Deck 15: Psychedelic Drugs

Question 1

Based on your basic knowledge of the nervous system,you would conclude that anticholinergics affect pupil size via the:

A)skeletal nervous system.
B)sympathetic nervous system.
C)parasympathetic nervous system.
D)central nervous system.

Answer 1

C

Question 2

Which of the following statements is true concerning the chronic use of LSD?

A)Both tolerance to and physical dependence develops.
B)Neither tolerance to nor physical dependence develops.
C)Tolerance,but not physical dependence,develops.
D)Physical dependence,but not tolerance,develops.

Answer 2

C

Question 3

The anticholinergic psychedelics ________ pupil size and ________ heart rate,respectively.

A)increase; increase
B)decrease; decrease
C)increase; decrease
D)decrease; increase

Answer 3

A

Question 4

Psilocybin and psilocin have their major effect on the ________ neurotransmitter.

A)acetylcholine
B)norepinephrine
C)dopamine
D)serotonin

Question 5

The anticholinergics ________ sensory perception and ________ memory,respectively.

A)expand; facilitate
B)expand; impair
C)cloud; facilitate
D)cloud; impair

Question 6

LSD is perceived to ________ time and ________sensory perception,respectively:

A)slow; enhance
B)slow; impair
C)accelerate; enhance
D)accelerate; impair

Question 7

Which of the following statements is true concerning the chronic use of LSD?

A)Both tolerance and cross-tolerance to the psychedelics develop.
B)Neither tolerance nor cross-tolerance to the psychedelics develops.
C)Tolerance,but not cross-tolerance to other psychedelics,develops.
D)Cross-tolerance to the psychedelics,but not tolerance,develops.

Question 8

The typical hallucination produced by the serotonin psychedelics is ________ in nature.

A)auditory
B)tactile
C)olfactory
D)visual

Question 9

The neurotransmitter affected by the psychedelic scopolamine is:

A)acetylcholine.
B)norepinephrine.
C)dopamine.
D)glutamate.

Question 10

Based on your knowledge of its actions,you might suspect that atropine is of use in surgery because of its ability to:

A)constrict pupils.
B)decrease blood pressure.
C)sharpen vision.
D)decrease salivation.

Question 11

As a pharmacologist developing a drug to reduce the effects of scopolamine,your most likely candidate is:

A)a serotonin agonist.
B)a serotonin antagonist.
C)an acetylcholine agonist.
D)an acetylcholine antagonist.

Question 12

The neurotransmitter responsible for muscle contraction is acetylcholine.The reason scopolamine doesn't affect muscle contraction is (Hint: Try the process of elimination):

A)scopolamine doesn't enter the CNS.
B)the central effects of scopolamine are opposite to its peripheral effects.
C)scopolamine doesn't affect the PNS.
D)the acetylcholine receptors on skeletal muscle are different than those in other areas of the

Question 13

The catecholaminelike psychedelics have major effects on the following neurotransmitters:

A)serotonin and GABA.
B)neurotransmitter and glutamate.
C)dopamine and acetylcholine.
D)serotonin and dopamine.

Question 14

At the synaptic level,scopolamine acts as a(n):

A)antagonist.
B)agonist.
C)reuptake blocker.
D)enzyme inhibitor.

Question 15

The typical hallucination produced by mescaline is

A)auditory.
B)tactile.
C)olfactory.
D)visual.

Question 16

In healthy subjects,mescaline produces a brain image characterized by a:

A)hypofrontal pattern.
B)hyperfrontal pattern.
C)hypocerebellar pattern.
D)hypercerebellar pattern.

Question 17

Psilocybin and psilocin are most similar to the psychedelic:

A)PCP.
B)mescaline.
C)scopolamine.
D)LSD.

Question 18

Hallucinogen persisting perception disorder refers to:

A)tolerance to psychedelics.
B)the type of hallucinations produced by LSD.
C)perceptual distortions produced by LSD.
D)flashbacks.

Question 19

The catecholaminelike psychedelics are best described as:

A)hallucinogens.
B)stimulants.
C)dissociative anesthetics.
D)psychostimulant hallucinogens.

Question 20

All of the following are catecholaminelike psychedelics,EXCEPT:

A)MDA.
B)MDE.
C)MDMA.
D)NMDA.

Question 21

The street name angel dust refers to the psychedelic:

A)LSD.
B)MDMA.
C)mescaline.
D)phencyclidine.

Question 22

The combination "party pill" (BZP and TFMPP)exerts:

A)hallucinogenlike effects.
B)amphetaminelike effects.
C)stimulant effects.
D)All of the answers are correct.

Question 23

The psychedelic whose action does not involve serotonin,dopamine,or acetylcholine neurons is:

A)ecstasy.
B)mescaline.
C)angel dust.
D)psilocybin.

Question 24

PCP and ketamine can be described as:

A)hallucinogens.
B)stimulants.
C)dissociative anesthetics.
D)psychostimulant hallucinogens.

Question 25

The psychedelic ketamine acts via the following mechanism:

A)reuptake blockade.
B)competitive receptor blockade.
C)noncompetitive receptor blockade.
D)enzyme inhibition.

Question 26

Which of the following statements is most likely TRUE?

A)Psilocybin produces schizophrenialike symptoms as well as HPPD (hallucinogen-persisting perceptual disorder).
B)Psilocybin produces schizophrenialike symptoms but not HPPD.
C)Psilocybin produces HPPD but not schizophrenialike symptoms.
D)Psilocybin produces neither HPPD nor schizophrenialike symptoms.

Question 27

Salvinorin A is a unique hallucinogen in that it acts on:

A)both serotonin and opiate receptors.
B)mu opiate receptors,but not serotonin receptors.
C)kappa opiate receptors,but not serotonin receptors.
D)neither opiate nor serotonin receptors.

Question 28

PCP acts at the following receptor:

A)norepinephrine.
B)NMDA.
C)serotonin.
D)acetylcholine.

Question 29

DMT,or dimethyltryptamine,produces effects most like:

A)LSD.
B)mescaline.
C)PCP.
D)NMDA.

Question 30

The psychedelic presently used in veterinary medicine as an anesthetic is most closely related to:

A)LSD.
B)mescaline.
C)atropine.
D)PCP.

Question 31

PCP and ketamine are:

A)structurally and functionally similar.
B)structurally but not functionally similar.
C)functionally but not structurally similar.
D)neither structurally nor functionally similar.

Question 32

Psilocybin is:

A)converted into psilocin and produces auditory hallucinations.
B)converted into psilocin and produces visual hallucinations.
C)produced from psilocin and produces auditory hallucinations.
D)produced from psilocin and produces visual hallucinations.

Question 33

The psychedelic effects of angel dust are a result of action on the neurotransmitter:

A)dopamine.
B)acetylcholine.
C)serotonin.
D)glutamate.

Question 34

Scopolamine expands sensory perception.

Question 35

As a pharmacologist developing a drug to reduce the effects of PCP,your most likely candidate is a:

A)serotonin agonist.
B)serotonin antagonist.
C)glutamate agonist.
D)glutamate antagonist.

Question 36

The MDMA-like combination "party pill" (comprised of BZP and TFMPP)alters levels of:

A)NE
B)5-HT
C)DA
D)All of the answers are correct.

Question 37

The psychedelic producing overt intoxicating effects likened to ethanol is:

A)LSD.
B)mescaline.
C)scopolamine.
D)PCP.

Question 38

Recent evidence suggests that EtOH acts as a noncompetitive antagonist of the NMDA receptor.As such,it most closely resembles the action of the psychedelic:

A)ecstasy.
B)mescaline.
C)scopolamine.
D)angel dust.

Question 39

PCP induces:

A)an acute psychosis in normal subjects and exacerbates psychotic symptoms.
B)an acute psychosis in normal subjects but does not exacerbate psychotic symptoms.
C)a nonpsychotic state in normal subjects but exacerbates psychotic symptoms.
D)a nonpsychotic state in normal subjects and does not exacerbate psychotic symptoms.

Question 40

The psychedelic concomitantly producing intense analgesia is:

A)LSD.
B)mescaline.
C)scopolamine.
D)PCP.

Question 41

There is no evidence that MDMA (ecstasy)is neurotoxic.

Question 42

PCP is still used in veterinary medicine.

Question 43

Serotoninlike psychedelics intensify sensory perception.

Question 44

The psychedelic properties of the catecholaminelike psychedelics result from action on dopamine receptors.

Question 45

The NMDA receptor has been linked to schizophrenia.

Question 46

Physical dependence on LSD does not develop.

Question 47

Tolerance to LSD does not develop.

Question 48

PCP produces marked amnesia.

Question 49

PCP and ketamine do not act on either acetylcholine or dopamine neurons.

Question 50

LSD possesses a high level of toxicity.

Question 51

There is no evidence that PCP and ketamine act on 5-HT neurons.