Deck 21: Nucleic Acids and Protein Synthesis
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Deck 21: Nucleic Acids and Protein Synthesis
1
The base sequence of the strand of DNA complementary to the segment 5'-T-G-G-C-A-A-C-3' is:
A) 3'-T-G-G-C-A-A-C-5'
B) 3'-A-C-C-G-T-T-G-5'
C) 3'-A-C-C-G-U-U-G-5'
D) 3'-U-C-C-G-T-T-G-5'
E) 3'-A-C-G-C-T-U-G-5'
A) 3'-T-G-G-C-A-A-C-5'
B) 3'-A-C-C-G-T-T-G-5'
C) 3'-A-C-C-G-U-U-G-5'
D) 3'-U-C-C-G-T-T-G-5'
E) 3'-A-C-G-C-T-U-G-5'
3'-A-C-C-G-T-T-G-5'
2
What is the process in which the DNA double helix unfolds, and each strand serves as a template for the synthesis of a new strand?
A) transcription
B) complementation
C) translation
D) replication
E) restriction
A) transcription
B) complementation
C) translation
D) replication
E) restriction
replication
3
When DNA replicates, a guanine forms a base pair with
A) uracil.
B) adenine.
C) guanine.
D) thymine.
E) cytosine.
A) uracil.
B) adenine.
C) guanine.
D) thymine.
E) cytosine.
cytosine.
4
Which of the following is found in RNA but not in DNA?
A) thymine
B) uracil
C) guanine
D) cytosine
E) deoxyribose
A) thymine
B) uracil
C) guanine
D) cytosine
E) deoxyribose
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5
A __________ consists of a nitrogen-containing base, a sugar, and a phosphate group.
A) nucleoside
B) base pair
C) nucleotide
D) complementary base
E) purine
A) nucleoside
B) base pair
C) nucleotide
D) complementary base
E) purine
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6
The bonds that link the base pairs in the DNA double helix are
A) ionic bonds.
B) peptide bonds.
C) hydrogen bonds.
D) hydrophobic bonds.
E) ester bonds.
A) ionic bonds.
B) peptide bonds.
C) hydrogen bonds.
D) hydrophobic bonds.
E) ester bonds.
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7
When DNA duplicates itself, the correct placement of the nucleotides is accomplished by
A) complementary base pairing.
B) polymerase.
C) enzyme matching.
D) base matching.
E) transcription.
A) complementary base pairing.
B) polymerase.
C) enzyme matching.
D) base matching.
E) transcription.
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8
Which one of the following base pairs is found in DNA?
A) adenine-thymine
B) adenine-guanine
C) cytosine-thymine
D) adenine-uracil
E) guanine-uracil
A) adenine-thymine
B) adenine-guanine
C) cytosine-thymine
D) adenine-uracil
E) guanine-uracil
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9
The nucleotides in the backbone of DNA are held together by __________ bonds.
A) hydrogen
B) peptide
C) phosphodiester
D) glycosidic
E) ionic
A) hydrogen
B) peptide
C) phosphodiester
D) glycosidic
E) ionic
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10
Which of the following can NOT be found in a nucleotide of RNA?
A) purine
B) pyrimidine
C) phosphate
D) ribose
E) deoxyribose
A) purine
B) pyrimidine
C) phosphate
D) ribose
E) deoxyribose
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11
The two new DNA molecules formed in replication
A) are complementary to the original DNA.
B) both contain only two new daughter DNA strands.
C) both contain only the parent DNA strands.
D) contain one parent and one daughter strand.
E) are identical, with one containing both parent strands, and the other containing both daughter strands.
A) are complementary to the original DNA.
B) both contain only two new daughter DNA strands.
C) both contain only the parent DNA strands.
D) contain one parent and one daughter strand.
E) are identical, with one containing both parent strands, and the other containing both daughter strands.
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12
Which of the following types of RNA carries the genetic information from DNA in the nucleus to the cytoplasm for protein synthesis?
A) mRNA
B) histone RNA
C) rRNA
D) tRNA
E) sRNA
A) mRNA
B) histone RNA
C) rRNA
D) tRNA
E) sRNA
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13
Which of the following is NOT a step in DNA replication?
A) Hydrogen bonds break, allowing the two DNA strands to separate completely.
B) A base on the DNA pairs with its complementary base free in solution.
C) DNA polymerase forms bonds between a 5'-phosphate of one nucleotide and a 3'-hydroxyl of another.
D) On one strand the DNA is synthesized continuously.
E) DNA ligase connects short segments of DNA on one strand.
A) Hydrogen bonds break, allowing the two DNA strands to separate completely.
B) A base on the DNA pairs with its complementary base free in solution.
C) DNA polymerase forms bonds between a 5'-phosphate of one nucleotide and a 3'-hydroxyl of another.
D) On one strand the DNA is synthesized continuously.
E) DNA ligase connects short segments of DNA on one strand.
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14
A __________ consists of a nitrogen-containing base and a sugar.
A) nucleoside
B) base pair
C) nucleotide
D) complementary base
E) pyrimidine
A) nucleoside
B) base pair
C) nucleotide
D) complementary base
E) pyrimidine
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15
The two strands of the double helix of DNA are held together by
A) hydrogen bonds.
B) covalent bonds.
C) dipole-dipole interactions.
D) ionic bonds.
E) sugar-to-phosphate bonds.
A) hydrogen bonds.
B) covalent bonds.
C) dipole-dipole interactions.
D) ionic bonds.
E) sugar-to-phosphate bonds.
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16
Guanine is one example of a nitrogen base that is a
A) cofactor.
B) 5-carbon sugar.
C) phosphodiester.
D) pyrimidine.
E) purine.
A) cofactor.
B) 5-carbon sugar.
C) phosphodiester.
D) pyrimidine.
E) purine.
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17
Which of the following statements is TRUE?
A) Cytosine and Thymine are a complementary base pair that forms 3 hydrogen bonds.
B) Thymine and Guanine are a complementary base pair that forms 3 hydrogen bonds.
C) Cytosine and Guanine are a complementary base pair that forms 2 hydrogen bonds.
D) Thymine and Adenine are a complementary base pair that forms 2 hydrogen bonds.
E) Thymine and Guanine are a complementary base pair that forms 2 hydrogen bonds.
A) Cytosine and Thymine are a complementary base pair that forms 3 hydrogen bonds.
B) Thymine and Guanine are a complementary base pair that forms 3 hydrogen bonds.
C) Cytosine and Guanine are a complementary base pair that forms 2 hydrogen bonds.
D) Thymine and Adenine are a complementary base pair that forms 2 hydrogen bonds.
E) Thymine and Guanine are a complementary base pair that forms 2 hydrogen bonds.
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18
Which of the following hold two strands of DNA in an a helix?
A) ester linkages
B) disulfide linkages
C) peptide bonds
D) hydrogen bonds
E) glycosidic linkages
A) ester linkages
B) disulfide linkages
C) peptide bonds
D) hydrogen bonds
E) glycosidic linkages
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19
Which of the following can be found in DNA?
A) ribose
B) GMP
C) uracil
D) deoxyadenosine
E) FMN
A) ribose
B) GMP
C) uracil
D) deoxyadenosine
E) FMN
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20
Which of the following will not be found in DNA?
A) adenine
B) thymine
C) guanine
D) cytosine
E) ribose
A) adenine
B) thymine
C) guanine
D) cytosine
E) ribose
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21
When a mutation occurs by elimination of one base in a DNA sequence, this mutation is called a
A) frameshift mutation.
B) retrovirus insertion.
C) substitution mutation.
D) translocation mutation.
E) viral mutation.
A) frameshift mutation.
B) retrovirus insertion.
C) substitution mutation.
D) translocation mutation.
E) viral mutation.
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22
In transcription
A) the mRNA produced is identical to the parent DNA.
B) a double helix containing one parent strand and one daughter strand is produced.
C) uracil pairs with thymine.
D) both strands of the DNA are copied.
E) the mRNA produced is complementary to one strand of the DNA.
A) the mRNA produced is identical to the parent DNA.
B) a double helix containing one parent strand and one daughter strand is produced.
C) uracil pairs with thymine.
D) both strands of the DNA are copied.
E) the mRNA produced is complementary to one strand of the DNA.
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23
When mRNA is synthesized using the information from DNA, the process is called
A) transportation.
B) transposition.
C) transcription.
D) translation.
E) transliteration.
A) transportation.
B) transposition.
C) transcription.
D) translation.
E) transliteration.
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24
Which of the following is not a step in protein synthesis?
A) activation of tRNA
B) initiation
C) elongation
D) termination
E) unwinding of two strands of mRNA
A) activation of tRNA
B) initiation
C) elongation
D) termination
E) unwinding of two strands of mRNA
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25
The codon is found on __________, and the anticodon is found on __________.
A) mRNA; tRNA
B) tRNA; mRNA
C) rRNA; tRNA
D) ribosomes; tRNA
E) mRNA; rRNA
A) mRNA; tRNA
B) tRNA; mRNA
C) rRNA; tRNA
D) ribosomes; tRNA
E) mRNA; rRNA
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26
Mutations are the result of
A) alterations in the phosphate of the DNA backbone.
B) exposure to water in utero.
C) physical trauma in the mother's childhood.
D) alterations in the sugar component of the DNA backbone.
E) alterations in the DNA base sequence.
A) alterations in the phosphate of the DNA backbone.
B) exposure to water in utero.
C) physical trauma in the mother's childhood.
D) alterations in the sugar component of the DNA backbone.
E) alterations in the DNA base sequence.
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27
During protein synthesis, the codon for an amino acid is found on
A) DNA.
B) rRNA.
C) tRNA.
D) mRNA.
E) sRNA.
A) DNA.
B) rRNA.
C) tRNA.
D) mRNA.
E) sRNA.
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28
Some sections of a DNA molecule do not code for protein synthesis. These segments are called
A) codons.
B) anticodons.
C) Okazaki fragments.
D) introns.
E) exons.
A) codons.
B) anticodons.
C) Okazaki fragments.
D) introns.
E) exons.
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29
A tRNA is activated when it
A) attaches to mRNA.
B) attaches to its specific amino acid.
C) attaches to the ribosome.
D) leaves the ribosome.
E) releases its specific amino acid.
A) attaches to mRNA.
B) attaches to its specific amino acid.
C) attaches to the ribosome.
D) leaves the ribosome.
E) releases its specific amino acid.
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30
Which one of these base pairs is found in RNA?
A) guanine-cytosine
B) adenine-cytosine
C) adenine-thymine
D) adenine-guanine
E) guanine-thymine
A) guanine-cytosine
B) adenine-cytosine
C) adenine-thymine
D) adenine-guanine
E) guanine-thymine
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31
A DNA template having the base sequence 3'-A-G-A-T-G-A-5' would produce a mRNA with a base sequence of
A) 5'-A-G-A-T-G-A-3'.
B) 5'-U-C-U-A-C-U-3'.
C) 5'-T-C-T-U-C-T-3'.
D) 5'-T-C-T-A-C-A-3'.
E) 5'-A-C-A-U-C-A-3'.
A) 5'-A-G-A-T-G-A-3'.
B) 5'-U-C-U-A-C-U-3'.
C) 5'-T-C-T-U-C-T-3'.
D) 5'-T-C-T-A-C-A-3'.
E) 5'-A-C-A-U-C-A-3'.
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32
In the synthesis of mRNA, an adenine in the DNA pairs with
A) uracil.
B) adenine.
C) guanine.
D) thymine.
E) cytosine.
A) uracil.
B) adenine.
C) guanine.
D) thymine.
E) cytosine.
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33
In the enzyme induction model of cellular control,
A) cofactors control protein synthesis.
B) the substrate controls protein synthesis.
C) the substrate combines with a protein to form a repressor.
D) the enzyme for the substrate is always synthesized by the gene.
E) the substrate represses the operator.
A) cofactors control protein synthesis.
B) the substrate controls protein synthesis.
C) the substrate combines with a protein to form a repressor.
D) the enzyme for the substrate is always synthesized by the gene.
E) the substrate represses the operator.
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34
The anticodon of U-A-G is
A) A-T-C.
B) U-A-G.
C) A-A-C.
D) A-U-C.
E) G-A-U.
A) A-T-C.
B) U-A-G.
C) A-A-C.
D) A-U-C.
E) G-A-U.
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35
The result of a defective enzyme caused by a mutation in the DNA nucleotide sequence is
A) a genetic disease.
B) AIDS.
C) HIV.
D) recombinant DNA.
E) translocation.
A) a genetic disease.
B) AIDS.
C) HIV.
D) recombinant DNA.
E) translocation.
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36
The anticodon is
A) identical to the codon on DNA.
B) complementary to the codon on DNA.
C) identical to the codon on mRNA.
D) complementary to the codon on mRNA.
E) complementary to the codon on tRNA.
A) identical to the codon on DNA.
B) complementary to the codon on DNA.
C) identical to the codon on mRNA.
D) complementary to the codon on mRNA.
E) complementary to the codon on tRNA.
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37
Codons are base pair sequences that
A) signal the start of DNA synthesis.
B) signal the end of DNA synthesis.
C) code for amino acids.
D) signal the start of RNA synthesis.
E) code for one or more bases in mRNA.
A) signal the start of DNA synthesis.
B) signal the end of DNA synthesis.
C) code for amino acids.
D) signal the start of RNA synthesis.
E) code for one or more bases in mRNA.
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38
A set of directions in the DNA base sequence for the synthesis of a protein is a(n)
A) structural gene.
B) promotor.
C) operator.
D) codon.
E) regulatory gene.
A) structural gene.
B) promotor.
C) operator.
D) codon.
E) regulatory gene.
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39
Which of the following is a section of mRNA produced from the DNA template below? 3'-A-T-A-G-C-T-A-5'
A) 5'-A-T-A-G-C-T-A-3'
B) 5'-A-U-A-G-C-U-A-3'
C) 5'-U-A-U-C-G-A-U-3'
D) 5'-U-U-U-G-C-U-U-3'
E) 5'-T-A-T-C-G-A-T-3'
A) 5'-A-T-A-G-C-T-A-3'
B) 5'-A-U-A-G-C-U-A-3'
C) 5'-U-A-U-C-G-A-U-3'
D) 5'-U-U-U-G-C-U-U-3'
E) 5'-T-A-T-C-G-A-T-3'
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40
Translation is the process whereby
A) DNA is synthesized from DNA.
B) DNA is synthesized from mRNA.
C) protein is synthesized from DNA.
D) protein is synthesized from mRNA.
E) mRNA is synthesized from DNA.
A) DNA is synthesized from DNA.
B) DNA is synthesized from mRNA.
C) protein is synthesized from DNA.
D) protein is synthesized from mRNA.
E) mRNA is synthesized from DNA.
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41
Which of the following is used in the preparation of recombinant DNA?
A) RNA polymerase
B) DNA polymerase
C) repressor protein
D) restriction enzyme
E) enzyme induction
A) RNA polymerase
B) DNA polymerase
C) repressor protein
D) restriction enzyme
E) enzyme induction
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42
A virus that contains RNA as its genetic material is a
A) genetically engineered virus.
B) bacteria.
C) recombinant DNA.
D) retrovirus.
E) vaccine.
A) genetically engineered virus.
B) bacteria.
C) recombinant DNA.
D) retrovirus.
E) vaccine.
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43
Adenine is a purine.
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44
The polymerase chain reaction is used in
A) preparing recombinant DNA.
B) transcription.
C) DNA fingerprinting.
D) translation.
E) replication.
A) preparing recombinant DNA.
B) transcription.
C) DNA fingerprinting.
D) translation.
E) replication.
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45
The purpose of the human genome project was to
A) identify genes responsible for noninheritable diseases.
B) determine how to clone human DNA.
C) identify substrates for the polymerase chain reaction.
D) learn how to clone bacterial DNA.
E) map the locations of all the genes in human DNA.
A) identify genes responsible for noninheritable diseases.
B) determine how to clone human DNA.
C) identify substrates for the polymerase chain reaction.
D) learn how to clone bacterial DNA.
E) map the locations of all the genes in human DNA.
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46
Recombinant DNA technology requires the use of bacterial
A) plasmids.
B) mitochondria.
C) endoplasmic reticulum.
D) ribosomes.
E) cell walls.
A) plasmids.
B) mitochondria.
C) endoplasmic reticulum.
D) ribosomes.
E) cell walls.
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47
If the DNA double helix in humans contains 20% guanine, then the percent adenine is 30%.
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48
If the DNA double helix in humans contains 20% guanine, then the percent cytosine is 30%.
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49
The insertion of new DNA into the plasmid DNA of a bacterium produces
A) viral DNA.
B) DNA fingerprints.
C) recombinant DNA.
D) ribosomes.
E) restriction enzymes.
A) viral DNA.
B) DNA fingerprints.
C) recombinant DNA.
D) ribosomes.
E) restriction enzymes.
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50
In the DNA double helix, a purine can only bond with a pyrimidine.
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51
One therapeutic product now available due to recombinant DNA technology is
A) measles vaccine.
B) penicillin.
C) human growth hormone.
D) sulfamethoxazole.
E) tamoxifen.
A) measles vaccine.
B) penicillin.
C) human growth hormone.
D) sulfamethoxazole.
E) tamoxifen.
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52
DNA is a protein.
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53
DNA differs from RNA in the sugar it contains.
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54
A restriction enzyme functions to
A) prevent the DNA from leaving the nucleus.
B) limit the number of replications a DNA molecule can achieve.
C) cut a large DNA double helix into smaller fragments.
D) stop the elongation step of protein synthesis.
E) eliminate a virus from a cell.
A) prevent the DNA from leaving the nucleus.
B) limit the number of replications a DNA molecule can achieve.
C) cut a large DNA double helix into smaller fragments.
D) stop the elongation step of protein synthesis.
E) eliminate a virus from a cell.
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55
Small living particles, with 3 to 200 genes, that cannot replicate without a host cell are called
A) recombinant DNAs.
B) viruses.
C) bacteria.
D) tumors.
E) plasmids.
A) recombinant DNAs.
B) viruses.
C) bacteria.
D) tumors.
E) plasmids.
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56
DNA fingerprinting uses __________ to produce DNA fragments that can be separated and screened for the presence of genetic diseases.
A) extracellular DNA
B) restriction enzymes
C) bacterial plasmids
D) anticodons
E) codons
A) extracellular DNA
B) restriction enzymes
C) bacterial plasmids
D) anticodons
E) codons
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57
In the study of genetics, the abbreviation PCR refers to
A) purine chain repression.
B) pyrimidine complement restriction.
C) purine coded ribose.
D) protein combination and replication.
E) polymerase chain reaction.
A) purine chain repression.
B) pyrimidine complement restriction.
C) purine coded ribose.
D) protein combination and replication.
E) polymerase chain reaction.
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58
Protease inhibitors, which are effective anti-HIV drugs,
A) are nucleoside analogs.
B) prevent reverse transcription.
C) prevent synthesis of viral proteins.
D) prevent mRNA synthesis.
E) prevent activation of tRNA.
A) are nucleoside analogs.
B) prevent reverse transcription.
C) prevent synthesis of viral proteins.
D) prevent mRNA synthesis.
E) prevent activation of tRNA.
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59
Uracil is a pyrimidine.
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60
A nucleotide consists of only a base and a sugar.
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61
The DNA complement of the sequence 5'-G-C-C-A-T-3' is 3'-G-C-C-A-T-5'.
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62
Match the following.
the nucleic acid that contains the codons for the amino acids of a protein
A)rRNA
B)mRNA
C)tRNA
D)DNA
the nucleic acid that contains the codons for the amino acids of a protein
A)rRNA
B)mRNA
C)tRNA
D)DNA
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63
Match the following.
picks up the specific amino acids for protein synthesis
A)rRNA
B)mRNA
C)tRNA
D)DNA
picks up the specific amino acids for protein synthesis
A)rRNA
B)mRNA
C)tRNA
D)DNA
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64
Match the following.
contains within the nucleus of the cell the information for the synthesis of protein
A)rRNA
B)mRNA
C)tRNA
D)DNA
contains within the nucleus of the cell the information for the synthesis of protein
A)rRNA
B)mRNA
C)tRNA
D)DNA
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65
Match the correct term with the statement.
the portion of a gene that turns the synthesis of a specific mRNA on or off
A)operon
B)operator
C)promotor
D)repressor
the portion of a gene that turns the synthesis of a specific mRNA on or off
A)operon
B)operator
C)promotor
D)repressor
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66
mRNA is the smallest type of RNA.
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67
Human DNA contains many nucleotides that are not used in genes.
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68
AZT is a drug used in the treatment of colds.
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69
Messenger RNA carries protein synthesis information from the nucleus to the ribosomes.
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70
Okazaki fragments are short segments formed by DNA polymerase in the daughter DNA strand that runs in the 3' to 5' direction.
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71
A retrovirus uses DNA as its genetic material.
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72
Match the following.
the nucleic acid that contains a single anticodon for a specific amino acid
A)rRNA
B)mRNA
C)tRNA
D)DNA
the nucleic acid that contains a single anticodon for a specific amino acid
A)rRNA
B)mRNA
C)tRNA
D)DNA
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73
DNA fingerprinting is not yet used to detect genes for cancer susceptibility.
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74
Match the following.
the most abundant nucleic acid in the ribosomes
A)rRNA
B)mRNA
C)tRNA
D)DNA
the most abundant nucleic acid in the ribosomes
A)rRNA
B)mRNA
C)tRNA
D)DNA
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75
Down syndrome is an acquired disease, not a genetic disease.
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76
If the DNA double helix in humans contains 20% guanine, then the percent cytosine is 20%.
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77
Match the following.
synthesized by the DNA to carry the genetic message to the ribosomes
A)rRNA
B)mRNA
C)tRNA
D)DNA
synthesized by the DNA to carry the genetic message to the ribosomes
A)rRNA
B)mRNA
C)tRNA
D)DNA
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78
Human insulin can be made with the use of recombinant DNA technology.
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79
A retrovirus contains DNA as its genetic material and that synthesizes a complementary RNA strand inside a cell.
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80
RNA contains no phosphate.
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