Genetics: Analysis and Principles 5th Edition by Robert Brooker

Exercise 15

When studying living cells in a laboratory, researchers sometimes use drugs as a way to cause cells to remain in a particular phase of the cell cycle. For example, aphidicolin inhibits DNA synthesis in eukaryotic cells and causes them to remain in the G 1 phase because they cannot replicate their DNA. In what phase of the cell cycle-G 1 , S, G 2 , prophase, metaphase, anaphase, or telophase-would you expect somatic cells to stay if the following types of drug were added
a. A drug that inhibits microtubule formation
B. A drug that allows microtubules to form but prevents them from shortening
C. A drug that inhibits cytokinesis
D. A drug that prevents chromosomal condensation