Deck 10: Gene Action: From DNA to Protein
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Deck 10: Gene Action: From DNA to Protein
1
Cells replicate DNA
A)during the M phase of the cell cycle.
B)all the time.
C)during the S phase of the cell cycle.
D)only when a person is stresseD.
A)during the M phase of the cell cycle.
B)all the time.
C)during the S phase of the cell cycle.
D)only when a person is stresseD.
C
2
Identify a true statement about RNA.
A)RNA has the pyramidine base thymine.
B)RNA nucleotides include the sugar dexyribose.
C)RNA is more stable than DNA.
D)RNA controls the use of genetic information.
A)RNA has the pyramidine base thymine.
B)RNA nucleotides include the sugar dexyribose.
C)RNA is more stable than DNA.
D)RNA controls the use of genetic information.
D
3
Ribose is an important component of RNA because
A)it is less stable than deoxyribose,which enables RNA to function as a short-term carrier of genetic information.
B)it is less stable than deoxyribose,which enables RNA to function as a long-term carrier of genetic information.
C)it is more stable than deoxyribose,which enables RNA to function as a long-term carrier of genetic information.
D)it is as stable as deoxyribose,which makes RNA and DNA functionally equivalent.
A)it is less stable than deoxyribose,which enables RNA to function as a short-term carrier of genetic information.
B)it is less stable than deoxyribose,which enables RNA to function as a long-term carrier of genetic information.
C)it is more stable than deoxyribose,which enables RNA to function as a long-term carrier of genetic information.
D)it is as stable as deoxyribose,which makes RNA and DNA functionally equivalent.
A
4
Which choice is the correct sequence from smallest to largest?
A)Amino acid,peptide,polypeptide,protein
B)Protein,polypeptide,peptide,amino acid
C)Amino acid,DNA,peptide,gene
D)Peptide,polypeptide,amino acid,protein
A)Amino acid,peptide,polypeptide,protein
B)Protein,polypeptide,peptide,amino acid
C)Amino acid,DNA,peptide,gene
D)Peptide,polypeptide,amino acid,protein
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5
The nitrogenous base that is in RNA but not in DNA is
A)thymine.
B)thiamine.
C)uracil.
D)urea.
A)thymine.
B)thiamine.
C)uracil.
D)urea.
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6
About _____ percent of the human genome is the exome.
A)0.5
B)1.5
C)5.0
D)10
A)0.5
B)1.5
C)5.0
D)10
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7
RNA differs from DNA in that
A)it is usually single-stranded.
B)it is usually double-stranded.
C)it has thymine instead of uracil.
D)it has deoxyribose instead of ribose.
A)it is usually single-stranded.
B)it is usually double-stranded.
C)it has thymine instead of uracil.
D)it has deoxyribose instead of ribose.
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8
An mRNA molecule is also called a(n)
A)intron.
B)transcript.
C)gene.
D)proscript.
A)intron.
B)transcript.
C)gene.
D)proscript.
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9
Which of these is not found in RNA?
A)phosphate
B)deoxyribose
C)purines
D)ribose
A)phosphate
B)deoxyribose
C)purines
D)ribose
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10
A retrovirus produces an enzyme,called reverse transcriptase,which copies its RNA genome into DNA.This is opposite of the central dogma because
A)a virus is not an organism.
B)a virus lacks genetic material.
C)a retrovirus lacks DNA.
D)the central dogma states that DNA is copied into RNA.
A)a virus is not an organism.
B)a virus lacks genetic material.
C)a retrovirus lacks DNA.
D)the central dogma states that DNA is copied into RNA.
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11
The portion of the human genome that encodes protein is termed the
A)exon
B)template
C)proteasome
D)exome
A)exon
B)template
C)proteasome
D)exome
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12
To express a gene,DNA is first transcribed into a corresponding strand of
A)mtDNA.
B)rRNA.
C)mRNA.
D)tRNA.
A)mtDNA.
B)rRNA.
C)mRNA.
D)tRNA.
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13
Which of the following descriptions of genetic information flow best illustrates the central dogma of biology?
A)DNA to RNA to protein
B)RNA to DNA to protein
C)protein to DNA to protein
D)protein to RNA to DNA
A)DNA to RNA to protein
B)RNA to DNA to protein
C)protein to DNA to protein
D)protein to RNA to DNA
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14
The DNA template ATGCGTTA is transcribed into an RNA strand with the sequence
A)TACGCAAT.
B)UAACGCAU.
C)UACGCAAU.
D)AUGCGAAU.
A)TACGCAAT.
B)UAACGCAU.
C)UACGCAAU.
D)AUGCGAAU.
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15
Watson and Crick describe the relationship between _____ as a directional flow of information called the "central dogma".
A)nucleic acids and proteins
B)enzymes and proteins
C)peptides and polypeptides
D)DNA and RNA
A)nucleic acids and proteins
B)enzymes and proteins
C)peptides and polypeptides
D)DNA and RNA
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16
A genetic code word is called a(n)
A)proton.
B)codon.
C)nodoC.
D)amino aciD.
A)proton.
B)codon.
C)nodoC.
D)amino aciD.
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17
In transcription,one DNA strand is transcribed into a(n)_____ RNA strand,which is translated into protein.
A)ribosomal
B)transfer
C)messenger
D)anticodon
A)ribosomal
B)transfer
C)messenger
D)anticodon
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18
Place the types of RNA molecules in correct size order,from smallest to largest.
A)mRNA,tRNA,rRNA
B)aRNA,bRNA,cRNA
C)tRNA,rRNA,mRNA
D)tDNA,rDNA,mDNA
A)mRNA,tRNA,rRNA
B)aRNA,bRNA,cRNA
C)tRNA,rRNA,mRNA
D)tDNA,rDNA,mDNA
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19
During transcription
A)protein is synthesized from DNA.
B)DNA is replicated.
C)RNA is synthesized from DNA.
D)protein is synthesized from amino acids.
A)protein is synthesized from DNA.
B)DNA is replicated.
C)RNA is synthesized from DNA.
D)protein is synthesized from amino acids.
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20
DNA replication is necessary so that
A)transcription can proceed.
B)translation can proceed.
C)genetic information is not lost as the information in DNA sequences is accessed.
D)the cell does not die when it divides.
A)transcription can proceed.
B)translation can proceed.
C)genetic information is not lost as the information in DNA sequences is accessed.
D)the cell does not die when it divides.
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21
Which codons are synonymous?
A)CAC and CAG
B)CAC and CAU
C)ACA and AGC
D)UCC and GAC
A)CAC and CAG
B)CAC and CAU
C)ACA and AGC
D)UCC and GAC
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22
If part of a DNA template is the sequence GTTAGTCTGTGGGCT,then the DNA coding strand has the sequence
A)GTTAGTCTGTGGGCT.
B)CAATCAGACACCCGA.
C)CAAUCAGACACCCGA.
D)GAATCAGACACCCGA.
A)GTTAGTCTGTGGGCT.
B)CAATCAGACACCCGA.
C)CAAUCAGACACCCGA.
D)GAATCAGACACCCGA.
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23
A benefit of alternate splicing of introns out of mRNAs is that
A)it maximizes the number of introns.
B)it increases the number of proteins that the genome encodes.
C)it lowers the risk of infection.
D)it speeds transcription.
A)it maximizes the number of introns.
B)it increases the number of proteins that the genome encodes.
C)it lowers the risk of infection.
D)it speeds transcription.
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24
A mutation that adds one or two bases to a gene disrupts the
A)replicating frame.
B)intron index.
C)genetic code.
D)reading frame.
A)replicating frame.
B)intron index.
C)genetic code.
D)reading frame.
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25
After transcription and before translation,eukaryotic mRNA is modified by adding
A)tRNAs and amino acids.
B)amino acids and a poly-A tail.
C)a cap of modified nucleotides and a poly-A tail.
D)an AUG at one end and a poly-U tail at the other.
A)tRNAs and amino acids.
B)amino acids and a poly-A tail.
C)a cap of modified nucleotides and a poly-A tail.
D)an AUG at one end and a poly-U tail at the other.
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26
Rett syndrome and homeotic mutations result from mutations in _____.
A)transcription factors
B)mRNA molecules
C)exons
D)spliceosomes
A)transcription factors
B)mRNA molecules
C)exons
D)spliceosomes
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27
Ribosomal RNAs
A)are translated from DNA.
B)are synthesized by ribosomes.
C)connect codons to amino acids.
D)associates with proteins to form ribosomes.
A)are translated from DNA.
B)are synthesized by ribosomes.
C)connect codons to amino acids.
D)associates with proteins to form ribosomes.
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28
The genetic code is
A)triplet,overlapping,and not universal.
B)triplet,non-overlapping,and universal.
C)quarternary,overlapping,and non-universal.
D)singular,non-overlapping,and universal.
A)triplet,overlapping,and not universal.
B)triplet,non-overlapping,and universal.
C)quarternary,overlapping,and non-universal.
D)singular,non-overlapping,and universal.
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29
The scientists who identified a set of coordinately regulated genes,called an operon,responsible for lactose metabolism in
A)Watson and Crick.
B)Meselson and Stahl.
C)Jacob and Monod.
D)Hershey and Chase.
E)coli were
A)Watson and Crick.
B)Meselson and Stahl.
C)Jacob and Monod.
D)Hershey and Chase.
E)coli were
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30
Parts of an mRNA molecule that are removed before protein synthesis are called
A)exons.
B)exomes.
C)promoters.
D)introns.
A)exons.
B)exomes.
C)promoters.
D)introns.
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31
A codon consists of three consecutive
A)DNA bases.
B)amino acids.
C)tRNA bases
D)mRNA bases.
A)DNA bases.
B)amino acids.
C)tRNA bases
D)mRNA bases.
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32
In a bacterial cell,the three genes of the lactose operon are
A)expressed continuously.
B)expressed when lactose synthesis is required.
C)expressed only in the presence of lactose.
D)never expressed,because they are pseudogenes.
A)expressed continuously.
B)expressed when lactose synthesis is required.
C)expressed only in the presence of lactose.
D)never expressed,because they are pseudogenes.
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33
_____ consist of proteins and RNAs that associate,providing both a physical support and enzyme activity for protein synthesis.
A)Nucleosomes
B)Ribosomes
C)Nuclei
D)Histones
A)Nucleosomes
B)Ribosomes
C)Nuclei
D)Histones
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34
Transcription factors function in the expression of genes by
A)initiating transcription.
B)associating to initiate translation.
C)turning transcription of specific genes on or off.
D)halting the activity of RNA polymerase at the end of transcription.
A)initiating transcription.
B)associating to initiate translation.
C)turning transcription of specific genes on or off.
D)halting the activity of RNA polymerase at the end of transcription.
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35
Transcription and replication are alike in that both
A)are guided by complementary base pairing.
B)are regulated by homeobox genes.
C)require DNA polymerase.
D)require a promoter and RNA polymerase.
A)are guided by complementary base pairing.
B)are regulated by homeobox genes.
C)require DNA polymerase.
D)require a promoter and RNA polymerase.
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36
Which codon halts ribosomes?
A)UAG
B)AUG
C)UUU
D)ATG
A)UAG
B)AUG
C)UUU
D)ATG
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37
The enzyme that synthesizes messenger RNA from a DNA template is
A)DNA polymerase.
B)RNA polymerase.
C)reverse transcriptase.
D)ligase.
A)DNA polymerase.
B)RNA polymerase.
C)reverse transcriptase.
D)ligase.
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38
There are _____ different sequences of codons possible in the genetic code.
A)3
B)4
C)16
D)64
A)3
B)4
C)16
D)64
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39
In transcription,the promoter is
A)an enzyme that binds DNA.
B)a series of proteins that collectively bind to DNA.
C)a recognition sequence in RNA that attracts ribosomes.
D)A DNA sequence that RNA polymerase binds.
A)an enzyme that binds DNA.
B)a series of proteins that collectively bind to DNA.
C)a recognition sequence in RNA that attracts ribosomes.
D)A DNA sequence that RNA polymerase binds.
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40
B is an intron between two exons, A and C. Which representation best describes how this region of mRNA will appear after it is transcribed and processed by a spliceosome?
A)A-C
B)A-B
C)B-C
D)A-B-C
A)A-C
B)A-B
C)B-C
D)A-B-C
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41
If part of a DNA template is the sequence GTTAGTCTGTGGGCT,then the mRNA transcribed from it is
A)GTTAGTCTGTGGGCT.
B)CAATCAGACACCCGA.
C)CAAUCAGACACCCGA.
D)gln-ser-asp-thr-arg.
A)GTTAGTCTGTGGGCT.
B)CAATCAGACACCCGA.
C)CAAUCAGACACCCGA.
D)gln-ser-asp-thr-arg.
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42
Ribosomes begin translation of an mRNA transcript at the first
A)anticodon.
B)AUG.
C)promoter.
D)tRNA.
A)anticodon.
B)AUG.
C)promoter.
D)tRNA.
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43
_____ proteins stabilize partially folded parts of proteins in their correct form.
A)Chaperone
B)Signal sequences
C)Proteasomes
D)Ubiquitin
A)Chaperone
B)Signal sequences
C)Proteasomes
D)Ubiquitin
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44
A sequence of DNA could have _____ possible reading frame(s).
A)two
B)three
C)four
D)an infinite number of
A)two
B)three
C)four
D)an infinite number of
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45
The linear order of amino acids in a polypeptide is the _____ structure of a protein.
A)primary
B)secondary
C)tertiary
D)quaternary
A)primary
B)secondary
C)tertiary
D)quaternary
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46
Diseases that are caused by protein misfolding include
A)tuberculosis and AIDS.
B)river blindness and African sleeping sickness.
C)cystic fibrosis and Huntington disease.
D)acne and insomnia.
A)tuberculosis and AIDS.
B)river blindness and African sleeping sickness.
C)cystic fibrosis and Huntington disease.
D)acne and insomnia.
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47
A prion is a(n)
A)very small virus.
B)a virus built only of protein.
C)a glycoprotein that has multiple conformations and may be infectious.
D)a subatomic particle,along with a neutron and an electron.
A)very small virus.
B)a virus built only of protein.
C)a glycoprotein that has multiple conformations and may be infectious.
D)a subatomic particle,along with a neutron and an electron.
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48
_____ bonds form between amino acids during elongation.
A)Disulfide
B)Peptide
C)Hydrogen
D)Glycine
A)Disulfide
B)Peptide
C)Hydrogen
D)Glycine
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49
The genetic code was deciphered
A)in the year 2000,following several years of the human genome project.
B)in the 1980s,as many Mendelian diseases had their genes identified.
C)in the 1960s.
D)in the 1950s.
A)in the year 2000,following several years of the human genome project.
B)in the 1980s,as many Mendelian diseases had their genes identified.
C)in the 1960s.
D)in the 1950s.
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50
The large ribosomal subunit joins the initiation complex to begin _____ during translation.
A)association
B)initiation
C)elongation
D)termination
A)association
B)initiation
C)elongation
D)termination
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51
A signal sequence
A)directs RNA nucleotides to a particular gene.
B)attracts tRNAs to an mRNA.
C)is the first part of a protein's amino acid sequence that helps to direct it to a certain part of the cell.
D)is a coding codon that mutates into a stop codon.
A)directs RNA nucleotides to a particular gene.
B)attracts tRNAs to an mRNA.
C)is the first part of a protein's amino acid sequence that helps to direct it to a certain part of the cell.
D)is a coding codon that mutates into a stop codon.
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52
A(n)_____ carries a specific amino acid to a ribosome,where the amino acid bonds to another.
A)mtDNA
B)rRNA
C)mRNA
D)tRNA
A)mtDNA
B)rRNA
C)mRNA
D)tRNA
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53
The sequences UUUUUUUUU ¼,AAAAAAAAA¼,and CCCCCCCCC¼,were the first to be analyzed to crack the genetic code because
A)they were the simplest to synthesize.
B)they would encode all types of amino acids.
C)they would encode only one type of nucleotide.
D)they would encode only one type of amino aciD.
A)they were the simplest to synthesize.
B)they would encode all types of amino acids.
C)they would encode only one type of nucleotide.
D)they would encode only one type of amino aciD.
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54
_____ "tag" misfolded proteins so that they can be refolded or sent to proteasomes.
A)Chaperones
B)Folding catalysts
C)Signal sequences
D)Ubiquitin molecules
A)Chaperones
B)Folding catalysts
C)Signal sequences
D)Ubiquitin molecules
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55
A ribozyme is
A)an RNA-protein complex that cleaves DNA.
B)an enzyme that catalyzes the assembly of ribosomes.
C)a small RNA that can catalyze a specific chemical reaction.
D)a stretch of uracil in RNA that directs splicing.
A)an RNA-protein complex that cleaves DNA.
B)an enzyme that catalyzes the assembly of ribosomes.
C)a small RNA that can catalyze a specific chemical reaction.
D)a stretch of uracil in RNA that directs splicing.
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56
Part of a DNA template of sequence GTTAGTCTGTGGGCT corresponds to the amino acid sequence
A)GTTAGTCTGTGGGCT.
B)CAAUCAGACACCCGA.
C)gln-ser-asp-thr-arg.
D)val-ser-leu-trp-ala.
A)GTTAGTCTGTGGGCT.
B)CAAUCAGACACCCGA.
C)gln-ser-asp-thr-arg.
D)val-ser-leu-trp-ala.
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57
A mutation that changes one particular amino acid into another can affect the functioning of other amino acids farther away in the primary sequence due to
A)the presence of prions.
B)protein folding.
C)jumping genes.
D)the tendency for further mutations to occur.
A)the presence of prions.
B)protein folding.
C)jumping genes.
D)the tendency for further mutations to occur.
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58
_____ tRNAs are required to translate the DNA template sequence GTTACTCTGTGGGCT into amino acids.3-26-2013
A)Two
B)Three
C)Four
D)Twenty
A)Two
B)Three
C)Four
D)Twenty
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