Deck 12: Anabolism: the Use of Energy in Biosynthesis
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Deck 12: Anabolism: the Use of Energy in Biosynthesis
1
Different proteins have different amino acid __________.
sequences
2
Bacteria can synthesize unsaturated fatty acids only under anaerobic conditions.
False
3
Photoautotrophs are the only organisms that can incorporate (fix)carbon dioxide into biomolecules.
False
4
There are __________ common amino acids used to synthesize proteins.
A)20
B)61
C)64
D)25
A)20
B)61
C)64
D)25
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5
Assemblies of macromolecules are referred to as __________ complexes.
A)ultramolecular
B)supramolecular
C)metamolecular
D)maximolecular
A)ultramolecular
B)supramolecular
C)metamolecular
D)maximolecular
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6
Nitrogen fixation is used to form ATP,which is then used for energy reserves.
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7
In the synthesis of amino acids the addition of the amino nitrogen usually occurs __________ the synthesis of the carbon skeletons.
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8
Because peptidoglycan lies outside the plasma membrane,all steps in the complex synthesis process of this molecule takes place outside the cell.
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9
Large numbers of small monomeric molecules join together to form large molecules that are known as ______.
A)multimers
B)polymolecules
C)macromolecules
D)maximolecules
A)multimers
B)polymolecules
C)macromolecules
D)maximolecules
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10
Large structures (e.g.,ribosomes)form spontaneously from their macromolecular components by a process known as _____-_____.
or
or
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11
The use of compartmentation for the simultaneous but independent regulation of anabolic and catabolic pathways occurs generally in eukaryotes but not in prokaryotes.
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12
Although most autotrophic microorganisms fix carbon dioxide using the Calvin-Benson cycle,this pathway is absent in the Archaea.
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13
Unsaturated fatty acids are those containing carbon-carbon ________ bonds.
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14
Many enzyme catalyzed reactions are freely reversible; however,some key steps require separate enzymes for the reverse step in order to provide for independent regulation of anabolic and catabolic pathways.
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15
In the biosynthesis of nucleotides,pyrimidines are assembled starting with ribose-5-phosphate while ribose-5-phosphate is added after synthesis of the nitrogenous base for purines.
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16
Nongrowing cells continuously degrade and resynthesize cellular molecules during a process known as cellular turnover.
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17
Anabolic and catabolic pathways use different cofactors for similar reactions.
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18
Eukaryotic cells compartmentalize some anabolic and catabolic pathways so that these pathways can be operated _______.
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19
Synthesis of complex molecules from simpler ones with the input of energy is called ______.
A)metabolism
B)anabolism
C)catabolism
D)amphibolism
A)metabolism
B)anabolism
C)catabolism
D)amphibolism
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20
Which of the following is true about the synthesis of macromolecules from monomeric subunits?
A)It saves genetic storage capacity
B)It saves biosynthetic raw materials
C)It saves energy
D)All of the choices are correct.
A)It saves genetic storage capacity
B)It saves biosynthetic raw materials
C)It saves energy
D)All of the choices are correct.
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21
__________ reactions are used to replace TCA cycle intermediates that have been used to provide carbon skeletons for amino acid biosynthesis.
A)Amphibolic
B)Anaplerotic
C)Anabolic
D)Catabolic
A)Amphibolic
B)Anaplerotic
C)Anabolic
D)Catabolic
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22
A series of enzymatic steps that fixes carbon dioxide into carbohydrate is called the ______.
A)Pentose phosphate pathway
B)Embden-Meyerhoff pathway
C)Calvin-Benson cycle
D)Entner-Doudoroff pathway
A)Pentose phosphate pathway
B)Embden-Meyerhoff pathway
C)Calvin-Benson cycle
D)Entner-Doudoroff pathway
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23
Which pathway(s)is used to fix carbon dioxide?
A)Glycolysis
B)Reductive tricarboxylic pathway
C)Entner-Doudoroff
D)Pentose phosphate pathway
A)Glycolysis
B)Reductive tricarboxylic pathway
C)Entner-Doudoroff
D)Pentose phosphate pathway
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24
In order to synthesize new peptidoglycan for bacterial cell walls,the existing walls must be partially digested by __________ to provide acceptor ends for the new synthesis.
A)lysozyme
B)autolysins
C)autozymogens
D)peptidoglycolysins
A)lysozyme
B)autolysins
C)autozymogens
D)peptidoglycolysins
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25
The process of carbon dioxide fixation refers to
A)release of carbon dioxide during catabolic reactions.
B)reduction of carbon dioxide and incorporation into organic molecules that are assimilated.
C)release of carbon dioxide during anabolic reactions.
D)reaction of carbon dioxide with water to form carbonic acid.
A)release of carbon dioxide during catabolic reactions.
B)reduction of carbon dioxide and incorporation into organic molecules that are assimilated.
C)release of carbon dioxide during anabolic reactions.
D)reaction of carbon dioxide with water to form carbonic acid.
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26
The reduction of sulfate as a terminal electron acceptor during anaerobic respiration is called __________ sulfate reduction.
A)assimilatory
B)dissimilatory
C)amodulatory
D)demodulatory
A)assimilatory
B)dissimilatory
C)amodulatory
D)demodulatory
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27
Which of the following is a source of carbon skeletons that are used in the synthesis of amino acids?
A)Acetyl-CoA
B)TCA cycle intermediates
C)Glycolysis intermediates
D)All of the choices are correct.
A)Acetyl-CoA
B)TCA cycle intermediates
C)Glycolysis intermediates
D)All of the choices are correct.
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28
The synthesis of glucose from non-carbohydrate precursors is called ______.
A)glycolysis
B)glutamine synthase
C)gluconeogenesis
D)None of the choices are correct.
A)glycolysis
B)glutamine synthase
C)gluconeogenesis
D)None of the choices are correct.
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29
In order to form a single molecule of glucose,it takes ______ turns through the reactions of the Calvin-Benson cycle.
A)3
B)4
C)6
D)12
A)3
B)4
C)6
D)12
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30
Photoautotrophs use light energy directly for
A)the production of ATP and NADPH.
B)the reduction of carbon dioxide to glucose.
C)both the production of ATP and NADPH and the reduction of carbon dioxide to glucose.
D)neither the production of ATP and NADPH nor the reduction of carbon dioxide to glucose.
A)the production of ATP and NADPH.
B)the reduction of carbon dioxide to glucose.
C)both the production of ATP and NADPH and the reduction of carbon dioxide to glucose.
D)neither the production of ATP and NADPH nor the reduction of carbon dioxide to glucose.
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31
The photosynthetic production of one molecule of glucose requires __________ molecule(s)of ATP.
A)6
B)12
C)18
D)24
A)6
B)12
C)18
D)24
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32
Which of the following is not a phase of the Calvin-Benson Cycle?
A)Carboxylation phase
B)Oxidation phase
C)Reduction phase
D)Regeneration phase
A)Carboxylation phase
B)Oxidation phase
C)Reduction phase
D)Regeneration phase
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33
The reduction of sulfate for use in the production of compounds such as cysteine is called __________ sulfate reduction.
A)assimilatory
B)dissimilatory
C)amodulatory
D)demodulatory
A)assimilatory
B)dissimilatory
C)amodulatory
D)demodulatory
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34
Symbiotic nitrogen fixation can consume up to ______% of the ATP generated by the host plant.
A)5
B)20
C)30
D)50
A)5
B)20
C)30
D)50
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35
__________ is the carrier molecule required to transport peptidoglycan subunits to the location where they will be incorporated into the growing bacterial cell wall.
A)Bactoprenol
B)UDP glucose
C)Acyl carrier protein
D)Malonyl-CoA
A)Bactoprenol
B)UDP glucose
C)Acyl carrier protein
D)Malonyl-CoA
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36
Which pathway(s)are used by eukaryotic microorganisms to fix carbon dioxide?
A)Calvin-Benson cycle
B)Reductive tricarboxylic pathway
C)Entner-Doudoroff
D)None of the choices are correct.
A)Calvin-Benson cycle
B)Reductive tricarboxylic pathway
C)Entner-Doudoroff
D)None of the choices are correct.
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37
Most microorganisms assimilate nitrogen as ______.
A)nitrite
B)hydrazine
C)nitrate
D)N2
A)nitrite
B)hydrazine
C)nitrate
D)N2
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38
Microorganisms assimilate large amounts of all of the following except ______ into organic molecules.
A)nitrogen
B)phosphorus
C)sodium
D)sulfur
A)nitrogen
B)phosphorus
C)sodium
D)sulfur
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39
The major reductive amination pathway for incorporation of nitrogen into amino acids initially involves the production of __________ from alpha-ketoglutarate.
A)tryptophan
B)cysteine
C)arginine
D)glutamate
A)tryptophan
B)cysteine
C)arginine
D)glutamate
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40
The photosynthetic production of one molecule of glucose requires __________ molecule(s)of NADPH.
A)6
B)12
C)18
D)24
A)6
B)12
C)18
D)24
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41
Nitrogen fixation depends on the enzyme nitrogenase,which is produced by some ______.
A)Archaea
B)bacteria
C)eukaryotes
D)bacteria and Archaea but no eukaryotes
E)fungi and bacteria
A)Archaea
B)bacteria
C)eukaryotes
D)bacteria and Archaea but no eukaryotes
E)fungi and bacteria
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42
The use of pyruvate carboxylase to convert pyruvate into oxaloacetate is a step unique to gluconeogenesis compared to the Embden-Meyerhof pathway.
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43
How many enzyme pathways are shared between gluconeogenesis and the Embden-Meyerhof pathway?
A)3
B)6
C)8
D)11
A)3
B)6
C)8
D)11
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44
Which of the following is not generally true about fatty acids produced by microorganisms?
A)Fatty acids are monocarboxylic acids.
B)Fatty acids have long alkyl chains.
C)Gram-positive bacteria often make cyclopropane fatty acids.
D)All of the choices are correct.
A)Fatty acids are monocarboxylic acids.
B)Fatty acids have long alkyl chains.
C)Gram-positive bacteria often make cyclopropane fatty acids.
D)All of the choices are correct.
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45
A purine or pyrimidine that is attached to a sugar,either ribose or deoxyribose,is called a _______.
A)nucleotide
B)nucleoside
C)nitrogenous base
D)nucleic acid
A)nucleotide
B)nucleoside
C)nitrogenous base
D)nucleic acid
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46
A _____ _____,such as UDPG,is often attached to many sugars during synthesis.
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47
Which of the following cofactors is very important in the synthesis of purines?
A)Acetyl-CoA
B)Cytidine diphosphate
C)Folic acid
D)Glutathione
A)Acetyl-CoA
B)Cytidine diphosphate
C)Folic acid
D)Glutathione
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48
The reduction of atmospheric nitrogen to ammonia is called _______.
A)ammonification
B)nitrification
C)denitrification
D)nitrogen fixation
A)ammonification
B)nitrification
C)denitrification
D)nitrogen fixation
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49
Which of the following has the phases of the Calvin-Benson cycle in the correct order,starting with the entry of ribulose 1,5-bisphosphate?
A)Regeneration phase,carboxylation phase,reduction phase
B)Reduction phase,carboxylation phase,regeneration phase
C)Carboxylation phase,regeneration phase,reduction phase
D)Carboxylation phase,reduction phase,regeneration phase
A)Regeneration phase,carboxylation phase,reduction phase
B)Reduction phase,carboxylation phase,regeneration phase
C)Carboxylation phase,regeneration phase,reduction phase
D)Carboxylation phase,reduction phase,regeneration phase
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50
A purine or pyrimidine that is attached to a sugar,either ribose or deoxyribose,which is attached to one or more phosphate groups is called a _______.
A)nucleotide
B)nucleoside
C)nitrogenous base
D)nucleic acid
A)nucleotide
B)nucleoside
C)nitrogenous base
D)nucleic acid
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51
Which of the following do(es)not contribute to the construction of membrane phospholipids?
A)Glycolysis
B)Fatty acid biosynthesis
C)Amino acid biosynthesis
D)Nucleotide biosynthesis
A)Glycolysis
B)Fatty acid biosynthesis
C)Amino acid biosynthesis
D)Nucleotide biosynthesis
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52
Assimilation of organic phosphates from the surroundings uses enzymes known as ______.
A)phosphorylases
B)phosphatases
C)phosphosynthetases
D)phosphoisomerases
A)phosphorylases
B)phosphatases
C)phosphosynthetases
D)phosphoisomerases
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53
__________ are cyclic nitrogenous bases with two rings and pronounced aromatic properties.
A)Purines
B)Quinones
C)Amino acids
D)Fatty acids
A)Purines
B)Quinones
C)Amino acids
D)Fatty acids
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54
Many microbes use pyruvate carboxylase or phosphoenolpyruvate carboxylase to
A)to synthesize amino acids.
B)to synthesize glucose.
C)to synthesize oxaloacetate.
D)to synthesize acetyl-CoA.
A)to synthesize amino acids.
B)to synthesize glucose.
C)to synthesize oxaloacetate.
D)to synthesize acetyl-CoA.
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55
Which of the following is the best description of a precursor metabolite?
A)An intermediate in the formation of cursor metabolites
B)A macromolecule consumed in the first steps of metabolism
C)An enzyme that is reduced in a metabolic reaction
D)A carbon skeleton used as a starting substrate
A)An intermediate in the formation of cursor metabolites
B)A macromolecule consumed in the first steps of metabolism
C)An enzyme that is reduced in a metabolic reaction
D)A carbon skeleton used as a starting substrate
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56
Phosphorous is usually assimilated by microorganisms as ______.
A)polyphosphate (volutin)
B)phosphene
C)elemental phosphate (Po)
D)phosphate
A)polyphosphate (volutin)
B)phosphene
C)elemental phosphate (Po)
D)phosphate
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57
An autotroph is likely to convert CO2 into reduced organic carbon in order to produce precursor metabolites.
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58
Purines and pyrimidines are precursors for synthesis of _______.
A)fatty acids
B)nucleic acids
C)proteins
D)peptidoglycan
A)fatty acids
B)nucleic acids
C)proteins
D)peptidoglycan
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59
In bacteria,synthesis of long chain polysaccharides,such as starch and glycogen,have glucose donated to the end of the growing chain by _____.
A)ADP-glucose
B)ATP-mannose
C)UDPG
D)UTP-galactose
A)ADP-glucose
B)ATP-mannose
C)UDPG
D)UTP-galactose
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60
Unsaturated fatty acids are those containing __________ carbon-carbon double bond(s).
A)only one
B)exactly two
C)one or more
D)two or more
A)only one
B)exactly two
C)one or more
D)two or more
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61
A pyrimidine or purine base that has been joined with a ribose or deoxyribose sugar moiety is now termed a _____.
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62
Bacterial peptidoglycan is not a good target for antibiotics because it is present in human cells as well,leading to host damage.
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63
The bacterial cell wall component,_____,is a long,polypeptide chain of NAM and NAG residues that provide the bacterial cell protection from lysis.
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64
Purine bases,such as adenine and guanine,have ring(s)in their structure.
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65
Bacteria synthesize CDP-diacylglycerol in order to build _____,a major cell membrane phospholipid component.
A)phosphatidylethanolamine
B)lipid rafts
C)lipopolysaccharide
D)peptidoglycan
A)phosphatidylethanolamine
B)lipid rafts
C)lipopolysaccharide
D)peptidoglycan
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66
Lipopolysaccharide is comprised of three moieties (lipid A,core oligosaccharide,and O-antigen),which require _____ biosynthetic pathway(s).
A)one
B)two
C)three
D)six
A)one
B)two
C)three
D)six
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67
The synthesis of _____,a component of Gram-negative bacterial outer membranes,is complex because it requires understanding both carbohydrate and lipid biosynthesis pathways.
or
or
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68
In the biosynthesis of glycerol,the reduction of dihydroxyacetone phosphate produces what important precursor molecule?
A)Dihydrogen monoxide
B)Glycerol-3-phosphate
C)Coenzyme A
D)Phospholipids
A)Dihydrogen monoxide
B)Glycerol-3-phosphate
C)Coenzyme A
D)Phospholipids
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69
The -jelly roll of the Lpt system functions to
A)help hide lipid A from the hydrophilic periplasm during LPS transport to the membrane.
B)help attach the O-antigen to core oligosaccharide moieties during synthesis of LPS.
C)help anchor the newly positioned LPS on the bacterial cell surface.
D)help translocate assembled LPS across the outer membrane of the bacterial cell.
A)help hide lipid A from the hydrophilic periplasm during LPS transport to the membrane.
B)help attach the O-antigen to core oligosaccharide moieties during synthesis of LPS.
C)help anchor the newly positioned LPS on the bacterial cell surface.
D)help translocate assembled LPS across the outer membrane of the bacterial cell.
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70
Two intermediates of the sterol biosynthesis pathway,isopentenyl diphosphate and dimethylallyl diphosphate,are used by archaea in the biosynthesis of _____.
A)diacylglycerol
B)hormones
C)nucleotides
D)isoprenoids
A)diacylglycerol
B)hormones
C)nucleotides
D)isoprenoids
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71
Cells save energy and materials by using many of the same enzymes for both .
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72
Which statement regarding porphyrin synthesis pathways is CORRECT?
A)The glutamate porphyrin pathway is used by all non-photosynthetic eukaryotes and alpha-proteobacteria.
B)There is very little conservation of porphyrin synthesis pathways between eukaryotes,bacteria,and archaea.
C)The porphyrin biosynthetic pathways are unified at the step of 5-aminolevulinic acid.
D)The succinyl-CoA/glycine porphyrin pathway is used by all bacteria,photosynthetic eukaryotes,and archaea.
A)The glutamate porphyrin pathway is used by all non-photosynthetic eukaryotes and alpha-proteobacteria.
B)There is very little conservation of porphyrin synthesis pathways between eukaryotes,bacteria,and archaea.
C)The porphyrin biosynthetic pathways are unified at the step of 5-aminolevulinic acid.
D)The succinyl-CoA/glycine porphyrin pathway is used by all bacteria,photosynthetic eukaryotes,and archaea.
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73
To convert a nucleoside into a nucleotide,what moiety must be added?
A)One or more purine bases
B)One or more double bonds
C)One or more pyrimidine bases
D)One or more phosphate groups
A)One or more purine bases
B)One or more double bonds
C)One or more pyrimidine bases
D)One or more phosphate groups
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74
In bacterial synthesis of polysaccharides,such as starch and glycogen,glucose is donated to the end of the growing chain by ADP-glucose.A similar reaction occurs in bacterial branching of phospholipids when phosphatidic acid is attached to a _____.
A)fatty acyl-ATP
B)acetyl-CoA
C)dihydroxyacetone phosphate
D)cytidine diphosphate carrier
A)fatty acyl-ATP
B)acetyl-CoA
C)dihydroxyacetone phosphate
D)cytidine diphosphate carrier
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75
Which of the following molecules is not considered a porphyrin?
A)Chlorophyll
B)Vitamin B12
C)Hemoglobin
D)Peptidoglycan
A)Chlorophyll
B)Vitamin B12
C)Hemoglobin
D)Peptidoglycan
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76
The cyclic nitrogenous base used in transcription,uracil,is a _____.
A)protein
B)pyrimidine
C)purine
D)porphyrin
A)protein
B)pyrimidine
C)purine
D)porphyrin
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77
Because bacterial LPS is both hydrophilic and hydrophobic,a specialized transporting system,_____,is required for membrane transport and insertion.
A)Lpt
B)cytidine diphosphate carrier protein
C)Tol
D)acyl-carrier protein
A)Lpt
B)cytidine diphosphate carrier protein
C)Tol
D)acyl-carrier protein
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78
Eukaryotic cell membranes use many sterol molecules for construction,which contrasts with archaeal membranes that utilize _____.
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