Deck 2: From Hematopoiesis to the Complete Blood Count

Question 1

The hormone responsible for red blood cell development in the bone marrow is:

A) Thyroxin
B) Insulin
C) Leukopoietin
D) Erythropoietin

Answer 1

D

Question 2

Patients with moderate anemias (7 to 10 g/dL) may be asymptomatic.

Answer 2

True

Question 3

What is the average M:E ratio for normal adult bone marrow?

A) 1:3
B) 4:1
C) 1:4
D) 6:1

Answer 3

B

Question 4

A patient with the following values-RBC = 4.01  10¹²/L, Hgb = 12.5 g/dL, and Hct = 37.2%-will most likely have which of the following RBC indices?

A) MCV = 92.8 fL, MCH = 31.2 pg, MCHC = 33.6%
B) MCV = 92.8 fL, MCH = 33.6 pg, MCHC = 31.2%
C) MCV = 107.8 fL, MCH = 32.1 pg, MCHC = 33.6%
D) MCV = 132.2 fL, MCH = 32.1 pg, MCHC = 33.5%

Question 5

The spleen harbors _of the circulatory platelet mass.

A) one-quarter
B) one-third
C) one-half
D) three-quarters

Question 6

The __is one of the most stable parameters in a CBC.

A) MCV
B) Hct
C) MCHC
D) MCH

Question 7

The key organs involved in extramedullary hematopoiesis include the:

A) Kidney and thymus
B) Lymph nodes and heart
C) Liver and spleen
D) Kidney and liver

Question 8

T cells are responsible for humoral immunity.

Question 9

A patient's hemoglobin is 12.3 g/dL.On the peripheral smear, the red cells appear normochromic, normocytic.The hematocrit value that correlates with these data is:

A) 34%
B) 37%
C) 40%
D) 43%

Question 10

A Wright-stained smear of a patient with an elevated reticulocyte count should show:

A) Polychromasia
B) Agglutination
C) Rouleaux
D) Microcytosis

Question 11

A peripheral blood smear indicator of ineffective bone marrow response is:

A) The presence of basophilic stippling
B) A lack of polychromasia
C) Higher numbers of nucleated red cells
D) An increased number of red cells

Question 12

Erythropoietin is produced by the:

A) Kidneys
B) Liver
C) Spleen
D) Thymus gland

Question 13

The CBC parameter that gives insight as to the amount of anisocytosis present in a specimen is:

A) RDW
B) MCHC
C) MCV
D) Hgb

Question 14

Correlation checks between the red blood cell count, the hemoglobin, and the hematocrit are significant parts of QA (quality assurance) in the hematology lab.These correlations are known as:

A) Delta checks
B) The rules of three
C) Quality control
D) Analytical variables

Question 15

Which of the following sites is the most preferable site for bone marrow aspiration and biopsy in adults?

A) Sternum
B) Iliac crest
C) Fibula
D) Vertebra

Question 16

Antibody-coated red cells that have their antibodies stripped away in the spleen usually reappear in the circulation as:

A) Spherocytes
B) Microcytes
C) Acanthocytes
D) Burr cells

Question 17

Which of these assays is the best test to assess the bone marrow's response to anemic stress?

A) Hemoglobin value
B) MCV value
C) Reticulocyte count
D) Hematocrit

Question 18

Mature red blood cells leave the bone marrow and enter the circulation via the:

A) Reticuloendothelial system
B) Osteoclasts
C) Spleen
D) Bone marrow sinuses

Question 19

Bone marrow aspiration is usually required in conditions of:

A) Anemia
B) Hypoxia
C) Leukemia
D) Hepatosplenomegaly

Question 20

Opsonizing antibodies produced by the spleen serve to:

A) Strip the capsule from bacterial pathogens
B) Recycle erythrocyte byproducts
C) Aid in extramedullary hematopoiesis
D) Fight viral infection