage of gout,characterized by crystalline deposits in cartilage,synovial membranes,and soft tissue,is called

A) tophaceous gout.
B) gouty arthritis.
C) complicated gout.
D) asymptomatic hyperuricemia.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
21
Characteristics of gout include (Select all that apply.)

A) disturbed uric acid metabolism.
B) crystalline deposits in bony and connective tissue.
C) onset before menopause in women.
D) cardiac involvement.
E) renal involvement.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
22
The chief pathologic features of osteoarthritis are

A) stress fractures of the epiphysis, inflammation of the diaphysis, and accumulation of excessive synovial fluid.
B) autoimmune damage to the synovium, destruction of articular cartilage by pannus, and thickening of synovial fluid.
C) degeneration of articular cartilage, destruction of the bone under the cartilage, and thickening of the synovium.
D) thinning of the joint capsule, resorption of bone, excessive formation of new bone, and formation of bone spurs.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
23
Manifestations of osteoarthritis include (Select all that apply.)

A) nodules on joints of the hands.
B) crepitus with joint movement.
C) pain that is worse upon arising in the morning.
D) stiffness that worsens with joint use.
E) narrowing of joint spaces.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
24
The pathophysiology of rheumatoid arthritis involves

A) immune cells accumulating in pannus and destroying articular cartilage.
B) free radicals attaching to the synovial membrane and tunneling into articular cartilage.
C) excessive wear and tear and microtrauma that damage articular cartilage.
D) cysts developing in subchondral bone and creating fissures in articular cartilage.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
25
"Tell me again the name of that chemical that makes crystals when my gout flares up," asks the client.The nurse's best response is

A) calcium phosphate.
B) urea.
C) uric acid.
D) beta-hydroxybutyric acid.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
26
Ankylosing spondylitis causes

A) intervertebral joint fusion.
B) instability of synovial joints.
C) costal cartilage degeneration.
D) temporomandibular joint degeneration.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
27
Signs/symptoms of Lyme disease include (Select all that apply.)

A) fever and chills.
B) migratory rash.
C) arthritic pain.
D) headache.
E) myalgia.
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
28
"Please explain the pathophysiology of osteoarthritis to me," says another nurse."Is it just wear and tear so that the cartilage wears out?" Your best response is

A) "Yes; repeated use just wears out the cartilage, until it becomes thin and denuded. That causes pain and will eventually cause joint inflammation."
B) "Yes; with increasing age, the inflammation from repeated joint use accumulates and causes the cartilage to get thin and ragged until it disappears."
C) "No; cells in bone, cartilage, and the synovial membrane all get activated and secrete inflammatory mediators that destroy cartilage and damage bone."
D) "No; autoimmune cells infiltrate the joint and collect on the cartilage in a mass called 'pannus' that eventually thins and destroys the cartilage."
Unlock Deck
Unlock for access to all 28 flashcards in this deck.
Unlock Deck
k this deck
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Unlock Deck
Unlock for access to all 28 flashcards in this deck.