Deck 41: Alterations of Digestive Function
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Deck 41: Alterations of Digestive Function
1
What term is used to identify frank bleeding of the rectum?
A) Melena
B) Hematochezia
C) Occult bleeding
D) Hematemesis
A) Melena
B) Hematochezia
C) Occult bleeding
D) Hematemesis
Hematochezia
2
What is the most immediate result of a small intestinal obstruction?
A) Vomiting
B) Dehydration
C) Electrolyte imbalances
D) Distention
A) Vomiting
B) Dehydration
C) Electrolyte imbalances
D) Distention
Distention
3
What is the cause of gastroesophageal reflux disease?
A) Excessive production of hydrochloric acid
B) Zone of low pressure of the lower esophageal sphincter
C) Presence of Helicobacter pylori in the esophagus
D) Reverse muscular peristalsis of the esophagus
A) Excessive production of hydrochloric acid
B) Zone of low pressure of the lower esophageal sphincter
C) Presence of Helicobacter pylori in the esophagus
D) Reverse muscular peristalsis of the esophagus
Zone of low pressure of the lower esophageal sphincter
4
Where in the brain is the vomiting center located?
A) Hypothalamus
B) Medulla oblongata
C) Pons
D) Midbrain
A) Hypothalamus
B) Medulla oblongata
C) Pons
D) Midbrain
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5
What type of diarrhea is a result of lactase deficiency?
A) Motility
B) Osmotic
C) Secretory
D) Small-volume
A) Motility
B) Osmotic
C) Secretory
D) Small-volume
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6
An intestinal obstruction at the pylorus or high in the small intestine causes metabolic alkalosis by causing which outcome?
A) Gain of bicarbonate from pancreatic secretions that cannot be absorbed
B) Excessive loss of hydrogen ions normally absorbed from gastric juices
C) Excessive loss of potassium, promoting atony of the intestinal wall
D) Loss of bile acid secretions that cannot be absorbed
A) Gain of bicarbonate from pancreatic secretions that cannot be absorbed
B) Excessive loss of hydrogen ions normally absorbed from gastric juices
C) Excessive loss of potassium, promoting atony of the intestinal wall
D) Loss of bile acid secretions that cannot be absorbed
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7
How can abdominal pain that is visceral in nature best be described?
A) Abdominal pain that is visceral in nature is diffused, vague, poorly localized, and dull.
B) It travels from a specific organ to the spinal cord.
C) The pain lateralizes from only one side of the nervous system.
D) Abdominal pain is associated with the peristalsis of the gastrointestinal tract.
A) Abdominal pain that is visceral in nature is diffused, vague, poorly localized, and dull.
B) It travels from a specific organ to the spinal cord.
C) The pain lateralizes from only one side of the nervous system.
D) Abdominal pain is associated with the peristalsis of the gastrointestinal tract.
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8
Considering the normal frequency of bowel evacuation,how infrequently can evacuation occur and still be considered within normal range?
A) Once a day
B) Once every 2 days
C) Once a week
D) Once every 2 weeks
A) Once a day
B) Once every 2 days
C) Once a week
D) Once every 2 weeks
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9
What are the cardinal symptoms of small intestinal obstruction?
A) Constant, dull pain in the lower abdomen relieved by defecation
B) Acute, intermittent pain 30 minutes to 2 hours after eating
C) Colicky pain caused by distention, followed by vomiting
D) Excruciating pain in the hypogastric area caused by ischemia
A) Constant, dull pain in the lower abdomen relieved by defecation
B) Acute, intermittent pain 30 minutes to 2 hours after eating
C) Colicky pain caused by distention, followed by vomiting
D) Excruciating pain in the hypogastric area caused by ischemia
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10
What type of vomiting is caused by the direct stimulation of the vomiting center by neurologic lesions involving the brainstem?
A) Retch
B) Periodic
C) Duodenal
D) Projectile
A) Retch
B) Periodic
C) Duodenal
D) Projectile
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11
What is a cause of chronic antral gastritis?
A) Helicobacter pylori bacteria
B) Development of autoantibodies to gastric H+/K+ ATPase
C) Pernicious anemia
D) Reflux of bile and alkaline pancreatic secretions
A) Helicobacter pylori bacteria
B) Development of autoantibodies to gastric H+/K+ ATPase
C) Pernicious anemia
D) Reflux of bile and alkaline pancreatic secretions
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12
What is the primary cause of peptic ulcers?
A) Hypersecretion of gastric acid
B) Hyposecretion of pepsin
C) Helicobacter pylori
D) Escherichia coli
A) Hypersecretion of gastric acid
B) Hyposecretion of pepsin
C) Helicobacter pylori
D) Escherichia coli
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13
A person who has cholera would be expected to have which type of diarrhea?
A) Osmotic
B) Secretory
C) Small volume
D) Motility
A) Osmotic
B) Secretory
C) Small volume
D) Motility
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14
What is the cause of reflux esophagitis?
A) Immune response to gastroesophageal reflux
B) Delayed gastric emptying
C) Congenital anomaly
D) Secretory response to gastroesophageal reflux
A) Immune response to gastroesophageal reflux
B) Delayed gastric emptying
C) Congenital anomaly
D) Secretory response to gastroesophageal reflux
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15
The adult intestine processes approximately how many liters of luminal content per day?
A) 3
B) 6
C) 9
D) 12
A) 3
B) 6
C) 9
D) 12
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16
How many stools per day are considered the upper limits of normal?
A) Two
B) Three
C) Five
D) Seven
A) Two
B) Three
C) Five
D) Seven
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17
By what mechanism does intussusception cause an intestinal obstruction?
A) Telescoping of part of the intestine into another section of intestine, usually causing strangulation of the blood supply
B) Twisting the intestine on its mesenteric pedicle, causing occlusion of the blood supply
C) Loss of peristaltic motor activity in the intestine, causing an adynamic ileus
D) Forming fibrin and scar tissue that attach to the intestinal omentum, causing obstruction
A) Telescoping of part of the intestine into another section of intestine, usually causing strangulation of the blood supply
B) Twisting the intestine on its mesenteric pedicle, causing occlusion of the blood supply
C) Loss of peristaltic motor activity in the intestine, causing an adynamic ileus
D) Forming fibrin and scar tissue that attach to the intestinal omentum, causing obstruction
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18
Which statement is false concerning how abdominal pain is produced?
A) Chemical mediators, such as histamine, bradykinin, and serotonin, produce abdominal pain.
B) Edema and vascular congestion produce abdominal pain by stretching.
C) Ischemia, caused by distention of bowel obstruction or mesenteric vessel thrombosis, produces abdominal pain.
D) Low concentrations of anaerobes, such as Streptococci, Lactobacilli, Staphylococci, Enterobacteria, and Bacteroides, produce abdominal pain.
A) Chemical mediators, such as histamine, bradykinin, and serotonin, produce abdominal pain.
B) Edema and vascular congestion produce abdominal pain by stretching.
C) Ischemia, caused by distention of bowel obstruction or mesenteric vessel thrombosis, produces abdominal pain.
D) Low concentrations of anaerobes, such as Streptococci, Lactobacilli, Staphylococci, Enterobacteria, and Bacteroides, produce abdominal pain.
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19
What is the cause of functional dysphagia?
A) Intrinsic mechanical obstruction
B) Extrinsic mechanical obstruction
C) Tumor
D) Neural or muscular disorders
A) Intrinsic mechanical obstruction
B) Extrinsic mechanical obstruction
C) Tumor
D) Neural or muscular disorders
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20
Antiemetic agents,such as domperidone and haloperidol,are antagonists for which receptors?
A) 5-Hydroxytryptamine (5-HT) serotonin
B) Histamine-2
C) Acetylcholine
D) Dopamine
A) 5-Hydroxytryptamine (5-HT) serotonin
B) Histamine-2
C) Acetylcholine
D) Dopamine
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21
Which symptom is characteristic of bulimia nervosa?
A) Recurrent episodes of binge eating with fears of not being able to stop eating.
B) Fear of becoming obese, despite progressive weight loss.
C) Perception that the body is fat when it is actually underweight.
D) Absence of three consecutive menstrual periods.
A) Recurrent episodes of binge eating with fears of not being able to stop eating.
B) Fear of becoming obese, despite progressive weight loss.
C) Perception that the body is fat when it is actually underweight.
D) Absence of three consecutive menstrual periods.
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22
After a partial gastrectomy or pyloroplasty,clinical manifestations that include increased pulse,hypotension,weakness,pallor,sweating,and dizziness are the results of which mechanism?
A) Anaphylactic reaction in which chemical mediators, such as histamine, prostaglandins, and leukotrienes, relax vascular smooth muscles, causing shock
B) Postoperative hemorrhage during which a large volume of blood is lost, causing hypotension with compensatory tachycardia
C) Concentrated bolus that moves from the stomach into the small intestine, causing hyperglycemia and resulting in polyuria and eventually hypovolemic shock
D) Rapid gastric emptying and the creation of a high osmotic gradient in the small intestine, causing a sudden shift of fluid from the blood vessels to the intestinal lumen
A) Anaphylactic reaction in which chemical mediators, such as histamine, prostaglandins, and leukotrienes, relax vascular smooth muscles, causing shock
B) Postoperative hemorrhage during which a large volume of blood is lost, causing hypotension with compensatory tachycardia
C) Concentrated bolus that moves from the stomach into the small intestine, causing hyperglycemia and resulting in polyuria and eventually hypovolemic shock
D) Rapid gastric emptying and the creation of a high osmotic gradient in the small intestine, causing a sudden shift of fluid from the blood vessels to the intestinal lumen
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23
Which statements are true regarding parietal pain? (Select all that apply.)
A) Parietal pain arises from the parietal peritoneum.
B) It is generally more localized than visceral pain.
C) Parietal pain is usually less intense than visceral pain.
D) Nerve fibers that travel to the spinal cord are involved in parietal pain.
E) Parietal pain corresponds to dermatomes T6 and L1.
A) Parietal pain arises from the parietal peritoneum.
B) It is generally more localized than visceral pain.
C) Parietal pain is usually less intense than visceral pain.
D) Nerve fibers that travel to the spinal cord are involved in parietal pain.
E) Parietal pain corresponds to dermatomes T6 and L1.
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24
A peptic ulcer may occur in all of the following areas except the:
A) Stomach
B) Duodenum
C) Jejunum
D) Esophagus
A) Stomach
B) Duodenum
C) Jejunum
D) Esophagus
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25
Which statement is consistent with dumping syndrome?
A) Dumping syndrome usually responds well to dietary management.
B) It occurs 1 to 2 hours after eating.
C) Constipation is often a result of the dumping syndrome.
D) It can result in alkaline reflux gastritis.
A) Dumping syndrome usually responds well to dietary management.
B) It occurs 1 to 2 hours after eating.
C) Constipation is often a result of the dumping syndrome.
D) It can result in alkaline reflux gastritis.
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26
Which statement is false concerning the pathophysiologic process of alcoholic cirrhosis?
A) Inflammation and damage leading to cirrhosis begin in the bile canaliculi.
B) Alcohol is transformed to acetaldehyde, which promotes liver fibrosis.
C) Mitochondrial function is impaired, decreasing oxidation of fatty acids.
D) Acetaldehyde inhibits export of proteins from the liver.
A) Inflammation and damage leading to cirrhosis begin in the bile canaliculi.
B) Alcohol is transformed to acetaldehyde, which promotes liver fibrosis.
C) Mitochondrial function is impaired, decreasing oxidation of fatty acids.
D) Acetaldehyde inhibits export of proteins from the liver.
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27
The most common clinical manifestation of portal hypertension is what type of bleeding?
A) Rectal
B) Duodenal
C) Esophageal
D) Intestinal
A) Rectal
B) Duodenal
C) Esophageal
D) Intestinal
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28
The mutation of which gene is an early event associated with the pathogenetic origin of esophageal cancer?
A) K-ras mutation
B) TP53
C) myc
D) HER2
A) K-ras mutation
B) TP53
C) myc
D) HER2
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29
Which statement is false concerning the accumulation of fluid in the peritoneal cavity?
A) Impaired excretion of sodium by the kidneys promotes water retention.
B) Decreased oncotic pressure and increased hepatic sinusoidal hydrostatic pressure cause the movement of fluid into the peritoneal cavity.
C) Decreased blood flow to the kidneys activates aldosterone, which retains sodium.
D) Circulating nitric oxide causes vasoconstriction, which forces fluid from the capillaries into the peritoneal cavity.
A) Impaired excretion of sodium by the kidneys promotes water retention.
B) Decreased oncotic pressure and increased hepatic sinusoidal hydrostatic pressure cause the movement of fluid into the peritoneal cavity.
C) Decreased blood flow to the kidneys activates aldosterone, which retains sodium.
D) Circulating nitric oxide causes vasoconstriction, which forces fluid from the capillaries into the peritoneal cavity.
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30
What is the most common manifestation of portal hypertension-induced splenomegaly?
A) Leukopenia
B) Thrombocytopenia
C) Erythrocytopenia
D) Pancytopenia
A) Leukopenia
B) Thrombocytopenia
C) Erythrocytopenia
D) Pancytopenia
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31
Which statements are true regarding chronic gastritis? (Select all that apply.)
A) Chronic gastritis tends to occur in older adults.
B) It causes thinning and degeneration of the stomach wall.
C) Chronic gastritis results in chronic inflammation and mucosal atrophy.
D) Mucosal atrophy is a common outcome of chronic gastritis.
E) Epithelial metaplasia is often observed with chronic gastritis.
A) Chronic gastritis tends to occur in older adults.
B) It causes thinning and degeneration of the stomach wall.
C) Chronic gastritis results in chronic inflammation and mucosal atrophy.
D) Mucosal atrophy is a common outcome of chronic gastritis.
E) Epithelial metaplasia is often observed with chronic gastritis.
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32
Hepatic fat accumulation is observed in which form of cirrhosis?
A) Biliary
B) Metabolic
C) Postnecrotic
D) Alcoholic
A) Biliary
B) Metabolic
C) Postnecrotic
D) Alcoholic
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33
Which statement is false regarding the pathophysiologic process of acute pancreatitis?
A) Bile duct or pancreatic duct obstruction blocks the outflow of pancreatic digestive enzymes.
B) Acute pancreatitis can also result from direct cellular injury from drugs or viral infection.
C) Acute pancreatitis is an autoimmune disease in which immunoglobulin G (IgG) coats the pancreatic acinar cells; consequently, the pancreatic enzymes destroy the cells.
D) Acute pancreatitis is usually mild and spontaneously resolves.
A) Bile duct or pancreatic duct obstruction blocks the outflow of pancreatic digestive enzymes.
B) Acute pancreatitis can also result from direct cellular injury from drugs or viral infection.
C) Acute pancreatitis is an autoimmune disease in which immunoglobulin G (IgG) coats the pancreatic acinar cells; consequently, the pancreatic enzymes destroy the cells.
D) Acute pancreatitis is usually mild and spontaneously resolves.
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34
Which structure regulates eating behavior and energy metabolism?
A) Anterior pituitary
B) Hypothalamus
C) Posterior pituitary
D) Parietal lobe
A) Anterior pituitary
B) Hypothalamus
C) Posterior pituitary
D) Parietal lobe
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35
Which hormones are natural appetite suppressants? (Select all that apply.)
A) Insulin
B) Cortisol
C) Galanin
D) Calcitonin
E) Serotonin
A) Insulin
B) Cortisol
C) Galanin
D) Calcitonin
E) Serotonin
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36
Which statement is false regarding the contributing factors of duodenal ulcers?
A) Bleeding from duodenal ulcers causes hematemesis or melena.
B) Gastric emptying is slowed, causing greater exposure of the mucosa to acid.
C) The characteristic pain begins 30 minutes to 2 hours after eating when the stomach is empty.
D) Duodenal ulcers occur with greater frequency than other types of peptic ulcers.
A) Bleeding from duodenal ulcers causes hematemesis or melena.
B) Gastric emptying is slowed, causing greater exposure of the mucosa to acid.
C) The characteristic pain begins 30 minutes to 2 hours after eating when the stomach is empty.
D) Duodenal ulcers occur with greater frequency than other types of peptic ulcers.
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37
Which are the early (prodromal)clinical manifestations of hepatitis? (Select all that apply.)
A) Fatigue
B) Vomiting
C) Itching
D) Splenomegaly
E) Hyperalgia
A) Fatigue
B) Vomiting
C) Itching
D) Splenomegaly
E) Hyperalgia
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38
Obesity is defined as a body mass index (BMI)greater than what measurement?
A) 22
B) 25
C) 28
D) 30
A) 22
B) 25
C) 28
D) 30
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39
What stimulates the desire to eat?
A) Agouti-related protein (AgRP)
B) Alpha-melanocyte-stimulating hormone (a-MSH)
C) Cocaine- and amphetamine-regulated transcript (CART)
D) Peptide YY (PYY)
A) Agouti-related protein (AgRP)
B) Alpha-melanocyte-stimulating hormone (a-MSH)
C) Cocaine- and amphetamine-regulated transcript (CART)
D) Peptide YY (PYY)
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40
Which statement is false regarding the sources of increased ammonia that contribute to hepatic encephalopathy?
A) End products of intestinal protein digestion are sources of increased ammonia.
B) Digested blood leaking from ruptured varices is a source of increased ammonia.
C) Accumulation of short-chain fatty acids that is attached to ammonia is a source of increased ammonia.
D) Ammonia-forming bacteria in the colon are sources of increased ammonia.
A) End products of intestinal protein digestion are sources of increased ammonia.
B) Digested blood leaking from ruptured varices is a source of increased ammonia.
C) Accumulation of short-chain fatty acids that is attached to ammonia is a source of increased ammonia.
D) Ammonia-forming bacteria in the colon are sources of increased ammonia.
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41
Which clinical manifestations are consistent with cancer of the cecum and ascending colon? (Select all that apply.)
A) Mahogany-colored blood mixed with stool
B) Anemia
C) Pain
D) Constipation
E) Palpable mass in the lower right quadrant
A) Mahogany-colored blood mixed with stool
B) Anemia
C) Pain
D) Constipation
E) Palpable mass in the lower right quadrant
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42
Match the descriptions with the corresponding terms.
Alterations in immunoglobulin G (IgA)production have been found in individuals with this disorder.
A)Ulcerative colitis
B)Crohn disease
Alterations in immunoglobulin G (IgA)production have been found in individuals with this disorder.
A)Ulcerative colitis
B)Crohn disease
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43
Match the descriptions with the corresponding terms.
Inflammation develops in crypts of Lieberkühn in the large intestine.
A)Ulcerative colitis
B)Crohn disease
Inflammation develops in crypts of Lieberkühn in the large intestine.
A)Ulcerative colitis
B)Crohn disease
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