Deck 18: Metabolic Pathways and Energy Production
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Deck 18: Metabolic Pathways and Energy Production
1
The initial stage of the digestion of protein is catalyzed by an enzyme called ________.
A)chymotrypsin
B)peptidase
C)pepsin
D)amylase
E)trypsin
A)chymotrypsin
B)peptidase
C)pepsin
D)amylase
E)trypsin
pepsin
2
Digestion of carbohydrates begins in the ________.
A)mouth
B)stomach
C)pancreas
D)small intestine
E)large intestine
A)mouth
B)stomach
C)pancreas
D)small intestine
E)large intestine
mouth
3
The first stage of catabolism is ________.
A)the citric acid cycle
B)production of pyruvate
C)production of acetyl-CoA
D)buildup of macromolecules from monomers
E)digestion of large molecules
A)the citric acid cycle
B)production of pyruvate
C)production of acetyl-CoA
D)buildup of macromolecules from monomers
E)digestion of large molecules
digestion of large molecules
4
The components of ATP are ________.
A)adenosine,ribose,and three phosphate groups
B)aniline and three phosphate groups
C)alanine,ribose,and three phosphate groups
D)adenine,ribose,and three phosphate groups
E)adenosine,deoxyribose,and three phosphate groups
A)adenosine,ribose,and three phosphate groups
B)aniline and three phosphate groups
C)alanine,ribose,and three phosphate groups
D)adenine,ribose,and three phosphate groups
E)adenosine,deoxyribose,and three phosphate groups
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5
How many main stages of catabolism are there?
A)one
B)two
C)three
D)four
E)five
A)one
B)two
C)three
D)four
E)five
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6
The citric acid cycle takes place in the ________.
A)mitochondria
B)cytosol
C)cytoplasm
D)Golgi apparatus
E)endoplasmic reticulum
A)mitochondria
B)cytosol
C)cytoplasm
D)Golgi apparatus
E)endoplasmic reticulum
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7
The hydrolysis of ATP to ADP is ________.
A)endothermic
B)exothermic
C)isothermic
D)an oxidation
E)a reduction
A)endothermic
B)exothermic
C)isothermic
D)an oxidation
E)a reduction
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8
The middle stage of catabolism is the point at which ________.
A)acetyl-CoA is produced
B)monomers are produced from macromolecules
C)macromolecules are made from monomers
D)glycogen is converted to glucose
E)excess nutrients are stored as fats
A)acetyl-CoA is produced
B)monomers are produced from macromolecules
C)macromolecules are made from monomers
D)glycogen is converted to glucose
E)excess nutrients are stored as fats
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9
The digestion of protein begins in the ________.
A)mouth
B)stomach
C)small intestine
D)large intestine
E)pancreas
A)mouth
B)stomach
C)small intestine
D)large intestine
E)pancreas
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10
An enzyme that can facilitate the breakdown of amylose into smaller units is ________.
A)glucose phosphatase
B)alcohol dehydrogenase
C)amylase
D)lactase
E)maltase
A)glucose phosphatase
B)alcohol dehydrogenase
C)amylase
D)lactase
E)maltase
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11
The reactions by which complex molecules are built up for the body's use are ________.
A)transmission reactions
B)catabolic reactions
C)anabolic reactions
D)glucogenesis
E)gluconeogenesis
A)transmission reactions
B)catabolic reactions
C)anabolic reactions
D)glucogenesis
E)gluconeogenesis
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12
The reactions by which complex molecules are broken down into simpler ones for the body's use are ________.
A)transmission reactions
B)catabolic reactions
C)anabolic reactions
D)glucogenesis
E)gluconeogenesis
A)transmission reactions
B)catabolic reactions
C)anabolic reactions
D)glucogenesis
E)gluconeogenesis
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13
Overall,catabolic reactions ________.
A)release energy
B)take in energy
C)occur mainly in the liver
D)occur outside the cell membrane
E)take place in the nucleus of the cell
A)release energy
B)take in energy
C)occur mainly in the liver
D)occur outside the cell membrane
E)take place in the nucleus of the cell
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14
Which of the three major stages of metabolism includes the citric acid cycle?
A)stage one
B)stage two
C)stage three
A)stage one
B)stage two
C)stage three
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15
The main compound used to release energy for metabolism is ________.
A)sucrose
B)glucose phosphate
C)adenosine triphosphate
D)ribonucleic acid
E)NAD+
A)sucrose
B)glucose phosphate
C)adenosine triphosphate
D)ribonucleic acid
E)NAD+
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16
The digestion of fats begins when the fat globules are ________.
A)emulsified by bile salts
B)attacked by protease enzymes to form smaller fat globules
C)converted to lipoproteins for greater solubility
D)hydrolyzed to glucose and amino acids
E)hydrolyzed to glycerol and fatty acids
A)emulsified by bile salts
B)attacked by protease enzymes to form smaller fat globules
C)converted to lipoproteins for greater solubility
D)hydrolyzed to glucose and amino acids
E)hydrolyzed to glycerol and fatty acids
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17
The final products of catabolic reactions are ________.
A)carbon dioxide,water,and ammonia
B)glucose,lipids,and glycogen
C)lipids,oxygen,and water
D)RNA and DNA
E)lipids and carbohydrates
A)carbon dioxide,water,and ammonia
B)glucose,lipids,and glycogen
C)lipids,oxygen,and water
D)RNA and DNA
E)lipids and carbohydrates
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18
Anabolic reactions are reactions that ________.
A)use oxidation but not reduction
B)break down large molecules into smaller ones
C)take place in the mitochondria
D)require energy
E)give off energy
A)use oxidation but not reduction
B)break down large molecules into smaller ones
C)take place in the mitochondria
D)require energy
E)give off energy
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19
The digestion of fats begins in the ________.
A)mouth
B)stomach
C)small intestine
D)gall bladder
E)large intestine
A)mouth
B)stomach
C)small intestine
D)gall bladder
E)large intestine
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20
Protein synthesis takes place ________.
A)in the mitochondria
B)on the endoplasmic reticulum
C)in the nucleus
D)on the ribosomes
E)in the cytosol
A)in the mitochondria
B)on the endoplasmic reticulum
C)in the nucleus
D)on the ribosomes
E)in the cytosol
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21
When oxygen is in plentiful supply in the cell,pyruvate is converted to ________.
A)CoA
B)acetyl-CoA
C)glucose
D)lactate
E)fructose
A)CoA
B)acetyl-CoA
C)glucose
D)lactate
E)fructose
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22
Which of the following metabolic pathways can occur in the absence of oxygen?
A)electron transport
B)oxidative phosphorylation
C)citric acid cycle
D)glycolysis
E)β-oxidation
A)electron transport
B)oxidative phosphorylation
C)citric acid cycle
D)glycolysis
E)β-oxidation
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23
The action of pancreatic lipase on triacylglycerols produces ________.
A)emulsions
B)micelles
C)monoacylglycerols and free fatty acids
D)high-density lipoproteins
E)low-density lipoproteins
A)emulsions
B)micelles
C)monoacylglycerols and free fatty acids
D)high-density lipoproteins
E)low-density lipoproteins
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24
NAD+ participates in reactions that produce ________.
A)a CH2 group
B)a C =O bond
C)phosphorylation
D)ADP from ATP
E)a C-C bond
A)a CH2 group
B)a C =O bond
C)phosphorylation
D)ADP from ATP
E)a C-C bond
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25
In the process of glycolysis,glucose is converted to ________.
A)pyruvate
B)citrate
C)sucrose
D)oxaloacetate
E)ribose
A)pyruvate
B)citrate
C)sucrose
D)oxaloacetate
E)ribose
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26
Which coenzyme is reduced in the following reaction? 
A)FAD
B) NAD+
C)CoQ
D)NADH
E) FADH2

A)FAD
B) NAD+
C)CoQ
D)NADH
E) FADH2
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27
A chylomicron is a ________.
A)lipase
B)digestive enzyme
C)triacylglycerol
D)transport lipoprotein
E)storage protein
A)lipase
B)digestive enzyme
C)triacylglycerol
D)transport lipoprotein
E)storage protein
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28
FAD is a coenzyme which usually participates in ________.
A)oxidation of alcohols to aldehydes
B)formation of carbon-carbon double bonds
C)decarboxylation reactions
D)phosphorylation reactions
E)β-oxidation reactions
A)oxidation of alcohols to aldehydes
B)formation of carbon-carbon double bonds
C)decarboxylation reactions
D)phosphorylation reactions
E)β-oxidation reactions
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29
Glycolysis is a(n)________ process.
A)aerobic
B)anaerobic
C)anabolic
D)one-step
E)five-step
A)aerobic
B)anaerobic
C)anabolic
D)one-step
E)five-step
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30
In biochemical systems,the term reduction often refers to ________.
A)a loss of hydrogen or electrons by a compound
B)a gain of hydrogen or electrons by a compound
C)a gain in oxygen
D)a loss of electrons
E)an energy-releasing reaction
A)a loss of hydrogen or electrons by a compound
B)a gain of hydrogen or electrons by a compound
C)a gain in oxygen
D)a loss of electrons
E)an energy-releasing reaction
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31
The enzymes that break down triacylglycerols into fatty acids and glycerol are called ________.
A)lyases
B)aconitases
C)lipases
D)hydrolases
E)oxidoreductases
A)lyases
B)aconitases
C)lipases
D)hydrolases
E)oxidoreductases
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32
Fatty acids and glycerol are produced from the metabolism of ________.
A)lipids
B)proteins
C)carbohydrates
D)amino acids
E)glucose
A)lipids
B)proteins
C)carbohydrates
D)amino acids
E)glucose
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33
The compounds formed when fructose-1,6-bisphosphate is split are ________.
A)pyruvic acid and lactic acid
B)ethanol and acetyl-CoA
C)dihydroxyacetone phosphate and pyruvic acid
D)dihydroxyacetone phosphate and glyceraldehyde-3-phosphate
E)glyceraldehyde 3-phosphate and pyruvic acid
A)pyruvic acid and lactic acid
B)ethanol and acetyl-CoA
C)dihydroxyacetone phosphate and pyruvic acid
D)dihydroxyacetone phosphate and glyceraldehyde-3-phosphate
E)glyceraldehyde 3-phosphate and pyruvic acid
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34
In the absence of oxygen in muscles,pyruvate is converted to ________.
A)glycogen
B)glucose
C)ethanol
D)lactate
E)glyceraldehyde-3-phosphate
A)glycogen
B)glucose
C)ethanol
D)lactate
E)glyceraldehyde-3-phosphate
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35
The overall process of glycolysis ________.
A)requires oxygen
B)uses up 4 ATP molecules
C)requires acetyl-CoA
D)is an anabolic pathway
E)produces 2 ATP molecules
A)requires oxygen
B)uses up 4 ATP molecules
C)requires acetyl-CoA
D)is an anabolic pathway
E)produces 2 ATP molecules
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36
Coenzyme A is a molecule whose function is to ________.
A)activate enzyme A
B)undergo phosphorylation
C)provide energy for the citric acid cycle
D)activate acyl groups for reaction
E)help break down macromolecules
A)activate enzyme A
B)undergo phosphorylation
C)provide energy for the citric acid cycle
D)activate acyl groups for reaction
E)help break down macromolecules
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37
Under anaerobic conditions,lactate is produced from ________.
A)acetyl-CoA
B)pyruvate
C)ATP
D)carbon dioxide
E)NAD+
A)acetyl-CoA
B)pyruvate
C)ATP
D)carbon dioxide
E)NAD+
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38
Under aerobic conditions,pyruvate produced in glycolysis can be converted to ________.
A)glyceraldehyde-3-phosphate
B)lactic acid
C)glucose-6-phosphate
D)fructose-6-phosphate
E)acetyl-CoA
A)glyceraldehyde-3-phosphate
B)lactic acid
C)glucose-6-phosphate
D)fructose-6-phosphate
E)acetyl-CoA
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39
Which coenzyme is reduced in the following reaction?

A)FAD
B)
C)CoQ
D)NADH
E)

A)FAD
B)

C)CoQ
D)NADH
E)

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40
When one glucose molecule undergoes glycolysis it generates ________.
A)6 ATP
B)6 ATP and 2 NADH
C)2 ATP and 2 NADH
D)2 ATP and 4 NADH
E)12 ATP
A)6 ATP
B)6 ATP and 2 NADH
C)2 ATP and 2 NADH
D)2 ATP and 4 NADH
E)12 ATP
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41
The citric acid cycle is used in the oxidation of ________.
A)glucose only
B)glucose and fatty acids only
C)fatty acids only
D)glucose,fatty acids,and proteins
E)proteins only
A)glucose only
B)glucose and fatty acids only
C)fatty acids only
D)glucose,fatty acids,and proteins
E)proteins only
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42
In order to enter the citric acid cycle,pyruvate is first converted to ________.
A)lactate
B)acetaldehyde
C)citrate
D)acetyl-CoA
E)ethanol
A)lactate
B)acetaldehyde
C)citrate
D)acetyl-CoA
E)ethanol
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43
Each acetyl-CoA produces a total of ________ ATP.
A)2
B)6
C)10
D)12
E)24
A)2
B)6
C)10
D)12
E)24
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44
In the first reaction of the citric acid cycle ________.
A)glucose becomes pyruvate
B)ATP is produced
C)NADH is produced
D)acetyl-CoA reacts with oxaloacetate to give citrate
E)pyruvate becomes CO2 and H2O
A)glucose becomes pyruvate
B)ATP is produced
C)NADH is produced
D)acetyl-CoA reacts with oxaloacetate to give citrate
E)pyruvate becomes CO2 and H2O
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45
In glycolysis,glucose produces 2 pyruvate molecules and a total of ________ ATP molecules.
A)2
B)4
C)6
D)8
E)12
A)2
B)4
C)6
D)8
E)12
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46
What coenzyme(s)is(are)used in the citric acid cycle?
A)FAD only
B) NAD+ only
C)NADH + FADH2 + CoA
D)CoQ
E) NAD+ + FAD
A)FAD only
B) NAD+ only
C)NADH + FADH2 + CoA
D)CoQ
E) NAD+ + FAD
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47
In stage three of metabolism,the overall result is to release ________.
A)glucose and water
B)lactate and acetyl-CoA
C)lactate and glucose
D)glycogen and water
E)carbon dioxide and energy
A)glucose and water
B)lactate and acetyl-CoA
C)lactate and glucose
D)glycogen and water
E)carbon dioxide and energy
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48
Which of the following compounds in the citric acid cycle undergoes oxidation and decarboxylation?
A)citrate
B)isocitrate
C)succinate
D)fumarate
E)succinyl-CoA
A)citrate
B)isocitrate
C)succinate
D)fumarate
E)succinyl-CoA
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49
In the third reaction of the citric acid cycle, NAD+ is converted to ________.
A)NAS-
B)NAD2+
C)NADH2
D)NAD
E)NADH
A)NAS-
B)NAD2+
C)NADH2
D)NAD
E)NADH
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50
The citric acid cycle reaction that removes the first CO2 molecule is a(n)________.
A)oxidation and decarboxylation
B)reduction
C)phosphorylation
D)hydrolysis
E)hydration
A)oxidation and decarboxylation
B)reduction
C)phosphorylation
D)hydrolysis
E)hydration
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51
The last reaction in the citric acid cycle converts malate to ________.
A)citrate
B)isocitrate
C)succinate
D)fumarate
E)oxaloacetate
A)citrate
B)isocitrate
C)succinate
D)fumarate
E)oxaloacetate
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52
Overall,one turn of the citric acid cycle produces ________.
A)three C02 molecules
B)three NADH molecules
C)two FADH2 molecules
D)6 ATP
E)2 GTP
A)three C02 molecules
B)three NADH molecules
C)two FADH2 molecules
D)6 ATP
E)2 GTP
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53
The GTP formed in reaction 5 of the citric acid cycle is used to make ________.
A)carbon dioxide
B)oxygen
C)water
D)CoA
E)ATP
A)carbon dioxide
B)oxygen
C)water
D)CoA
E)ATP
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54
When combined with electron transport,one turn of the citric acid cycle produces ________ ATP.
A)24
B)12
C)11
D)14
E)2
A)24
B)12
C)11
D)14
E)2
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55
Reaction 5 of the citric acid cycle is the hydrolysis of succinyl-CoA.In this reaction,________.
A)the energy released is used to make GTP
B)the energy released is used to make ATP
C)carbon dioxide is released
D)α-ketoglutarate is released
E)the enzyme aconitase is needed
A)the energy released is used to make GTP
B)the energy released is used to make ATP
C)carbon dioxide is released
D)α-ketoglutarate is released
E)the enzyme aconitase is needed
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56
Most of the energy released in the citric acid cycle is used to produce ________.
A)glucose
B)acetyl-CoA
C)NADH and FADH2
D)carbon dioxide and water
E)citric acid
A)glucose
B)acetyl-CoA
C)NADH and FADH2
D)carbon dioxide and water
E)citric acid
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57
In reaction 7 of the citric acid cycle,fumarate is converted to malate in a ________ reaction.
A)hydrolysis
B)dehydrogenation
C)hydrogenation
D)hydration
E)dehydration
A)hydrolysis
B)dehydrogenation
C)hydrogenation
D)hydration
E)dehydration
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58
Under anaerobic conditions,there is a net production of ________ ATP during glycolysis.
A)zero
B)two
C)four
D)six
E)eight
A)zero
B)two
C)four
D)six
E)eight
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59
In the dehydrogenation of succinate to fumarate in the citric acid cycle,the coenzyme used is ________.
A)CoA
B)acetyl-CoA
C)NAD+
D)NADH
E)FAD
A)CoA
B)acetyl-CoA
C)NAD+
D)NADH
E)FAD
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60
The primary fuel for the synthesis of ATP is ________.
A)protein
B)lactate
C)ammonia
D)GTP
E)glucose
A)protein
B)lactate
C)ammonia
D)GTP
E)glucose
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61
The 2-carbon segments removed from a fatty acid during metabolism are used to form ________.
A)glucose
B)pyruvate
C)lactate
D)CoA
E)acetyl-CoA
A)glucose
B)pyruvate
C)lactate
D)CoA
E)acetyl-CoA
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62
In electron transport,NADH and FADH2 are used to provide ________.
A)oxygen
B)electrons and hydrogen ions
C)carbon atoms
D)water and carbon dioxide
E)thiol groups
A)oxygen
B)electrons and hydrogen ions
C)carbon atoms
D)water and carbon dioxide
E)thiol groups
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63
The complete oxidation of glucose produces ________ ATP molecules.
A)2
B)8
C)12
D)24
E)36
A)2
B)8
C)12
D)24
E)36
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64
During complete oxidation of the fatty acid
,________ molecules of acetyl-CoA are produced,and the fatty acid goes through the β-oxidation cycle ________ times.
A)ten,ten
B)nine,ten
C)nine,nine
D)nine,eight
E)ten,nine

A)ten,ten
B)nine,ten
C)nine,nine
D)nine,eight
E)ten,nine
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65
What is the net number of ATP molecules produced from the lauric acid (C12H24O2)found in coconut oil?
A)72 ATP
B)90 ATP
C)100 ATP
D)97 ATP
E)95 ATP
A)72 ATP
B)90 ATP
C)100 ATP
D)97 ATP
E)95 ATP
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66
Which step is found in the breakdown of a fatty acid?
A)an activation that requires 2 ATP.
B)an oxidation with a cytochrome c.
C)an oxidation with CoQ.
D)direct substrate phosphorylation.
E)production of pyruvate.
A)an activation that requires 2 ATP.
B)an oxidation with a cytochrome c.
C)an oxidation with CoQ.
D)direct substrate phosphorylation.
E)production of pyruvate.
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67
One example of an electron carrier in electron transport is ________.
A)ATP
B)GTP
C)coenzyme Q
D)citrate
E)water
A)ATP
B)GTP
C)coenzyme Q
D)citrate
E)water
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68
In the chemiosmotic model,protons circulate through a protein complex called ________.
A)iron-sulfur clusters
B)FMA
C)CoA
D)CoQ
E)ATP synthase
A)iron-sulfur clusters
B)FMA
C)CoA
D)CoQ
E)ATP synthase
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69
The series of reactions that produce energy by hydrolyzing fats to units of acetyl-CoA is called ________.
A)transamination
B)β-oxidation
C)hydration
D)hydrolysis
E)β-reduction
A)transamination
B)β-oxidation
C)hydration
D)hydrolysis
E)β-reduction
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70
The removal of 2-carbon segments of a fatty acid for further metabolism occurs during ________.
A)β-oxidation
B)transamination
C)deglyceration
D)dehydration
E)decarboxylation
A)β-oxidation
B)transamination
C)deglyceration
D)dehydration
E)decarboxylation
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71
The components of electron transport do not include ________.
A)oxygen (O2)
B)cytochrome c
C)Complex II
D)CoQ
E)acetyl-CoA
A)oxygen (O2)
B)cytochrome c
C)Complex II
D)CoQ
E)acetyl-CoA
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72
The reduced coenzyme ________ provides two ATP via electron transport.
A) FADH2
B)NADH
C)NADPH
D)CoASH
E) FNMH2
A) FADH2
B)NADH
C)NADPH
D)CoASH
E) FNMH2
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73
The 2-carbon units obtained by degradation of a fatty acid are further metabolized in ________.
A)oxidative deamination
B)the citric acid cycle
C)β-oxidation
D)glycolysis
E)transamination
A)oxidative deamination
B)the citric acid cycle
C)β-oxidation
D)glycolysis
E)transamination
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74
In the activation of a fatty acid,energy from the hydrolysis of ATP is used to ________.
A)form a double bond in an oxidation reaction
B)join the fatty acid to CoA
C)add a molecule of water across a double bond to give a hydroxyl group on the β-carbon
D)oxidize the hydroxyl group on the β-carbon
E)cause a unit of acetyl-CoA to separate from the fatty acid chain
A)form a double bond in an oxidation reaction
B)join the fatty acid to CoA
C)add a molecule of water across a double bond to give a hydroxyl group on the β-carbon
D)oxidize the hydroxyl group on the β-carbon
E)cause a unit of acetyl-CoA to separate from the fatty acid chain
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75
What is the correct coefficient for ATP in the complete combustion of glucose? 
A)6
B)12
C)18
D)24
E)36

A)6
B)12
C)18
D)24
E)36
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76
The energy released during electron transport is used to produce ________.
A)glucose
B)citric acid
C)carbon dioxide
D)ATP
E)NADH
A)glucose
B)citric acid
C)carbon dioxide
D)ATP
E)NADH
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77
The compounds in electron transport that remove hydrogen ions and electrons from NADH are classified as ________.
A)oxidative transporters
B)osmotic carriers
C)electron carriers
D)phosphorylators
E)citrates
A)oxidative transporters
B)osmotic carriers
C)electron carriers
D)phosphorylators
E)citrates
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78
In electron transport,the synthesis of ATP from ADP + Pi is called ________.
A)glycolysis
B)acylation
C)oxidative phosphorylation
D)isomerization
E)hydrolysis
A)glycolysis
B)acylation
C)oxidative phosphorylation
D)isomerization
E)hydrolysis
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79
In the chemiosmotic model of oxidative phosphorylation,ATP is synthesized as ________.
A) OH- flows through ATP synthase
B)electrons flow through ATP synthase
C) CA2+ flows through ATP synthase
D) H+ flows through ATP synthase
E) Na+ flows through ATP synthase
A) OH- flows through ATP synthase
B)electrons flow through ATP synthase
C) CA2+ flows through ATP synthase
D) H+ flows through ATP synthase
E) Na+ flows through ATP synthase
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80
The complete oxidation of CH3-(CH2)8 -COOH produces a net of ________ molecules of ATP.
A)80
B)78
C)82
D)74
E)76
A)80
B)78
C)82
D)74
E)76
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