Deck 20: Toxoplasmosis

Question 1

Major sources of increasing human infection with T.gondii include all the following except:

A) fecal contamination of food with the T.gondii organism.
B) infected meat.
C) bloody body fluids.
D) raw infected milk.

Answer 1

bloody body fluids.

Question 2

The preferred method for detection of T.gondii is:

A) culture.
B) ELISA.
C) IFA.
D) PCR.

Answer 2

ELISA.

Question 3

The best evidence of toxoplasmosis infection is a significant change in:

A) two appropriately timed specimens.
B) acute and convalescent specimens.
C) two appropriate specimens analyzed at the same time in the laboratory.
D) all of the above.

Answer 3

all of the above.

Question 4

Transfusion-transmitted toxoplasmosis is associated with:

A) packed red blood cells.
B) platelet concentrates.
C) leukocyte concentrates.
D) either b or c

Question 5

Symptoms of acquired T.gondii infection can:

A) be mild.
B) resemble infectious mononucleosis.
C) cause a urinary tract infection.
D) both a and b

Question 6

The avidity result is determined using:

A) ratios of antibody titration curves of urea-treated and untreated sera.
B) titers of antibody in preinfection and postinfection specimens.
C) amniotic fluid versus serum.
D) both b and c

Question 7

Any positive result in a pregnant patient confirmed as positive by a second reference laboratory should be evaluated by:

A) amniocentesis testing by PCR for T.gondii.
B) IgM,IgA,and IgE ELISAs.
C) Sabin-Feldman dye test (IgG).
D) IgE immunosorbent agglutination assay.

Question 8

Toxoplasma-infected mothers who are not treated can give birth to a(n):

A) less than term infant.
B) underweight infant.
C) congenitally infected infant.
D) normal,healthy infant.

Question 9

All mammals can transmit T.gondii by:

A) casual contact.
B) transplacental transmission.
C) sexual contact.
D) none of the above.

Question 10

The definitive host of Toxoplasma gondii is the:

A) dog.
B) house cat.
C) chicken.
D) rodent class.

Question 11

IgM antibodies to T.gondii in an adult are an indication of:

A) current or recent infection.
B) chronic infection.
C) past infection.
D) antibody transmitted from another person.

Question 12

The PCR assay for T.gondii can be performed on:

A) serum or plasma.
B) fresh or frozen biopsy tissue.
C) cerebrospinal fluid.
D) all of the above.

Question 13

After IgM-positive sera undergo confirmatory testing,the results are interpreted as a(n):

A) recently acquired infection.
B) infection acquired in the past.
C) false-positive test result.
D) all of the above.

Question 14

The Centers for Disease Control and Prevention (CDC)suggests that any confirmed equivocal or ____________ test results for toxoplasmosis should be retested using a different assay.

A) positive
B) negative
C) questionable
D) prenatal

Question 15

Congenital toxoplasmosis can result in:

A) central nervous system (CNS)malformation.
B) prenatal mortality.
C) congenital heart defects.
D) both a and b

Question 16

Toxoplasma gondii antibody assay can demonstrate antibodies within __________ after infection.

A) 2 days
B) 1 week
C) 2 weeks
D) 1 month