Deck 13: Microbe-Human Interactions: Infection and Disease
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Deck 13: Microbe-Human Interactions: Infection and Disease
1
STORCH is an acronym that represents the most common
A)genera of resident flora.
B)sexually transmitted diseases.
C)portals of entry.
D)vectors.
E)infections of the fetus and neonate.
A)genera of resident flora.
B)sexually transmitted diseases.
C)portals of entry.
D)vectors.
E)infections of the fetus and neonate.
E
2
The human body typically begins to be colonized by its normal flora
A)before birth, in utero.
B)during, and immediately after birth.
C)when a child first goes to school.
D)when an infant gets its first infectious disease.
E)during puberty.
A)before birth, in utero.
B)during, and immediately after birth.
C)when a child first goes to school.
D)when an infant gets its first infectious disease.
E)during puberty.
B
3
The time from when pathogen first enters the body and begins to multiply, until symptoms first appear is the
A)prodromal stage.
B)convalescent stage.
C)incubation period.
D)period of invasion.
E)All of the choices are correct.
A)prodromal stage.
B)convalescent stage.
C)incubation period.
D)period of invasion.
E)All of the choices are correct.
C
4
Resident flora are found in/on the
A)skin.
B)mouth.
C)nasal passages.
D)large intestine.
E)All of the choices are correct.
A)skin.
B)mouth.
C)nasal passages.
D)large intestine.
E)All of the choices are correct.
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5
Which genus is the most common resident flora of mouth surfaces?
A)Lactobacillus
B)Streptococcus
C)Haemophilus
D)Escherichia
E)Mycobacterium
A)Lactobacillus
B)Streptococcus
C)Haemophilus
D)Escherichia
E)Mycobacterium
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6
Which genus is resident flora of the mouth, large intestine, and, from puberty to menopause, the vagina?
A)Lactobacillus
B)Streptococcus
C)Haemophilus
D)Escherichia
E)Mycobacterium
A)Lactobacillus
B)Streptococcus
C)Haemophilus
D)Escherichia
E)Mycobacterium
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7
Resident flora of the intestines include
A)Streptococcus.
B)Bacteroides.
C)Staphylococcus.
D)Haemophilus.
E)All of the choices are correct.
A)Streptococcus.
B)Bacteroides.
C)Staphylococcus.
D)Haemophilus.
E)All of the choices are correct.
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8
All infectious diseases
A)are contagious.
B)only occur in humans.
C)are caused by microorganisms or their products.
D)are caused by vectors.
E)involve viruses as the pathogen.
A)are contagious.
B)only occur in humans.
C)are caused by microorganisms or their products.
D)are caused by vectors.
E)involve viruses as the pathogen.
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9
The body site with resident flora that produces beneficial body products, including vitamin K and several other vitamins is the
A)skin.
B)mouth.
C)large intestine.
D)vagina.
E)nasal passages.
A)skin.
B)mouth.
C)large intestine.
D)vagina.
E)nasal passages.
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10
Microbial hyaluronidase, coagulase, and streptokinase are examples of
A)adhesive factors.
B)exotoxins.
C)hemolysins.
D)antiphagocytic factors.
E)exoenzymes.
A)adhesive factors.
B)exotoxins.
C)hemolysins.
D)antiphagocytic factors.
E)exoenzymes.
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11
Which is mismatched?
A)Fimbriae - adherence to substrate
B)Capsules - antiphagocytic factor
C)Coagulase - dissolve fibrin clots
D)Leukocidins - damage white blood cells
E)Hemolysins - damage red blood cells
A)Fimbriae - adherence to substrate
B)Capsules - antiphagocytic factor
C)Coagulase - dissolve fibrin clots
D)Leukocidins - damage white blood cells
E)Hemolysins - damage red blood cells
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12
Exotoxins are
A)proteins.
B)only released after a cell is damaged or lysed.
C)antiphagocytic factors.
D)secretions that always target nervous tissue.
E)lipopolysaccharides.
A)proteins.
B)only released after a cell is damaged or lysed.
C)antiphagocytic factors.
D)secretions that always target nervous tissue.
E)lipopolysaccharides.
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13
Which is not the terminology used for resident flora?
A)Pathogenic flora
B)Normal flora
C)Indigenous flora
D)Normal microflora
E)All of the choices are correct
A)Pathogenic flora
B)Normal flora
C)Indigenous flora
D)Normal microflora
E)All of the choices are correct
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14
Endogenous infectious agents arise from microbes that are
A)in food.
B)the patient's own normal flora.
C)on fomites.
D)in the air.
E)transmitted from one person to another.
A)in food.
B)the patient's own normal flora.
C)on fomites.
D)in the air.
E)transmitted from one person to another.
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15
All of the following genera are considered resident flora of skin sites, except
A)Escherichia.
B)Staphylococcus.
C)Corynebacterium.
D)Micrococcus.
E)Mycobacterium.
A)Escherichia.
B)Staphylococcus.
C)Corynebacterium.
D)Micrococcus.
E)Mycobacterium.
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16
Enterotoxins are
A)virulence factors.
B)toxins that target the intestines.
C)proteins.
D)exotoxins.
E)All of the choices are correct.
A)virulence factors.
B)toxins that target the intestines.
C)proteins.
D)exotoxins.
E)All of the choices are correct.
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17
Infection occurs when
A)contaminants are present on the skin.
B)a person swallows microbes in/on food.
C)a person inhales microbes in the air.
D)pathogens enter and multiply in body tissues.
E)All of the choices are correct.
A)contaminants are present on the skin.
B)a person swallows microbes in/on food.
C)a person inhales microbes in the air.
D)pathogens enter and multiply in body tissues.
E)All of the choices are correct.
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18
The stage of an infectious disease when specific signs and symptoms are seen and the pathogen is at peak activity is
A)prodromal stage.
B)convalescent stage.
C)incubation period.
D)period of invasion.
E)All of the choices are correct.
A)prodromal stage.
B)convalescent stage.
C)incubation period.
D)period of invasion.
E)All of the choices are correct.
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19
Virulence factors include all the following, except
A)capsules.
B)ribosomes.
C)exoenzymes.
D)endotoxin.
E)exotoxin.
A)capsules.
B)ribosomes.
C)exoenzymes.
D)endotoxin.
E)exotoxin.
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20
The initial, brief period of early, general symptoms such as fatigue and muscle aches, is the
A)prodromal stage.
B)convalescent stage.
C)incubation period.
D)period of invasion.
E)All of the choices are correct.
A)prodromal stage.
B)convalescent stage.
C)incubation period.
D)period of invasion.
E)All of the choices are correct.
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21
Nosocomial infections involve all the following, except
A)they are only transmitted by medical personnel.
B)they often involve the patient's urinary tract and surgical incisions.
C)the patient's resident flora can be the infectious agent.
D)Escherichia coli and staphylococci are common infectious agents.
E)medical and surgical asepsis help lower their occurrence.
A)they are only transmitted by medical personnel.
B)they often involve the patient's urinary tract and surgical incisions.
C)the patient's resident flora can be the infectious agent.
D)Escherichia coli and staphylococci are common infectious agents.
E)medical and surgical asepsis help lower their occurrence.
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22
A disease that has a steady frequency over time in a population is
A)epidemic.
B)endemic.
C)pandemic.
D)sporadic.
E)chronic.
A)epidemic.
B)endemic.
C)pandemic.
D)sporadic.
E)chronic.
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23
Animals that participate in the life cycles of pathogens and transmit pathogens from host to host are
A)fomites.
B)aerosols.
C)mechanical vectors.
D)droplet nuclei.
E)biological vectors.
A)fomites.
B)aerosols.
C)mechanical vectors.
D)droplet nuclei.
E)biological vectors.
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24
The dried residues of fine droplets from mucus or saliva that harbor and transmit pathogen are
A)fomites.
B)aerosols.
C)mechanical vectors.
D)droplet nuclei.
E)biological vectors.
A)fomites.
B)aerosols.
C)mechanical vectors.
D)droplet nuclei.
E)biological vectors.
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25
The number of new cases of a disease in a population over a specific period of time compared with the healthy population is the
A)mortality rate.
B)morbidity rate.
C)incidence rate.
D)prevalence rate.
E)epidemic rate.
A)mortality rate.
B)morbidity rate.
C)incidence rate.
D)prevalence rate.
E)epidemic rate.
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26
Local edema, swollen lymph nodes, fever, soreness, and abscesses are indications of
A)toxemia.
B)inflammation.
C)sequelae.
D)a syndrome.
E)latency.
A)toxemia.
B)inflammation.
C)sequelae.
D)a syndrome.
E)latency.
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27
An animal, such as an arthropod, that transmits a pathogen from one host to another is a
A)fomite.
B)carrier.
C)vector.
D)reservoir.
E)source.
A)fomite.
B)carrier.
C)vector.
D)reservoir.
E)source.
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28
The principal government agency responsible for tracking infectious diseases in the United States is the
A)Centers for Disease Control and Prevention.
B)World Health Organization.
C)National Institutes of Health.
D)United States Department of Agriculture.
E)Infection Control Committee.
A)Centers for Disease Control and Prevention.
B)World Health Organization.
C)National Institutes of Health.
D)United States Department of Agriculture.
E)Infection Control Committee.
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29
Which is mismatched?
A)Secondary infection - infection spreads to several tissue sites
B)Mixed infection - several agents established at infection site
C)Acute infection - rapid onset of severe, short-lived symptoms
D)Local infection - pathogen remains at or near entry site
E)Toxemia - pathogen's toxins carried by the blood to target tissues
A)Secondary infection - infection spreads to several tissue sites
B)Mixed infection - several agents established at infection site
C)Acute infection - rapid onset of severe, short-lived symptoms
D)Local infection - pathogen remains at or near entry site
E)Toxemia - pathogen's toxins carried by the blood to target tissues
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30
A laboratory technologist splashed a blood specimen onto his face, eyes, nose, and mouth.This specimen was from an HIV positive patient.If this blood exposure leads to HIV infection in the technologist, the transmission route is
A)direct.
B)fomite.
C)vehicle.
D)droplet nuclei.
E)aerosols.
A)direct.
B)fomite.
C)vehicle.
D)droplet nuclei.
E)aerosols.
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31
Which of the following is an example of vertical transmission?
A)Drinking contaminated water.
B)A sneeze transmitting a cold.
C)Oral-fecal transmission involving a diaper.
D)A mosquito bite.
E)A mother transmitting syphilis to her fetus.
A)Drinking contaminated water.
B)A sneeze transmitting a cold.
C)Oral-fecal transmission involving a diaper.
D)A mosquito bite.
E)A mother transmitting syphilis to her fetus.
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32
The study of the frequency and distribution of a disease in a defined population is
A)pathology.
B)clinical microbiology.
C)medicine.
D)immunology.
E)epidemiology.
A)pathology.
B)clinical microbiology.
C)medicine.
D)immunology.
E)epidemiology.
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33
When would Koch's Postulates be utilized?
A)To determine the cause of a patient's illness in a hospital microbiology lab.
B)To develop a new antibiotic in a pharmaceutical lab.
C)To determine the cause of a new disease in a microbiology research lab.
D)To formulate a vaccine against a new pathogen in a genetic engineering lab.
E)Whenever the scientific method is used to investigate a microbiological problem.
A)To determine the cause of a patient's illness in a hospital microbiology lab.
B)To develop a new antibiotic in a pharmaceutical lab.
C)To determine the cause of a new disease in a microbiology research lab.
D)To formulate a vaccine against a new pathogen in a genetic engineering lab.
E)Whenever the scientific method is used to investigate a microbiological problem.
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34
An inanimate object that harbors and transmits a pathogen is a
A)fomite.
B)carrier.
C)vector.
D)reservoir.
E)source.
A)fomite.
B)carrier.
C)vector.
D)reservoir.
E)source.
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35
The subjective evidence of disease sensed by the patient is termed
A)syndrome.
B)symptom.
C)sign.
D)pathology.
E)inflammation.
A)syndrome.
B)symptom.
C)sign.
D)pathology.
E)inflammation.
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36
Reservoirs include
A)humans
B)animals
C)soil
D)water
E)All of the choices are correct
A)humans
B)animals
C)soil
D)water
E)All of the choices are correct
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37
All of the following are correct about mechanical vectors, except
A)cockroaches are an example.
B)the vector can carry the pathogen on its feet and mouthparts.
C)the vector is important to the life cycle of the infectious agent.
D)they can spread viral, bacterial, protozoan, and worm infections.
E)some, like flies feed on garbage and feces.
A)cockroaches are an example.
B)the vector can carry the pathogen on its feet and mouthparts.
C)the vector is important to the life cycle of the infectious agent.
D)they can spread viral, bacterial, protozoan, and worm infections.
E)some, like flies feed on garbage and feces.
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38
The objective, measurable evidence of disease evaluated by an observer is termed
A)syndrome.
B)symptom.
C)sign.
D)pathology.
E)inflammation.
A)syndrome.
B)symptom.
C)sign.
D)pathology.
E)inflammation.
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39
Someone who inconspicuously harbors a pathogen and spreads it to others is a
A)fomite.
B)carrier.
C)vector.
D)reservoir.
E)source.
A)fomite.
B)carrier.
C)vector.
D)reservoir.
E)source.
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40
The primary, natural habitat of a pathogen where it continues to exist is called the
A)fomite.
B)carrier.
C)vector.
D)reservoir.
E)source.
A)fomite.
B)carrier.
C)vector.
D)reservoir.
E)source.
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41
The virulence factors of a pathogen are established by how strong or weak a patient's body defenses are at the time of infection.
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42
Fomites, food, and air serve as indirect transmission routes of pathogens.
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43
Which of the following is correct about skatole?
A)It is the general term for the flora of the gastrointestinal tract.
B)It is a mixture of amines and gases that gives feces its characteristic stench.
C)It is another term for the sexually transmitted disease, syphilis.
D)It is a general term for the endogenous flora in humans.
E)It is a chemical released by gram positive rods during inflammation.
A)It is the general term for the flora of the gastrointestinal tract.
B)It is a mixture of amines and gases that gives feces its characteristic stench.
C)It is another term for the sexually transmitted disease, syphilis.
D)It is a general term for the endogenous flora in humans.
E)It is a chemical released by gram positive rods during inflammation.
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44
A student has their teeth cleaned.The hygienist nicks their gum tissue.The student develops endocarditis due to Streptococcus.What kind of pattern of infection is this?
A)Localized
B)Mixed Infection
C)Focal
D)Systemic
E)All of the choices are correct
A)Localized
B)Mixed Infection
C)Focal
D)Systemic
E)All of the choices are correct
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45
When a disease occurs occasionally at irregular intervals and random locales, it is referred to as
A)sporadic.
B)pandemic.
C)endemic.
D)epidemic.
E)chronic.
A)sporadic.
B)pandemic.
C)endemic.
D)epidemic.
E)chronic.
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46
When an infected person is in the incubation period, that person cannot transmit the pathogen to others.
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47
All of the following are signs of infectious diseases, except
A)fever.
B)leucopenia.
C)swollen lymph nodes.
D)antibodies in serum.
E)nausea.
A)fever.
B)leucopenia.
C)swollen lymph nodes.
D)antibodies in serum.
E)nausea.
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48
A fetus can get an infection when a pathogen in the mother's blood is capable of crossing the placenta to the fetal circulation and tissues.
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49
The Centers for Disease Control and Prevention assigns the most virulent microbes known to cause human disease to biosafety level 4.
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50
A person with which occupation is most at risk for a zoonotic disease?
A)accountant
B)teacher
C)nurse
D)dental hygienist
E)forest ranger
A)accountant
B)teacher
C)nurse
D)dental hygienist
E)forest ranger
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51
Under certain circumstances, a person's resident flora can be opportunistic pathogens.
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52
Joe contracted Hepatitis A by eating contaminated doughnuts from a local bakery.The source of the disease is ___________ and the reservoir is ______________.
A)Joe, the doughnut
B)the doughnut, humans
C)humans, flour
D)flour, Joe
E)humans, Joe
A)Joe, the doughnut
B)the doughnut, humans
C)humans, flour
D)flour, Joe
E)humans, Joe
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53
Most of the skin's resident flora is found in the uppermost, superficial layers of the epidermis.
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54
If the ID for gonorrhea is 1,000 cells and the ID for tuberculosis is 10 cells, which organism is more virulent?
A)Neisseria gonorrhea
B)Mycobacterium tuberculosis
C)They are equally virulent
D)It is impossible to determine
A)Neisseria gonorrhea
B)Mycobacterium tuberculosis
C)They are equally virulent
D)It is impossible to determine
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55
Septicemia means that a pathogen is present and multiplying in the blood.
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56
Sentinel animals are monitored for specific diseases in order to determine the potential for human exposure to a disease.
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57
Marion is going to the hospital for a triple bypass operation.She will have general anesthesia, intravenous catheter, surgical wounds, and a urinary catheter.Which nosocomial infection is she at greatest risk for contracting?
A)respiratory
B)septicemia
C)urinary tract
D)surgical site
E)meningitis
A)respiratory
B)septicemia
C)urinary tract
D)surgical site
E)meningitis
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58
Some diseases can be vertically transmitted.This is understood to mean the disease is transmitted
A)from parent to offspring via milk, ovum, sperm, or placenta.
B)from parent to offspring via respiratory route.
C)by contact between siblings.
D)between people living or working in the same building.
E)between higher and lower animals.
A)from parent to offspring via milk, ovum, sperm, or placenta.
B)from parent to offspring via respiratory route.
C)by contact between siblings.
D)between people living or working in the same building.
E)between higher and lower animals.
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59
A veterinary hospital had an outbreak of Salmonella infantis.Within the facility, how can Salmonella can be spread?
A)Unwashed hands
B)Feces
C)Contaminated objects
D)Multiple animals using the same stalls without proper cleaning
E)All of the choices are correct
A)Unwashed hands
B)Feces
C)Contaminated objects
D)Multiple animals using the same stalls without proper cleaning
E)All of the choices are correct
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60
Which portal of entry is the most commonly used by pathogens?
A)urogenital
B)gastrointestinal
C)respiratory
D)skin
E)They are all equally used as portals.
A)urogenital
B)gastrointestinal
C)respiratory
D)skin
E)They are all equally used as portals.
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61
_____ are toxins that are the lipopolysaccharide of the outer membrane of gram negative cell walls.
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62
_____ are a set of criteria used to identify and link a specific microorganism as the etiologic agent of a new infectious disease.
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63
Select 5 specific virulence factors and explain how each factor increases a pathogen's virulence.
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64
Leukopenia is the _____ in the level of white blood cells in a patient.
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65
Write about some ways to prevent any contamination in lab while making sub-cultures.
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66
Discuss 5 specific contributing factors in the occurrence of nosocomial infections, and then discuss 3 actions that can help decrease their rate at health-care facilities.
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67
The total number of deaths in a population due to a disease is the _____ rate.
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68
_____ is the presence of small numbers of bacteria in the blood.
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69
Describe the criteria that make up Koch's Postulates and discuss their importance in modern epidemiology.
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70
A _____ is an infection indigenous to animals that can, on occasion, be transmitted to humans.
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71
Compare and contrast exotoxins and endotoxins with regard to their: a) chemical nature, b) source, c) effects on human body cells and resulting symptoms, and d) examples.
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72
_____ are various bacterial enzymes that dissolve fibrin clots.
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73
_____ carriers are shedding and transmitting pathogen while they are recovering from an infectious disease.
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