Microbiology: A Systems Approach 4th Edition by Marjorie Kelly Cowan

Exercise 37

Describe how the immune system distinguishes foreign cells from cells deemed as self.
b. Type I diabetes may be triggered by immune cells attacking one's own insulin-secreting pancreatic cells. Research shows that this may occur in an individual after a viral infection. Develop a hypothesis to explain this situation, explaining how PAMPs may play a role in this process.