Deck 22: Proteins
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Deck 22: Proteins
1
Which of the following amino acids is not optically active?
A) alanine
B) glycine
C) tryptophan
D) None of these, they are all optically active.
A) alanine
B) glycine
C) tryptophan
D) None of these, they are all optically active.
B
2
Which of the following is not a fibrous protein?
A) actin
B) collagen
C) keratin
D) None, they are all fibrous proteins.
A) actin
B) collagen
C) keratin
D) None, they are all fibrous proteins.
D
3
What is the minimum number of carbon atoms in an α-amino acid?
A) 1
B) 2
C) 3
D) 4
A) 1
B) 2
C) 3
D) 4
B
4
Approximately how many different proteins are found in the human body?
A) 900
B) 9000
C) 100,000
D) 1,000,000
A) 900
B) 9000
C) 100,000
D) 1,000,000
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5
Proteins are associated with which of the following functions?
A) catalysis
B) movement
C) storage
D) all of these
A) catalysis
B) movement
C) storage
D) all of these
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6
Which of the following is a structural protein?
A) cellulose
B) collagen
C) hemoglobin
D) insulin
A) cellulose
B) collagen
C) hemoglobin
D) insulin
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7
How many different amino acids are commonly found in proteins?
A) 10
B) 20
C) 200
D) 1000
A) 10
B) 20
C) 200
D) 1000
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8
In which of the following is the amino nitrogen also part of the side chain?
A) cysteine
B) glycine
C) proline
D) tryptophan
A) cysteine
B) glycine
C) proline
D) tryptophan
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9
Which of the following is a protein associated the storage of iron?
A) actin
B) ferritin
C) hemoglobin
D) insulin
A) actin
B) ferritin
C) hemoglobin
D) insulin
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10
Which of the following is true of the solubility of proteins in water?
A) Both fibrous and globular proteins are generally insoluble in water.
B) Both fibrous and globular proteins are generally soluble in water.
C) Fibrous proteins are generally insoluble in water.
D) Globular proteins are generally insoluble in water.
A) Both fibrous and globular proteins are generally insoluble in water.
B) Both fibrous and globular proteins are generally soluble in water.
C) Fibrous proteins are generally insoluble in water.
D) Globular proteins are generally insoluble in water.
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11
Approximately how many different proteins are found in a typical cell?
A) 900
B) 9000
C) 100,000
D) 1,000,000
A) 900
B) 9000
C) 100,000
D) 1,000,000
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12
Which of the following side chains are hydrophobic?
A) acidic
B) basic
C) polar but neutral
D) none of these
A) acidic
B) basic
C) polar but neutral
D) none of these
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13
Although all biological molecules are important, which type of molecule is considered the most important?
A) amino acids
B) carbohydrates
C) lipids
D) proteins
A) amino acids
B) carbohydrates
C) lipids
D) proteins
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14
Which of the following proteins is a hormone?
A) casein
B) hemoglobin
C) insulin
D) all of these
A) casein
B) hemoglobin
C) insulin
D) all of these
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15
Which of the following is true of the solubility of proteins in water?
A) Both fibrous and globular proteins are generally insoluble in water.
B) Both fibrous and globular proteins are generally soluble in water.
C) Fibrous proteins are generally soluble in water.
D) Globular proteins are generally soluble in water.
A) Both fibrous and globular proteins are generally insoluble in water.
B) Both fibrous and globular proteins are generally soluble in water.
C) Fibrous proteins are generally soluble in water.
D) Globular proteins are generally soluble in water.
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16
What is the most important property of the R groups of the amino acids?
A) their polarity
B) their shape
C) their size
D) none of these
A) their polarity
B) their shape
C) their size
D) none of these
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17
Which of the following is a protein associated with the movement of muscles?
A) actin
B) ferritin
C) hemoglobin
D) insulin
A) actin
B) ferritin
C) hemoglobin
D) insulin
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18
Which of the following side chains are hydrophobic?
A) acidic
B) nonpolar
C) polar but neutral
D) none of these
A) acidic
B) nonpolar
C) polar but neutral
D) none of these
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19
Which functional group is involved in linking together the amino acids of proteins?
A) amine
B) anhydride
C) carbonyl
D) carboxyl
A) amine
B) anhydride
C) carbonyl
D) carboxyl
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20
Which of the following side chains are hydrophilic?
A) acidic
B) basic
C) polar but neutral
D) all of these
A) acidic
B) basic
C) polar but neutral
D) all of these
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21
In which of the following do both amino acids have a polar but neutral side chain?
A) cysteine and methionine
B) cysteine and serine
C) histidine and methionine
D) phenylalanine and tryptophan
A) cysteine and methionine
B) cysteine and serine
C) histidine and methionine
D) phenylalanine and tryptophan
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22
In which of the following do both amino acids contain a sulfur atom?
A) cysteine and glycine
B) cysteine and methionine
C) histidine and methionine
D) phenylalanine and tryptophan
A) cysteine and glycine
B) cysteine and methionine
C) histidine and methionine
D) phenylalanine and tryptophan
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23
Which of the following amino acids has the highest pI?
A) arginine
B) cysteine
C) glycine
D) glutamic acid
A) arginine
B) cysteine
C) glycine
D) glutamic acid
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24
Which of the following explains the unusually high melting points of amino acids?
A) their formula weights
B) the polarity of the side chains
C) the presence of nitrogen atoms
D) their existence as zwitterions
A) their formula weights
B) the polarity of the side chains
C) the presence of nitrogen atoms
D) their existence as zwitterions
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25
In which of the following do both amino acids have a nonpolar side chain?
A) cysteine and glycine
B) cysteine and methionine
C) histidine and methionine
D) phenylalanine and tryptophan
A) cysteine and glycine
B) cysteine and methionine
C) histidine and methionine
D) phenylalanine and tryptophan
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26
Which of the following is true about zwitterions?
A) They are positively charged.
B) They are negatively charged.
C) They are electrically neutral.
D) The charge depends on the zwitterion.
A) They are positively charged.
B) They are negatively charged.
C) They are electrically neutral.
D) The charge depends on the zwitterion.
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27
Which of the following amino acids has the lowest pI?
A) arginine
B) cysteine
C) glycine
D) glutamic acid
A) arginine
B) cysteine
C) glycine
D) glutamic acid
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28
What is the approximate pI of most amino acids?
A) 3
B) 6
C) 7
D) 10
A) 3
B) 6
C) 7
D) 10
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29
Which of the following is true of an amino acid at a pH above its isoelectric point?
A) It will have a negative charge.
B) It will be electrically neutral.
C) It will have a positive charge.
D) We cannot predict its charge.
A) It will have a negative charge.
B) It will be electrically neutral.
C) It will have a positive charge.
D) We cannot predict its charge.
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30
Which of the following is true of all α-amino acids?
A) All α-amino acids are also D-amino acids.
B) All α-amino acids are also L-amino acids.
C) The amino group is attached to the carbon of the carboxyl group.
D) The amino group and the carbon of the carboxyl group are attached to the same carbon atom.
A) All α-amino acids are also D-amino acids.
B) All α-amino acids are also L-amino acids.
C) The amino group is attached to the carbon of the carboxyl group.
D) The amino group and the carbon of the carboxyl group are attached to the same carbon atom.
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31
In which of the following do both amino acids have a basic side chain?
A) cysteine and glycine
B) cysteine and methionine
C) histidine and lysine
D) phenylalanine and tryptophan
A) cysteine and glycine
B) cysteine and methionine
C) histidine and lysine
D) phenylalanine and tryptophan
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32
What type of chemical reaction is involved in the formation of disulfide bonds from thiols?
A) addition
B) reduction
C) oxidation
D) substitution
A) addition
B) reduction
C) oxidation
D) substitution
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33
Which of the following is true of the isoelectric point of amino acids?
A) The isoelectric points of all amino acids are the same.
B) It is the pH at which an amino acid conducts electricity.
C) It is the pH at which an amino acid has equal numbers of positive and negative charges.
D) All of the above are true.
A) The isoelectric points of all amino acids are the same.
B) It is the pH at which an amino acid conducts electricity.
C) It is the pH at which an amino acid has equal numbers of positive and negative charges.
D) All of the above are true.
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34
Which of the following is true of amino acids dissolved in water?
A) They exist in un-ionized form at high pH.
B) They exist in un-ionized form at low pH.
C) They exist at un-ionized form only at the isoelectric point.
D) They do not exist in unionized form at any pH.
A) They exist in un-ionized form at high pH.
B) They exist in un-ionized form at low pH.
C) They exist at un-ionized form only at the isoelectric point.
D) They do not exist in unionized form at any pH.
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35
What determines the characteristics of an amino acid?
A) its molecular weight
B) the identity of its side chain
C) both a and b
D) neither a nor b
A) its molecular weight
B) the identity of its side chain
C) both a and b
D) neither a nor b
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36
Which of the following is true of an amino acid at a pH below its isoelectric point?
A) It will have a negative charge.
B) It will be electrically neutral.
C) It will have a positive charge.
D) We cannot predict its charge.
A) It will have a negative charge.
B) It will be electrically neutral.
C) It will have a positive charge.
D) We cannot predict its charge.
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37
Which of the following is a γ-hydroxy-α-amino acid?
A) asparagine
B) serine
C) threonine
D) none of these
A) asparagine
B) serine
C) threonine
D) none of these
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38
Which of the following is a β-hydroxy-α-amino acid?
A) asparagine
B) serine
C) tryptophan
D) none of these
A) asparagine
B) serine
C) tryptophan
D) none of these
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39
Which of the following amino acids is easily dimerized?
A) alanine
B) cysteine
C) glycine
D) methionine
A) alanine
B) cysteine
C) glycine
D) methionine
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40
Which of the following contains a disulfide bond?
A) alanine
B) cysteine
C) cystine
D) methionine
A) alanine
B) cysteine
C) cystine
D) methionine
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41
Which of the following amino acids is only occasionally found in proteins?
A) asparagine
B) hydroxyproline
C) proline
D) serine
A) asparagine
B) hydroxyproline
C) proline
D) serine
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42
How many amino acids have an amide side chain?
A) 1
B) 2
C) 3
D) 4
A) 1
B) 2
C) 3
D) 4
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43
Which of the following amino acids functions as a hormone?
A) leucine
B) lysine
C) thyroxine
D) tyrosine
A) leucine
B) lysine
C) thyroxine
D) tyrosine
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44
From which amino acid is tyrosine normally derived?
A) cysteine
B) phenylalanine
C) tryptophan
D) valine
A) cysteine
B) phenylalanine
C) tryptophan
D) valine
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45
Which amino acids are precursors of norepinephrine and epinephrine?
A) aspartic acid and glutamic acid
B) cysteine and methionine
C) isoleucine and leucine
D) phenylalanine and tyrosine
A) aspartic acid and glutamic acid
B) cysteine and methionine
C) isoleucine and leucine
D) phenylalanine and tyrosine
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46
What type of chemical reaction is involved in the conversion of cystine to cysteine?
A) addition
B) reduction
C) oxidation
D) substitution
A) addition
B) reduction
C) oxidation
D) substitution
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47
Which of the following amino acids will exist as a -2 ion at very high pH?
A) arginine
B) glutamic acid
C) isoleucine
D) none of these
A) arginine
B) glutamic acid
C) isoleucine
D) none of these
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48
Which of the following amino acids will exist as a + 2 ion at very low pH?
A) arginine
B) glutamic acid
C) isoleucine
D) none of these
A) arginine
B) glutamic acid
C) isoleucine
D) none of these
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49
Serotonin is formed from which amino acid?
A) phenylalanine
B) tryptophan
C) tyrosine
D) valine
A) phenylalanine
B) tryptophan
C) tyrosine
D) valine
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50
Which of the following amino acids has iodine atoms in its structure?
A) leucine
B) lysine
C) thyroxine
D) tyrosine
A) leucine
B) lysine
C) thyroxine
D) tyrosine
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51
Which of the following amino acids absorbs UV radiation at 280 nm?
A) arginine
B) alanine
C) leucine
D) tyrosine
A) arginine
B) alanine
C) leucine
D) tyrosine
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52
Which of the following amino acids will exist as a -2 ion at very low pH?
A) asparagine
B) glutamic acid
C) isoleucine
D) none of these
A) asparagine
B) glutamic acid
C) isoleucine
D) none of these
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53
What type of chemical reaction is involved in the conversion of disulfide bonds to thiols?
A) addition
B) reduction
C) oxidation
D) substitution
A) addition
B) reduction
C) oxidation
D) substitution
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54
How many amino acids have acidic side chains?
A) 1
B) 2
C) 3
D) 4
A) 1
B) 2
C) 3
D) 4
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55
Neurotransmitters known as catecholamines are formed from which amino acid?
A) cysteine
B) threonine
C) tyrosine
D) valine
A) cysteine
B) threonine
C) tyrosine
D) valine
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56
Which of the following amino acids absorbs UV radiation at 280 nm?
A) phenylalanine
B) tryptophan
C) tyrosine
D) all of these
A) phenylalanine
B) tryptophan
C) tyrosine
D) all of these
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57
What type of chemical reaction is involved in the formation of cystine from cysteine?
A) addition
B) reduction
C) oxidation
D) substitution
A) addition
B) reduction
C) oxidation
D) substitution
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58
Which protein contains hydroxylysine and hydroxyproline?
A) actin
B) collagen
C) fibrinogen
D) hemoglobin
A) actin
B) collagen
C) fibrinogen
D) hemoglobin
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59
How many amino acids have basic side chains?
A) 1
B) 2
C) 3
D) 4
A) 1
B) 2
C) 3
D) 4
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60
Which amino acid can be found in proteins in both its protonated and unprotonated forms?
A) alanine
B) glycine
C) histidine
D) phenylalanine
A) alanine
B) glycine
C) histidine
D) phenylalanine
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61
When will a protein have a net positive charge?
A) always
B) never
C) when the pH is above its isoelectric point
D) when the pH is below its isoelectric point
A) always
B) never
C) when the pH is above its isoelectric point
D) when the pH is below its isoelectric point
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62
Which of the following describes the atomic makeup of the backbone unit of a protein?
A) 2 carbon atoms, 2 nitrogen atoms, 2 oxygen atoms
B) 3 carbon atoms, 2 nitrogen atoms, 2 oxygen atoms, 1 hydrogen atom
C) 3 carbon atoms, 1 nitrogen atom, 1 oxygen atom, 1 hydrogen atom
D) 3 carbon atoms, 2 nitrogen atoms, 2 oxygen atoms, 2 hydrogen atoms
A) 2 carbon atoms, 2 nitrogen atoms, 2 oxygen atoms
B) 3 carbon atoms, 2 nitrogen atoms, 2 oxygen atoms, 1 hydrogen atom
C) 3 carbon atoms, 1 nitrogen atom, 1 oxygen atom, 1 hydrogen atom
D) 3 carbon atoms, 2 nitrogen atoms, 2 oxygen atoms, 2 hydrogen atoms
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63
Which of the following is true of proteins?
A) All proteins are acidic.
B) All proteins are basic.
C) All proteins are neutral.
D) The acid/base properties of a protein depend on the identity of its side chains.
A) All proteins are acidic.
B) All proteins are basic.
C) All proteins are neutral.
D) The acid/base properties of a protein depend on the identity of its side chains.
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64
How many dipeptides can be made using the 20 standard amino acids?
A) 20
B) 40
C) 200
D) 400
A) 20
B) 40
C) 200
D) 400
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65
When will a protein have the lowest solubility?
A) when the pH is very low
B) when the pH = 7
C) when the pH is very high
D) at its isoelectric point
A) when the pH is very low
B) when the pH = 7
C) when the pH is very high
D) at its isoelectric point
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66
What is a residue?
A) An amino acid which has been severed from a protein.
B) Any individual amino acid in a protein or polypeptide.
C) The portion of a protein which remains after one amino acid has been removed from the C-terminus.
D) The portion of a protein which remains after one amino acid has been removed from the N-terminus.
A) An amino acid which has been severed from a protein.
B) Any individual amino acid in a protein or polypeptide.
C) The portion of a protein which remains after one amino acid has been removed from the C-terminus.
D) The portion of a protein which remains after one amino acid has been removed from the N-terminus.
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67
How is the tripeptide shown designated? 
A) Ala-Cys-Asp
B) Ala-Cys-Glu
C) Asp-Cys-Ala
D) Glu-Cys-Ala

A) Ala-Cys-Asp
B) Ala-Cys-Glu
C) Asp-Cys-Ala
D) Glu-Cys-Ala
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68
What is the relationship between Ala−Gly and Gly−Ala?
A) They are the same substance.
B) They are allotropes.
C) They are isomers.
D) They are mirror images.
A) They are the same substance.
B) They are allotropes.
C) They are isomers.
D) They are mirror images.
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69
Using the 20 standard amino acids how many dipeptides containing two different amino acids can be made?
A) 20
B) 39
C) 40
D) 380
A) 20
B) 39
C) 40
D) 380
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70
Which of the following is true of the atoms in the backbone unit of a protein?
A) They all are in a straight line.
B) They are all in the same plane.
C) They all have tetrahedral geometry.
D) None of these is correct.
A) They all are in a straight line.
B) They are all in the same plane.
C) They all have tetrahedral geometry.
D) None of these is correct.
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71
Which of the following defines the primary structure of proteins?
A) the geometric arrangement of the backbone atoms
B) the geometric arrangement of the side chains
C) the sequence of the amino acids
D) all of the above
A) the geometric arrangement of the backbone atoms
B) the geometric arrangement of the side chains
C) the sequence of the amino acids
D) all of the above
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72
Which of the following is alanylglycine?
A)
B)
C)
D)
A)

B)

C)

D)

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73
When will a protein have a net negative charge?
A) always
B) never
C) when the pH is above its isoelectric point
D) when the pH is below its isoelectric point
A) always
B) never
C) when the pH is above its isoelectric point
D) when the pH is below its isoelectric point
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74
How is the tripeptide designated? 
A) Ala-Cys-Asp
B) Ala-Cys-Glu
C) Asp-Cys-Ala
D) Glu-Cys-Ala

A) Ala-Cys-Asp
B) Ala-Cys-Glu
C) Asp-Cys-Ala
D) Glu-Cys-Ala
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75
When naming a protein or polypeptide which of the following is true?
A) The convention for proteins is different from that for polypeptides.
B) They are named from the C-terminus to the N-terminus.
C) They are named from the middle towards the two ends.
D) They are named from the N-terminus to the C-terminus.
A) The convention for proteins is different from that for polypeptides.
B) They are named from the C-terminus to the N-terminus.
C) They are named from the middle towards the two ends.
D) They are named from the N-terminus to the C-terminus.
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76
Which of the following is glycylalanine?
A)
B)
C)
D)
A)

B)

C)

D)

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77
Protein synthesis proceeds in which direction?
A) from the C-terminus to the N-terminus
B) from the middle towards the two ends
C) from the N-terminus to the C-terminus
D) the direction varies from one protein to another
A) from the C-terminus to the N-terminus
B) from the middle towards the two ends
C) from the N-terminus to the C-terminus
D) the direction varies from one protein to another
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78
Which of the following is serylalanine?
A)
B)
C)
D)
A)

B)

C)

D)

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79
Which of the following is alanylserine?
A)
B)
C)
D)
A)

B)

C)

D)

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80
How many atoms form the backbone of the repeat unit of a protein?
A) 2
B) 4
C) 6
D) 8
A) 2
B) 4
C) 6
D) 8
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