Deck 3: Proteins
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Deck 3: Proteins
1
The fundamental physical and functional unit of inheritance that encodes a functional product is a:
A) Gene
B) Protein
C) Nucleotide
D) Nucleic acid
A) Gene
B) Protein
C) Nucleotide
D) Nucleic acid
Gene
2
Which of the following amino acids has a nonpolar R group?
A) Valine
B) Cysteine
C) Serine
D) Tyrosine
A) Valine
B) Cysteine
C) Serine
D) Tyrosine
Valine
3
Which of the following describes the general structure of an amino acid?
A) Planar carbon-nitrogen ring with deoxyribose sugar
B) Pentose sugar bound to phosphate and purine or pyrimidine base
C) Central carbon with carboxyl group, amino group, hydrogen, and a side chain
D) Polymer of molecules bound together by a peptide bond
A) Planar carbon-nitrogen ring with deoxyribose sugar
B) Pentose sugar bound to phosphate and purine or pyrimidine base
C) Central carbon with carboxyl group, amino group, hydrogen, and a side chain
D) Polymer of molecules bound together by a peptide bond
Central carbon with carboxyl group, amino group, hydrogen, and a side chain
4
Denaturation of a protein results in what effect?
A) Activation of protein activity
B) Loss of tertiary structure and protein function
C) None
D) Alteration of the amino acid sequence
A) Activation of protein activity
B) Loss of tertiary structure and protein function
C) None
D) Alteration of the amino acid sequence
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5
The codons that do not code for an amino acid and terminate protein synthesis are what kind of codon?
A) Wobble
B) Initiation
C) Nonsense
D) Anticodon
A) Wobble
B) Initiation
C) Nonsense
D) Anticodon
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6
What chemical group is found at the end of peptide chains?
A) Carboxyl
B) Hydroxyl
C) Phosphate
D) Amine
A) Carboxyl
B) Hydroxyl
C) Phosphate
D) Amine
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7
What chemical group is found at the beginning of peptide chains?
A) Carboxyl
B) Hydroxyl
C) Phosphate
D) Amine
A) Carboxyl
B) Hydroxyl
C) Phosphate
D) Amine
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8
A codon consists of a sequence of how many nucleotides?
A) One
B) Two
C) Three
D) Four
A) One
B) Two
C) Three
D) Four
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9
A protein that has lost its tertiary structure is called:
A) A zwitterion
B) A zinc finger
C) Denatured
D) Depolymerized
A) A zwitterion
B) A zinc finger
C) Denatured
D) Depolymerized
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10
The set of nucleotides in mRNA that encode one amino acid is called a(n):
A) Codon
B) Gene
C) Anticodon
D) Chromosome
A) Codon
B) Gene
C) Anticodon
D) Chromosome
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11
The sequence of amino acids in a protein constitutes which level of protein structure?
A) Primary
B) Secondary
C) Tertiary
D) Quaternary
A) Primary
B) Secondary
C) Tertiary
D) Quaternary
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12
Alpha helices and beta-pleated sheets are what level of protein structure?
A) Primary
B) Secondary
C) Tertiary
D) Quaternary
A) Primary
B) Secondary
C) Tertiary
D) Quaternary
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13
What enzymes are important for faithful translation of genetic information from RNA to protein?
A) DNA polymerase
B) Amino-acyl tRNA synthetase
C) DNA ligase
D) Exonuclease
A) DNA polymerase
B) Amino-acyl tRNA synthetase
C) DNA ligase
D) Exonuclease
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14
All but two amino acids are encoded by more than one codon, thus making the genetic code:
A) Error-prone
B) Random
C) Redundant
D) Denatured
A) Error-prone
B) Random
C) Redundant
D) Denatured
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15
Protein structure characterized by the combination of different proteins that all together are required for protein function is which level of protein structure?
A) Primary
B) Secondary
C) Tertiary
D) Quaternary
A) Primary
B) Secondary
C) Tertiary
D) Quaternary
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16
The chemical nature of alanine, leucine, phenylalanine, and tryptophan is described as:
A) Polar
B) Acidic
C) Basic
D) Nonpolar
A) Polar
B) Acidic
C) Basic
D) Nonpolar
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17
The process of protein synthesis is also called:
A) Translation
B) Transcription
C) Transduction
D) Transformation
A) Translation
B) Transcription
C) Transduction
D) Transformation
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18
At physiological pH, amino acids are:
A) Anions
B) Cations
C) Neutral
D) Zwitterions
A) Anions
B) Cations
C) Neutral
D) Zwitterions
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19
In translation, what is the starting material, the ending material, and the major enzyme that catalyzes the process?
A) DNA, RNA, DNA polymerase
B) RNA, protein, peptidyl transferase
C) RNA, DNA, reverse transcriptase
D) DNA, RNA, RNA polymerase
A) DNA, RNA, DNA polymerase
B) RNA, protein, peptidyl transferase
C) RNA, DNA, reverse transcriptase
D) DNA, RNA, RNA polymerase
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20
In early experiments, a polymer of uracil, UUUUUUUU…, translated into a peptide comprising only phenylalanine amino acids. What did this observation demonstrate?
A) Uracil is not a functional nucleotide.
B) UUU codes for phenylalanine.
C) RNA cannot be faithfully translated in vitro.
D) No other amino acid codon contains uracil.
A) Uracil is not a functional nucleotide.
B) UUU codes for phenylalanine.
C) RNA cannot be faithfully translated in vitro.
D) No other amino acid codon contains uracil.
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21
ER stress stops protein synthesis in response to what?
A) Unfolded proteins
B) Cell division
C) Amino acids
D) Degraded RNA
A) Unfolded proteins
B) Cell division
C) Amino acids
D) Degraded RNA
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22
What amino acid is used to initiate most proteins in eukaryotes?
A) Methionine
B) Alanine
C) Proline
D) Aminoacyl tRNA synthetase
A) Methionine
B) Alanine
C) Proline
D) Aminoacyl tRNA synthetase
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23
In the ribosome, the growing peptide moves from site to site in what direction?
A) A to E to P
B) P to A to E
C) E to P to A
D) A to P to E
A) A to E to P
B) P to A to E
C) E to P to A
D) A to P to E
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24
Specialized proteins that bind to the large ribosomal subunit and protect the hydrophobic regions of growing polypeptides are called:
A) Aminoacyl tRNA synthetases
B) Molecular chaperones
C) Metalloproteins
D) Peptidyl transferases
A) Aminoacyl tRNA synthetases
B) Molecular chaperones
C) Metalloproteins
D) Peptidyl transferases
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25
A glycoprotein contains ______attached after translation.
A) extra amino acids
B) sugar moieties
C) lipids
D) metal ions
A) extra amino acids
B) sugar moieties
C) lipids
D) metal ions
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26
The enzyme that bonds two amino acids together in protein synthesis is:
A) Peptidyl transferase
B) Protein synthetase
C) Amino acid polymerase
D) Aminoacyl tRNA synthetase
A) Peptidyl transferase
B) Protein synthetase
C) Amino acid polymerase
D) Aminoacyl tRNA synthetase
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27
Given the following sequence of mRNA, what is the corresponding amino acid sequence? 5AUGCAUAACUCUGCU3
A) DCITL
B) RHNSA
C) AQRRV
D) MHNSA
A) DCITL
B) RHNSA
C) AQRRV
D) MHNSA
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28
The start codon for synthesis of most proteins is:
A) ACC
B) UGA
C) AUG
D) UAA
A) ACC
B) UGA
C) AUG
D) UAA
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29
The collection of proteins produced by a genome is called the:
A) Proteome
B) Protease
C) Ribosome
D) Genetic code
A) Proteome
B) Protease
C) Ribosome
D) Genetic code
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30
Hydrolysis of the finished polypeptide from the final tRNA by release factors would occur at which of the following codons?
A) AUG
B) GUG
C) ACC
D) UGA
A) AUG
B) GUG
C) ACC
D) UGA
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